QUESTDB_website/static/js/ChemDoodleWeb.js

//
// ChemDoodle Web Components 9.1.0
//
// https://web.chemdoodle.com
//
// Copyright 2009-2020 iChemLabs, LLC.  All rights reserved.
//
// The ChemDoodle Web Components library is licensed under version 3
// of the GNU GENERAL PUBLIC LICENSE.
//
// You may redistribute it and/or modify it under the terms of the
// GNU General Public License as published by the Free Software Foundation,
// either version 3 of the License, or (at your option) any later version.
//
// As an exception to the GPL, you may distribute this packed form of
// the code without the copy of the GPL license normally required,
// provided you include this license notice and a URL through which
// recipients can access the corresponding unpacked source code. 
//
// This program is distributed in the hope that it will be useful,
// but WITHOUT ANY WARRANTY; without even the implied warranty of
// MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
// GNU General Public License for more details.
//
// ChemDoodle Web Components employs 3rd party libraries under the MIT
// license. For a full list with links to the original source, go to:
// https://web.chemdoodle.com/installation/download/#libraries
//
// Please contact iChemLabs <https://www.ichemlabs.com/contact-us> for
// alternate licensing options.
//
'use strict';let ChemDoodle=function(){let f={iChemLabs:{},informatics:{},io:{},lib:{},notations:{},structures:{}};f.structures.d2={};f.structures.d3={};f.getVersion=function(){return"9.1.0"};return f}();
(function(f,q,n){(function(f,e){"object"===typeof module&&"object"===typeof module.exports?module.exports=f.document?e(f,!0):function(k){if(!k.document)throw Error("jQuery requires a window with a document");return e(k)}:e(f)})("undefined"!==typeof f?f:this,function(f,e){function k(c){var a=!!c&&"length"in c&&c.length,b=t.type(c);return"function"===b||t.isWindow(c)?!1:"array"===b||0===a||"number"===typeof a&&0<a&&a-1 in c}function b(c,a,b){if(t.isFunction(a))return t.grep(c,function(c,d){return!!a.call(c,
d,c)!==b});if(a.nodeType)return t.grep(c,function(c){return c===a!==b});if("string"===typeof a){if(nb.test(a))return t.filter(a,c,b);a=t.filter(a,c)}return t.grep(c,function(c){return-1<ha.call(a,c)!==b})}function d(c,a){for(;(c=c[a])&&1!==c.nodeType;);return c}function h(c){var a={};t.each(c.match(ia)||[],function(c,b){a[b]=!0});return a}function a(){I.removeEventListener("DOMContentLoaded",a);f.removeEventListener("load",a);t.ready()}function g(){this.expando=t.expando+g.uid++}function l(c,a,b){if(b===
n&&1===c.nodeType)if(b="data-"+a.replace(Ta,"-$\x26").toLowerCase(),b=c.getAttribute(b),"string"===typeof b){try{b="true"===b?!0:"false"===b?!1:"null"===b?null:+b+""===b?+b:ob.test(b)?t.parseJSON(b):b}catch(bc){}W.set(c,a,b)}else b=n;return b}function v(c,a,b,d){var g=1,p=20,h=d?function(){return d.cur()}:function(){return t.css(c,a,"")},F=h(),e=b&&b[3]||(t.cssNumber[a]?"":"px"),m=(t.cssNumber[a]||"px"!==e&&+F)&&va.exec(t.css(c,a));if(m&&m[3]!==e){e=e||m[3];b=b||[];m=+F||1;do g=g||".5",m/=g,t.style(c,
a,m+e);while(g!==(g=h()/F)&&1!==g&&--p)}if(b){m=+m||+F||0;var l=b[1]?m+(b[1]+1)*b[2]:+b[2];d&&(d.unit=e,d.start=m,d.end=l)}return l}function m(c,a){var b="undefined"!==typeof c.getElementsByTagName?c.getElementsByTagName(a||"*"):"undefined"!==typeof c.querySelectorAll?c.querySelectorAll(a||"*"):[];return a===n||a&&t.nodeName(c,a)?t.merge([c],b):b}function x(c,a){for(var b=0,d=c.length;b<d;b++)L.set(c[b],"globalEval",!a||L.get(a[b],"globalEval"))}function u(c,a,b,d,g){for(var p,h,F,e=a.createDocumentFragment(),
l=[],f=0,v=c.length;f<v;f++)if((p=c[f])||0===p)if("object"===t.type(p))t.merge(l,p.nodeType?[p]:p);else if(qb.test(p)){h=h||e.appendChild(a.createElement("div"));F=(Ua.exec(p)||["",""])[1].toLowerCase();F=ba[F]||ba._default;h.innerHTML=F[1]+t.htmlPrefilter(p)+F[2];for(F=F[0];F--;)h=h.lastChild;t.merge(l,h.childNodes);h=e.firstChild;h.textContent=""}else l.push(a.createTextNode(p));e.textContent="";for(f=0;p=l[f++];)if(d&&-1<t.inArray(p,d))g&&g.push(p);else if(c=t.contains(p.ownerDocument,p),h=m(e.appendChild(p),
"script"),c&&x(h),b)for(F=0;p=h[F++];)Va.test(p.type||"")&&b.push(p);return e}function w(){return!0}function r(){return!1}function y(){try{return I.activeElement}catch(F){}}function c(a,b,d,g,p,h){var F;if("object"===typeof b){"string"!==typeof d&&(g=g||d,d=n);for(F in b)c(a,F,d,g,b[F],h);return a}null==g&&null==p?(p=d,g=d=n):null==p&&("string"===typeof d?(p=g,g=n):(p=g,g=d,d=n));if(!1===p)p=r;else if(!p)return a;if(1===h){var e=p;p=function(c){t().off(c);return e.apply(this,arguments)};p.guid=e.guid||
(e.guid=t.guid++)}return a.each(function(){t.event.add(this,b,p,g,d)})}function p(c,a){return t.nodeName(c,"table")&&t.nodeName(11!==a.nodeType?a:a.firstChild,"tr")?c.getElementsByTagName("tbody")[0]||c.appendChild(c.ownerDocument.createElement("tbody")):c}function A(c){c.type=(null!==c.getAttribute("type"))+"/"+c.type;return c}function C(c){var a=rb.exec(c.type);a?c.type=a[1]:c.removeAttribute("type");return c}function B(c,a){var b,d;if(1===a.nodeType){if(L.hasData(c)){var g=L.access(c);var p=L.set(a,
g);if(g=g.events)for(d in delete p.handle,p.events={},g)for(p=0,b=g[d].length;p<b;p++)t.event.add(a,d,g[d][p])}W.hasData(c)&&(c=W.access(c),c=t.extend({},c),W.set(a,c))}}function q(c,a,b,d){a=Da.apply([],a);var g,p=0,h=c.length,e=h-1,F=a[0],l=t.isFunction(F);if(l||1<h&&"string"===typeof F&&!P.checkClone&&sb.test(F))return c.each(function(g){var p=c.eq(g);l&&(a[0]=F.call(this,g,p.html()));q(p,a,b,d)});if(h){var f=u(a,c[0].ownerDocument,!1,c,d);var v=f.firstChild;1===f.childNodes.length&&(f=v);if(v||
d){v=t.map(m(f,"script"),A);for(g=v.length;p<h;p++){var k=f;p!==e&&(k=t.clone(k,!0,!0),g&&t.merge(v,m(k,"script")));b.call(c[p],k,p)}if(g)for(f=v[v.length-1].ownerDocument,t.map(v,C),p=0;p<g;p++)k=v[p],Va.test(k.type||"")&&!L.access(k,"globalEval")&&t.contains(f,k)&&(k.src?t._evalUrl&&t._evalUrl(k.src):t.globalEval(k.textContent.replace(ub,"")))}}return c}function E(c,a,b){for(var d=a?t.filter(a,c):c,g=0;null!=(a=d[g]);g++)b||1!==a.nodeType||t.cleanData(m(a)),a.parentNode&&(b&&t.contains(a.ownerDocument,
a)&&x(m(a,"script")),a.parentNode.removeChild(a));return c}function K(c,a){c=t(a.createElement(c)).appendTo(a.body);a=t.css(c[0],"display");c.detach();return a}function G(c){var a=I,b=Wa[c];b||(b=K(c,a),"none"!==b&&b||(Ea=(Ea||t("\x3ciframe frameborder\x3d'0' width\x3d'0' height\x3d'0'/\x3e")).appendTo(a.documentElement),a=Ea[0].contentDocument,a.write(),a.close(),b=K(c,a),Ea.detach()),Wa[c]=b);return b}function J(c,a,b){var d=c.style;var g=(b=b||Fa(c))?b.getPropertyValue(a)||b[a]:n;""!==g&&g!==n||
t.contains(c.ownerDocument,c)||(g=t.style(c,a));if(b&&!P.pixelMarginRight()&&Ja.test(g)&&Xa.test(a)){c=d.width;a=d.minWidth;var p=d.maxWidth;d.minWidth=d.maxWidth=d.width=g;g=b.width;d.width=c;d.minWidth=a;d.maxWidth=p}return g!==n?g+"":g}function H(c,a){return{get:function(){if(c())delete this.get;else return(this.get=a).apply(this,arguments)}}}function X(c){if(c in Ya)return c;for(var a=c[0].toUpperCase()+c.slice(1),b=Za.length;b--;)if(c=Za[b]+a,c in Ya)return c}function na(c,a,b){return(c=va.exec(a))?
Math.max(0,c[2]-(b||0))+(c[3]||"px"):a}function Q(c,a,b,d,g){a=b===(d?"border":"content")?4:"width"===a?1:0;for(var p=0;4>a;a+=2)"margin"===b&&(p+=t.css(c,b+ka[a],!0,g)),d?("content"===b&&(p-=t.css(c,"padding"+ka[a],!0,g)),"margin"!==b&&(p-=t.css(c,"border"+ka[a]+"Width",!0,g))):(p+=t.css(c,"padding"+ka[a],!0,g),"padding"!==b&&(p+=t.css(c,"border"+ka[a]+"Width",!0,g)));return p}function ca(c,a,b){var d=!0,g="width"===a?c.offsetWidth:c.offsetHeight,p=Fa(c),h="border-box"===t.css(c,"boxSizing",!1,p);
if(0>=g||null==g){g=J(c,a,p);if(0>g||null==g)g=c.style[a];if(Ja.test(g))return g;d=h&&(P.boxSizingReliable()||g===c.style[a]);g=parseFloat(g)||0}return g+Q(c,a,b||(h?"border":"content"),d,p)+"px"}function da(c,a){for(var b,d,g,p=[],h=0,e=c.length;h<e;h++)d=c[h],d.style&&(p[h]=L.get(d,"olddisplay"),b=d.style.display,a?(p[h]||"none"!==b||(d.style.display=""),""===d.style.display&&wa(d)&&(p[h]=L.access(d,"olddisplay",G(d.nodeName)))):(g=wa(d),"none"===b&&g||L.set(d,"olddisplay",g?b:t.css(d,"display"))));
for(h=0;h<e;h++)d=c[h],!d.style||a&&"none"!==d.style.display&&""!==d.style.display||(d.style.display=a?p[h]||"":"none");return c}function M(c,a,b,d,g){return new M.prototype.init(c,a,b,d,g)}function oa(){f.setTimeout(function(){pa=n});return pa=t.now()}function qa(c,a){var b=0,d={height:c};for(a=a?1:0;4>b;b+=2-a){var g=ka[b];d["margin"+g]=d["padding"+g]=c}a&&(d.opacity=d.width=c);return d}function ra(c,a,b){for(var d,g=(V.tweeners[a]||[]).concat(V.tweeners["*"]),p=0,h=g.length;p<h;p++)if(d=g[p].call(b,
a,c))return d}function sa(c,a){var b,d;for(b in c){var g=t.camelCase(b);var p=a[g];var h=c[b];t.isArray(h)&&(p=h[1],h=c[b]=h[0]);b!==g&&(c[g]=h,delete c[b]);if((d=t.cssHooks[g])&&"expand"in d)for(b in h=d.expand(h),delete c[g],h)b in c||(c[b]=h[b],a[b]=p);else a[g]=p}}function V(c,a,b){var d,g=0,p=V.prefilters.length,h=t.Deferred().always(function(){delete e.elem}),e=function(){if(d)return!1;var a=pa||oa();a=Math.max(0,m.startTime+m.duration-a);for(var b=1-(a/m.duration||0),g=0,p=m.tweens.length;g<
p;g++)m.tweens[g].run(b);h.notifyWith(c,[m,b,a]);if(1>b&&p)return a;h.resolveWith(c,[m]);return!1},m=h.promise({elem:c,props:t.extend({},a),opts:t.extend(!0,{specialEasing:{},easing:t.easing._default},b),originalProperties:a,originalOptions:b,startTime:pa||oa(),duration:b.duration,tweens:[],createTween:function(a,b){a=t.Tween(c,m.opts,a,b,m.opts.specialEasing[a]||m.opts.easing);m.tweens.push(a);return a},stop:function(a){var b=0,g=a?m.tweens.length:0;if(d)return this;for(d=!0;b<g;b++)m.tweens[b].run(1);
a?(h.notifyWith(c,[m,1,0]),h.resolveWith(c,[m,a])):h.rejectWith(c,[m,a]);return this}});b=m.props;for(sa(b,m.opts.specialEasing);g<p;g++)if(a=V.prefilters[g].call(m,c,b,m.opts))return t.isFunction(a.stop)&&(t._queueHooks(m.elem,m.opts.queue).stop=t.proxy(a.stop,a)),a;t.map(b,ra,m);t.isFunction(m.opts.start)&&m.opts.start.call(c,m);t.fx.timer(t.extend(e,{elem:c,anim:m,queue:m.opts.queue}));return m.progress(m.opts.progress).done(m.opts.done,m.opts.complete).fail(m.opts.fail).always(m.opts.always)}
function Y(c){return c.getAttribute&&c.getAttribute("class")||""}function T(c){return function(a,b){"string"!==typeof a&&(b=a,a="*");var d=0,g=a.toLowerCase().match(ia)||[];if(t.isFunction(b))for(;a=g[d++];)"+"===a[0]?(a=a.slice(1)||"*",(c[a]=c[a]||[]).unshift(b)):(c[a]=c[a]||[]).push(b)}}function R(c,a,b,d){function g(e){var m;p[e]=!0;t.each(c[e]||[],function(c,e){c=e(a,b,d);if("string"===typeof c&&!h&&!p[c])return a.dataTypes.unshift(c),g(c),!1;if(h)return!(m=c)});return m}var p={},h=c===Ka;return g(a.dataTypes[0])||
!p["*"]&&g("*")}function N(c,a){var b,d,g=t.ajaxSettings.flatOptions||{};for(b in a)a[b]!==n&&((g[b]?c:d||(d={}))[b]=a[b]);d&&t.extend(!0,c,d);return c}function S(c,a,b,d){var g;if(t.isArray(a))t.each(a,function(a,g){b||vb.test(c)?d(c,g):S(c+"["+("object"===typeof g&&null!=g?a:"")+"]",g,b,d)});else if(b||"object"!==t.type(a))d(c,a);else for(g in a)S(c+"["+g+"]",a[g],b,d)}function aa(c){return t.isWindow(c)?c:9===c.nodeType&&c.defaultView}var Z=[],I=f.document,ja=Z.slice,Da=Z.concat,xa=Z.push,ha=Z.indexOf,
ta={},ua=ta.toString,ma=ta.hasOwnProperty,P={},t=function(c,a){return new t.fn.init(c,a)},La=/^[\s\uFEFF\xA0]+|[\s\uFEFF\xA0]+$/g,wb=/^-ms-/,xb=/-([\da-z])/gi,yb=function(c,a){return a.toUpperCase()};t.fn=t.prototype={jquery:"2.2.4",constructor:t,selector:"",length:0,toArray:function(){return ja.call(this)},get:function(c){return null!=c?0>c?this[c+this.length]:this[c]:ja.call(this)},pushStack:function(c){c=t.merge(this.constructor(),c);c.prevObject=this;c.context=this.context;return c},each:function(c){return t.each(this,
c)},map:function(c){return this.pushStack(t.map(this,function(a,b){return c.call(a,b,a)}))},slice:function(){return this.pushStack(ja.apply(this,arguments))},first:function(){return this.eq(0)},last:function(){return this.eq(-1)},eq:function(c){var a=this.length;c=+c+(0>c?a:0);return this.pushStack(0<=c&&c<a?[this[c]]:[])},end:function(){return this.prevObject||this.constructor()},push:xa,sort:Z.sort,splice:Z.splice};t.extend=t.fn.extend=function(){var c,a,b,d=arguments[0]||{},g=1,p=arguments.length,
h=!1;"boolean"===typeof d&&(h=d,d=arguments[g]||{},g++);"object"===typeof d||t.isFunction(d)||(d={});g===p&&(d=this,g--);for(;g<p;g++)if(null!=(c=arguments[g]))for(a in c){var e=d[a];var m=c[a];d!==m&&(h&&m&&(t.isPlainObject(m)||(b=t.isArray(m)))?(b?(b=!1,e=e&&t.isArray(e)?e:[]):e=e&&t.isPlainObject(e)?e:{},d[a]=t.extend(h,e,m)):m!==n&&(d[a]=m))}return d};t.extend({expando:"jQuery"+("2.2.4"+Math.random()).replace(/\D/g,""),isReady:!0,error:function(c){throw Error(c);},noop:function(){},isFunction:function(c){return"function"===
t.type(c)},isArray:Array.isArray,isWindow:function(c){return null!=c&&c===c.window},isNumeric:function(c){var a=c&&c.toString();return!t.isArray(c)&&0<=a-parseFloat(a)+1},isPlainObject:function(c){var a;if("object"!==t.type(c)||c.nodeType||t.isWindow(c)||c.constructor&&!ma.call(c,"constructor")&&!ma.call(c.constructor.prototype||{},"isPrototypeOf"))return!1;for(a in c);return a===n||ma.call(c,a)},isEmptyObject:function(c){for(var a in c)return!1;return!0},type:function(c){return null==c?c+"":"object"===
typeof c||"function"===typeof c?ta[ua.call(c)]||"object":typeof c},globalEval:function(c){var a=eval;if(c=t.trim(c))1===c.indexOf("use strict")?(a=I.createElement("script"),a.text=c,I.head.appendChild(a).parentNode.removeChild(a)):a(c)},camelCase:function(c){return c.replace(wb,"ms-").replace(xb,yb)},nodeName:function(c,a){return c.nodeName&&c.nodeName.toLowerCase()===a.toLowerCase()},each:function(c,a){var b,d=0;if(k(c))for(b=c.length;d<b&&!1!==a.call(c[d],d,c[d]);d++);else for(d in c)if(!1===a.call(c[d],
d,c[d]))break;return c},trim:function(c){return null==c?"":(c+"").replace(La,"")},makeArray:function(c,a){a=a||[];null!=c&&(k(Object(c))?t.merge(a,"string"===typeof c?[c]:c):xa.call(a,c));return a},inArray:function(c,a,b){return null==a?-1:ha.call(a,c,b)},merge:function(c,a){for(var b=+a.length,d=0,g=c.length;d<b;d++)c[g++]=a[d];c.length=g;return c},grep:function(c,a,b){for(var d=[],g=0,p=c.length,h=!b;g<p;g++)b=!a(c[g],g),b!==h&&d.push(c[g]);return d},map:function(c,a,b){var d,g=0,p=[];if(k(c))for(d=
c.length;g<d;g++){var h=a(c[g],g,b);null!=h&&p.push(h)}else for(g in c)h=a(c[g],g,b),null!=h&&p.push(h);return Da.apply([],p)},guid:1,proxy:function(c,a){if("string"===typeof a){var b=c[a];a=c;c=b}if(!t.isFunction(c))return n;var d=ja.call(arguments,2);b=function(){return c.apply(a||this,d.concat(ja.call(arguments)))};b.guid=c.guid=c.guid||t.guid++;return b},now:Date.now,support:P});"function"===typeof Symbol&&(t.fn[Symbol.iterator]=Z[Symbol.iterator]);t.each("Boolean Number String Function Array Date RegExp Object Error Symbol".split(" "),
function(c,a){ta["[object "+a+"]"]=a.toLowerCase()});var ea=function(c){function a(c,a,b,d){var g,p,h,e,m=a&&a.ownerDocument,l=a?a.nodeType:9;b=b||[];if("string"!==typeof c||!c||1!==l&&9!==l&&11!==l)return b;if(!d&&((a?a.ownerDocument||a:X)!==B&&ea(a),a=a||B,D)){if(11!==l&&(e=W.exec(c)))if(g=e[1])if(9===l)if(p=a.getElementById(g)){if(p.id===g)return b.push(p),b}else return b;else{if(m&&(p=m.getElementById(g))&&J(a,p)&&p.id===g)return b.push(p),b}else{if(e[2])return ha.apply(b,a.getElementsByTagName(c)),
b;if((g=e[3])&&U.getElementsByClassName&&a.getElementsByClassName)return ha.apply(b,a.getElementsByClassName(g)),b}if(!(!U.qsa||ca[c+" "]||E&&E.test(c))){if(1!==l){m=a;var v=c}else if("object"!==a.nodeName.toLowerCase()){(h=a.getAttribute("id"))?h=h.replace(La,"\\$\x26"):a.setAttribute("id",h=H);e=fa(c);g=e.length;for(p=ta.test(h)?"#"+h:"[id\x3d'"+h+"']";g--;)e[g]=p+" "+k(e[g]);v=e.join(",");m=ma.test(c)&&f(a.parentNode)||a}if(v)try{return ha.apply(b,m.querySelectorAll(v)),b}catch(gc){}finally{h===
H&&a.removeAttribute("id")}}}return pa(c.replace(Z,"$1"),a,b,d)}function b(){function c(b,d){a.push(b+" ")>O.cacheLength&&delete c[a.shift()];return c[b+" "]=d}var a=[];return c}function d(c){c[H]=!0;return c}function g(c){var a=B.createElement("div");try{return!!c(a)}catch(ec){return!1}finally{a.parentNode&&a.parentNode.removeChild(a)}}function p(c,a){c=c.split("|");for(var b=c.length;b--;)O.attrHandle[c[b]]=a}function h(c,a){var b=a&&c,d=b&&1===c.nodeType&&1===a.nodeType&&(~a.sourceIndex||-2147483648)-
(~c.sourceIndex||-2147483648);if(d)return d;if(b)for(;b=b.nextSibling;)if(b===a)return-1;return c?1:-1}function e(c){return function(a){return"input"===a.nodeName.toLowerCase()&&a.type===c}}function m(c){return function(a){var b=a.nodeName.toLowerCase();return("input"===b||"button"===b)&&a.type===c}}function l(c){return d(function(a){a=+a;return d(function(b,d){for(var g,p=c([],b.length,a),h=p.length;h--;)b[g=p[h]]&&(b[g]=!(d[g]=b[g]))})})}function f(c){return c&&"undefined"!==typeof c.getElementsByTagName&&
c}function v(){}function k(c){for(var a=0,b=c.length,d="";a<b;a++)d+=c[a].value;return d}function F(c,a,b){var d=a.dir,g=b&&"parentNode"===d,p=M++;return a.first?function(a,b,p){for(;a=a[d];)if(1===a.nodeType||g)return c(a,b,p)}:function(a,b,h){var e,m=[Q,p];if(h)for(;a=a[d];){if((1===a.nodeType||g)&&c(a,b,h))return!0}else for(;a=a[d];)if(1===a.nodeType||g){var l=a[H]||(a[H]={});l=l[a.uniqueID]||(l[a.uniqueID]={});if((e=l[d])&&e[0]===Q&&e[1]===p)return m[2]=e[2];l[d]=m;if(m[2]=c(a,b,h))return!0}}}
function A(c){return 1<c.length?function(a,b,d){for(var g=c.length;g--;)if(!c[g](a,b,d))return!1;return!0}:c[0]}function u(c,a,b,d,g){for(var p,h=[],e=0,m=c.length,l=null!=a;e<m;e++)if(p=c[e])if(!b||b(p,d,g))h.push(p),l&&a.push(e);return h}function x(c,b,g,p,h,e){p&&!p[H]&&(p=x(p));h&&!h[H]&&(h=x(h,e));return d(function(d,e,m,l){var f,v=[],k=[],F=e.length,A;if(!(A=d)){A=b||"*";for(var x=m.nodeType?[m]:m,w=[],r=0,n=x.length;r<n;r++)a(A,x[r],w);A=w}A=!c||!d&&b?A:u(A,v,c,m,l);x=g?h||(d?c:F||p)?[]:e:
A;g&&g(A,x,m,l);if(p){var z=u(x,k);p(z,[],m,l);for(m=z.length;m--;)if(f=z[m])x[k[m]]=!(A[k[m]]=f)}if(d){if(h||c){if(h){z=[];for(m=x.length;m--;)(f=x[m])&&z.push(A[m]=f);h(null,x=[],z,l)}for(m=x.length;m--;)(f=x[m])&&-1<(z=h?N(d,f):v[m])&&(d[z]=!(e[z]=f))}}else x=u(x===e?x.splice(F,x.length):x),h?h(null,e,x,l):ha.apply(e,x)})}function w(c){var a,b,d=c.length,g=O.relative[c[0].type];var p=g||O.relative[" "];for(var h=g?1:0,e=F(function(c){return c===a},p,!0),m=F(function(c){return-1<N(a,c)},p,!0),l=
[function(c,b,d){c=!g&&(d||b!==t)||((a=b).nodeType?e(c,b,d):m(c,b,d));a=null;return c}];h<d;h++)if(p=O.relative[c[h].type])l=[F(A(l),p)];else{p=O.filter[c[h].type].apply(null,c[h].matches);if(p[H]){for(b=++h;b<d&&!O.relative[c[b].type];b++);return x(1<h&&A(l),1<h&&k(c.slice(0,h-1).concat({value:" "===c[h-2].type?"*":""})).replace(Z,"$1"),p,h<b&&w(c.slice(h,b)),b<d&&w(c=c.slice(b)),b<d&&k(c))}l.push(p)}return A(l)}function r(c,b){var g=0<b.length,p=0<c.length,h=function(d,h,e,m,l){var f,v,k=0,F="0",
A=d&&[],x=[],w=t,r=d||p&&O.find.TAG("*",l),n=Q+=null==w?1:Math.random()||.1,z=r.length;for(l&&(t=h===B||h||l);F!==z&&null!=(f=r[F]);F++){if(p&&f){var Ia=0;h||f.ownerDocument===B||(ea(f),e=!D);for(;v=c[Ia++];)if(v(f,h||B,e)){m.push(f);break}l&&(Q=n)}g&&((f=!v&&f)&&k--,d&&A.push(f))}k+=F;if(g&&F!==k){for(Ia=0;v=b[Ia++];)v(A,x,h,e);if(d){if(0<k)for(;F--;)A[F]||x[F]||(x[F]=qa.call(m));x=u(x)}ha.apply(m,x);l&&!d&&0<x.length&&1<k+b.length&&a.uniqueSort(m)}l&&(Q=n,t=w);return A};return g?d(h):h}var z,t,
C,y,B,q,D,E,G,K,J,H="sizzle"+1*new Date,X=c.document,Q=0,M=0,I=b(),na=b(),ca=b(),da=function(c,a){c===a&&(y=!0);return 0},V={}.hasOwnProperty,aa=[],qa=aa.pop,L=aa.push,ha=aa.push,ra=aa.slice,N=function(c,a){for(var b=0,d=c.length;b<d;b++)if(c[b]===a)return b;return-1},sa=/[\x20\t\r\n\f]+/g,Z=/^[\x20\t\r\n\f]+|((?:^|[^\\])(?:\\.)*)[\x20\t\r\n\f]+$/g,P=/^[\x20\t\r\n\f]*,[\x20\t\r\n\f]*/,xa=/^[\x20\t\r\n\f]*([>+~]|[\x20\t\r\n\f])[\x20\t\r\n\f]*/,Da=/=[\x20\t\r\n\f]*([^\]'"]*?)[\x20\t\r\n\f]*\]/g,oa=
/:((?:\\.|[\w-]|[^\x00-\xa0])+)(?:\((('((?:\\.|[^\\'])*)'|"((?:\\.|[^\\"])*)")|((?:\\.|[^\\()[\]]|\[[\x20\t\r\n\f]*((?:\\.|[\w-]|[^\x00-\xa0])+)(?:[\x20\t\r\n\f]*([*^$|!~]?=)[\x20\t\r\n\f]*(?:'((?:\\.|[^\\'])*)'|"((?:\\.|[^\\"])*)"|((?:\\.|[\w-]|[^\x00-\xa0])+))|)[\x20\t\r\n\f]*\])*)|.*)\)|)/,ta=/^(?:\\.|[\w-]|[^\x00-\xa0])+$/,ja={ID:/^#((?:\\.|[\w-]|[^\x00-\xa0])+)/,CLASS:/^\.((?:\\.|[\w-]|[^\x00-\xa0])+)/,TAG:/^((?:\\.|[\w-]|[^\x00-\xa0])+|[*])/,ATTR:/^\[[\x20\t\r\n\f]*((?:\\.|[\w-]|[^\x00-\xa0])+)(?:[\x20\t\r\n\f]*([*^$|!~]?=)[\x20\t\r\n\f]*(?:'((?:\\.|[^\\'])*)'|"((?:\\.|[^\\"])*)"|((?:\\.|[\w-]|[^\x00-\xa0])+))|)[\x20\t\r\n\f]*\]/,
PSEUDO:/^:((?:\\.|[\w-]|[^\x00-\xa0])+)(?:\((('((?:\\.|[^\\'])*)'|"((?:\\.|[^\\"])*)")|((?:\\.|[^\\()[\]]|\[[\x20\t\r\n\f]*((?:\\.|[\w-]|[^\x00-\xa0])+)(?:[\x20\t\r\n\f]*([*^$|!~]?=)[\x20\t\r\n\f]*(?:'((?:\\.|[^\\'])*)'|"((?:\\.|[^\\"])*)"|((?:\\.|[\w-]|[^\x00-\xa0])+))|)[\x20\t\r\n\f]*\])*)|.*)\)|)/,CHILD:/^:(only|first|last|nth|nth-last)-(child|of-type)(?:\([\x20\t\r\n\f]*(even|odd|(([+-]|)(\d*)n|)[\x20\t\r\n\f]*(?:([+-]|)[\x20\t\r\n\f]*(\d+)|))[\x20\t\r\n\f]*\)|)/i,bool:/^(?:checked|selected|async|autofocus|autoplay|controls|defer|disabled|hidden|ismap|loop|multiple|open|readonly|required|scoped)$/i,
needsContext:/^[\x20\t\r\n\f]*[>+~]|:(even|odd|eq|gt|lt|nth|first|last)(?:\([\x20\t\r\n\f]*((?:-\d)?\d*)[\x20\t\r\n\f]*\)|)(?=[^-]|$)/i},Y=/^(?:input|select|textarea|button)$/i,T=/^h\d$/i,ua=/^[^{]+\{\s*\[native \w/,W=/^(?:#([\w-]+)|(\w+)|\.([\w-]+))$/,ma=/[+~]/,La=/'|\\/g,R=/\\([\da-f]{1,6}[\x20\t\r\n\f]?|([\x20\t\r\n\f])|.)/ig,S=function(c,a,b){c="0x"+a-65536;return c!==c||b?a:0>c?String.fromCharCode(c+65536):String.fromCharCode(c>>10|55296,c&1023|56320)},ba=function(){ea()};try{ha.apply(aa=ra.call(X.childNodes),
X.childNodes),aa[X.childNodes.length].nodeType}catch(dc){ha={apply:aa.length?function(c,a){L.apply(c,ra.call(a))}:function(c,a){for(var b=c.length,d=0;c[b++]=a[d++];);c.length=b-1}}}var U=a.support={};var ia=a.isXML=function(c){return(c=c&&(c.ownerDocument||c).documentElement)?"HTML"!==c.nodeName:!1};var ea=a.setDocument=function(c){var a;c=c?c.ownerDocument||c:X;if(c===B||9!==c.nodeType||!c.documentElement)return B;B=c;q=B.documentElement;D=!ia(B);(a=B.defaultView)&&a.top!==a&&(a.addEventListener?
a.addEventListener("unload",ba,!1):a.attachEvent&&a.attachEvent("onunload",ba));U.attributes=g(function(c){c.className="i";return!c.getAttribute("className")});U.getElementsByTagName=g(function(c){c.appendChild(B.createComment(""));return!c.getElementsByTagName("*").length});U.getElementsByClassName=ua.test(B.getElementsByClassName);U.getById=g(function(c){q.appendChild(c).id=H;return!B.getElementsByName||!B.getElementsByName(H).length});U.getById?(O.find.ID=function(c,a){if("undefined"!==typeof a.getElementById&&
D)return(c=a.getElementById(c))?[c]:[]},O.filter.ID=function(c){var a=c.replace(R,S);return function(c){return c.getAttribute("id")===a}}):(delete O.find.ID,O.filter.ID=function(c){var a=c.replace(R,S);return function(c){return(c="undefined"!==typeof c.getAttributeNode&&c.getAttributeNode("id"))&&c.value===a}});O.find.TAG=U.getElementsByTagName?function(c,a){if("undefined"!==typeof a.getElementsByTagName)return a.getElementsByTagName(c);if(U.qsa)return a.querySelectorAll(c)}:function(c,a){var b=[],
d=0;a=a.getElementsByTagName(c);if("*"===c){for(;c=a[d++];)1===c.nodeType&&b.push(c);return b}return a};O.find.CLASS=U.getElementsByClassName&&function(c,a){if("undefined"!==typeof a.getElementsByClassName&&D)return a.getElementsByClassName(c)};G=[];E=[];if(U.qsa=ua.test(B.querySelectorAll))g(function(c){q.appendChild(c).innerHTML="\x3ca id\x3d'"+H+"'\x3e\x3c/a\x3e\x3cselect id\x3d'"+H+"-\r\\' msallowcapture\x3d''\x3e\x3coption selected\x3d''\x3e\x3c/option\x3e\x3c/select\x3e";c.querySelectorAll("[msallowcapture^\x3d'']").length&&
E.push("[*^$]\x3d[\\x20\\t\\r\\n\\f]*(?:''|\"\")");c.querySelectorAll("[selected]").length||E.push("\\[[\\x20\\t\\r\\n\\f]*(?:value|checked|selected|async|autofocus|autoplay|controls|defer|disabled|hidden|ismap|loop|multiple|open|readonly|required|scoped)");c.querySelectorAll("[id~\x3d"+H+"-]").length||E.push("~\x3d");c.querySelectorAll(":checked").length||E.push(":checked");c.querySelectorAll("a#"+H+"+*").length||E.push(".#.+[+~]")}),g(function(c){var a=B.createElement("input");a.setAttribute("type",
"hidden");c.appendChild(a).setAttribute("name","D");c.querySelectorAll("[name\x3dd]").length&&E.push("name[\\x20\\t\\r\\n\\f]*[*^$|!~]?\x3d");c.querySelectorAll(":enabled").length||E.push(":enabled",":disabled");c.querySelectorAll("*,:x");E.push(",.*:")});(U.matchesSelector=ua.test(K=q.matches||q.webkitMatchesSelector||q.mozMatchesSelector||q.oMatchesSelector||q.msMatchesSelector))&&g(function(c){U.disconnectedMatch=K.call(c,"div");K.call(c,"[s!\x3d'']:x");G.push("!\x3d",":((?:\\\\.|[\\w-]|[^\\x00-\\xa0])+)(?:\\((('((?:\\\\.|[^\\\\'])*)'|\"((?:\\\\.|[^\\\\\"])*)\")|((?:\\\\.|[^\\\\()[\\]]|\\[[\\x20\\t\\r\\n\\f]*((?:\\\\.|[\\w-]|[^\\x00-\\xa0])+)(?:[\\x20\\t\\r\\n\\f]*([*^$|!~]?\x3d)[\\x20\\t\\r\\n\\f]*(?:'((?:\\\\.|[^\\\\'])*)'|\"((?:\\\\.|[^\\\\\"])*)\"|((?:\\\\.|[\\w-]|[^\\x00-\\xa0])+))|)[\\x20\\t\\r\\n\\f]*\\])*)|.*)\\)|)")});
E=E.length&&new RegExp(E.join("|"));G=G.length&&new RegExp(G.join("|"));J=(a=ua.test(q.compareDocumentPosition))||ua.test(q.contains)?function(c,a){var b=9===c.nodeType?c.documentElement:c;a=a&&a.parentNode;return c===a||!!(a&&1===a.nodeType&&(b.contains?b.contains(a):c.compareDocumentPosition&&c.compareDocumentPosition(a)&16))}:function(c,a){if(a)for(;a=a.parentNode;)if(a===c)return!0;return!1};da=a?function(c,a){if(c===a)return y=!0,0;var b=!c.compareDocumentPosition-!a.compareDocumentPosition;
if(b)return b;b=(c.ownerDocument||c)===(a.ownerDocument||a)?c.compareDocumentPosition(a):1;return b&1||!U.sortDetached&&a.compareDocumentPosition(c)===b?c===B||c.ownerDocument===X&&J(X,c)?-1:a===B||a.ownerDocument===X&&J(X,a)?1:C?N(C,c)-N(C,a):0:b&4?-1:1}:function(c,a){if(c===a)return y=!0,0;var b=0,d=c.parentNode,g=a.parentNode,p=[c],e=[a];if(!d||!g)return c===B?-1:a===B?1:d?-1:g?1:C?N(C,c)-N(C,a):0;if(d===g)return h(c,a);for(;c=c.parentNode;)p.unshift(c);for(c=a;c=c.parentNode;)e.unshift(c);for(;p[b]===
e[b];)b++;return b?h(p[b],e[b]):p[b]===X?-1:e[b]===X?1:0};return B};a.matches=function(c,b){return a(c,null,null,b)};a.matchesSelector=function(c,b){(c.ownerDocument||c)!==B&&ea(c);b=b.replace(Da,"\x3d'$1']");if(!(!U.matchesSelector||!D||ca[b+" "]||G&&G.test(b)||E&&E.test(b)))try{var d=K.call(c,b);if(d||U.disconnectedMatch||c.document&&11!==c.document.nodeType)return d}catch(fc){}return 0<a(b,B,null,[c]).length};a.contains=function(c,a){(c.ownerDocument||c)!==B&&ea(c);return J(c,a)};a.attr=function(c,
a){(c.ownerDocument||c)!==B&&ea(c);var b=O.attrHandle[a.toLowerCase()];b=b&&V.call(O.attrHandle,a.toLowerCase())?b(c,a,!D):n;return b!==n?b:U.attributes||!D?c.getAttribute(a):(b=c.getAttributeNode(a))&&b.specified?b.value:null};a.error=function(c){throw Error("Syntax error, unrecognized expression: "+c);};a.uniqueSort=function(c){var a,b=[],d=0,g=0;y=!U.detectDuplicates;C=!U.sortStable&&c.slice(0);c.sort(da);if(y){for(;a=c[g++];)a===c[g]&&(d=b.push(g));for(;d--;)c.splice(b[d],1)}C=null;return c};
var la=a.getText=function(c){var a="",b=0;var d=c.nodeType;if(!d)for(;d=c[b++];)a+=la(d);else if(1===d||9===d||11===d){if("string"===typeof c.textContent)return c.textContent;for(c=c.firstChild;c;c=c.nextSibling)a+=la(c)}else if(3===d||4===d)return c.nodeValue;return a};var O=a.selectors={cacheLength:50,createPseudo:d,match:ja,attrHandle:{},find:{},relative:{"\x3e":{dir:"parentNode",first:!0}," ":{dir:"parentNode"},"+":{dir:"previousSibling",first:!0},"~":{dir:"previousSibling"}},preFilter:{ATTR:function(c){c[1]=
c[1].replace(R,S);c[3]=(c[3]||c[4]||c[5]||"").replace(R,S);"~\x3d"===c[2]&&(c[3]=" "+c[3]+" ");return c.slice(0,4)},CHILD:function(c){c[1]=c[1].toLowerCase();"nth"===c[1].slice(0,3)?(c[3]||a.error(c[0]),c[4]=+(c[4]?c[5]+(c[6]||1):2*("even"===c[3]||"odd"===c[3])),c[5]=+(c[7]+c[8]||"odd"===c[3])):c[3]&&a.error(c[0]);return c},PSEUDO:function(c){var a,b=!c[6]&&c[2];if(ja.CHILD.test(c[0]))return null;c[3]?c[2]=c[4]||c[5]||"":b&&oa.test(b)&&(a=fa(b,!0))&&(a=b.indexOf(")",b.length-a)-b.length)&&(c[0]=c[0].slice(0,
a),c[2]=b.slice(0,a));return c.slice(0,3)}},filter:{TAG:function(c){var a=c.replace(R,S).toLowerCase();return"*"===c?function(){return!0}:function(c){return c.nodeName&&c.nodeName.toLowerCase()===a}},CLASS:function(c){var a=I[c+" "];return a||(a=new RegExp("(^|[\\x20\\t\\r\\n\\f])"+c+"([\\x20\\t\\r\\n\\f]|$)"),I(c,function(c){return a.test("string"===typeof c.className&&c.className||"undefined"!==typeof c.getAttribute&&c.getAttribute("class")||"")}))},ATTR:function(c,b,d){return function(g){g=a.attr(g,
c);if(null==g)return"!\x3d"===b;if(!b)return!0;g+="";return"\x3d"===b?g===d:"!\x3d"===b?g!==d:"^\x3d"===b?d&&0===g.indexOf(d):"*\x3d"===b?d&&-1<g.indexOf(d):"$\x3d"===b?d&&g.slice(-d.length)===d:"~\x3d"===b?-1<(" "+g.replace(sa," ")+" ").indexOf(d):"|\x3d"===b?g===d||g.slice(0,d.length+1)===d+"-":!1}},CHILD:function(c,a,b,d,g){var p="nth"!==c.slice(0,3),h="last"!==c.slice(-4),e="of-type"===a;return 1===d&&0===g?function(c){return!!c.parentNode}:function(a,b,m){var l,f;b=p!==h?"nextSibling":"previousSibling";
var v=a.parentNode,k=e&&a.nodeName.toLowerCase();m=!m&&!e;var F=!1;if(v){if(p){for(;b;){for(l=a;l=l[b];)if(e?l.nodeName.toLowerCase()===k:1===l.nodeType)return!1;var A=b="only"===c&&!A&&"nextSibling"}return!0}A=[h?v.firstChild:v.lastChild];if(h&&m){l=v;var x=l[H]||(l[H]={});x=x[l.uniqueID]||(x[l.uniqueID]={});F=x[c]||[];F=(f=F[0]===Q&&F[1])&&F[2];for(l=f&&v.childNodes[f];l=++f&&l&&l[b]||(F=f=0)||A.pop();)if(1===l.nodeType&&++F&&l===a){x[c]=[Q,f,F];break}}else if(m&&(l=a,x=l[H]||(l[H]={}),x=x[l.uniqueID]||
(x[l.uniqueID]={}),F=x[c]||[],F=f=F[0]===Q&&F[1]),!1===F)for(;(l=++f&&l&&l[b]||(F=f=0)||A.pop())&&((e?l.nodeName.toLowerCase()!==k:1!==l.nodeType)||!++F||(m&&(x=l[H]||(l[H]={}),x=x[l.uniqueID]||(x[l.uniqueID]={}),x[c]=[Q,F]),l!==a)););F-=g;return F===d||0===F%d&&0<=F/d}}},PSEUDO:function(c,b){var g=O.pseudos[c]||O.setFilters[c.toLowerCase()]||a.error("unsupported pseudo: "+c);if(g[H])return g(b);if(1<g.length){var p=[c,c,"",b];return O.setFilters.hasOwnProperty(c.toLowerCase())?d(function(c,a){for(var d,
p=g(c,b),h=p.length;h--;)d=N(c,p[h]),c[d]=!(a[d]=p[h])}):function(c){return g(c,0,p)}}return g}},pseudos:{not:d(function(c){var a=[],b=[],g=ka(c.replace(Z,"$1"));return g[H]?d(function(c,a,b,d){d=g(c,null,d,[]);for(var p=c.length;p--;)if(b=d[p])c[p]=!(a[p]=b)}):function(c,d,p){a[0]=c;g(a,null,p,b);a[0]=null;return!b.pop()}}),has:d(function(c){return function(b){return 0<a(c,b).length}}),contains:d(function(c){c=c.replace(R,S);return function(a){return-1<(a.textContent||a.innerText||la(a)).indexOf(c)}}),
lang:d(function(c){ta.test(c||"")||a.error("unsupported lang: "+c);c=c.replace(R,S).toLowerCase();return function(a){var b;do if(b=D?a.lang:a.getAttribute("xml:lang")||a.getAttribute("lang"))return b=b.toLowerCase(),b===c||0===b.indexOf(c+"-");while((a=a.parentNode)&&1===a.nodeType);return!1}}),target:function(a){var b=c.location&&c.location.hash;return b&&b.slice(1)===a.id},root:function(c){return c===q},focus:function(c){return c===B.activeElement&&(!B.hasFocus||B.hasFocus())&&!!(c.type||c.href||
~c.tabIndex)},enabled:function(c){return!1===c.disabled},disabled:function(c){return!0===c.disabled},checked:function(c){var a=c.nodeName.toLowerCase();return"input"===a&&!!c.checked||"option"===a&&!!c.selected},selected:function(c){c.parentNode&&c.parentNode.selectedIndex;return!0===c.selected},empty:function(c){for(c=c.firstChild;c;c=c.nextSibling)if(6>c.nodeType)return!1;return!0},parent:function(c){return!O.pseudos.empty(c)},header:function(c){return T.test(c.nodeName)},input:function(c){return Y.test(c.nodeName)},
button:function(c){var a=c.nodeName.toLowerCase();return"input"===a&&"button"===c.type||"button"===a},text:function(c){var a;return"input"===c.nodeName.toLowerCase()&&"text"===c.type&&(null==(a=c.getAttribute("type"))||"text"===a.toLowerCase())},first:l(function(){return[0]}),last:l(function(c,a){return[a-1]}),eq:l(function(c,a,b){return[0>b?b+a:b]}),even:l(function(c,a){for(var b=0;b<a;b+=2)c.push(b);return c}),odd:l(function(c,a){for(var b=1;b<a;b+=2)c.push(b);return c}),lt:l(function(c,a,b){for(a=
0>b?b+a:b;0<=--a;)c.push(a);return c}),gt:l(function(c,a,b){for(b=0>b?b+a:b;++b<a;)c.push(b);return c})}};O.pseudos.nth=O.pseudos.eq;for(z in{radio:!0,checkbox:!0,file:!0,password:!0,image:!0})O.pseudos[z]=e(z);for(z in{submit:!0,reset:!0})O.pseudos[z]=m(z);v.prototype=O.filters=O.pseudos;O.setFilters=new v;var fa=a.tokenize=function(c,b){var d,g,p,h,e;if(h=na[c+" "])return b?0:h.slice(0);h=c;var m=[];for(e=O.preFilter;h;){if(!l||(d=P.exec(h)))d&&(h=h.slice(d[0].length)||h),m.push(g=[]);var l=!1;
if(d=xa.exec(h))l=d.shift(),g.push({value:l,type:d[0].replace(Z," ")}),h=h.slice(l.length);for(p in O.filter)!(d=ja[p].exec(h))||e[p]&&!(d=e[p](d))||(l=d.shift(),g.push({value:l,type:p,matches:d}),h=h.slice(l.length));if(!l)break}return b?h.length:h?a.error(c):na(c,m).slice(0)};var ka=a.compile=function(c,a){var b,d=[],g=[],p=ca[c+" "];if(!p){a||(a=fa(c));for(b=a.length;b--;)p=w(a[b]),p[H]?d.push(p):g.push(p);p=ca(c,r(g,d));p.selector=c}return p};var pa=a.select=function(c,a,b,d){var g,p,h,e="function"===
typeof c&&c,m=!d&&fa(c=e.selector||c);b=b||[];if(1===m.length){var l=m[0]=m[0].slice(0);if(2<l.length&&"ID"===(p=l[0]).type&&U.getById&&9===a.nodeType&&D&&O.relative[l[1].type]){a=(O.find.ID(p.matches[0].replace(R,S),a)||[])[0];if(!a)return b;e&&(a=a.parentNode);c=c.slice(l.shift().value.length)}for(g=ja.needsContext.test(c)?0:l.length;g--;){p=l[g];if(O.relative[h=p.type])break;if(h=O.find[h])if(d=h(p.matches[0].replace(R,S),ma.test(l[0].type)&&f(a.parentNode)||a)){l.splice(g,1);c=d.length&&k(l);
if(!c)return ha.apply(b,d),b;break}}}(e||ka(c,m))(d,a,!D,b,!a||ma.test(c)&&f(a.parentNode)||a);return b};U.sortStable=H.split("").sort(da).join("")===H;U.detectDuplicates=!!y;ea();U.sortDetached=g(function(c){return c.compareDocumentPosition(B.createElement("div"))&1});g(function(c){c.innerHTML="\x3ca href\x3d'#'\x3e\x3c/a\x3e";return"#"===c.firstChild.getAttribute("href")})||p("type|href|height|width",function(c,a,b){if(!b)return c.getAttribute(a,"type"===a.toLowerCase()?1:2)});U.attributes&&g(function(c){c.innerHTML=
"\x3cinput/\x3e";c.firstChild.setAttribute("value","");return""===c.firstChild.getAttribute("value")})||p("value",function(c,a,b){if(!b&&"input"===c.nodeName.toLowerCase())return c.defaultValue});g(function(c){return null==c.getAttribute("disabled")})||p("checked|selected|async|autofocus|autoplay|controls|defer|disabled|hidden|ismap|loop|multiple|open|readonly|required|scoped",function(c,a,b){var d;if(!b)return!0===c[a]?a.toLowerCase():(d=c.getAttributeNode(a))&&d.specified?d.value:null});return a}(f);
t.find=ea;t.expr=ea.selectors;t.expr[":"]=t.expr.pseudos;t.uniqueSort=t.unique=ea.uniqueSort;t.text=ea.getText;t.isXMLDoc=ea.isXML;t.contains=ea.contains;var la=function(c,a,b){for(var d=[],g=b!==n;(c=c[a])&&9!==c.nodeType;)if(1===c.nodeType){if(g&&t(c).is(b))break;d.push(c)}return d},$a=function(c,a){for(var b=[];c;c=c.nextSibling)1===c.nodeType&&c!==a&&b.push(c);return b},ab=t.expr.match.needsContext,bb=/^<([\w-]+)\s*\/?>(?:<\/\1>|)$/,nb=/^.[^:#\[\.,]*$/;t.filter=function(c,a,b){var d=a[0];b&&(c=
":not("+c+")");return 1===a.length&&1===d.nodeType?t.find.matchesSelector(d,c)?[d]:[]:t.find.matches(c,t.grep(a,function(c){return 1===c.nodeType}))};t.fn.extend({find:function(c){var a,b=this.length,d=[],g=this;if("string"!==typeof c)return this.pushStack(t(c).filter(function(){for(a=0;a<b;a++)if(t.contains(g[a],this))return!0}));for(a=0;a<b;a++)t.find(c,g[a],d);d=this.pushStack(1<b?t.unique(d):d);d.selector=this.selector?this.selector+" "+c:c;return d},filter:function(c){return this.pushStack(b(this,
c||[],!1))},not:function(c){return this.pushStack(b(this,c||[],!0))},is:function(c){return!!b(this,"string"===typeof c&&ab.test(c)?t(c):c||[],!1).length}});var Ab=/^(?:\s*(<[\w\W]+>)[^>]*|#([\w-]*))$/;(t.fn.init=function(c,a,b){if(!c)return this;b=b||Bb;if("string"===typeof c){var d="\x3c"===c[0]&&"\x3e"===c[c.length-1]&&3<=c.length?[null,c,null]:Ab.exec(c);if(!d||!d[1]&&a)return!a||a.jquery?(a||b).find(c):this.constructor(a).find(c);if(d[1]){if(a=a instanceof t?a[0]:a,t.merge(this,t.parseHTML(d[1],
a&&a.nodeType?a.ownerDocument||a:I,!0)),bb.test(d[1])&&t.isPlainObject(a))for(d in a)if(t.isFunction(this[d]))this[d](a[d]);else this.attr(d,a[d])}else(a=I.getElementById(d[2]))&&a.parentNode&&(this.length=1,this[0]=a),this.context=I,this.selector=c;return this}if(c.nodeType)return this.context=this[0]=c,this.length=1,this;if(t.isFunction(c))return b.ready!==n?b.ready(c):c(t);c.selector!==n&&(this.selector=c.selector,this.context=c.context);return t.makeArray(c,this)}).prototype=t.fn;var Bb=t(I);
var Cb=/^(?:parents|prev(?:Until|All))/,Db={children:!0,contents:!0,next:!0,prev:!0};t.fn.extend({has:function(c){var a=t(c,this),b=a.length;return this.filter(function(){for(var c=0;c<b;c++)if(t.contains(this,a[c]))return!0})},closest:function(c,a){for(var b,d=0,g=this.length,p=[],h=ab.test(c)||"string"!==typeof c?t(c,a||this.context):0;d<g;d++)for(b=this[d];b&&b!==a;b=b.parentNode)if(11>b.nodeType&&(h?-1<h.index(b):1===b.nodeType&&t.find.matchesSelector(b,c))){p.push(b);break}return this.pushStack(1<
p.length?t.uniqueSort(p):p)},index:function(c){return c?"string"===typeof c?ha.call(t(c),this[0]):ha.call(this,c.jquery?c[0]:c):this[0]&&this[0].parentNode?this.first().prevAll().length:-1},add:function(c,a){return this.pushStack(t.uniqueSort(t.merge(this.get(),t(c,a))))},addBack:function(c){return this.add(null==c?this.prevObject:this.prevObject.filter(c))}});t.each({parent:function(c){return(c=c.parentNode)&&11!==c.nodeType?c:null},parents:function(c){return la(c,"parentNode")},parentsUntil:function(c,
a,b){return la(c,"parentNode",b)},next:function(c){return d(c,"nextSibling")},prev:function(c){return d(c,"previousSibling")},nextAll:function(c){return la(c,"nextSibling")},prevAll:function(c){return la(c,"previousSibling")},nextUntil:function(c,a,b){return la(c,"nextSibling",b)},prevUntil:function(c,a,b){return la(c,"previousSibling",b)},siblings:function(c){return $a((c.parentNode||{}).firstChild,c)},children:function(c){return $a(c.firstChild)},contents:function(c){return c.contentDocument||t.merge([],
c.childNodes)}},function(c,a){t.fn[c]=function(b,d){var g=t.map(this,a,b);"Until"!==c.slice(-5)&&(d=b);d&&"string"===typeof d&&(g=t.filter(d,g));1<this.length&&(Db[c]||t.uniqueSort(g),Cb.test(c)&&g.reverse());return this.pushStack(g)}});var ia=/\S+/g;t.Callbacks=function(c){c="string"===typeof c?h(c):t.extend({},c);var a,b,d,g,p=[],e=[],m=-1,l=function(){g=c.once;for(d=a=!0;e.length;m=-1)for(b=e.shift();++m<p.length;)!1===p[m].apply(b[0],b[1])&&c.stopOnFalse&&(m=p.length,b=!1);c.memory||(b=!1);a=
!1;g&&(p=b?[]:"")},f={add:function(){p&&(b&&!a&&(m=p.length-1,e.push(b)),function tb(a){t.each(a,function(a,b){t.isFunction(b)?c.unique&&f.has(b)||p.push(b):b&&b.length&&"string"!==t.type(b)&&tb(b)})}(arguments),b&&!a&&l());return this},remove:function(){t.each(arguments,function(c,a){for(var b;-1<(b=t.inArray(a,p,b));)p.splice(b,1),b<=m&&m--});return this},has:function(c){return c?-1<t.inArray(c,p):0<p.length},empty:function(){p&&(p=[]);return this},disable:function(){g=e=[];p=b="";return this},
disabled:function(){return!p},lock:function(){g=e=[];b||(p=b="");return this},locked:function(){return!!g},fireWith:function(c,b){g||(b=b||[],b=[c,b.slice?b.slice():b],e.push(b),a||l());return this},fire:function(){f.fireWith(this,arguments);return this},fired:function(){return!!d}};return f};t.extend({Deferred:function(c){var a=[["resolve","done",t.Callbacks("once memory"),"resolved"],["reject","fail",t.Callbacks("once memory"),"rejected"],["notify","progress",t.Callbacks("memory")]],b="pending",
d={state:function(){return b},always:function(){g.done(arguments).fail(arguments);return this},then:function(){var c=arguments;return t.Deferred(function(b){t.each(a,function(a,p){var h=t.isFunction(c[a])&&c[a];g[p[1]](function(){var c=h&&h.apply(this,arguments);if(c&&t.isFunction(c.promise))c.promise().progress(b.notify).done(b.resolve).fail(b.reject);else b[p[0]+"With"](this===d?b.promise():this,h?[c]:arguments)})});c=null}).promise()},promise:function(c){return null!=c?t.extend(c,d):d}},g={};d.pipe=
d.then;t.each(a,function(c,p){var h=p[2],e=p[3];d[p[1]]=h.add;e&&h.add(function(){b=e},a[c^1][2].disable,a[2][2].lock);g[p[0]]=function(){g[p[0]+"With"](this===g?d:this,arguments);return this};g[p[0]+"With"]=h.fireWith});d.promise(g);c&&c.call(g,g);return g},when:function(c){var a=0,b=ja.call(arguments),d=b.length,g=1!==d||c&&t.isFunction(c.promise)?d:0,p=1===g?c:t.Deferred(),h=function(c,a,b){return function(d){a[c]=this;b[c]=1<arguments.length?ja.call(arguments):d;b===m?p.notifyWith(a,b):--g||p.resolveWith(a,
b)}},e;if(1<d){var m=Array(d);var l=Array(d);for(e=Array(d);a<d;a++)b[a]&&t.isFunction(b[a].promise)?b[a].promise().progress(h(a,l,m)).done(h(a,e,b)).fail(p.reject):--g}g||p.resolveWith(e,b);return p.promise()}});var Ga;t.fn.ready=function(c){t.ready.promise().done(c);return this};t.extend({isReady:!1,readyWait:1,holdReady:function(c){c?t.readyWait++:t.ready(!0)},ready:function(c){(!0===c?--t.readyWait:t.isReady)||(t.isReady=!0,!0!==c&&0<--t.readyWait||(Ga.resolveWith(I,[t]),t.fn.triggerHandler&&
(t(I).triggerHandler("ready"),t(I).off("ready"))))}});t.ready.promise=function(c){Ga||(Ga=t.Deferred(),"complete"===I.readyState||"loading"!==I.readyState&&!I.documentElement.doScroll?f.setTimeout(t.ready):(I.addEventListener("DOMContentLoaded",a),f.addEventListener("load",a)));return Ga.promise(c)};t.ready.promise();var fa=function(c,a,b,d,g,p,h){var e=0,m=c.length,l=null==b;if("object"===t.type(b))for(e in g=!0,b)fa(c,a,e,b[e],!0,p,h);else if(d!==n&&(g=!0,t.isFunction(d)||(h=!0),l&&(h?(a.call(c,
d),a=null):(l=a,a=function(c,a,b){return l.call(t(c),b)})),a))for(;e<m;e++)a(c[e],b,h?d:d.call(c[e],e,a(c[e],b)));return g?c:l?a.call(c):m?a(c[0],b):p},ya=function(c){return 1===c.nodeType||9===c.nodeType||!+c.nodeType};g.uid=1;g.prototype={register:function(c,a){a=a||{};c.nodeType?c[this.expando]=a:Object.defineProperty(c,this.expando,{value:a,writable:!0,configurable:!0});return c[this.expando]},cache:function(c){if(!ya(c))return{};var a=c[this.expando];a||(a={},ya(c)&&(c.nodeType?c[this.expando]=
a:Object.defineProperty(c,this.expando,{value:a,configurable:!0})));return a},set:function(c,a,b){var d;c=this.cache(c);if("string"===typeof a)c[a]=b;else for(d in a)c[d]=a[d];return c},get:function(c,a){return a===n?this.cache(c):c[this.expando]&&c[this.expando][a]},access:function(c,a,b){if(a===n||a&&"string"===typeof a&&b===n)return b=this.get(c,a),b!==n?b:this.get(c,t.camelCase(a));this.set(c,a,b);return b!==n?b:a},remove:function(c,a){var b=c[this.expando];if(b!==n){if(a===n)this.register(c);
else{if(t.isArray(a))var d=a.concat(a.map(t.camelCase));else{var g=t.camelCase(a);a in b?d=[a,g]:(d=g,d=d in b?[d]:d.match(ia)||[])}for(g=d.length;g--;)delete b[d[g]]}if(a===n||t.isEmptyObject(b))c.nodeType?c[this.expando]=n:delete c[this.expando]}},hasData:function(c){c=c[this.expando];return c!==n&&!t.isEmptyObject(c)}};var L=new g,W=new g,ob=/^(?:\{[\w\W]*\}|\[[\w\W]*\])$/,Ta=/[A-Z]/g;t.extend({hasData:function(c){return W.hasData(c)||L.hasData(c)},data:function(c,a,b){return W.access(c,a,b)},
removeData:function(c,a){W.remove(c,a)},_data:function(c,a,b){return L.access(c,a,b)},_removeData:function(c,a){L.remove(c,a)}});t.fn.extend({data:function(c,a){var b,d=this[0],g=d&&d.attributes;if(c===n){if(this.length){var p=W.get(d);if(1===d.nodeType&&!L.get(d,"hasDataAttrs")){for(b=g.length;b--;)if(g[b]){var h=g[b].name;0===h.indexOf("data-")&&(h=t.camelCase(h.slice(5)),l(d,h,p[h]))}L.set(d,"hasDataAttrs",!0)}}return p}return"object"===typeof c?this.each(function(){W.set(this,c)}):fa(this,function(a){if(d&&
a===n){var b=W.get(d,c)||W.get(d,c.replace(Ta,"-$\x26").toLowerCase());if(b!==n)return b;var g=t.camelCase(c);b=W.get(d,g);if(b!==n)return b;b=l(d,g,n);if(b!==n)return b}else g=t.camelCase(c),this.each(function(){var b=W.get(this,g);W.set(this,g,a);-1<c.indexOf("-")&&b!==n&&W.set(this,c,a)})},null,a,1<arguments.length,null,!0)},removeData:function(c){return this.each(function(){W.remove(this,c)})}});t.extend({queue:function(c,a,b){if(c){a=(a||"fx")+"queue";var d=L.get(c,a);b&&(!d||t.isArray(b)?d=
L.access(c,a,t.makeArray(b)):d.push(b));return d||[]}},dequeue:function(c,a){a=a||"fx";var b=t.queue(c,a),d=b.length,g=b.shift(),p=t._queueHooks(c,a),h=function(){t.dequeue(c,a)};"inprogress"===g&&(g=b.shift(),d--);g&&("fx"===a&&b.unshift("inprogress"),delete p.stop,g.call(c,h,p));!d&&p&&p.empty.fire()},_queueHooks:function(c,a){var b=a+"queueHooks";return L.get(c,b)||L.access(c,b,{empty:t.Callbacks("once memory").add(function(){L.remove(c,[a+"queue",b])})})}});t.fn.extend({queue:function(c,a){var b=
2;"string"!==typeof c&&(a=c,c="fx",b--);return arguments.length<b?t.queue(this[0],c):a===n?this:this.each(function(){var b=t.queue(this,c,a);t._queueHooks(this,c);"fx"===c&&"inprogress"!==b[0]&&t.dequeue(this,c)})},dequeue:function(c){return this.each(function(){t.dequeue(this,c)})},clearQueue:function(c){return this.queue(c||"fx",[])},promise:function(c,a){var b,d=1,g=t.Deferred(),p=this,h=this.length,e=function(){--d||g.resolveWith(p,[p])};"string"!==typeof c&&(a=c,c=n);for(c=c||"fx";h--;)(b=L.get(p[h],
c+"queueHooks"))&&b.empty&&(d++,b.empty.add(e));e();return g.promise(a)}});var cb=/[+-]?(?:\d*\.|)\d+(?:[eE][+-]?\d+|)/.source,va=new RegExp("^(?:([+-])\x3d|)("+cb+")([a-z%]*)$","i"),ka=["Top","Right","Bottom","Left"],wa=function(c,a){c=a||c;return"none"===t.css(c,"display")||!t.contains(c.ownerDocument,c)},db=/^(?:checkbox|radio)$/i,Ua=/<([\w:-]+)/,Va=/^$|\/(?:java|ecma)script/i,ba={option:[1,"\x3cselect multiple\x3d'multiple'\x3e","\x3c/select\x3e"],thead:[1,"\x3ctable\x3e","\x3c/table\x3e"],col:[2,
"\x3ctable\x3e\x3ccolgroup\x3e","\x3c/colgroup\x3e\x3c/table\x3e"],tr:[2,"\x3ctable\x3e\x3ctbody\x3e","\x3c/tbody\x3e\x3c/table\x3e"],td:[3,"\x3ctable\x3e\x3ctbody\x3e\x3ctr\x3e","\x3c/tr\x3e\x3c/tbody\x3e\x3c/table\x3e"],_default:[0,"",""]};ba.optgroup=ba.option;ba.tbody=ba.tfoot=ba.colgroup=ba.caption=ba.thead;ba.th=ba.td;var qb=/<|&#?\w+;/;(function(){var c=I.createDocumentFragment().appendChild(I.createElement("div")),a=I.createElement("input");a.setAttribute("type","radio");a.setAttribute("checked",
"checked");a.setAttribute("name","t");c.appendChild(a);P.checkClone=c.cloneNode(!0).cloneNode(!0).lastChild.checked;c.innerHTML="\x3ctextarea\x3ex\x3c/textarea\x3e";P.noCloneChecked=!!c.cloneNode(!0).lastChild.defaultValue})();var Eb=/^key/,Fb=/^(?:mouse|pointer|contextmenu|drag|drop)|click/,eb=/^([^.]*)(?:\.(.+)|)/;t.event={global:{},add:function(c,a,b,d,g){var p,h,e,m,l;if(e=L.get(c)){if(b.handler){var f=b;b=f.handler;g=f.selector}b.guid||(b.guid=t.guid++);(h=e.events)||(h=e.events={});(p=e.handle)||
(p=e.handle=function(a){return"undefined"!==typeof t&&t.event.triggered!==a.type?t.event.dispatch.apply(c,arguments):n});a=(a||"").match(ia)||[""];for(e=a.length;e--;){var v=eb.exec(a[e])||[];var k=m=v[1];var A=(v[2]||"").split(".").sort();k&&(v=t.event.special[k]||{},k=(g?v.delegateType:v.bindType)||k,v=t.event.special[k]||{},m=t.extend({type:k,origType:m,data:d,handler:b,guid:b.guid,selector:g,needsContext:g&&t.expr.match.needsContext.test(g),namespace:A.join(".")},f),(l=h[k])||(l=h[k]=[],l.delegateCount=
0,v.setup&&!1!==v.setup.call(c,d,A,p)||c.addEventListener&&c.addEventListener(k,p)),v.add&&(v.add.call(c,m),m.handler.guid||(m.handler.guid=b.guid)),g?l.splice(l.delegateCount++,0,m):l.push(m),t.event.global[k]=!0)}}},remove:function(c,a,b,d,g){var p,h,e,m,l,f=L.hasData(c)&&L.get(c);if(f&&(e=f.events)){a=(a||"").match(ia)||[""];for(m=a.length;m--;){var v=eb.exec(a[m])||[];var k=l=v[1];var A=(v[2]||"").split(".").sort();if(k){var x=t.event.special[k]||{};k=(d?x.delegateType:x.bindType)||k;var u=e[k]||
[];v=v[2]&&new RegExp("(^|\\.)"+A.join("\\.(?:.*\\.|)")+"(\\.|$)");for(h=p=u.length;p--;){var w=u[p];!g&&l!==w.origType||b&&b.guid!==w.guid||v&&!v.test(w.namespace)||d&&d!==w.selector&&("**"!==d||!w.selector)||(u.splice(p,1),w.selector&&u.delegateCount--,x.remove&&x.remove.call(c,w))}h&&!u.length&&(x.teardown&&!1!==x.teardown.call(c,A,f.handle)||t.removeEvent(c,k,f.handle),delete e[k])}else for(k in e)t.event.remove(c,k+a[m],b,d,!0)}t.isEmptyObject(e)&&L.remove(c,"handle events")}},dispatch:function(c){c=
t.event.fix(c);var a,b,d,g=ja.call(arguments);var p=(L.get(this,"events")||{})[c.type]||[];var h=t.event.special[c.type]||{};g[0]=c;c.delegateTarget=this;if(!h.preDispatch||!1!==h.preDispatch.call(this,c)){var e=t.event.handlers.call(this,c,p);for(p=0;(d=e[p++])&&!c.isPropagationStopped();)for(c.currentTarget=d.elem,a=0;(b=d.handlers[a++])&&!c.isImmediatePropagationStopped();)if(!c.rnamespace||c.rnamespace.test(b.namespace))c.handleObj=b,c.data=b.data,b=((t.event.special[b.origType]||{}).handle||
b.handler).apply(d.elem,g),b!==n&&!1===(c.result=b)&&(c.preventDefault(),c.stopPropagation());h.postDispatch&&h.postDispatch.call(this,c);return c.result}},handlers:function(c,a){var b,d=[],g=a.delegateCount,p=c.target;if(g&&p.nodeType&&("click"!==c.type||isNaN(c.button)||1>c.button))for(;p!==this;p=p.parentNode||this)if(1===p.nodeType&&(!0!==p.disabled||"click"!==c.type)){var h=[];for(b=0;b<g;b++){var e=a[b];var m=e.selector+" ";h[m]===n&&(h[m]=e.needsContext?-1<t(m,this).index(p):t.find(m,this,
null,[p]).length);h[m]&&h.push(e)}h.length&&d.push({elem:p,handlers:h})}g<a.length&&d.push({elem:this,handlers:a.slice(g)});return d},props:"altKey bubbles cancelable ctrlKey currentTarget detail eventPhase metaKey relatedTarget shiftKey target timeStamp view which".split(" "),fixHooks:{},keyHooks:{props:["char","charCode","key","keyCode"],filter:function(c,a){null==c.which&&(c.which=null!=a.charCode?a.charCode:a.keyCode);return c}},mouseHooks:{props:"button buttons clientX clientY offsetX offsetY pageX pageY screenX screenY toElement".split(" "),
filter:function(c,a){var b=a.button;if(null==c.pageX&&null!=a.clientX){var d=c.target.ownerDocument||I;var g=d.documentElement;d=d.body;c.pageX=a.clientX+(g&&g.scrollLeft||d&&d.scrollLeft||0)-(g&&g.clientLeft||d&&d.clientLeft||0);c.pageY=a.clientY+(g&&g.scrollTop||d&&d.scrollTop||0)-(g&&g.clientTop||d&&d.clientTop||0)}c.which||b===n||(c.which=b&1?1:b&2?3:b&4?2:0);return c}},fix:function(c){if(c[t.expando])return c;var a=c.type;var b=c,d=this.fixHooks[a];d||(this.fixHooks[a]=d=Fb.test(a)?this.mouseHooks:
Eb.test(a)?this.keyHooks:{});var g=d.props?this.props.concat(d.props):this.props;c=new t.Event(b);for(a=g.length;a--;){var p=g[a];c[p]=b[p]}c.target||(c.target=I);3===c.target.nodeType&&(c.target=c.target.parentNode);return d.filter?d.filter(c,b):c},special:{load:{noBubble:!0},focus:{trigger:function(){if(this!==y()&&this.focus)return this.focus(),!1},delegateType:"focusin"},blur:{trigger:function(){if(this===y()&&this.blur)return this.blur(),!1},delegateType:"focusout"},click:{trigger:function(){if("checkbox"===
this.type&&this.click&&t.nodeName(this,"input"))return this.click(),!1},_default:function(c){return t.nodeName(c.target,"a")}},beforeunload:{postDispatch:function(c){c.result!==n&&c.originalEvent&&(c.originalEvent.returnValue=c.result)}}}};t.removeEvent=function(c,a,b){c.removeEventListener&&c.removeEventListener(a,b)};t.Event=function(c,a){if(!(this instanceof t.Event))return new t.Event(c,a);c&&c.type?(this.originalEvent=c,this.type=c.type,this.isDefaultPrevented=c.defaultPrevented||c.defaultPrevented===
n&&!1===c.returnValue?w:r):this.type=c;a&&t.extend(this,a);this.timeStamp=c&&c.timeStamp||t.now();this[t.expando]=!0};t.Event.prototype={constructor:t.Event,isDefaultPrevented:r,isPropagationStopped:r,isImmediatePropagationStopped:r,isSimulated:!1,preventDefault:function(){var c=this.originalEvent;this.isDefaultPrevented=w;c&&!this.isSimulated&&c.preventDefault()},stopPropagation:function(){var c=this.originalEvent;this.isPropagationStopped=w;c&&!this.isSimulated&&c.stopPropagation()},stopImmediatePropagation:function(){var c=
this.originalEvent;this.isImmediatePropagationStopped=w;c&&!this.isSimulated&&c.stopImmediatePropagation();this.stopPropagation()}};t.each({mouseenter:"mouseover",mouseleave:"mouseout",pointerenter:"pointerover",pointerleave:"pointerout"},function(c,a){t.event.special[c]={delegateType:a,bindType:a,handle:function(c){var b=c.relatedTarget,d=c.handleObj;if(!b||b!==this&&!t.contains(this,b)){c.type=d.origType;var g=d.handler.apply(this,arguments);c.type=a}return g}}});t.fn.extend({on:function(a,b,d,
g){return c(this,a,b,d,g)},one:function(a,b,d,g){return c(this,a,b,d,g,1)},off:function(c,a,b){if(c&&c.preventDefault&&c.handleObj){var d=c.handleObj;t(c.delegateTarget).off(d.namespace?d.origType+"."+d.namespace:d.origType,d.selector,d.handler);return this}if("object"===typeof c){for(d in c)this.off(d,a,c[d]);return this}if(!1===a||"function"===typeof a)b=a,a=n;!1===b&&(b=r);return this.each(function(){t.event.remove(this,c,b,a)})}});var Gb=/<(?!area|br|col|embed|hr|img|input|link|meta|param)(([\w:-]+)[^>]*)\/>/gi,
Hb=/<script|<style|<link/i,sb=/checked\s*(?:[^=]|=\s*.checked.)/i,rb=/^true\/(.*)/,ub=/^\s*<!(?:\[CDATA\[|--)|(?:\]\]|--)>\s*$/g;t.extend({htmlPrefilter:function(c){return c.replace(Gb,"\x3c$1\x3e\x3c/$2\x3e")},clone:function(c,a,b){var d,g=c.cloneNode(!0),p=t.contains(c.ownerDocument,c);if(!(P.noCloneChecked||1!==c.nodeType&&11!==c.nodeType||t.isXMLDoc(c))){var h=m(g);var e=m(c);var l=0;for(d=e.length;l<d;l++){var f=e[l],v=h[l],k=v.nodeName.toLowerCase();if("input"===k&&db.test(f.type))v.checked=
f.checked;else if("input"===k||"textarea"===k)v.defaultValue=f.defaultValue}}if(a)if(b)for(e=e||m(c),h=h||m(g),l=0,d=e.length;l<d;l++)B(e[l],h[l]);else B(c,g);h=m(g,"script");0<h.length&&x(h,!p&&m(c,"script"));return g},cleanData:function(c){for(var a,b,d,g=t.event.special,p=0;(b=c[p])!==n;p++)if(ya(b)){if(a=b[L.expando]){if(a.events)for(d in a.events)g[d]?t.event.remove(b,d):t.removeEvent(b,d,a.handle);b[L.expando]=n}b[W.expando]&&(b[W.expando]=n)}}});t.fn.extend({domManip:q,detach:function(c){return E(this,
c,!0)},remove:function(c){return E(this,c)},text:function(c){return fa(this,function(c){return c===n?t.text(this):this.empty().each(function(){if(1===this.nodeType||11===this.nodeType||9===this.nodeType)this.textContent=c})},null,c,arguments.length)},append:function(){return q(this,arguments,function(c){1!==this.nodeType&&11!==this.nodeType&&9!==this.nodeType||p(this,c).appendChild(c)})},prepend:function(){return q(this,arguments,function(c){if(1===this.nodeType||11===this.nodeType||9===this.nodeType){var a=
p(this,c);a.insertBefore(c,a.firstChild)}})},before:function(){return q(this,arguments,function(c){this.parentNode&&this.parentNode.insertBefore(c,this)})},after:function(){return q(this,arguments,function(c){this.parentNode&&this.parentNode.insertBefore(c,this.nextSibling)})},empty:function(){for(var c,a=0;null!=(c=this[a]);a++)1===c.nodeType&&(t.cleanData(m(c,!1)),c.textContent="");return this},clone:function(c,a){c=null==c?!1:c;a=null==a?c:a;return this.map(function(){return t.clone(this,c,a)})},
html:function(c){return fa(this,function(c){var a=this[0]||{},b=0,d=this.length;if(c===n&&1===a.nodeType)return a.innerHTML;if("string"===typeof c&&!Hb.test(c)&&!ba[(Ua.exec(c)||["",""])[1].toLowerCase()]){c=t.htmlPrefilter(c);try{for(;b<d;b++)a=this[b]||{},1===a.nodeType&&(t.cleanData(m(a,!1)),a.innerHTML=c);a=0}catch(cc){}}a&&this.empty().append(c)},null,c,arguments.length)},replaceWith:function(){var c=[];return q(this,arguments,function(a){var b=this.parentNode;0>t.inArray(this,c)&&(t.cleanData(m(this)),
b&&b.replaceChild(a,this))},c)}});t.each({appendTo:"append",prependTo:"prepend",insertBefore:"before",insertAfter:"after",replaceAll:"replaceWith"},function(c,a){t.fn[c]=function(c){for(var b=[],d=t(c),g=d.length-1,p=0;p<=g;p++)c=p===g?this:this.clone(!0),t(d[p])[a](c),xa.apply(b,c.get());return this.pushStack(b)}});var Ea,Wa={HTML:"block",BODY:"block"},Xa=/^margin/,Ja=new RegExp("^("+cb+")(?!px)[a-z%]+$","i"),Fa=function(c){var a=c.ownerDocument.defaultView;a&&a.opener||(a=f);return a.getComputedStyle(c)},
Na=function(c,a,b,d){var g,p={};for(g in a)p[g]=c.style[g],c.style[g]=a[g];b=b.apply(c,d||[]);for(g in a)c.style[g]=p[g];return b},za=I.documentElement;(function(){function c(){h.style.cssText="-webkit-box-sizing:border-box;-moz-box-sizing:border-box;box-sizing:border-box;position:relative;display:block;margin:auto;border:1px;padding:1px;top:1%;width:50%";h.innerHTML="";za.appendChild(p);var c=f.getComputedStyle(h);a="1%"!==c.top;g="2px"===c.marginLeft;b="4px"===c.width;h.style.marginRight="50%";
d="4px"===c.marginRight;za.removeChild(p)}var a,b,d,g,p=I.createElement("div"),h=I.createElement("div");h.style&&(h.style.backgroundClip="content-box",h.cloneNode(!0).style.backgroundClip="",P.clearCloneStyle="content-box"===h.style.backgroundClip,p.style.cssText="border:0;width:8px;height:0;top:0;left:-9999px;padding:0;margin-top:1px;position:absolute",p.appendChild(h),t.extend(P,{pixelPosition:function(){c();return a},boxSizingReliable:function(){null==b&&c();return b},pixelMarginRight:function(){null==
b&&c();return d},reliableMarginLeft:function(){null==b&&c();return g},reliableMarginRight:function(){var c=h.appendChild(I.createElement("div"));c.style.cssText=h.style.cssText="-webkit-box-sizing:content-box;box-sizing:content-box;display:block;margin:0;border:0;padding:0";c.style.marginRight=c.style.width="0";h.style.width="1px";za.appendChild(p);var a=!parseFloat(f.getComputedStyle(c).marginRight);za.removeChild(p);h.removeChild(c);return a}}))})();var Ib=/^(none|table(?!-c[ea]).+)/,Jb={position:"absolute",
visibility:"hidden",display:"block"},fb={letterSpacing:"0",fontWeight:"400"},Za=["Webkit","O","Moz","ms"],Ya=I.createElement("div").style;t.extend({cssHooks:{opacity:{get:function(c,a){if(a)return c=J(c,"opacity"),""===c?"1":c}}},cssNumber:{animationIterationCount:!0,columnCount:!0,fillOpacity:!0,flexGrow:!0,flexShrink:!0,fontWeight:!0,lineHeight:!0,opacity:!0,order:!0,orphans:!0,widows:!0,zIndex:!0,zoom:!0},cssProps:{"float":"cssFloat"},style:function(c,a,b,d){if(c&&3!==c.nodeType&&8!==c.nodeType&&
c.style){var g,p=t.camelCase(a),h=c.style;a=t.cssProps[p]||(t.cssProps[p]=X(p)||p);var e=t.cssHooks[a]||t.cssHooks[p];if(b!==n){var m=typeof b;"string"===m&&(g=va.exec(b))&&g[1]&&(b=v(c,a,g),m="number");null!=b&&b===b&&("number"===m&&(b+=g&&g[3]||(t.cssNumber[p]?"":"px")),P.clearCloneStyle||""!==b||0!==a.indexOf("background")||(h[a]="inherit"),e&&"set"in e&&(b=e.set(c,b,d))===n||(h[a]=b))}else return e&&"get"in e&&(g=e.get(c,!1,d))!==n?g:h[a]}},css:function(c,a,b,d){var g;var p=t.camelCase(a);a=t.cssProps[p]||
(t.cssProps[p]=X(p)||p);(p=t.cssHooks[a]||t.cssHooks[p])&&"get"in p&&(g=p.get(c,!0,b));g===n&&(g=J(c,a,d));"normal"===g&&a in fb&&(g=fb[a]);return""===b||b?(c=parseFloat(g),!0===b||isFinite(c)?c||0:g):g}});t.each(["height","width"],function(c,a){t.cssHooks[a]={get:function(c,b,d){if(b)return Ib.test(t.css(c,"display"))&&0===c.offsetWidth?Na(c,Jb,function(){return ca(c,a,d)}):ca(c,a,d)},set:function(c,b,d){var g,p=d&&Fa(c);(d=d&&Q(c,a,d,"border-box"===t.css(c,"boxSizing",!1,p),p))&&(g=va.exec(b))&&
"px"!==(g[3]||"px")&&(c.style[a]=b,b=t.css(c,a));return na(c,b,d)}}});t.cssHooks.marginLeft=H(P.reliableMarginLeft,function(c,a){if(a)return(parseFloat(J(c,"marginLeft"))||c.getBoundingClientRect().left-Na(c,{marginLeft:0},function(){return c.getBoundingClientRect().left}))+"px"});t.cssHooks.marginRight=H(P.reliableMarginRight,function(c,a){if(a)return Na(c,{display:"inline-block"},J,[c,"marginRight"])});t.each({margin:"",padding:"",border:"Width"},function(c,a){t.cssHooks[c+a]={expand:function(b){var d=
0,g={};for(b="string"===typeof b?b.split(" "):[b];4>d;d++)g[c+ka[d]+a]=b[d]||b[d-2]||b[0];return g}};Xa.test(c)||(t.cssHooks[c+a].set=na)});t.fn.extend({css:function(c,a){return fa(this,function(c,a,b){var d,g={},p=0;if(t.isArray(a)){b=Fa(c);for(d=a.length;p<d;p++)g[a[p]]=t.css(c,a[p],!1,b);return g}return b!==n?t.style(c,a,b):t.css(c,a)},c,a,1<arguments.length)},show:function(){return da(this,!0)},hide:function(){return da(this)},toggle:function(c){return"boolean"===typeof c?c?this.show():this.hide():
this.each(function(){wa(this)?t(this).show():t(this).hide()})}});t.Tween=M;M.prototype={constructor:M,init:function(c,a,b,d,g,p){this.elem=c;this.prop=b;this.easing=g||t.easing._default;this.options=a;this.start=this.now=this.cur();this.end=d;this.unit=p||(t.cssNumber[b]?"":"px")},cur:function(){var c=M.propHooks[this.prop];return c&&c.get?c.get(this):M.propHooks._default.get(this)},run:function(c){var a,b=M.propHooks[this.prop];this.pos=this.options.duration?a=t.easing[this.easing](c,this.options.duration*
c,0,1,this.options.duration):a=c;this.now=(this.end-this.start)*a+this.start;this.options.step&&this.options.step.call(this.elem,this.now,this);b&&b.set?b.set(this):M.propHooks._default.set(this);return this}};M.prototype.init.prototype=M.prototype;M.propHooks={_default:{get:function(c){return 1!==c.elem.nodeType||null!=c.elem[c.prop]&&null==c.elem.style[c.prop]?c.elem[c.prop]:(c=t.css(c.elem,c.prop,""))&&"auto"!==c?c:0},set:function(c){if(t.fx.step[c.prop])t.fx.step[c.prop](c);else 1!==c.elem.nodeType||
null==c.elem.style[t.cssProps[c.prop]]&&!t.cssHooks[c.prop]?c.elem[c.prop]=c.now:t.style(c.elem,c.prop,c.now+c.unit)}}};M.propHooks.scrollTop=M.propHooks.scrollLeft={set:function(c){c.elem.nodeType&&c.elem.parentNode&&(c.elem[c.prop]=c.now)}};t.easing={linear:function(c){return c},swing:function(c){return.5-Math.cos(c*Math.PI)/2},_default:"swing"};t.fx=M.prototype.init;t.fx.step={};var pa,Ha,Kb=/^(?:toggle|show|hide)$/,Lb=/queueHooks$/;t.Animation=t.extend(V,{tweeners:{"*":[function(c,a){var b=this.createTween(c,
a);v(b.elem,c,va.exec(a),b);return b}]},tweener:function(c,a){t.isFunction(c)?(a=c,c=["*"]):c=c.match(ia);for(var b,d=0,g=c.length;d<g;d++)b=c[d],V.tweeners[b]=V.tweeners[b]||[],V.tweeners[b].unshift(a)},prefilters:[function(c,a,b){var d,g=this,p={},h=c.style,e=c.nodeType&&wa(c),m=L.get(c,"fxshow");if(!b.queue){var l=t._queueHooks(c,"fx");if(null==l.unqueued){l.unqueued=0;var f=l.empty.fire;l.empty.fire=function(){l.unqueued||f()}}l.unqueued++;g.always(function(){g.always(function(){l.unqueued--;
t.queue(c,"fx").length||l.empty.fire()})})}if(1===c.nodeType&&("height"in a||"width"in a)){b.overflow=[h.overflow,h.overflowX,h.overflowY];var v=t.css(c,"display");var k="none"===v?L.get(c,"olddisplay")||G(c.nodeName):v;"inline"===k&&"none"===t.css(c,"float")&&(h.display="inline-block")}b.overflow&&(h.overflow="hidden",g.always(function(){h.overflow=b.overflow[0];h.overflowX=b.overflow[1];h.overflowY=b.overflow[2]}));for(d in a)if(k=a[d],Kb.exec(k)){delete a[d];var A=A||"toggle"===k;if(k===(e?"hide":
"show"))if("show"===k&&m&&m[d]!==n)e=!0;else continue;p[d]=m&&m[d]||t.style(c,d)}else v=n;if(t.isEmptyObject(p))"inline"===("none"===v?G(c.nodeName):v)&&(h.display=v);else for(d in m?"hidden"in m&&(e=m.hidden):m=L.access(c,"fxshow",{}),A&&(m.hidden=!e),e?t(c).show():g.done(function(){t(c).hide()}),g.done(function(){var a;L.remove(c,"fxshow");for(a in p)t.style(c,a,p[a])}),p)a=ra(e?m[d]:0,d,g),d in m||(m[d]=a.start,e&&(a.end=a.start,a.start="width"===d||"height"===d?1:0))}],prefilter:function(c,a){a?
V.prefilters.unshift(c):V.prefilters.push(c)}});t.speed=function(c,a,b){var d=c&&"object"===typeof c?t.extend({},c):{complete:b||!b&&a||t.isFunction(c)&&c,duration:c,easing:b&&a||a&&!t.isFunction(a)&&a};d.duration=t.fx.off?0:"number"===typeof d.duration?d.duration:d.duration in t.fx.speeds?t.fx.speeds[d.duration]:t.fx.speeds._default;if(null==d.queue||!0===d.queue)d.queue="fx";d.old=d.complete;d.complete=function(){t.isFunction(d.old)&&d.old.call(this);d.queue&&t.dequeue(this,d.queue)};return d};
t.fn.extend({fadeTo:function(c,a,b,d){return this.filter(wa).css("opacity",0).show().end().animate({opacity:a},c,b,d)},animate:function(c,a,b,d){var g=t.isEmptyObject(c),p=t.speed(a,b,d);a=function(){var a=V(this,t.extend({},c),p);(g||L.get(this,"finish"))&&a.stop(!0)};a.finish=a;return g||!1===p.queue?this.each(a):this.queue(p.queue,a)},stop:function(c,a,b){var d=function(c){var a=c.stop;delete c.stop;a(b)};"string"!==typeof c&&(b=a,a=c,c=n);a&&!1!==c&&this.queue(c||"fx",[]);return this.each(function(){var a=
!0,g=null!=c&&c+"queueHooks",p=t.timers,h=L.get(this);if(g)h[g]&&h[g].stop&&d(h[g]);else for(g in h)h[g]&&h[g].stop&&Lb.test(g)&&d(h[g]);for(g=p.length;g--;)p[g].elem!==this||null!=c&&p[g].queue!==c||(p[g].anim.stop(b),a=!1,p.splice(g,1));!a&&b||t.dequeue(this,c)})},finish:function(c){!1!==c&&(c=c||"fx");return this.each(function(){var a=L.get(this),b=a[c+"queue"];var d=a[c+"queueHooks"];var g=t.timers,p=b?b.length:0;a.finish=!0;t.queue(this,c,[]);d&&d.stop&&d.stop.call(this,!0);for(d=g.length;d--;)g[d].elem===
this&&g[d].queue===c&&(g[d].anim.stop(!0),g.splice(d,1));for(d=0;d<p;d++)b[d]&&b[d].finish&&b[d].finish.call(this);delete a.finish})}});t.each(["toggle","show","hide"],function(c,a){var b=t.fn[a];t.fn[a]=function(c,d,g){return null==c||"boolean"===typeof c?b.apply(this,arguments):this.animate(qa(a,!0),c,d,g)}});t.each({slideDown:qa("show"),slideUp:qa("hide"),slideToggle:qa("toggle"),fadeIn:{opacity:"show"},fadeOut:{opacity:"hide"},fadeToggle:{opacity:"toggle"}},function(c,a){t.fn[c]=function(c,b,
d){return this.animate(a,c,b,d)}});t.timers=[];t.fx.tick=function(){var c=0,a=t.timers;for(pa=t.now();c<a.length;c++){var b=a[c];b()||a[c]!==b||a.splice(c--,1)}a.length||t.fx.stop();pa=n};t.fx.timer=function(c){t.timers.push(c);c()?t.fx.start():t.timers.pop()};t.fx.interval=13;t.fx.start=function(){Ha||(Ha=f.setInterval(t.fx.tick,t.fx.interval))};t.fx.stop=function(){f.clearInterval(Ha);Ha=null};t.fx.speeds={slow:600,fast:200,_default:400};t.fn.delay=function(c,a){c=t.fx?t.fx.speeds[c]||c:c;return this.queue(a||
"fx",function(a,b){var d=f.setTimeout(a,c);b.stop=function(){f.clearTimeout(d)}})};(function(){var c=I.createElement("input"),a=I.createElement("select"),b=a.appendChild(I.createElement("option"));c.type="checkbox";P.checkOn=""!==c.value;P.optSelected=b.selected;a.disabled=!0;P.optDisabled=!b.disabled;c=I.createElement("input");c.value="t";c.type="radio";P.radioValue="t"===c.value})();var Aa=t.expr.attrHandle;t.fn.extend({attr:function(c,a){return fa(this,t.attr,c,a,1<arguments.length)},removeAttr:function(c){return this.each(function(){t.removeAttr(this,
c)})}});t.extend({attr:function(c,a,b){var d,g=c.nodeType;if(3!==g&&8!==g&&2!==g){if("undefined"===typeof c.getAttribute)return t.prop(c,a,b);if(1!==g||!t.isXMLDoc(c)){a=a.toLowerCase();var p=t.attrHooks[a]||(t.expr.match.bool.test(a)?Mb:n)}if(b!==n){if(null===b){t.removeAttr(c,a);return}if(p&&"set"in p&&(d=p.set(c,b,a))!==n)return d;c.setAttribute(a,b+"");return b}if(p&&"get"in p&&null!==(d=p.get(c,a)))return d;d=t.find.attr(c,a);return null==d?n:d}},attrHooks:{type:{set:function(c,a){if(!P.radioValue&&
"radio"===a&&t.nodeName(c,"input")){var b=c.value;c.setAttribute("type",a);b&&(c.value=b);return a}}}},removeAttr:function(c,a){var b=0,d=a&&a.match(ia);if(d&&1===c.nodeType)for(;a=d[b++];){var g=t.propFix[a]||a;t.expr.match.bool.test(a)&&(c[g]=!1);c.removeAttribute(a)}}});var Mb={set:function(c,a,b){!1===a?t.removeAttr(c,b):c.setAttribute(b,b);return b}};t.each(t.expr.match.bool.source.match(/\w+/g),function(c,a){var b=Aa[a]||t.find.attr;Aa[a]=function(c,a,d){if(!d){var g=Aa[a];Aa[a]=p;var p=null!=
b(c,a,d)?a.toLowerCase():null;Aa[a]=g}return p}});var Nb=/^(?:input|select|textarea|button)$/i,Ob=/^(?:a|area)$/i;t.fn.extend({prop:function(c,a){return fa(this,t.prop,c,a,1<arguments.length)},removeProp:function(c){return this.each(function(){delete this[t.propFix[c]||c]})}});t.extend({prop:function(c,a,b){var d,g=c.nodeType;if(3!==g&&8!==g&&2!==g){if(1!==g||!t.isXMLDoc(c)){a=t.propFix[a]||a;var p=t.propHooks[a]}return b!==n?p&&"set"in p&&(d=p.set(c,b,a))!==n?d:c[a]=b:p&&"get"in p&&null!==(d=p.get(c,
a))?d:c[a]}},propHooks:{tabIndex:{get:function(c){var a=t.find.attr(c,"tabindex");return a?parseInt(a,10):Nb.test(c.nodeName)||Ob.test(c.nodeName)&&c.href?0:-1}}},propFix:{"for":"htmlFor","class":"className"}});P.optSelected||(t.propHooks.selected={get:function(c){(c=c.parentNode)&&c.parentNode&&c.parentNode.selectedIndex;return null},set:function(c){if(c=c.parentNode)c.selectedIndex,c.parentNode&&c.parentNode.selectedIndex}});t.each("tabIndex readOnly maxLength cellSpacing cellPadding rowSpan colSpan useMap frameBorder contentEditable".split(" "),
function(){t.propFix[this.toLowerCase()]=this});var Oa=/[\t\r\n\f]/g;t.fn.extend({addClass:function(c){var a,b,d,g,p,h=0;if(t.isFunction(c))return this.each(function(a){t(this).addClass(c.call(this,a,Y(this)))});if("string"===typeof c&&c)for(a=c.match(ia)||[];b=this[h++];){var e=Y(b);if(d=1===b.nodeType&&(" "+e+" ").replace(Oa," ")){for(p=0;g=a[p++];)0>d.indexOf(" "+g+" ")&&(d+=g+" ");d=t.trim(d);e!==d&&b.setAttribute("class",d)}}return this},removeClass:function(c){var a,b,d,g,p,h=0;if(t.isFunction(c))return this.each(function(a){t(this).removeClass(c.call(this,
a,Y(this)))});if(!arguments.length)return this.attr("class","");if("string"===typeof c&&c)for(a=c.match(ia)||[];b=this[h++];){var e=Y(b);if(d=1===b.nodeType&&(" "+e+" ").replace(Oa," ")){for(p=0;g=a[p++];)for(;-1<d.indexOf(" "+g+" ");)d=d.replace(" "+g+" "," ");d=t.trim(d);e!==d&&b.setAttribute("class",d)}}return this},toggleClass:function(c,a){var b=typeof c;return"boolean"===typeof a&&"string"===b?a?this.addClass(c):this.removeClass(c):t.isFunction(c)?this.each(function(b){t(this).toggleClass(c.call(this,
b,Y(this),a),a)}):this.each(function(){var a,d;if("string"===b){var g=0;var p=t(this);for(d=c.match(ia)||[];a=d[g++];)p.hasClass(a)?p.removeClass(a):p.addClass(a)}else if(c===n||"boolean"===b)(a=Y(this))&&L.set(this,"__className__",a),this.setAttribute&&this.setAttribute("class",a||!1===c?"":L.get(this,"__className__")||"")})},hasClass:function(c){var a,b=0;for(c=" "+c+" ";a=this[b++];)if(1===a.nodeType&&-1<(" "+Y(a)+" ").replace(Oa," ").indexOf(c))return!0;return!1}});var Pb=/\r/g,Qb=/[\x20\t\r\n\f]+/g;
t.fn.extend({val:function(c){var a,b,d=this[0];if(arguments.length){var g=t.isFunction(c);return this.each(function(b){1===this.nodeType&&(b=g?c.call(this,b,t(this).val()):c,null==b?b="":"number"===typeof b?b+="":t.isArray(b)&&(b=t.map(b,function(c){return null==c?"":c+""})),a=t.valHooks[this.type]||t.valHooks[this.nodeName.toLowerCase()],a&&"set"in a&&a.set(this,b,"value")!==n||(this.value=b))})}if(d){if((a=t.valHooks[d.type]||t.valHooks[d.nodeName.toLowerCase()])&&"get"in a&&(b=a.get(d,"value"))!==
n)return b;b=d.value;return"string"===typeof b?b.replace(Pb,""):null==b?"":b}}});t.extend({valHooks:{option:{get:function(c){var a=t.find.attr(c,"value");return null!=a?a:t.trim(t.text(c)).replace(Qb," ")}},select:{get:function(c){for(var a,b=c.options,d=c.selectedIndex,g=(c="select-one"===c.type||0>d)?null:[],p=c?d+1:b.length,h=0>d?p:c?d:0;h<p;h++)if(a=b[h],!(!a.selected&&h!==d||(P.optDisabled?a.disabled:null!==a.getAttribute("disabled"))||a.parentNode.disabled&&t.nodeName(a.parentNode,"optgroup"))){a=
t(a).val();if(c)return a;g.push(a)}return g},set:function(c,a){for(var b,d=c.options,g=t.makeArray(a),p=d.length;p--;)if(a=d[p],a.selected=-1<t.inArray(t.valHooks.option.get(a),g))b=!0;b||(c.selectedIndex=-1);return g}}}});t.each(["radio","checkbox"],function(){t.valHooks[this]={set:function(c,a){if(t.isArray(a))return c.checked=-1<t.inArray(t(c).val(),a)}};P.checkOn||(t.valHooks[this].get=function(c){return null===c.getAttribute("value")?"on":c.value})});var gb=/^(?:focusinfocus|focusoutblur)$/;
t.extend(t.event,{trigger:function(c,a,b,d){var g,p,h=[b||I],e=ma.call(c,"type")?c.type:c;var m=ma.call(c,"namespace")?c.namespace.split("."):[];var l=g=b=b||I;if(3!==b.nodeType&&8!==b.nodeType&&!gb.test(e+t.event.triggered)){-1<e.indexOf(".")&&(m=e.split("."),e=m.shift(),m.sort());var v=0>e.indexOf(":")&&"on"+e;c=c[t.expando]?c:new t.Event(e,"object"===typeof c&&c);c.isTrigger=d?2:3;c.namespace=m.join(".");c.rnamespace=c.namespace?new RegExp("(^|\\.)"+m.join("\\.(?:.*\\.|)")+"(\\.|$)"):null;c.result=
n;c.target||(c.target=b);a=null==a?[c]:t.makeArray(a,[c]);m=t.event.special[e]||{};if(d||!m.trigger||!1!==m.trigger.apply(b,a)){if(!d&&!m.noBubble&&!t.isWindow(b)){var k=m.delegateType||e;gb.test(k+e)||(l=l.parentNode);for(;l;l=l.parentNode)h.push(l),g=l;g===(b.ownerDocument||I)&&h.push(g.defaultView||g.parentWindow||f)}for(g=0;(l=h[g++])&&!c.isPropagationStopped();)c.type=1<g?k:m.bindType||e,(p=(L.get(l,"events")||{})[c.type]&&L.get(l,"handle"))&&p.apply(l,a),(p=v&&l[v])&&p.apply&&ya(l)&&(c.result=
p.apply(l,a),!1===c.result&&c.preventDefault());c.type=e;d||c.isDefaultPrevented()||m._default&&!1!==m._default.apply(h.pop(),a)||!ya(b)||!v||!t.isFunction(b[e])||t.isWindow(b)||((g=b[v])&&(b[v]=null),t.event.triggered=e,b[e](),t.event.triggered=n,g&&(b[v]=g));return c.result}}},simulate:function(c,a,b){c=t.extend(new t.Event,b,{type:c,isSimulated:!0});t.event.trigger(c,null,a)}});t.fn.extend({trigger:function(c,a){return this.each(function(){t.event.trigger(c,a,this)})},triggerHandler:function(c,
a){var b=this[0];if(b)return t.event.trigger(c,a,b,!0)}});t.each("blur focus focusin focusout load resize scroll unload click dblclick mousedown mouseup mousemove mouseover mouseout mouseenter mouseleave change select submit keydown keypress keyup error contextmenu".split(" "),function(c,a){t.fn[a]=function(c,b){return 0<arguments.length?this.on(a,null,c,b):this.trigger(a)}});t.fn.extend({hover:function(c,a){return this.mouseenter(c).mouseleave(a||c)}});P.focusin="onfocusin"in f;P.focusin||t.each({focus:"focusin",
blur:"focusout"},function(c,a){var b=function(c){t.event.simulate(a,c.target,t.event.fix(c))};t.event.special[a]={setup:function(){var d=this.ownerDocument||this,g=L.access(d,a);g||d.addEventListener(c,b,!0);L.access(d,a,(g||0)+1)},teardown:function(){var d=this.ownerDocument||this,g=L.access(d,a)-1;g?L.access(d,a,g):(d.removeEventListener(c,b,!0),L.remove(d,a))}}});var Ba=f.location,Pa=t.now(),Qa=/\?/;t.parseJSON=function(c){return JSON.parse(c+"")};t.parseXML=function(c){if(!c||"string"!==typeof c)return null;
try{var a=(new f.DOMParser).parseFromString(c,"text/xml")}catch(ac){a=n}a&&!a.getElementsByTagName("parsererror").length||t.error("Invalid XML: "+c);return a};var Rb=/#.*$/,hb=/([?&])_=[^&]*/,Sb=/^(.*?):[ \t]*([^\r\n]*)$/mg,Tb=/^(?:GET|HEAD)$/,Ub=/^\/\//,ib={},Ka={},jb="*/".concat("*"),Ra=I.createElement("a");Ra.href=Ba.href;t.extend({active:0,lastModified:{},etag:{},ajaxSettings:{url:Ba.href,type:"GET",isLocal:/^(?:about|app|app-storage|.+-extension|file|res|widget):$/.test(Ba.protocol),global:!0,
processData:!0,async:!0,contentType:"application/x-www-form-urlencoded; charset\x3dUTF-8",accepts:{"*":jb,text:"text/plain",html:"text/html",xml:"application/xml, text/xml",json:"application/json, text/javascript"},contents:{xml:/\bxml\b/,html:/\bhtml/,json:/\bjson\b/},responseFields:{xml:"responseXML",text:"responseText",json:"responseJSON"},converters:{"* text":String,"text html":!0,"text json":t.parseJSON,"text xml":t.parseXML},flatOptions:{url:!0,context:!0}},ajaxSetup:function(c,a){return a?
N(N(c,t.ajaxSettings),a):N(t.ajaxSettings,c)},ajaxPrefilter:T(ib),ajaxTransport:T(Ka),ajax:function(c,a){function b(c,a,b,p){var m=a;if(2!==z){z=2;h&&f.clearTimeout(h);d=n;g=p||"";C.readyState=0<c?4:0;p=200<=c&&300>c||304===c;if(b){var w=l;for(var r=C,B,q,D,E,G=w.contents,K=w.dataTypes;"*"===K[0];)K.shift(),B===n&&(B=w.mimeType||r.getResponseHeader("Content-Type"));if(B)for(q in G)if(G[q]&&G[q].test(B)){K.unshift(q);break}if(K[0]in b)D=K[0];else{for(q in b){if(!K[0]||w.converters[q+" "+K[0]]){D=q;
break}E||(E=q)}D=D||E}D?(D!==K[0]&&K.unshift(D),w=b[D]):w=void 0}a:{b=l;B=w;q=C;D=p;var F;r={};G=b.dataTypes.slice();if(G[1])for(H in b.converters)r[H.toLowerCase()]=b.converters[H];for(E=G.shift();E;){b.responseFields[E]&&(q[b.responseFields[E]]=B);!J&&D&&b.dataFilter&&(B=b.dataFilter(B,b.dataType));var J=E;if(E=G.shift())if("*"===E)E=J;else if("*"!==J&&J!==E){var H=r[J+" "+E]||r["* "+E];if(!H)for(F in r)if(w=F.split(" "),w[1]===E&&(H=r[J+" "+w[0]]||r["* "+w[0]])){!0===H?H=r[F]:!0!==r[F]&&(E=w[0],
G.unshift(w[1]));break}if(!0!==H)if(H&&b.throws)B=H(B);else try{B=H(B)}catch(zb){w={state:"parsererror",error:H?zb:"No conversion from "+J+" to "+E};break a}}}w={state:"success",data:B}}if(p)if(l.ifModified&&((m=C.getResponseHeader("Last-Modified"))&&(t.lastModified[y]=m),(m=C.getResponseHeader("etag"))&&(t.etag[y]=m)),204===c||"HEAD"===l.type)m="nocontent";else if(304===c)m="notmodified";else{m=w.state;var X=w.data;var Q=w.error;p=!Q}else if(Q=m,c||!m)m="error",0>c&&(c=0);C.status=c;C.statusText=
(a||m)+"";p?A.resolveWith(v,[X,m,C]):A.rejectWith(v,[C,m,Q]);C.statusCode(u);u=n;e&&k.trigger(p?"ajaxSuccess":"ajaxError",[C,l,p?X:Q]);x.fireWith(v,[C,m]);e&&(k.trigger("ajaxComplete",[C,l]),--t.active||t.event.trigger("ajaxStop"))}}"object"===typeof c&&(a=c,c=n);a=a||{};var d,g,p,h,e,m,l=t.ajaxSetup({},a),v=l.context||l,k=l.context&&(v.nodeType||v.jquery)?t(v):t.event,A=t.Deferred(),x=t.Callbacks("once memory"),u=l.statusCode||{},w={},r={},z=0,B="canceled",C={readyState:0,getResponseHeader:function(c){var a;
if(2===z){if(!p)for(p={};a=Sb.exec(g);)p[a[1].toLowerCase()]=a[2];a=p[c.toLowerCase()]}return null==a?null:a},getAllResponseHeaders:function(){return 2===z?g:null},setRequestHeader:function(c,a){var b=c.toLowerCase();z||(c=r[b]=r[b]||c,w[c]=a);return this},overrideMimeType:function(c){z||(l.mimeType=c);return this},statusCode:function(c){var a;if(c)if(2>z)for(a in c)u[a]=[u[a],c[a]];else C.always(c[C.status]);return this},abort:function(c){c=c||B;d&&d.abort(c);b(0,c);return this}};A.promise(C).complete=
x.add;C.success=C.done;C.error=C.fail;l.url=((c||l.url||Ba.href)+"").replace(Rb,"").replace(Ub,Ba.protocol+"//");l.type=a.method||a.type||l.method||l.type;l.dataTypes=t.trim(l.dataType||"*").toLowerCase().match(ia)||[""];if(null==l.crossDomain){c=I.createElement("a");try{c.href=l.url,c.href=c.href,l.crossDomain=Ra.protocol+"//"+Ra.host!==c.protocol+"//"+c.host}catch(Ma){l.crossDomain=!0}}l.data&&l.processData&&"string"!==typeof l.data&&(l.data=t.param(l.data,l.traditional));R(ib,l,a,C);if(2===z)return C;
(e=t.event&&l.global)&&0===t.active++&&t.event.trigger("ajaxStart");l.type=l.type.toUpperCase();l.hasContent=!Tb.test(l.type);var y=l.url;l.hasContent||(l.data&&(y=l.url+=(Qa.test(y)?"\x26":"?")+l.data,delete l.data),!1===l.cache&&(l.url=hb.test(y)?y.replace(hb,"$1_\x3d"+Pa++):y+(Qa.test(y)?"\x26":"?")+"_\x3d"+Pa++));l.ifModified&&(t.lastModified[y]&&C.setRequestHeader("If-Modified-Since",t.lastModified[y]),t.etag[y]&&C.setRequestHeader("If-None-Match",t.etag[y]));(l.data&&l.hasContent&&!1!==l.contentType||
a.contentType)&&C.setRequestHeader("Content-Type",l.contentType);C.setRequestHeader("Accept",l.dataTypes[0]&&l.accepts[l.dataTypes[0]]?l.accepts[l.dataTypes[0]]+("*"!==l.dataTypes[0]?", "+jb+"; q\x3d0.01":""):l.accepts["*"]);for(m in l.headers)C.setRequestHeader(m,l.headers[m]);if(l.beforeSend&&(!1===l.beforeSend.call(v,C,l)||2===z))return C.abort();B="abort";for(m in{success:1,error:1,complete:1})C[m](l[m]);if(d=R(Ka,l,a,C)){C.readyState=1;e&&k.trigger("ajaxSend",[C,l]);if(2===z)return C;l.async&&
0<l.timeout&&(h=f.setTimeout(function(){C.abort("timeout")},l.timeout));try{z=1,d.send(w,b)}catch(Ma){if(2>z)b(-1,Ma);else throw Ma;}}else b(-1,"No Transport");return C},getJSON:function(c,a,b){return t.get(c,a,b,"json")},getScript:function(c,a){return t.get(c,n,a,"script")}});t.each(["get","post"],function(c,a){t[a]=function(c,b,d,g){t.isFunction(b)&&(g=g||d,d=b,b=n);return t.ajax(t.extend({url:c,type:a,dataType:g,data:b,success:d},t.isPlainObject(c)&&c))}});t._evalUrl=function(c){return t.ajax({url:c,
type:"GET",dataType:"script",async:!1,global:!1,"throws":!0})};t.fn.extend({wrapAll:function(c){if(t.isFunction(c))return this.each(function(a){t(this).wrapAll(c.call(this,a))});if(this[0]){var a=t(c,this[0].ownerDocument).eq(0).clone(!0);this[0].parentNode&&a.insertBefore(this[0]);a.map(function(){for(var c=this;c.firstElementChild;)c=c.firstElementChild;return c}).append(this)}return this},wrapInner:function(c){return t.isFunction(c)?this.each(function(a){t(this).wrapInner(c.call(this,a))}):this.each(function(){var a=
t(this),b=a.contents();b.length?b.wrapAll(c):a.append(c)})},wrap:function(c){var a=t.isFunction(c);return this.each(function(b){t(this).wrapAll(a?c.call(this,b):c)})},unwrap:function(){return this.parent().each(function(){t.nodeName(this,"body")||t(this).replaceWith(this.childNodes)}).end()}});t.expr.filters.hidden=function(c){return!t.expr.filters.visible(c)};t.expr.filters.visible=function(c){return 0<c.offsetWidth||0<c.offsetHeight||0<c.getClientRects().length};var Vb=/%20/g,vb=/\[\]$/,kb=/\r?\n/g,
Wb=/^(?:submit|button|image|reset|file)$/i,Xb=/^(?:input|select|textarea|keygen)/i;t.param=function(c,a){var b,d=[],g=function(c,a){a=t.isFunction(a)?a():null==a?"":a;d[d.length]=encodeURIComponent(c)+"\x3d"+encodeURIComponent(a)};a===n&&(a=t.ajaxSettings&&t.ajaxSettings.traditional);if(t.isArray(c)||c.jquery&&!t.isPlainObject(c))t.each(c,function(){g(this.name,this.value)});else for(b in c)S(b,c[b],a,g);return d.join("\x26").replace(Vb,"+")};t.fn.extend({serialize:function(){return t.param(this.serializeArray())},
serializeArray:function(){return this.map(function(){var c=t.prop(this,"elements");return c?t.makeArray(c):this}).filter(function(){var c=this.type;return this.name&&!t(this).is(":disabled")&&Xb.test(this.nodeName)&&!Wb.test(c)&&(this.checked||!db.test(c))}).map(function(c,a){c=t(this).val();return null==c?null:t.isArray(c)?t.map(c,function(c){return{name:a.name,value:c.replace(kb,"\r\n")}}):{name:a.name,value:c.replace(kb,"\r\n")}}).get()}});t.ajaxSettings.xhr=function(){try{return new f.XMLHttpRequest}catch(F){}};
var Yb={0:200,1223:204},Ca=t.ajaxSettings.xhr();P.cors=!!Ca&&"withCredentials"in Ca;P.ajax=Ca=!!Ca;t.ajaxTransport(function(c){var a,b;if(P.cors||Ca&&!c.crossDomain)return{send:function(d,g){var p,h=c.xhr();h.open(c.type,c.url,c.async,c.username,c.password);if(c.xhrFields)for(p in c.xhrFields)h[p]=c.xhrFields[p];c.mimeType&&h.overrideMimeType&&h.overrideMimeType(c.mimeType);c.crossDomain||d["X-Requested-With"]||(d["X-Requested-With"]="XMLHttpRequest");for(p in d)h.setRequestHeader(p,d[p]);a=function(c){return function(){a&&
(a=b=h.onload=h.onerror=h.onabort=h.onreadystatechange=null,"abort"===c?h.abort():"error"===c?"number"!==typeof h.status?g(0,"error"):g(h.status,h.statusText):g(Yb[h.status]||h.status,h.statusText,"text"!==(h.responseType||"text")||"string"!==typeof h.responseText?{binary:h.response}:{text:h.responseText},h.getAllResponseHeaders()))}};h.onload=a();b=h.onerror=a("error");h.onabort!==n?h.onabort=b:h.onreadystatechange=function(){4===h.readyState&&f.setTimeout(function(){a&&b()})};a=a("abort");try{h.send(c.hasContent&&
c.data||null)}catch(pb){if(a)throw pb;}},abort:function(){a&&a()}}});t.ajaxSetup({accepts:{script:"text/javascript, application/javascript, application/ecmascript, application/x-ecmascript"},contents:{script:/\b(?:java|ecma)script\b/},converters:{"text script":function(c){t.globalEval(c);return c}}});t.ajaxPrefilter("script",function(c){c.cache===n&&(c.cache=!1);c.crossDomain&&(c.type="GET")});t.ajaxTransport("script",function(c){if(c.crossDomain){var a,b;return{send:function(d,g){a=t("\x3cscript\x3e").prop({charset:c.scriptCharset,
src:c.url}).on("load error",b=function(c){a.remove();b=null;c&&g("error"===c.type?404:200,c.type)});I.head.appendChild(a[0])},abort:function(){b&&b()}}}});var lb=[],Sa=/(=)\?(?=&|$)|\?\?/;t.ajaxSetup({jsonp:"callback",jsonpCallback:function(){var c=lb.pop()||t.expando+"_"+Pa++;this[c]=!0;return c}});t.ajaxPrefilter("json jsonp",function(c,a,b){var d,g=!1!==c.jsonp&&(Sa.test(c.url)?"url":"string"===typeof c.data&&0===(c.contentType||"").indexOf("application/x-www-form-urlencoded")&&Sa.test(c.data)&&
"data");if(g||"jsonp"===c.dataTypes[0]){var p=c.jsonpCallback=t.isFunction(c.jsonpCallback)?c.jsonpCallback():c.jsonpCallback;g?c[g]=c[g].replace(Sa,"$1"+p):!1!==c.jsonp&&(c.url+=(Qa.test(c.url)?"\x26":"?")+c.jsonp+"\x3d"+p);c.converters["script json"]=function(){d||t.error(p+" was not called");return d[0]};c.dataTypes[0]="json";var h=f[p];f[p]=function(){d=arguments};b.always(function(){h===n?t(f).removeProp(p):f[p]=h;c[p]&&(c.jsonpCallback=a.jsonpCallback,lb.push(p));d&&t.isFunction(h)&&h(d[0]);
d=h=n});return"script"}});t.parseHTML=function(c,a,b){if(!c||"string"!==typeof c)return null;"boolean"===typeof a&&(b=a,a=!1);a=a||I;var d=bb.exec(c);b=!b&&[];if(d)return[a.createElement(d[1])];d=u([c],a,b);b&&b.length&&t(b).remove();return t.merge([],d.childNodes)};var mb=t.fn.load;t.fn.load=function(c,a,b){if("string"!==typeof c&&mb)return mb.apply(this,arguments);var d,g,p=this,h=c.indexOf(" ");if(-1<h){var e=t.trim(c.slice(h));c=c.slice(0,h)}t.isFunction(a)?(b=a,a=n):a&&"object"===typeof a&&(d=
"POST");0<p.length&&t.ajax({url:c,type:d||"GET",dataType:"html",data:a}).done(function(c){g=arguments;p.html(e?t("\x3cdiv\x3e").append(t.parseHTML(c)).find(e):c)}).always(b&&function(c,a){p.each(function(){b.apply(this,g||[c.responseText,a,c])})});return this};t.each("ajaxStart ajaxStop ajaxComplete ajaxError ajaxSuccess ajaxSend".split(" "),function(c,a){t.fn[a]=function(c){return this.on(a,c)}});t.expr.filters.animated=function(c){return t.grep(t.timers,function(a){return c===a.elem}).length};t.offset=
{setOffset:function(c,a,b){var d=t.css(c,"position"),g=t(c),p={};"static"===d&&(c.style.position="relative");var h=g.offset();var e=t.css(c,"top");var m=t.css(c,"left");("absolute"===d||"fixed"===d)&&-1<(e+m).indexOf("auto")?(m=g.position(),e=m.top,m=m.left):(e=parseFloat(e)||0,m=parseFloat(m)||0);t.isFunction(a)&&(a=a.call(c,b,t.extend({},h)));null!=a.top&&(p.top=a.top-h.top+e);null!=a.left&&(p.left=a.left-h.left+m);"using"in a?a.using.call(c,p):g.css(p)}};t.fn.extend({offset:function(c){if(arguments.length)return c===
n?this:this.each(function(a){t.offset.setOffset(this,c,a)});var a=this[0];var b={top:0,left:0},d=a&&a.ownerDocument;if(d){var g=d.documentElement;if(!t.contains(g,a))return b;b=a.getBoundingClientRect();a=aa(d);return{top:b.top+a.pageYOffset-g.clientTop,left:b.left+a.pageXOffset-g.clientLeft}}},position:function(){if(this[0]){var c=this[0],a={top:0,left:0};if("fixed"===t.css(c,"position"))var b=c.getBoundingClientRect();else{var d=this.offsetParent();b=this.offset();t.nodeName(d[0],"html")||(a=d.offset());
a.top+=t.css(d[0],"borderTopWidth",!0);a.left+=t.css(d[0],"borderLeftWidth",!0)}return{top:b.top-a.top-t.css(c,"marginTop",!0),left:b.left-a.left-t.css(c,"marginLeft",!0)}}},offsetParent:function(){return this.map(function(){for(var c=this.offsetParent;c&&"static"===t.css(c,"position");)c=c.offsetParent;return c||za})}});t.each({scrollLeft:"pageXOffset",scrollTop:"pageYOffset"},function(c,a){var b="pageYOffset"===a;t.fn[c]=function(d){return fa(this,function(c,d,g){var p=aa(c);if(g===n)return p?p[a]:
c[d];p?p.scrollTo(b?p.pageXOffset:g,b?g:p.pageYOffset):c[d]=g},c,d,arguments.length)}});t.each(["top","left"],function(c,a){t.cssHooks[a]=H(P.pixelPosition,function(c,b){if(b)return b=J(c,a),Ja.test(b)?t(c).position()[a]+"px":b})});t.each({Height:"height",Width:"width"},function(c,a){t.each({padding:"inner"+c,content:a,"":"outer"+c},function(b,d){t.fn[d]=function(d,g){var p=arguments.length&&(b||"boolean"!==typeof d),h=b||(!0===d||!0===g?"margin":"border");return fa(this,function(a,b,d){return t.isWindow(a)?
a.document.documentElement["client"+c]:9===a.nodeType?(b=a.documentElement,Math.max(a.body["scroll"+c],b["scroll"+c],a.body["offset"+c],b["offset"+c],b["client"+c])):d===n?t.css(a,b,h):t.style(a,b,d,h)},a,p?d:n,p,null)}})});t.fn.extend({bind:function(c,a,b){return this.on(c,null,a,b)},unbind:function(c,a){return this.off(c,null,a)},delegate:function(c,a,b,d){return this.on(a,c,b,d)},undelegate:function(c,a,b){return 1===arguments.length?this.off(c,"**"):this.off(a,c||"**",b)},size:function(){return this.length}});
t.fn.andSelf=t.fn.addBack;"function"===typeof define&&define.amd&&define("jquery",[],function(){return t});var Zb=f.jQuery,$b=f.$;t.noConflict=function(c){f.$===t&&(f.$=$b);c&&f.jQuery===t&&(f.jQuery=Zb);return t};e||(f.jQuery=f.$=t);return t});q.jQuery=jQuery;jQuery.noConflict(!0)})(window,ChemDoodle.lib);
(function(f){"function"===typeof define&&define.amd?define(["jquery"],f):"object"===typeof exports?module.exports=f:f(ChemDoodle.lib.jQuery)})(function(f){function q(g){var h=g||window.event,e=k.call(arguments,1),m=0,x=0,u=0,w=0;g=f.event.fix(h);g.type="mousewheel";"detail"in h&&(x=-1*h.detail);"wheelDelta"in h&&(x=h.wheelDelta);"wheelDeltaY"in h&&(x=h.wheelDeltaY);"wheelDeltaX"in h&&(m=-1*h.wheelDeltaX);"axis"in h&&h.axis===h.HORIZONTAL_AXIS&&(m=-1*x,x=0);var r=0===x?m:x;"deltaY"in h&&(r=x=-1*h.deltaY);
"deltaX"in h&&(m=h.deltaX,0===x&&(r=-1*m));if(0!==x||0!==m){if(1===h.deltaMode){var y=f.data(this,"mousewheel-line-height");r*=y;x*=y;m*=y}else 2===h.deltaMode&&(y=f.data(this,"mousewheel-page-height"),r*=y,x*=y,m*=y);y=Math.max(Math.abs(x),Math.abs(m));if(!d||y<d)d=y,a.settings.adjustOldDeltas&&"mousewheel"===h.type&&0===y%120&&(d/=40);a.settings.adjustOldDeltas&&"mousewheel"===h.type&&0===y%120&&(r/=40,m/=40,x/=40);r=Math[1<=r?"floor":"ceil"](r/d);m=Math[1<=m?"floor":"ceil"](m/d);x=Math[1<=x?"floor":
"ceil"](x/d);a.settings.normalizeOffset&&this.getBoundingClientRect&&(h=this.getBoundingClientRect(),u=g.clientX-h.left,w=g.clientY-h.top);g.deltaX=m;g.deltaY=x;g.deltaFactor=d;g.offsetX=u;g.offsetY=w;g.deltaMode=0;e.unshift(g,r,m,x);b&&clearTimeout(b);b=setTimeout(n,200);return(f.event.dispatch||f.event.handle).apply(this,e)}}function n(){d=null}var r=["wheel","mousewheel","DOMMouseScroll","MozMousePixelScroll"],e="onwheel"in document||9<=document.documentMode?["wheel"]:["mousewheel","DomMouseScroll",
"MozMousePixelScroll"],k=Array.prototype.slice,b,d;if(f.event.fixHooks)for(var h=r.length;h;)f.event.fixHooks[r[--h]]=f.event.mouseHooks;var a=f.event.special.mousewheel={version:"3.1.12",setup:function(){if(this.addEventListener)for(var b=e.length;b;)this.addEventListener(e[--b],q,!1);else this.onmousewheel=q;f.data(this,"mousewheel-line-height",a.getLineHeight(this));f.data(this,"mousewheel-page-height",a.getPageHeight(this))},teardown:function(){if(this.removeEventListener)for(var a=e.length;a;)this.removeEventListener(e[--a],
q,!1);else this.onmousewheel=null;f.removeData(this,"mousewheel-line-height");f.removeData(this,"mousewheel-page-height")},getLineHeight:function(a){a=f(a);var b=a["offsetParent"in f.fn?"offsetParent":"parent"]();b.length||(b=f("body"));return parseInt(b.css("fontSize"),10)||parseInt(a.css("fontSize"),10)||16},getPageHeight:function(a){return f(a).height()},settings:{adjustOldDeltas:!0,normalizeOffset:!0}};f.fn.extend({mousewheel:function(a){return a?this.bind("mousewheel",a):this.trigger("mousewheel")},
unmousewheel:function(a){return this.unbind("mousewheel",a)}})});
(function(f,q){"object"===typeof exports?module.exports=q(global):"function"===typeof define&&define.amd?define([],function(){return q(f)}):q(f)})(ChemDoodle.lib,function(f){function q(c){return e=c}function n(){return e="undefined"!==typeof Float32Array?Float32Array:Array}var r={};(function(){if("undefined"!=typeof Float32Array){var c=new Float32Array(1),a=new Int32Array(c.buffer);r.invsqrt=function(b){c[0]=b;a[0]=1597463007-(a[0]>>1);var d=c[0];return d*(1.5-.5*b*d*d)}}else r.invsqrt=function(c){return 1/
Math.sqrt(c)}})();var e=null;n();var k={create:function(c){var a=new e(3);c?(a[0]=c[0],a[1]=c[1],a[2]=c[2]):a[0]=a[1]=a[2]=0;return a},createFrom:function(c,a,b){var d=new e(3);d[0]=c;d[1]=a;d[2]=b;return d},set:function(c,a){a[0]=c[0];a[1]=c[1];a[2]=c[2];return a},equal:function(c,a){return c===a||1E-6>Math.abs(c[0]-a[0])&&1E-6>Math.abs(c[1]-a[1])&&1E-6>Math.abs(c[2]-a[2])},add:function(c,a,b){if(!b||c===b)return c[0]+=a[0],c[1]+=a[1],c[2]+=a[2],c;b[0]=c[0]+a[0];b[1]=c[1]+a[1];b[2]=c[2]+a[2];return b},
subtract:function(c,a,b){if(!b||c===b)return c[0]-=a[0],c[1]-=a[1],c[2]-=a[2],c;b[0]=c[0]-a[0];b[1]=c[1]-a[1];b[2]=c[2]-a[2];return b},multiply:function(c,a,b){if(!b||c===b)return c[0]*=a[0],c[1]*=a[1],c[2]*=a[2],c;b[0]=c[0]*a[0];b[1]=c[1]*a[1];b[2]=c[2]*a[2];return b},negate:function(c,a){a||(a=c);a[0]=-c[0];a[1]=-c[1];a[2]=-c[2];return a},scale:function(c,a,b){if(!b||c===b)return c[0]*=a,c[1]*=a,c[2]*=a,c;b[0]=c[0]*a;b[1]=c[1]*a;b[2]=c[2]*a;return b},normalize:function(c,a){a||(a=c);var b=c[0],
d=c[1];c=c[2];var g=Math.sqrt(b*b+d*d+c*c);if(!g)return a[0]=0,a[1]=0,a[2]=0,a;if(1===g)return a[0]=b,a[1]=d,a[2]=c,a;g=1/g;a[0]=b*g;a[1]=d*g;a[2]=c*g;return a},cross:function(c,a,b){b||(b=c);var d=c[0],g=c[1];c=c[2];var p=a[0],h=a[1];a=a[2];b[0]=g*a-c*h;b[1]=c*p-d*a;b[2]=d*h-g*p;return b},length:function(c){var a=c[0],b=c[1];c=c[2];return Math.sqrt(a*a+b*b+c*c)},squaredLength:function(c){var a=c[0],b=c[1];c=c[2];return a*a+b*b+c*c},dot:function(c,a){return c[0]*a[0]+c[1]*a[1]+c[2]*a[2]},direction:function(c,
a,b){b||(b=c);var d=c[0]-a[0],g=c[1]-a[1];c=c[2]-a[2];a=Math.sqrt(d*d+g*g+c*c);if(!a)return b[0]=0,b[1]=0,b[2]=0,b;a=1/a;b[0]=d*a;b[1]=g*a;b[2]=c*a;return b},lerp:function(c,a,b,d){d||(d=c);d[0]=c[0]+b*(a[0]-c[0]);d[1]=c[1]+b*(a[1]-c[1]);d[2]=c[2]+b*(a[2]-c[2]);return d},dist:function(c,a){var b=a[0]-c[0],d=a[1]-c[1];c=a[2]-c[2];return Math.sqrt(b*b+d*d+c*c)}},b=null,d=new e(4);k.unproject=function(c,a,g,h,e){e||(e=c);b||(b=m.create());var p=b;d[0]=2*(c[0]-h[0])/h[2]-1;d[1]=2*(c[1]-h[1])/h[3]-1;d[2]=
2*c[2]-1;d[3]=1;m.multiply(g,a,p);if(!m.inverse(p))return null;m.multiplyVec4(p,d);if(0===d[3])return null;e[0]=d[0]/d[3];e[1]=d[1]/d[3];e[2]=d[2]/d[3];return e};var h=k.createFrom(1,0,0),a=k.createFrom(0,1,0),g=k.createFrom(0,0,1),l=k.create();k.rotationTo=function(c,b,d){d||(d=x.create());var p=k.dot(c,b);if(1<=p)x.set(u,d);else if(-.999999>p)k.cross(h,c,l),1E-6>k.length(l)&&k.cross(a,c,l),1E-6>k.length(l)&&k.cross(g,c,l),k.normalize(l),x.fromAngleAxis(Math.PI,l,d);else{p=Math.sqrt(2*(1+p));var e=
1/p;k.cross(c,b,l);d[0]=l[0]*e;d[1]=l[1]*e;d[2]=l[2]*e;d[3]=.5*p;x.normalize(d)}1<d[3]?d[3]=1:-1>d[3]&&(d[3]=-1);return d};k.str=function(c){return"["+c[0]+", "+c[1]+", "+c[2]+"]"};var v={create:function(c){var a=new e(9);c?(a[0]=c[0],a[1]=c[1],a[2]=c[2],a[3]=c[3],a[4]=c[4],a[5]=c[5],a[6]=c[6],a[7]=c[7],a[8]=c[8]):a[0]=a[1]=a[2]=a[3]=a[4]=a[5]=a[6]=a[7]=a[8]=0;return a},createFrom:function(c,a,b,d,g,h,m,l,v){var p=new e(9);p[0]=c;p[1]=a;p[2]=b;p[3]=d;p[4]=g;p[5]=h;p[6]=m;p[7]=l;p[8]=v;return p},determinant:function(c){var a=
c[3],b=c[4],d=c[5],g=c[6],h=c[7],e=c[8];return c[0]*(e*b-d*h)+c[1]*(-e*a+d*g)+c[2]*(h*a-b*g)},inverse:function(c,a){var b=c[0],d=c[1],g=c[2],h=c[3],p=c[4],e=c[5],m=c[6],l=c[7];c=c[8];var f=c*p-e*l,k=-c*h+e*m,x=l*h-p*m,u=b*f+d*k+g*x;if(!u)return null;u=1/u;a||(a=v.create());a[0]=f*u;a[1]=(-c*d+g*l)*u;a[2]=(e*d-g*p)*u;a[3]=k*u;a[4]=(c*b-g*m)*u;a[5]=(-e*b+g*h)*u;a[6]=x*u;a[7]=(-l*b+d*m)*u;a[8]=(p*b-d*h)*u;return a},multiply:function(c,a,b){b||(b=c);var d=c[0],g=c[1],h=c[2],p=c[3],e=c[4],m=c[5],l=c[6],
v=c[7];c=c[8];var f=a[0],k=a[1],x=a[2],u=a[3],w=a[4],A=a[5],r=a[6],n=a[7];a=a[8];b[0]=f*d+k*p+x*l;b[1]=f*g+k*e+x*v;b[2]=f*h+k*m+x*c;b[3]=u*d+w*p+A*l;b[4]=u*g+w*e+A*v;b[5]=u*h+w*m+A*c;b[6]=r*d+n*p+a*l;b[7]=r*g+n*e+a*v;b[8]=r*h+n*m+a*c;return b},multiplyVec2:function(c,a,b){b||(b=a);var d=a[0];a=a[1];b[0]=d*c[0]+a*c[3]+c[6];b[1]=d*c[1]+a*c[4]+c[7];return b},multiplyVec3:function(c,a,b){b||(b=a);var d=a[0],g=a[1];a=a[2];b[0]=d*c[0]+g*c[3]+a*c[6];b[1]=d*c[1]+g*c[4]+a*c[7];b[2]=d*c[2]+g*c[5]+a*c[8];return b},
set:function(c,a){a[0]=c[0];a[1]=c[1];a[2]=c[2];a[3]=c[3];a[4]=c[4];a[5]=c[5];a[6]=c[6];a[7]=c[7];a[8]=c[8];return a},equal:function(c,a){return c===a||1E-6>Math.abs(c[0]-a[0])&&1E-6>Math.abs(c[1]-a[1])&&1E-6>Math.abs(c[2]-a[2])&&1E-6>Math.abs(c[3]-a[3])&&1E-6>Math.abs(c[4]-a[4])&&1E-6>Math.abs(c[5]-a[5])&&1E-6>Math.abs(c[6]-a[6])&&1E-6>Math.abs(c[7]-a[7])&&1E-6>Math.abs(c[8]-a[8])},identity:function(c){c||(c=v.create());c[0]=1;c[1]=0;c[2]=0;c[3]=0;c[4]=1;c[5]=0;c[6]=0;c[7]=0;c[8]=1;return c},transpose:function(c,
a){if(!a||c===a){a=c[1];var b=c[2],d=c[5];c[1]=c[3];c[2]=c[6];c[3]=a;c[5]=c[7];c[6]=b;c[7]=d;return c}a[0]=c[0];a[1]=c[3];a[2]=c[6];a[3]=c[1];a[4]=c[4];a[5]=c[7];a[6]=c[2];a[7]=c[5];a[8]=c[8];return a},toMat4:function(c,a){a||(a=m.create());a[15]=1;a[14]=0;a[13]=0;a[12]=0;a[11]=0;a[10]=c[8];a[9]=c[7];a[8]=c[6];a[7]=0;a[6]=c[5];a[5]=c[4];a[4]=c[3];a[3]=0;a[2]=c[2];a[1]=c[1];a[0]=c[0];return a},str:function(c){return"["+c[0]+", "+c[1]+", "+c[2]+", "+c[3]+", "+c[4]+", "+c[5]+", "+c[6]+", "+c[7]+", "+
c[8]+"]"}},m={create:function(c){var a=new e(16);c&&(a[0]=c[0],a[1]=c[1],a[2]=c[2],a[3]=c[3],a[4]=c[4],a[5]=c[5],a[6]=c[6],a[7]=c[7],a[8]=c[8],a[9]=c[9],a[10]=c[10],a[11]=c[11],a[12]=c[12],a[13]=c[13],a[14]=c[14],a[15]=c[15]);return a},createFrom:function(c,a,b,d,g,h,m,l,v,f,k,x,u,w,r,n){var p=new e(16);p[0]=c;p[1]=a;p[2]=b;p[3]=d;p[4]=g;p[5]=h;p[6]=m;p[7]=l;p[8]=v;p[9]=f;p[10]=k;p[11]=x;p[12]=u;p[13]=w;p[14]=r;p[15]=n;return p},set:function(c,a){a[0]=c[0];a[1]=c[1];a[2]=c[2];a[3]=c[3];a[4]=c[4];
a[5]=c[5];a[6]=c[6];a[7]=c[7];a[8]=c[8];a[9]=c[9];a[10]=c[10];a[11]=c[11];a[12]=c[12];a[13]=c[13];a[14]=c[14];a[15]=c[15];return a},equal:function(c,a){return c===a||1E-6>Math.abs(c[0]-a[0])&&1E-6>Math.abs(c[1]-a[1])&&1E-6>Math.abs(c[2]-a[2])&&1E-6>Math.abs(c[3]-a[3])&&1E-6>Math.abs(c[4]-a[4])&&1E-6>Math.abs(c[5]-a[5])&&1E-6>Math.abs(c[6]-a[6])&&1E-6>Math.abs(c[7]-a[7])&&1E-6>Math.abs(c[8]-a[8])&&1E-6>Math.abs(c[9]-a[9])&&1E-6>Math.abs(c[10]-a[10])&&1E-6>Math.abs(c[11]-a[11])&&1E-6>Math.abs(c[12]-
a[12])&&1E-6>Math.abs(c[13]-a[13])&&1E-6>Math.abs(c[14]-a[14])&&1E-6>Math.abs(c[15]-a[15])},identity:function(c){c||(c=m.create());c[0]=1;c[1]=0;c[2]=0;c[3]=0;c[4]=0;c[5]=1;c[6]=0;c[7]=0;c[8]=0;c[9]=0;c[10]=1;c[11]=0;c[12]=0;c[13]=0;c[14]=0;c[15]=1;return c},transpose:function(c,a){if(!a||c===a){a=c[1];var b=c[2],d=c[3],g=c[6],h=c[7],p=c[11];c[1]=c[4];c[2]=c[8];c[3]=c[12];c[4]=a;c[6]=c[9];c[7]=c[13];c[8]=b;c[9]=g;c[11]=c[14];c[12]=d;c[13]=h;c[14]=p;return c}a[0]=c[0];a[1]=c[4];a[2]=c[8];a[3]=c[12];
a[4]=c[1];a[5]=c[5];a[6]=c[9];a[7]=c[13];a[8]=c[2];a[9]=c[6];a[10]=c[10];a[11]=c[14];a[12]=c[3];a[13]=c[7];a[14]=c[11];a[15]=c[15];return a},determinant:function(c){var a=c[0],b=c[1],d=c[2],g=c[3],h=c[4],e=c[5],m=c[6],l=c[7],v=c[8],f=c[9],k=c[10],x=c[11],u=c[12],w=c[13],r=c[14];c=c[15];return u*f*m*g-v*w*m*g-u*e*k*g+h*w*k*g+v*e*r*g-h*f*r*g-u*f*d*l+v*w*d*l+u*b*k*l-a*w*k*l-v*b*r*l+a*f*r*l+u*e*d*x-h*w*d*x-u*b*m*x+a*w*m*x+h*b*r*x-a*e*r*x-v*e*d*c+h*f*d*c+v*b*m*c-a*f*m*c-h*b*k*c+a*e*k*c},inverse:function(c,
a){a||(a=c);var b=c[0],d=c[1],g=c[2],h=c[3],e=c[4],p=c[5],m=c[6],l=c[7],v=c[8],f=c[9],k=c[10],x=c[11],u=c[12],w=c[13],r=c[14];c=c[15];var n=b*p-d*e,z=b*m-g*e,y=b*l-h*e,q=d*m-g*p,V=d*l-h*p,Y=g*l-h*m,T=v*w-f*u,R=v*r-k*u,N=v*c-x*u,S=f*r-k*w,aa=f*c-x*w,Z=k*c-x*r,I=n*Z-z*aa+y*S+q*N-V*R+Y*T;if(!I)return null;I=1/I;a[0]=(p*Z-m*aa+l*S)*I;a[1]=(-d*Z+g*aa-h*S)*I;a[2]=(w*Y-r*V+c*q)*I;a[3]=(-f*Y+k*V-x*q)*I;a[4]=(-e*Z+m*N-l*R)*I;a[5]=(b*Z-g*N+h*R)*I;a[6]=(-u*Y+r*y-c*z)*I;a[7]=(v*Y-k*y+x*z)*I;a[8]=(e*aa-p*N+l*
T)*I;a[9]=(-b*aa+d*N-h*T)*I;a[10]=(u*V-w*y+c*n)*I;a[11]=(-v*V+f*y-x*n)*I;a[12]=(-e*S+p*R-m*T)*I;a[13]=(b*S-d*R+g*T)*I;a[14]=(-u*q+w*z-r*n)*I;a[15]=(v*q-f*z+k*n)*I;return a},toRotationMat:function(c,a){a||(a=m.create());a[0]=c[0];a[1]=c[1];a[2]=c[2];a[3]=c[3];a[4]=c[4];a[5]=c[5];a[6]=c[6];a[7]=c[7];a[8]=c[8];a[9]=c[9];a[10]=c[10];a[11]=c[11];a[12]=0;a[13]=0;a[14]=0;a[15]=1;return a},toMat3:function(c,a){a||(a=v.create());a[0]=c[0];a[1]=c[1];a[2]=c[2];a[3]=c[4];a[4]=c[5];a[5]=c[6];a[6]=c[8];a[7]=c[9];
a[8]=c[10];return a},toInverseMat3:function(c,a){var b=c[0],d=c[1],g=c[2],h=c[4],e=c[5],p=c[6],m=c[8],l=c[9];c=c[10];var f=c*e-p*l,k=-c*h+p*m,x=l*h-e*m,u=b*f+d*k+g*x;if(!u)return null;u=1/u;a||(a=v.create());a[0]=f*u;a[1]=(-c*d+g*l)*u;a[2]=(p*d-g*e)*u;a[3]=k*u;a[4]=(c*b-g*m)*u;a[5]=(-p*b+g*h)*u;a[6]=x*u;a[7]=(-l*b+d*m)*u;a[8]=(e*b-d*h)*u;return a},multiply:function(c,a,b){b||(b=c);var d=c[0],g=c[1],h=c[2],e=c[3],m=c[4],p=c[5],l=c[6],v=c[7],f=c[8],k=c[9],x=c[10],u=c[11],w=c[12],r=c[13],A=c[14];c=c[15];
var n=a[0],z=a[1],y=a[2],q=a[3];b[0]=n*d+z*m+y*f+q*w;b[1]=n*g+z*p+y*k+q*r;b[2]=n*h+z*l+y*x+q*A;b[3]=n*e+z*v+y*u+q*c;n=a[4];z=a[5];y=a[6];q=a[7];b[4]=n*d+z*m+y*f+q*w;b[5]=n*g+z*p+y*k+q*r;b[6]=n*h+z*l+y*x+q*A;b[7]=n*e+z*v+y*u+q*c;n=a[8];z=a[9];y=a[10];q=a[11];b[8]=n*d+z*m+y*f+q*w;b[9]=n*g+z*p+y*k+q*r;b[10]=n*h+z*l+y*x+q*A;b[11]=n*e+z*v+y*u+q*c;n=a[12];z=a[13];y=a[14];q=a[15];b[12]=n*d+z*m+y*f+q*w;b[13]=n*g+z*p+y*k+q*r;b[14]=n*h+z*l+y*x+q*A;b[15]=n*e+z*v+y*u+q*c;return b},multiplyVec3:function(c,a,b){b||
(b=a);var d=a[0],g=a[1];a=a[2];b[0]=c[0]*d+c[4]*g+c[8]*a+c[12];b[1]=c[1]*d+c[5]*g+c[9]*a+c[13];b[2]=c[2]*d+c[6]*g+c[10]*a+c[14];return b},multiplyVec4:function(c,a,b){b||(b=a);var d=a[0],g=a[1],h=a[2];a=a[3];b[0]=c[0]*d+c[4]*g+c[8]*h+c[12]*a;b[1]=c[1]*d+c[5]*g+c[9]*h+c[13]*a;b[2]=c[2]*d+c[6]*g+c[10]*h+c[14]*a;b[3]=c[3]*d+c[7]*g+c[11]*h+c[15]*a;return b},translate:function(c,a,b){var d=a[0],g=a[1];a=a[2];if(!b||c===b)return c[12]=c[0]*d+c[4]*g+c[8]*a+c[12],c[13]=c[1]*d+c[5]*g+c[9]*a+c[13],c[14]=c[2]*
d+c[6]*g+c[10]*a+c[14],c[15]=c[3]*d+c[7]*g+c[11]*a+c[15],c;var h=c[0];var e=c[1];var m=c[2];var p=c[3];var l=c[4];var v=c[5];var f=c[6];var k=c[7];var x=c[8];var u=c[9];var w=c[10];var r=c[11];b[0]=h;b[1]=e;b[2]=m;b[3]=p;b[4]=l;b[5]=v;b[6]=f;b[7]=k;b[8]=x;b[9]=u;b[10]=w;b[11]=r;b[12]=h*d+l*g+x*a+c[12];b[13]=e*d+v*g+u*a+c[13];b[14]=m*d+f*g+w*a+c[14];b[15]=p*d+k*g+r*a+c[15];return b},scale:function(c,a,b){var d=a[0],g=a[1];a=a[2];if(!b||c===b)return c[0]*=d,c[1]*=d,c[2]*=d,c[3]*=d,c[4]*=g,c[5]*=g,c[6]*=
g,c[7]*=g,c[8]*=a,c[9]*=a,c[10]*=a,c[11]*=a,c;b[0]=c[0]*d;b[1]=c[1]*d;b[2]=c[2]*d;b[3]=c[3]*d;b[4]=c[4]*g;b[5]=c[5]*g;b[6]=c[6]*g;b[7]=c[7]*g;b[8]=c[8]*a;b[9]=c[9]*a;b[10]=c[10]*a;b[11]=c[11]*a;b[12]=c[12];b[13]=c[13];b[14]=c[14];b[15]=c[15];return b},rotate:function(c,a,b,d){var g=b[0],h=b[1];b=b[2];var e=Math.sqrt(g*g+h*h+b*b);if(!e)return null;1!==e&&(e=1/e,g*=e,h*=e,b*=e);var m=Math.sin(a);var l=Math.cos(a);var p=1-l;a=c[0];e=c[1];var v=c[2];var f=c[3];var k=c[4];var x=c[5];var u=c[6];var w=c[7];
var r=c[8];var n=c[9];var A=c[10];var z=c[11];var y=g*g*p+l;var q=h*g*p+b*m;var C=b*g*p-h*m;var T=g*h*p-b*m;var R=h*h*p+l;var N=b*h*p+g*m;var S=g*b*p+h*m;g=h*b*p-g*m;h=b*b*p+l;d?c!==d&&(d[12]=c[12],d[13]=c[13],d[14]=c[14],d[15]=c[15]):d=c;d[0]=a*y+k*q+r*C;d[1]=e*y+x*q+n*C;d[2]=v*y+u*q+A*C;d[3]=f*y+w*q+z*C;d[4]=a*T+k*R+r*N;d[5]=e*T+x*R+n*N;d[6]=v*T+u*R+A*N;d[7]=f*T+w*R+z*N;d[8]=a*S+k*g+r*h;d[9]=e*S+x*g+n*h;d[10]=v*S+u*g+A*h;d[11]=f*S+w*g+z*h;return d},rotateX:function(c,a,b){var d=Math.sin(a);a=Math.cos(a);
var g=c[4],h=c[5],e=c[6],m=c[7],l=c[8],p=c[9],v=c[10],f=c[11];b?c!==b&&(b[0]=c[0],b[1]=c[1],b[2]=c[2],b[3]=c[3],b[12]=c[12],b[13]=c[13],b[14]=c[14],b[15]=c[15]):b=c;b[4]=g*a+l*d;b[5]=h*a+p*d;b[6]=e*a+v*d;b[7]=m*a+f*d;b[8]=g*-d+l*a;b[9]=h*-d+p*a;b[10]=e*-d+v*a;b[11]=m*-d+f*a;return b},rotateY:function(c,a,b){var d=Math.sin(a);a=Math.cos(a);var g=c[0],h=c[1],e=c[2],m=c[3],l=c[8],p=c[9],v=c[10],f=c[11];b?c!==b&&(b[4]=c[4],b[5]=c[5],b[6]=c[6],b[7]=c[7],b[12]=c[12],b[13]=c[13],b[14]=c[14],b[15]=c[15]):
b=c;b[0]=g*a+l*-d;b[1]=h*a+p*-d;b[2]=e*a+v*-d;b[3]=m*a+f*-d;b[8]=g*d+l*a;b[9]=h*d+p*a;b[10]=e*d+v*a;b[11]=m*d+f*a;return b},rotateZ:function(c,a,b){var d=Math.sin(a);a=Math.cos(a);var g=c[0],h=c[1],e=c[2],m=c[3],l=c[4],p=c[5],v=c[6],f=c[7];b?c!==b&&(b[8]=c[8],b[9]=c[9],b[10]=c[10],b[11]=c[11],b[12]=c[12],b[13]=c[13],b[14]=c[14],b[15]=c[15]):b=c;b[0]=g*a+l*d;b[1]=h*a+p*d;b[2]=e*a+v*d;b[3]=m*a+f*d;b[4]=g*-d+l*a;b[5]=h*-d+p*a;b[6]=e*-d+v*a;b[7]=m*-d+f*a;return b},frustum:function(c,a,b,d,g,h,e){e||(e=
m.create());var l=a-c,p=d-b,v=h-g;e[0]=2*g/l;e[1]=0;e[2]=0;e[3]=0;e[4]=0;e[5]=2*g/p;e[6]=0;e[7]=0;e[8]=(a+c)/l;e[9]=(d+b)/p;e[10]=-(h+g)/v;e[11]=-1;e[12]=0;e[13]=0;e[14]=-(h*g*2)/v;e[15]=0;return e},perspective:function(c,a,b,d,g){c=b*Math.tan(c*Math.PI/360);a*=c;return m.frustum(-a,a,-c,c,b,d,g)},ortho:function(c,a,b,d,g,h,e){e||(e=m.create());var l=a-c,p=d-b,v=h-g;e[0]=2/l;e[1]=0;e[2]=0;e[3]=0;e[4]=0;e[5]=2/p;e[6]=0;e[7]=0;e[8]=0;e[9]=0;e[10]=-2/v;e[11]=0;e[12]=-(c+a)/l;e[13]=-(d+b)/p;e[14]=-(h+
g)/v;e[15]=1;return e},lookAt:function(c,a,b,d){d||(d=m.create());var g=c[0],h=c[1];c=c[2];var e=b[0];var l=b[1];var p=b[2];var v=a[0];b=a[1];var f=a[2];if(g===v&&h===b&&c===f)return m.identity(d);a=g-v;b=h-b;v=c-f;var k=1/Math.sqrt(a*a+b*b+v*v);a*=k;b*=k;v*=k;f=l*v-p*b;p=p*a-e*v;e=e*b-l*a;(k=Math.sqrt(f*f+p*p+e*e))?(k=1/k,f*=k,p*=k,e*=k):e=p=f=0;l=b*e-v*p;var x=v*f-a*e;var u=a*p-b*f;(k=Math.sqrt(l*l+x*x+u*u))?(k=1/k,l*=k,x*=k,u*=k):u=x=l=0;d[0]=f;d[1]=l;d[2]=a;d[3]=0;d[4]=p;d[5]=x;d[6]=b;d[7]=0;
d[8]=e;d[9]=u;d[10]=v;d[11]=0;d[12]=-(f*g+p*h+e*c);d[13]=-(l*g+x*h+u*c);d[14]=-(a*g+b*h+v*c);d[15]=1;return d},fromRotationTranslation:function(c,a,b){b||(b=m.create());var d=c[0],g=c[1],h=c[2],e=c[3],l=d+d,p=g+g,v=h+h;c=d*l;var f=d*p;d*=v;var k=g*p;g*=v;h*=v;l*=e;p*=e;e*=v;b[0]=1-(k+h);b[1]=f+e;b[2]=d-p;b[3]=0;b[4]=f-e;b[5]=1-(c+h);b[6]=g+l;b[7]=0;b[8]=d+p;b[9]=g-l;b[10]=1-(c+k);b[11]=0;b[12]=a[0];b[13]=a[1];b[14]=a[2];b[15]=1;return b},str:function(c){return"["+c[0]+", "+c[1]+", "+c[2]+", "+c[3]+
", "+c[4]+", "+c[5]+", "+c[6]+", "+c[7]+", "+c[8]+", "+c[9]+", "+c[10]+", "+c[11]+", "+c[12]+", "+c[13]+", "+c[14]+", "+c[15]+"]"}},x={create:function(c){var a=new e(4);c?(a[0]=c[0],a[1]=c[1],a[2]=c[2],a[3]=c[3]):a[0]=a[1]=a[2]=a[3]=0;return a},createFrom:function(c,a,b,d){var g=new e(4);g[0]=c;g[1]=a;g[2]=b;g[3]=d;return g},set:function(c,a){a[0]=c[0];a[1]=c[1];a[2]=c[2];a[3]=c[3];return a},equal:function(c,a){return c===a||1E-6>Math.abs(c[0]-a[0])&&1E-6>Math.abs(c[1]-a[1])&&1E-6>Math.abs(c[2]-a[2])&&
1E-6>Math.abs(c[3]-a[3])},identity:function(c){c||(c=x.create());c[0]=0;c[1]=0;c[2]=0;c[3]=1;return c}},u=x.identity();x.calculateW=function(c,a){var b=c[0],d=c[1],g=c[2];if(!a||c===a)return c[3]=-Math.sqrt(Math.abs(1-b*b-d*d-g*g)),c;a[0]=b;a[1]=d;a[2]=g;a[3]=-Math.sqrt(Math.abs(1-b*b-d*d-g*g));return a};x.dot=function(c,a){return c[0]*a[0]+c[1]*a[1]+c[2]*a[2]+c[3]*a[3]};x.inverse=function(c,a){var b=c[0],d=c[1],g=c[2],h=c[3];b=(b=b*b+d*d+g*g+h*h)?1/b:0;if(!a||c===a)return c[0]*=-b,c[1]*=-b,c[2]*=
-b,c[3]*=b,c;a[0]=-c[0]*b;a[1]=-c[1]*b;a[2]=-c[2]*b;a[3]=c[3]*b;return a};x.conjugate=function(c,a){if(!a||c===a)return c[0]*=-1,c[1]*=-1,c[2]*=-1,c;a[0]=-c[0];a[1]=-c[1];a[2]=-c[2];a[3]=c[3];return a};x.length=function(c){var a=c[0],b=c[1],d=c[2];c=c[3];return Math.sqrt(a*a+b*b+d*d+c*c)};x.normalize=function(c,a){a||(a=c);var b=c[0],d=c[1],g=c[2];c=c[3];var h=Math.sqrt(b*b+d*d+g*g+c*c);if(0===h)return a[0]=0,a[1]=0,a[2]=0,a[3]=0,a;h=1/h;a[0]=b*h;a[1]=d*h;a[2]=g*h;a[3]=c*h;return a};x.add=function(c,
a,b){if(!b||c===b)return c[0]+=a[0],c[1]+=a[1],c[2]+=a[2],c[3]+=a[3],c;b[0]=c[0]+a[0];b[1]=c[1]+a[1];b[2]=c[2]+a[2];b[3]=c[3]+a[3];return b};x.multiply=function(c,a,b){b||(b=c);var d=c[0],g=c[1],h=c[2];c=c[3];var e=a[0],m=a[1],l=a[2];a=a[3];b[0]=d*a+c*e+g*l-h*m;b[1]=g*a+c*m+h*e-d*l;b[2]=h*a+c*l+d*m-g*e;b[3]=c*a-d*e-g*m-h*l;return b};x.multiplyVec3=function(c,a,b){b||(b=a);var d=a[0],g=a[1],h=a[2];a=c[0];var e=c[1],m=c[2];c=c[3];var l=c*d+e*h-m*g,p=c*g+m*d-a*h,v=c*h+a*g-e*d;d=-a*d-e*g-m*h;b[0]=l*c+
d*-a+p*-m-v*-e;b[1]=p*c+d*-e+v*-a-l*-m;b[2]=v*c+d*-m+l*-e-p*-a;return b};x.scale=function(c,a,b){if(!b||c===b)return c[0]*=a,c[1]*=a,c[2]*=a,c[3]*=a,c;b[0]=c[0]*a;b[1]=c[1]*a;b[2]=c[2]*a;b[3]=c[3]*a;return b};x.toMat3=function(c,a){a||(a=v.create());var b=c[0],d=c[1],g=c[2],h=c[3],e=b+b,m=d+d,l=g+g;c=b*e;var p=b*m;b*=l;var f=d*m;d*=l;g*=l;e*=h;m*=h;h*=l;a[0]=1-(f+g);a[1]=p+h;a[2]=b-m;a[3]=p-h;a[4]=1-(c+g);a[5]=d+e;a[6]=b+m;a[7]=d-e;a[8]=1-(c+f);return a};x.toMat4=function(c,a){a||(a=m.create());var b=
c[0],d=c[1],g=c[2],h=c[3],e=b+b,l=d+d,p=g+g;c=b*e;var v=b*l;b*=p;var f=d*l;d*=p;g*=p;e*=h;l*=h;h*=p;a[0]=1-(f+g);a[1]=v+h;a[2]=b-l;a[3]=0;a[4]=v-h;a[5]=1-(c+g);a[6]=d+e;a[7]=0;a[8]=b+l;a[9]=d-e;a[10]=1-(c+f);a[11]=0;a[12]=0;a[13]=0;a[14]=0;a[15]=1;return a};x.slerp=function(a,b,d,g){g||(g=a);var c=a[0]*b[0]+a[1]*b[1]+a[2]*b[2]+a[3]*b[3];if(1<=Math.abs(c))return g!==a&&(g[0]=a[0],g[1]=a[1],g[2]=a[2],g[3]=a[3]),g;var h=Math.acos(c);var e=Math.sqrt(1-c*c);if(.001>Math.abs(e))return g[0]=.5*a[0]+.5*b[0],
g[1]=.5*a[1]+.5*b[1],g[2]=.5*a[2]+.5*b[2],g[3]=.5*a[3]+.5*b[3],g;c=Math.sin((1-d)*h)/e;d=Math.sin(d*h)/e;g[0]=a[0]*c+b[0]*d;g[1]=a[1]*c+b[1]*d;g[2]=a[2]*c+b[2]*d;g[3]=a[3]*c+b[3]*d;return g};x.fromRotationMatrix=function(a,b){b||(b=x.create());var c=a[0]+a[4]+a[8];if(0<c){var d=Math.sqrt(c+1);b[3]=.5*d;d=.5/d;b[0]=(a[7]-a[5])*d;b[1]=(a[2]-a[6])*d;b[2]=(a[3]-a[1])*d}else{d=x.fromRotationMatrix.s_iNext=x.fromRotationMatrix.s_iNext||[1,2,0];c=0;a[4]>a[0]&&(c=1);a[8]>a[3*c+c]&&(c=2);var g=d[c],h=d[g];
d=Math.sqrt(a[3*c+c]-a[3*g+g]-a[3*h+h]+1);b[c]=.5*d;d=.5/d;b[3]=(a[3*h+g]-a[3*g+h])*d;b[g]=(a[3*g+c]+a[3*c+g])*d;b[h]=(a[3*h+c]+a[3*c+h])*d}return b};v.toQuat4=x.fromRotationMatrix;(function(){var a=v.create();x.fromAxes=function(c,b,d,g){a[0]=b[0];a[3]=b[1];a[6]=b[2];a[1]=d[0];a[4]=d[1];a[7]=d[2];a[2]=c[0];a[5]=c[1];a[8]=c[2];return x.fromRotationMatrix(a,g)}})();x.identity=function(a){a||(a=x.create());a[0]=0;a[1]=0;a[2]=0;a[3]=1;return a};x.fromAngleAxis=function(a,b,d){d||(d=x.create());a*=.5;
var c=Math.sin(a);d[3]=Math.cos(a);d[0]=c*b[0];d[1]=c*b[1];d[2]=c*b[2];return d};x.toAngleAxis=function(a,b){b||(b=a);var c=a[0]*a[0]+a[1]*a[1]+a[2]*a[2];0<c?(b[3]=2*Math.acos(a[3]),c=r.invsqrt(c),b[0]=a[0]*c,b[1]=a[1]*c,b[2]=a[2]*c):(b[3]=0,b[0]=1,b[1]=0,b[2]=0);return b};x.str=function(a){return"["+a[0]+", "+a[1]+", "+a[2]+", "+a[3]+"]"};var w={create:function(a){var c=new e(2);a?(c[0]=a[0],c[1]=a[1]):(c[0]=0,c[1]=0);return c},createFrom:function(a,b){var c=new e(2);c[0]=a;c[1]=b;return c},add:function(a,
b,d){d||(d=b);d[0]=a[0]+b[0];d[1]=a[1]+b[1];return d},subtract:function(a,b,d){d||(d=b);d[0]=a[0]-b[0];d[1]=a[1]-b[1];return d},multiply:function(a,b,d){d||(d=b);d[0]=a[0]*b[0];d[1]=a[1]*b[1];return d},divide:function(a,b,d){d||(d=b);d[0]=a[0]/b[0];d[1]=a[1]/b[1];return d},scale:function(a,b,d){d||(d=a);d[0]=a[0]*b;d[1]=a[1]*b;return d},dist:function(a,b){var c=b[0]-a[0];a=b[1]-a[1];return Math.sqrt(c*c+a*a)},set:function(a,b){b[0]=a[0];b[1]=a[1];return b},equal:function(a,b){return a===b||1E-6>Math.abs(a[0]-
b[0])&&1E-6>Math.abs(a[1]-b[1])},negate:function(a,b){b||(b=a);b[0]=-a[0];b[1]=-a[1];return b},normalize:function(a,b){b||(b=a);var c=a[0]*a[0]+a[1]*a[1];0<c?(c=Math.sqrt(c),b[0]=a[0]/c,b[1]=a[1]/c):b[0]=b[1]=0;return b},cross:function(a,b,d){a=a[0]*b[1]-a[1]*b[0];if(!d)return a;d[0]=d[1]=0;d[2]=a;return d},length:function(a){var c=a[0];a=a[1];return Math.sqrt(c*c+a*a)},squaredLength:function(a){var c=a[0];a=a[1];return c*c+a*a},dot:function(a,b){return a[0]*b[0]+a[1]*b[1]},direction:function(a,b,
d){d||(d=a);var c=a[0]-b[0];a=a[1]-b[1];b=c*c+a*a;if(!b)return d[0]=0,d[1]=0,d[2]=0,d;b=1/Math.sqrt(b);d[0]=c*b;d[1]=a*b;return d},lerp:function(a,b,d,g){g||(g=a);g[0]=a[0]+d*(b[0]-a[0]);g[1]=a[1]+d*(b[1]-a[1]);return g},str:function(a){return"["+a[0]+", "+a[1]+"]"}},z={create:function(a){var c=new e(4);a?(c[0]=a[0],c[1]=a[1],c[2]=a[2],c[3]=a[3]):c[0]=c[1]=c[2]=c[3]=0;return c},createFrom:function(a,b,d,g){var c=new e(4);c[0]=a;c[1]=b;c[2]=d;c[3]=g;return c},set:function(a,b){b[0]=a[0];b[1]=a[1];
b[2]=a[2];b[3]=a[3];return b},equal:function(a,b){return a===b||1E-6>Math.abs(a[0]-b[0])&&1E-6>Math.abs(a[1]-b[1])&&1E-6>Math.abs(a[2]-b[2])&&1E-6>Math.abs(a[3]-b[3])},identity:function(a){a||(a=z.create());a[0]=1;a[1]=0;a[2]=0;a[3]=1;return a},transpose:function(a,b){if(!b||a===b)return b=a[1],a[1]=a[2],a[2]=b,a;b[0]=a[0];b[1]=a[2];b[2]=a[1];b[3]=a[3];return b},determinant:function(a){return a[0]*a[3]-a[2]*a[1]},inverse:function(a,b){b||(b=a);var c=a[0],d=a[1],g=a[2];a=a[3];var h=c*a-g*d;if(!h)return null;
h=1/h;b[0]=a*h;b[1]=-d*h;b[2]=-g*h;b[3]=c*h;return b},multiply:function(a,b,d){d||(d=a);var c=a[0],g=a[1],h=a[2];a=a[3];d[0]=c*b[0]+g*b[2];d[1]=c*b[1]+g*b[3];d[2]=h*b[0]+a*b[2];d[3]=h*b[1]+a*b[3];return d},rotate:function(a,b,d){d||(d=a);var c=a[0],g=a[1],h=a[2];a=a[3];var e=Math.sin(b);b=Math.cos(b);d[0]=c*b+g*e;d[1]=c*-e+g*b;d[2]=h*b+a*e;d[3]=h*-e+a*b;return d},multiplyVec2:function(a,b,d){d||(d=b);var c=b[0];b=b[1];d[0]=c*a[0]+b*a[1];d[1]=c*a[2]+b*a[3];return d},scale:function(a,b,d){d||(d=a);
var c=a[1],g=a[2],h=a[3],e=b[0];b=b[1];d[0]=a[0]*e;d[1]=c*b;d[2]=g*e;d[3]=h*b;return d},str:function(a){return"["+a[0]+", "+a[1]+", "+a[2]+", "+a[3]+"]"}},y={create:function(a){var c=new e(4);a?(c[0]=a[0],c[1]=a[1],c[2]=a[2],c[3]=a[3]):(c[0]=0,c[1]=0,c[2]=0,c[3]=0);return c},createFrom:function(a,b,d,g){var c=new e(4);c[0]=a;c[1]=b;c[2]=d;c[3]=g;return c},add:function(a,b,d){d||(d=b);d[0]=a[0]+b[0];d[1]=a[1]+b[1];d[2]=a[2]+b[2];d[3]=a[3]+b[3];return d},subtract:function(a,b,d){d||(d=b);d[0]=a[0]-
b[0];d[1]=a[1]-b[1];d[2]=a[2]-b[2];d[3]=a[3]-b[3];return d},multiply:function(a,b,d){d||(d=b);d[0]=a[0]*b[0];d[1]=a[1]*b[1];d[2]=a[2]*b[2];d[3]=a[3]*b[3];return d},divide:function(a,b,d){d||(d=b);d[0]=a[0]/b[0];d[1]=a[1]/b[1];d[2]=a[2]/b[2];d[3]=a[3]/b[3];return d},scale:function(a,b,d){d||(d=a);d[0]=a[0]*b;d[1]=a[1]*b;d[2]=a[2]*b;d[3]=a[3]*b;return d},set:function(a,b){b[0]=a[0];b[1]=a[1];b[2]=a[2];b[3]=a[3];return b},equal:function(a,b){return a===b||1E-6>Math.abs(a[0]-b[0])&&1E-6>Math.abs(a[1]-
b[1])&&1E-6>Math.abs(a[2]-b[2])&&1E-6>Math.abs(a[3]-b[3])},negate:function(a,b){b||(b=a);b[0]=-a[0];b[1]=-a[1];b[2]=-a[2];b[3]=-a[3];return b},length:function(a){var c=a[0],b=a[1],d=a[2];a=a[3];return Math.sqrt(c*c+b*b+d*d+a*a)},squaredLength:function(a){var c=a[0],b=a[1],d=a[2];a=a[3];return c*c+b*b+d*d+a*a},lerp:function(a,b,d,g){g||(g=a);g[0]=a[0]+d*(b[0]-a[0]);g[1]=a[1]+d*(b[1]-a[1]);g[2]=a[2]+d*(b[2]-a[2]);g[3]=a[3]+d*(b[3]-a[3]);return g},str:function(a){return"["+a[0]+", "+a[1]+", "+a[2]+", "+
a[3]+"]"}};f&&(f.glMatrixArrayType=e,f.MatrixArray=e,f.setMatrixArrayType=q,f.determineMatrixArrayType=n,f.glMath=r,f.vec2=w,f.vec3=k,f.vec4=y,f.mat2=z,f.mat3=v,f.mat4=m,f.quat4=x);return{glMatrixArrayType:e,MatrixArray:e,setMatrixArrayType:q,determineMatrixArrayType:n,glMath:r,vec2:w,vec3:k,vec4:y,mat2:z,mat3:v,mat4:m,quat4:x}});
(function(f){function q(a){return 0==a?0:0<a?1:-1}var n={subtract:function(a,b){return{x:a.x-b.x,y:a.y-b.y}},dotProduct:function(a,b){return a.x*b.x+a.y*b.y},square:function(a){return Math.sqrt(a.x*a.x+a.y*a.y)},scale:function(a,b){return{x:a.x*b,y:a.y*b}}},r=Math.pow(2,-65),e=function(a,d){for(var g=[],h=d.length-1,e=2*h-1,m=[],c=[],l=[],v=[],f=[[1,.6,.3,.1],[.4,.6,.6,.4],[.1,.3,.6,1]],x=0;x<=h;x++)m[x]=n.subtract(d[x],a);for(x=0;x<=h-1;x++)c[x]=n.subtract(d[x+1],d[x]),c[x]=n.scale(c[x],3);for(x=
0;x<=h-1;x++)for(var r=0;r<=h;r++)l[x]||(l[x]=[]),l[x][r]=n.dotProduct(c[x],m[r]);for(x=0;x<=e;x++)v[x]||(v[x]=[]),v[x].y=0,v[x].x=parseFloat(x)/e;e=h-1;for(m=0;m<=h+e;m++)for(c=Math.min(m,h),x=Math.max(0,m-e);x<=c;x++)r=m-x,v[x+r].y+=l[r][x]*f[r][x];h=d.length-1;v=k(v,2*h-1,g,0);e=n.subtract(a,d[0]);l=n.square(e);for(x=f=0;x<v;x++)e=n.subtract(a,b(d,h,g[x],null,null)),e=n.square(e),e<l&&(l=e,f=g[x]);e=n.subtract(a,d[h]);e=n.square(e);e<l&&(l=e,f=1);return{location:f,distance:l}},k=function(a,d,g,
h){var e=[],l=[],c=[],m=[],v=0;var f=q(a[0].y);for(var x=1;x<=d;x++){var u=q(a[x].y);u!=f&&v++;f=u}switch(v){case 0:return 0;case 1:if(64<=h)return g[0]=(a[0].x+a[d].x)/2,1;var w,n;v=a[0].y-a[d].y;u=a[d].x-a[0].x;f=a[0].x*a[d].y-a[d].x*a[0].y;x=w=0;for(n=1;n<d;n++){var G=v*a[n].x+u*a[n].y+f;G>w?w=G:G<x&&(x=G)}n=u;w=1/(0*n-1*v)*(f-w-0*n);n=u;v=1/(0*n-1*v)*(f-x-0*n);if(Math.max(w,v)-Math.min(w,v)<r)return c=a[d].x-a[0].x,m=a[d].y-a[0].y,g[0]=1/(0*c-1*m)*(c*(a[0].y-0)-m*(a[0].x-0)),1}b(a,d,.5,e,l);a=
k(e,d,c,h+1);d=k(l,d,m,h+1);for(h=0;h<a;h++)g[h]=c[h];for(h=0;h<d;h++)g[h+a]=m[h];return a+d},b=function(a,b,d,g,h){for(var e=[[]],c=0;c<=b;c++)e[0][c]=a[c];for(a=1;a<=b;a++)for(c=0;c<=b-a;c++)e[a]||(e[a]=[]),e[a][c]||(e[a][c]={}),e[a][c].x=(1-d)*e[a-1][c].x+d*e[a-1][c+1].x,e[a][c].y=(1-d)*e[a-1][c].y+d*e[a-1][c+1].y;if(null!=g)for(c=0;c<=b;c++)g[c]=e[c][0];if(null!=h)for(c=0;c<=b;c++)h[c]=e[b-c][c];return e[b][0]},d={},h=function(a){var b=d[a];if(!b){b=[];var g=function(a){return function(c){return a}},
h=function(){return function(a){return a}},e=function(){return function(a){return 1-a}},l=function(a){return function(c){for(var b=1,d=0;d<a.length;d++)b*=a[d](c);return b}};b.push(new function(){return function(c){return Math.pow(c,a)}});for(var c=1;c<a;c++){for(var m=[new g(a)],v=0;v<a-c;v++)m.push(new h);for(v=0;v<c;v++)m.push(new e);b.push(new l(m))}b.push(new function(){return function(c){return Math.pow(1-c,a)}});d[a]=b}return b},a=function(a,b){for(var d=h(a.length-1),g=0,e=0,l=0;l<a.length;l++)g+=
a[l].x*d[l](b),e+=a[l].y*d[l](b);return{x:g,y:e}},g=function(a,b){return Math.sqrt(Math.pow(a.x-b.x,2)+Math.pow(a.y-b.y,2))},l=function(b,d,h){for(var e=a(b,d),l=0,m=0<h?1:-1,c=null;l<Math.abs(h);)d+=.005*m,c=a(b,d),l+=g(c,e),e=c;return{point:c,location:d}},v=function(b,d){var g=a(b,d);d=a(b.slice(0,b.length-1),d);b=d.y-g.y;g=d.x-g.x;return 0==b?Infinity:Math.atan(b/g)};ChemDoodle.lib.jsBezier={distanceFromCurve:e,gradientAtPoint:v,gradientAtPointAlongCurveFrom:function(a,b,d){b=l(a,b,d);1<b.location&&
(b.location=1);0>b.location&&(b.location=0);return v(a,b.location)},nearestPointOnCurve:function(a,d){a=e(a,d);return{point:b(d,d.length-1,a.location,null,null),location:a.location}},pointOnCurve:a,pointAlongCurveFrom:function(a,b,d){return l(a,b,d).point},perpendicularToCurveAt:function(a,b,d,g){b=l(a,b,null==g?0:g);a=v(a,b.location);g=Math.atan(-1/a);a=d/2*Math.sin(g);d=d/2*Math.cos(g);return[{x:b.point.x+d,y:b.point.y+a},{x:b.point.x-d,y:b.point.y-a}]},locationAlongCurveFrom:function(a,b,d){return l(a,
b,d).location},getLength:function(b){for(var d=a(b,0),h=0,e=0,l;1>e;)e+=.005,l=a(b,e),h+=g(l,d),d=l;return h}}})(ChemDoodle.lib);
ChemDoodle.lib.MarchingCubes=function(){var f=new Uint32Array([0,265,515,778,1030,1295,1541,1804,2060,2309,2575,2822,3082,3331,3593,3840,400,153,915,666,1430,1183,1941,1692,2460,2197,2975,2710,3482,3219,3993,3728,560,825,51,314,1590,1855,1077,1340,2620,2869,2111,2358,3642,3891,3129,3376,928,681,419,170,1958,1711,1445,1196,2988,2725,2479,2214,4010,3747,3497,3232,1120,1385,1635,1898,102,367,613,876,3180,3429,3695,3942,2154,2403,2665,2912,1520,1273,2035,1786,502,255,1013,764,3580,3317,4095,3830,2554,
2291,3065,2800,1616,1881,1107,1370,598,863,85,348,3676,3925,3167,3414,2650,2899,2137,2384,1984,1737,1475,1226,966,719,453,204,4044,3781,3535,3270,3018,2755,2505,2240,2240,2505,2755,3018,3270,3535,3781,4044,204,453,719,966,1226,1475,1737,1984,2384,2137,2899,2650,3414,3167,3925,3676,348,85,863,598,1370,1107,1881,1616,2800,3065,2291,2554,3830,4095,3317,3580,764,1013,255,502,1786,2035,1273,1520,2912,2665,2403,2154,3942,3695,3429,3180,876,613,367,102,1898,1635,1385,1120,3232,3497,3747,4010,2214,2479,2725,
2988,1196,1445,1711,1958,170,419,681,928,3376,3129,3891,3642,2358,2111,2869,2620,1340,1077,1855,1590,314,51,825,560,3728,3993,3219,3482,2710,2975,2197,2460,1692,1941,1183,1430,666,915,153,400,3840,3593,3331,3082,2822,2575,2309,2060,1804,1541,1295,1030,778,515,265,0]),q=[[],[0,8,3],[0,1,9],[1,8,3,9,8,1],[1,2,10],[0,8,3,1,2,10],[9,2,10,0,2,9],[2,8,3,2,10,8,10,9,8],[3,11,2],[0,11,2,8,11,0],[1,9,0,2,3,11],[1,11,2,1,9,11,9,8,11],[3,10,1,11,10,3],[0,10,1,0,8,10,8,11,10],[3,9,0,3,11,9,11,10,9],[9,8,10,10,
8,11],[4,7,8],[4,3,0,7,3,4],[0,1,9,8,4,7],[4,1,9,4,7,1,7,3,1],[1,2,10,8,4,7],[3,4,7,3,0,4,1,2,10],[9,2,10,9,0,2,8,4,7],[2,10,9,2,9,7,2,7,3,7,9,4],[8,4,7,3,11,2],[11,4,7,11,2,4,2,0,4],[9,0,1,8,4,7,2,3,11],[4,7,11,9,4,11,9,11,2,9,2,1],[3,10,1,3,11,10,7,8,4],[1,11,10,1,4,11,1,0,4,7,11,4],[4,7,8,9,0,11,9,11,10,11,0,3],[4,7,11,4,11,9,9,11,10],[9,5,4],[9,5,4,0,8,3],[0,5,4,1,5,0],[8,5,4,8,3,5,3,1,5],[1,2,10,9,5,4],[3,0,8,1,2,10,4,9,5],[5,2,10,5,4,2,4,0,2],[2,10,5,3,2,5,3,5,4,3,4,8],[9,5,4,2,3,11],[0,11,
2,0,8,11,4,9,5],[0,5,4,0,1,5,2,3,11],[2,1,5,2,5,8,2,8,11,4,8,5],[10,3,11,10,1,3,9,5,4],[4,9,5,0,8,1,8,10,1,8,11,10],[5,4,0,5,0,11,5,11,10,11,0,3],[5,4,8,5,8,10,10,8,11],[9,7,8,5,7,9],[9,3,0,9,5,3,5,7,3],[0,7,8,0,1,7,1,5,7],[1,5,3,3,5,7],[9,7,8,9,5,7,10,1,2],[10,1,2,9,5,0,5,3,0,5,7,3],[8,0,2,8,2,5,8,5,7,10,5,2],[2,10,5,2,5,3,3,5,7],[7,9,5,7,8,9,3,11,2],[9,5,7,9,7,2,9,2,0,2,7,11],[2,3,11,0,1,8,1,7,8,1,5,7],[11,2,1,11,1,7,7,1,5],[9,5,8,8,5,7,10,1,3,10,3,11],[5,7,0,5,0,9,7,11,0,1,0,10,11,10,0],[11,10,
0,11,0,3,10,5,0,8,0,7,5,7,0],[11,10,5,7,11,5],[10,6,5],[0,8,3,5,10,6],[9,0,1,5,10,6],[1,8,3,1,9,8,5,10,6],[1,6,5,2,6,1],[1,6,5,1,2,6,3,0,8],[9,6,5,9,0,6,0,2,6],[5,9,8,5,8,2,5,2,6,3,2,8],[2,3,11,10,6,5],[11,0,8,11,2,0,10,6,5],[0,1,9,2,3,11,5,10,6],[5,10,6,1,9,2,9,11,2,9,8,11],[6,3,11,6,5,3,5,1,3],[0,8,11,0,11,5,0,5,1,5,11,6],[3,11,6,0,3,6,0,6,5,0,5,9],[6,5,9,6,9,11,11,9,8],[5,10,6,4,7,8],[4,3,0,4,7,3,6,5,10],[1,9,0,5,10,6,8,4,7],[10,6,5,1,9,7,1,7,3,7,9,4],[6,1,2,6,5,1,4,7,8],[1,2,5,5,2,6,3,0,4,3,4,
7],[8,4,7,9,0,5,0,6,5,0,2,6],[7,3,9,7,9,4,3,2,9,5,9,6,2,6,9],[3,11,2,7,8,4,10,6,5],[5,10,6,4,7,2,4,2,0,2,7,11],[0,1,9,4,7,8,2,3,11,5,10,6],[9,2,1,9,11,2,9,4,11,7,11,4,5,10,6],[8,4,7,3,11,5,3,5,1,5,11,6],[5,1,11,5,11,6,1,0,11,7,11,4,0,4,11],[0,5,9,0,6,5,0,3,6,11,6,3,8,4,7],[6,5,9,6,9,11,4,7,9,7,11,9],[10,4,9,6,4,10],[4,10,6,4,9,10,0,8,3],[10,0,1,10,6,0,6,4,0],[8,3,1,8,1,6,8,6,4,6,1,10],[1,4,9,1,2,4,2,6,4],[3,0,8,1,2,9,2,4,9,2,6,4],[0,2,4,4,2,6],[8,3,2,8,2,4,4,2,6],[10,4,9,10,6,4,11,2,3],[0,8,2,2,8,
11,4,9,10,4,10,6],[3,11,2,0,1,6,0,6,4,6,1,10],[6,4,1,6,1,10,4,8,1,2,1,11,8,11,1],[9,6,4,9,3,6,9,1,3,11,6,3],[8,11,1,8,1,0,11,6,1,9,1,4,6,4,1],[3,11,6,3,6,0,0,6,4],[6,4,8,11,6,8],[7,10,6,7,8,10,8,9,10],[0,7,3,0,10,7,0,9,10,6,7,10],[10,6,7,1,10,7,1,7,8,1,8,0],[10,6,7,10,7,1,1,7,3],[1,2,6,1,6,8,1,8,9,8,6,7],[2,6,9,2,9,1,6,7,9,0,9,3,7,3,9],[7,8,0,7,0,6,6,0,2],[7,3,2,6,7,2],[2,3,11,10,6,8,10,8,9,8,6,7],[2,0,7,2,7,11,0,9,7,6,7,10,9,10,7],[1,8,0,1,7,8,1,10,7,6,7,10,2,3,11],[11,2,1,11,1,7,10,6,1,6,7,1],[8,
9,6,8,6,7,9,1,6,11,6,3,1,3,6],[0,9,1,11,6,7],[7,8,0,7,0,6,3,11,0,11,6,0],[7,11,6],[7,6,11],[3,0,8,11,7,6],[0,1,9,11,7,6],[8,1,9,8,3,1,11,7,6],[10,1,2,6,11,7],[1,2,10,3,0,8,6,11,7],[2,9,0,2,10,9,6,11,7],[6,11,7,2,10,3,10,8,3,10,9,8],[7,2,3,6,2,7],[7,0,8,7,6,0,6,2,0],[2,7,6,2,3,7,0,1,9],[1,6,2,1,8,6,1,9,8,8,7,6],[10,7,6,10,1,7,1,3,7],[10,7,6,1,7,10,1,8,7,1,0,8],[0,3,7,0,7,10,0,10,9,6,10,7],[7,6,10,7,10,8,8,10,9],[6,8,4,11,8,6],[3,6,11,3,0,6,0,4,6],[8,6,11,8,4,6,9,0,1],[9,4,6,9,6,3,9,3,1,11,3,6],[6,
8,4,6,11,8,2,10,1],[1,2,10,3,0,11,0,6,11,0,4,6],[4,11,8,4,6,11,0,2,9,2,10,9],[10,9,3,10,3,2,9,4,3,11,3,6,4,6,3],[8,2,3,8,4,2,4,6,2],[0,4,2,4,6,2],[1,9,0,2,3,4,2,4,6,4,3,8],[1,9,4,1,4,2,2,4,6],[8,1,3,8,6,1,8,4,6,6,10,1],[10,1,0,10,0,6,6,0,4],[4,6,3,4,3,8,6,10,3,0,3,9,10,9,3],[10,9,4,6,10,4],[4,9,5,7,6,11],[0,8,3,4,9,5,11,7,6],[5,0,1,5,4,0,7,6,11],[11,7,6,8,3,4,3,5,4,3,1,5],[9,5,4,10,1,2,7,6,11],[6,11,7,1,2,10,0,8,3,4,9,5],[7,6,11,5,4,10,4,2,10,4,0,2],[3,4,8,3,5,4,3,2,5,10,5,2,11,7,6],[7,2,3,7,6,2,
5,4,9],[9,5,4,0,8,6,0,6,2,6,8,7],[3,6,2,3,7,6,1,5,0,5,4,0],[6,2,8,6,8,7,2,1,8,4,8,5,1,5,8],[9,5,4,10,1,6,1,7,6,1,3,7],[1,6,10,1,7,6,1,0,7,8,7,0,9,5,4],[4,0,10,4,10,5,0,3,10,6,10,7,3,7,10],[7,6,10,7,10,8,5,4,10,4,8,10],[6,9,5,6,11,9,11,8,9],[3,6,11,0,6,3,0,5,6,0,9,5],[0,11,8,0,5,11,0,1,5,5,6,11],[6,11,3,6,3,5,5,3,1],[1,2,10,9,5,11,9,11,8,11,5,6],[0,11,3,0,6,11,0,9,6,5,6,9,1,2,10],[11,8,5,11,5,6,8,0,5,10,5,2,0,2,5],[6,11,3,6,3,5,2,10,3,10,5,3],[5,8,9,5,2,8,5,6,2,3,8,2],[9,5,6,9,6,0,0,6,2],[1,5,8,1,
8,0,5,6,8,3,8,2,6,2,8],[1,5,6,2,1,6],[1,3,6,1,6,10,3,8,6,5,6,9,8,9,6],[10,1,0,10,0,6,9,5,0,5,6,0],[0,3,8,5,6,10],[10,5,6],[11,5,10,7,5,11],[11,5,10,11,7,5,8,3,0],[5,11,7,5,10,11,1,9,0],[10,7,5,10,11,7,9,8,1,8,3,1],[11,1,2,11,7,1,7,5,1],[0,8,3,1,2,7,1,7,5,7,2,11],[9,7,5,9,2,7,9,0,2,2,11,7],[7,5,2,7,2,11,5,9,2,3,2,8,9,8,2],[2,5,10,2,3,5,3,7,5],[8,2,0,8,5,2,8,7,5,10,2,5],[9,0,1,5,10,3,5,3,7,3,10,2],[9,8,2,9,2,1,8,7,2,10,2,5,7,5,2],[1,3,5,3,7,5],[0,8,7,0,7,1,1,7,5],[9,0,3,9,3,5,5,3,7],[9,8,7,5,9,7],[5,
8,4,5,10,8,10,11,8],[5,0,4,5,11,0,5,10,11,11,3,0],[0,1,9,8,4,10,8,10,11,10,4,5],[10,11,4,10,4,5,11,3,4,9,4,1,3,1,4],[2,5,1,2,8,5,2,11,8,4,5,8],[0,4,11,0,11,3,4,5,11,2,11,1,5,1,11],[0,2,5,0,5,9,2,11,5,4,5,8,11,8,5],[9,4,5,2,11,3],[2,5,10,3,5,2,3,4,5,3,8,4],[5,10,2,5,2,4,4,2,0],[3,10,2,3,5,10,3,8,5,4,5,8,0,1,9],[5,10,2,5,2,4,1,9,2,9,4,2],[8,4,5,8,5,3,3,5,1],[0,4,5,1,0,5],[8,4,5,8,5,3,9,0,5,0,3,5],[9,4,5],[4,11,7,4,9,11,9,10,11],[0,8,3,4,9,7,9,11,7,9,10,11],[1,10,11,1,11,4,1,4,0,7,4,11],[3,1,4,3,4,8,
1,10,4,7,4,11,10,11,4],[4,11,7,9,11,4,9,2,11,9,1,2],[9,7,4,9,11,7,9,1,11,2,11,1,0,8,3],[11,7,4,11,4,2,2,4,0],[11,7,4,11,4,2,8,3,4,3,2,4],[2,9,10,2,7,9,2,3,7,7,4,9],[9,10,7,9,7,4,10,2,7,8,7,0,2,0,7],[3,7,10,3,10,2,7,4,10,1,10,0,4,0,10],[1,10,2,8,7,4],[4,9,1,4,1,7,7,1,3],[4,9,1,4,1,7,0,8,1,8,7,1],[4,0,3,7,4,3],[4,8,7],[9,10,8,10,11,8],[3,0,9,3,9,11,11,9,10],[0,1,10,0,10,8,8,10,11],[3,1,10,11,3,10],[1,2,11,1,11,9,9,11,8],[3,0,9,3,9,11,1,2,9,2,11,9],[0,2,11,8,0,11],[3,2,11],[2,3,8,2,8,10,10,8,9],[9,10,
2,0,9,2],[2,3,8,2,8,10,0,1,8,1,10,8],[1,10,2],[1,3,8,9,1,8],[0,9,1],[0,3,8],[]],n=[[0,0,0],[1,0,0],[1,1,0],[0,1,0],[0,0,1],[1,0,1],[1,1,1],[0,1,1]],r=[[0,1],[1,2],[2,3],[3,0],[4,5],[5,6],[6,7],[7,4],[0,4],[1,5],[2,6],[3,7]];return function(e,k){var b=[],d=[],h=0,a=new Float32Array(8),g=new Int32Array(12),l=new Int32Array(3);for(l[2]=0;l[2]<k[2]-1;++l[2],h+=k[0])for(l[1]=0;l[1]<k[1]-1;++l[1],++h)for(l[0]=0;l[0]<k[0]-1;++l[0],++h){for(var v=0,m=0;8>m;++m){var x=n[m];x=e[h+x[0]+k[0]*(x[1]+k[1]*x[2])];
a[m]=x;v|=0<x?1<<m:0}x=f[v];if(0!==x){for(m=0;12>m;++m)if(0!==(x&1<<m)){g[m]=b.length;var u=[0,0,0],w=r[m],z=n[w[0]],y=n[w[1]],c=a[w[0]],p=c-a[w[1]];w=0;1E-6<Math.abs(p)&&(w=c/p);for(c=0;3>c;++c)u[c]=l[c]+z[c]+w*(y[c]-z[c]);b.push(u)}v=q[v];for(m=0;m<v.length;m+=3)d.push([g[v[m]],g[v[m+1]],g[v[m+2]]])}}return{vertices:b,faces:d}}}();
ChemDoodle.animations=function(f,q){q={};f.requestAnimFrame=function(){return f.requestAnimationFrame||f.webkitRequestAnimationFrame||f.mozRequestAnimationFrame||f.oRequestAnimationFrame||f.msRequestAnimationFrame||function(n,r){f.setTimeout(n,1E3/60)}}();q.requestInterval=function(n,r){function e(){(new Date).getTime()-k>=r&&(n.call(),k=(new Date).getTime());b.value=f.requestAnimFrame(e)}if(!(f.requestAnimationFrame||f.webkitRequestAnimationFrame||f.mozRequestAnimationFrame&&f.mozCancelRequestAnimationFrame||
f.oRequestAnimationFrame||f.msRequestAnimationFrame))return f.setInterval(n,r);let k=(new Date).getTime(),b={};b.value=f.requestAnimFrame(e);return b};q.clearRequestInterval=function(n){f.cancelAnimationFrame?f.cancelAnimationFrame(n.value):f.webkitCancelAnimationFrame?f.webkitCancelAnimationFrame(n.value):f.webkitCancelRequestAnimationFrame?f.webkitCancelRequestAnimationFrame(n.value):f.mozCancelRequestAnimationFrame?f.mozCancelRequestAnimationFrame(n.value):f.oCancelRequestAnimationFrame?f.oCancelRequestAnimationFrame(n.value):
f.msCancelRequestAnimationFrame?f.msCancelRequestAnimationFrame(n.value):clearInterval(n)};q.requestTimeout=function(n,r){function e(){(new Date).getTime()-k>=r?n.call():b.value=f.requestAnimFrame(e)}if(!(f.requestAnimationFrame||f.webkitRequestAnimationFrame||f.mozRequestAnimationFrame&&f.mozCancelRequestAnimationFrame||f.oRequestAnimationFrame||f.msRequestAnimationFrame))return f.setTimeout(n,r);let k=(new Date).getTime(),b={};b.value=f.requestAnimFrame(e);return b};q.clearRequestTimeout=function(n){f.cancelAnimationFrame?
f.cancelAnimationFrame(n.value):f.webkitCancelAnimationFrame?f.webkitCancelAnimationFrame(n.value):f.webkitCancelRequestAnimationFrame?f.webkitCancelRequestAnimationFrame(n.value):f.mozCancelRequestAnimationFrame?f.mozCancelRequestAnimationFrame(n.value):f.oCancelRequestAnimationFrame?f.oCancelRequestAnimationFrame(n.value):f.msCancelRequestAnimationFrame?f.msCancelRequestAnimationFrame(n.value):clearTimeout(n)};return q}(window);
ChemDoodle.extensions=function(f,q,n,r){return{vec3AngleFrom:function(e,f){let b=q.length(e),d=q.length(f);e=q.dot(e,f);return n.acos(e/b/d)},contextRoundRect:function(e,f,b,d,h,a){e.beginPath();e.moveTo(f+a,b);e.lineTo(f+d-a,b);e.quadraticCurveTo(f+d,b,f+d,b+a);e.lineTo(f+d,b+h-a);e.quadraticCurveTo(f+d,b+h,f+d-a,b+h);e.lineTo(f+a,b+h);e.quadraticCurveTo(f,b+h,f,b+h-a);e.lineTo(f,b+a);e.quadraticCurveTo(f,b,f+a,b);e.closePath()},contextEllipse:function(e,f,b,d,h){let a=d/2*.5522848,g=h/2*.5522848,
l=f+d,v=b+h;d=f+d/2;h=b+h/2;e.beginPath();e.moveTo(f,h);e.bezierCurveTo(f,h-g,d-a,b,d,b);e.bezierCurveTo(d+a,b,l,h-g,l,h);e.bezierCurveTo(l,h+g,d+a,v,d,v);e.bezierCurveTo(d-a,v,f,h+g,f,h);e.closePath()},getFontString:function(e,f,b,d){let h=[];b&&h.push("bold ");d&&h.push("italic ");h.push(e+"px ");for(let a=0,b=f.length;a<b;a++)e=f[a],-1!==e.indexOf(" ")&&(e='"'+e+'"'),h.push((0!==a?",":"")+e);return h.join("")}}}(ChemDoodle.structures,ChemDoodle.lib.vec3,Math);
(function(f,q,n){q.sign||(q.sign=function(f){return(0<f)-(0>f)||+f});"function"!=typeof f.assign&&(f.assign=function(r,e){if(null==r)throw new TypeError("Cannot convert undefined or null to object");for(var k=f(r),b=1;b<arguments.length;b++){var d=arguments[b];if(null!=d)for(var h in d)f.prototype.hasOwnProperty.call(d,h)&&(k[h]=d[h])}return k});String.prototype.startsWith||(String.prototype.startsWith=function(f,e){return this.substr(e||0,f.length)===f})})(Object,Math);
ChemDoodle.math=function(f,q,n,r,e){let k={},b={aliceblue:"#f0f8ff",antiquewhite:"#faebd7",aqua:"#00ffff",aquamarine:"#7fffd4",azure:"#f0ffff",beige:"#f5f5dc",bisque:"#ffe4c4",black:"#000000",blanchedalmond:"#ffebcd",blue:"#0000ff",blueviolet:"#8a2be2",brown:"#a52a2a",burlywood:"#deb887",cadetblue:"#5f9ea0",chartreuse:"#7fff00",chocolate:"#d2691e",coral:"#ff7f50",cornflowerblue:"#6495ed",cornsilk:"#fff8dc",crimson:"#dc143c",cyan:"#00ffff",darkblue:"#00008b",darkcyan:"#008b8b",darkgoldenrod:"#b8860b",
darkgray:"#a9a9a9",darkgreen:"#006400",darkkhaki:"#bdb76b",darkmagenta:"#8b008b",darkolivegreen:"#556b2f",darkorange:"#ff8c00",darkorchid:"#9932cc",darkred:"#8b0000",darksalmon:"#e9967a",darkseagreen:"#8fbc8f",darkslateblue:"#483d8b",darkslategray:"#2f4f4f",darkturquoise:"#00ced1",darkviolet:"#9400d3",deeppink:"#ff1493",deepskyblue:"#00bfff",dimgray:"#696969",dodgerblue:"#1e90ff",firebrick:"#b22222",floralwhite:"#fffaf0",forestgreen:"#228b22",fuchsia:"#ff00ff",gainsboro:"#dcdcdc",ghostwhite:"#f8f8ff",
gold:"#ffd700",goldenrod:"#daa520",gray:"#808080",green:"#008000",greenyellow:"#adff2f",honeydew:"#f0fff0",hotpink:"#ff69b4","indianred ":"#cd5c5c","indigo ":"#4b0082",ivory:"#fffff0",khaki:"#f0e68c",lavender:"#e6e6fa",lavenderblush:"#fff0f5",lawngreen:"#7cfc00",lemonchiffon:"#fffacd",lightblue:"#add8e6",lightcoral:"#f08080",lightcyan:"#e0ffff",lightgoldenrodyellow:"#fafad2",lightgrey:"#d3d3d3",lightgreen:"#90ee90",lightpink:"#ffb6c1",lightsalmon:"#ffa07a",lightseagreen:"#20b2aa",lightskyblue:"#87cefa",
lightslategray:"#778899",lightsteelblue:"#b0c4de",lightyellow:"#ffffe0",lime:"#00ff00",limegreen:"#32cd32",linen:"#faf0e6",magenta:"#ff00ff",maroon:"#800000",mediumaquamarine:"#66cdaa",mediumblue:"#0000cd",mediumorchid:"#ba55d3",mediumpurple:"#9370d8",mediumseagreen:"#3cb371",mediumslateblue:"#7b68ee",mediumspringgreen:"#00fa9a",mediumturquoise:"#48d1cc",mediumvioletred:"#c71585",midnightblue:"#191970",mintcream:"#f5fffa",mistyrose:"#ffe4e1",moccasin:"#ffe4b5",navajowhite:"#ffdead",navy:"#000080",
oldlace:"#fdf5e6",olive:"#808000",olivedrab:"#6b8e23",orange:"#ffa500",orangered:"#ff4500",orchid:"#da70d6",palegoldenrod:"#eee8aa",palegreen:"#98fb98",paleturquoise:"#afeeee",palevioletred:"#d87093",papayawhip:"#ffefd5",peachpuff:"#ffdab9",peru:"#cd853f",pink:"#ffc0cb",plum:"#dda0dd",powderblue:"#b0e0e6",purple:"#800080",red:"#ff0000",rosybrown:"#bc8f8f",royalblue:"#4169e1",saddlebrown:"#8b4513",salmon:"#fa8072",sandybrown:"#f4a460",seagreen:"#2e8b57",seashell:"#fff5ee",sienna:"#a0522d",silver:"#c0c0c0",
skyblue:"#87ceeb",slateblue:"#6a5acd",slategray:"#708090",snow:"#fffafa",springgreen:"#00ff7f",steelblue:"#4682b4",tan:"#d2b48c",teal:"#008080",thistle:"#d8bfd8",tomato:"#ff6347",turquoise:"#40e0d0",violet:"#ee82ee",wheat:"#f5deb3",white:"#ffffff",whitesmoke:"#f5f5f5",yellow:"#ffff00",yellowgreen:"#9acd32"};k.angleBetweenLargest=function(b){if(0===b.length)return{angle:0,largest:2*r.PI};if(1===b.length)return{angle:b[0]+r.PI,largest:2*r.PI};let d=0,a=0;for(let h=0,e=b.length-1;h<e;h++){var g=b[h+
1]-b[h];g>d&&(d=g,a=(b[h+1]+b[h])/2)}g=b[0]+2*r.PI-b[b.length-1];g>d&&(a=b[0]-g/2,d=g,0>a&&(a+=2*r.PI));return{angle:a,largest:d}};k.isBetween=function(b,h,a){if(h>a){let b=h;h=a;a=b}return b>=h&&b<=a};n(document).ready(function(){f&&f.iChemLabs&&f.iChemLabs.checkForUpdates&&f.iChemLabs.checkForUpdates({})});k.getRGB=function(d,h){let a=[0,0,0];b[d.toLowerCase()]&&(d=b[d.toLowerCase()]);return"#"===d.charAt(0)?(4===d.length&&(d="#"+d.charAt(1)+d.charAt(1)+d.charAt(2)+d.charAt(2)+d.charAt(3)+d.charAt(3)),
[parseInt(d.substring(1,3),16)/255*h,parseInt(d.substring(3,5),16)/255*h,parseInt(d.substring(5,7),16)/255*h]):d.startsWith("rgba")?(d=d.replace(/rgba\(|\)/g,"").split(","),4!==d.length?a:[parseInt(d[0])/255*h,parseInt(d[1])/255*h,parseInt(d[2])/255*h,parseInt(d[3])/255*h]):d.startsWith("rgb")?(d=d.replace(/rgb\(|\)/g,"").split(","),3!==d.length?a:[parseInt(d[0])/255*h,parseInt(d[1])/255*h,parseInt(d[2])/255*h]):a};k.hsl2rgb=function(b,h,a){let d=function(a,b,d){0>d?d+=1:1<d&&--d;return d<1/6?a+6*
(b-a)*d:.5>d?b:d<2/3?a+(b-a)*(2/3-d)*6:a};if(0===h)a=h=b=a;else{let g=.5>a?a*(1+h):a+h-a*h,e=2*a-g;a=d(e,g,b+1/3);h=d(e,g,b);b=d(e,g,b-1/3)}return[255*a,255*h,255*b]};k.idx2color=function(b){b=b.toString(16);for(let d=0,a=6-b.length;d<a;d++)b="0"+b;return"#"+b};k.distanceFromPointToLineInclusive=function(b,h,a,g){let d=h.distance(a);a=h.angle(a);a=r.PI/2-a;a=h.angle(b)+a;b=h.distance(b);b=new q.Point(b*r.cos(a),-b*r.sin(a));g=g?g:0;return k.isBetween(-b.y,g,d-g)?r.abs(b.x):-1};k.calculateDistanceInterior=
function(b,h,a){if(this.isBetween(h.x,a.x,a.x+a.w)&&this.isBetween(h.y,a.y,a.y+a.h))return b.distance(h);var d=[];d.push({x1:a.x,y1:a.y,x2:a.x+a.w,y2:a.y});d.push({x1:a.x,y1:a.y+a.h,x2:a.x+a.w,y2:a.y+a.h});d.push({x1:a.x,y1:a.y,x2:a.x,y2:a.y+a.h});d.push({x1:a.x+a.w,y1:a.y,x2:a.x+a.w,y2:a.y+a.h});a=[];for(var e=0;4>e;e++){var f=d[e];(f=this.intersectLines(h.x,h.y,b.x,b.y,f.x1,f.y1,f.x2,f.y2))&&a.push(f)}if(0===a.length)return 0;h=0;for(let g=0,l=a.length;g<l;g++)e=a[g],d=b.x-e.x,e=b.y-e.y,h=r.max(h,
r.sqrt(d*d+e*e));return h};k.intersectLines=function(b,h,a,g,e,f,m,k){a-=b;g-=h;m-=e;k-=f;let d=g*m-a*k;if(0===d)return!1;m=(k*(b-e)-m*(h-f))/d;e=(g*(b-e)-a*(h-f))/d;return 0<=e&&1>=e&&0<=m&&1>=m?{x:b+m*a,y:h+m*g}:!1};k.clamp=function(b,h,a){return b<h?h:b>a?a:b};k.rainbowAt=function(b,h,a){1>a.length?a.push("#000000","#FFFFFF"):2>a.length&&a.push("#FFFFFF");var d=h/(a.length-1);h=r.floor(b/d);b=(b-h*d)/d;d=k.getRGB(a[h],1);a=k.getRGB(a[h+1],1);return"rgb("+[255*(d[0]+(a[0]-d[0])*b),255*(d[1]+(a[1]-
d[1])*b),255*(d[2]+(a[2]-d[2])*b)].join()+")"};k.angleBounds=function(b,h,a){let d=2*r.PI;for(;0>b;)b+=d;for(;b>d;)b-=d;a&&b>r.PI&&(b=2*r.PI-b);h&&(b=180*b/r.PI);return b};k.isPointInPoly=function(b,h){for(var a=!1,d=-1,e=b.length,f=e-1;++d<e;f=d)(b[d].y<=h.y&&h.y<b[f].y||b[f].y<=h.y&&h.y<b[d].y)&&h.x<(b[f].x-b[d].x)*(h.y-b[d].y)/(b[f].y-b[d].y)+b[d].x&&(a=!a);return a};return k}(ChemDoodle,ChemDoodle.structures,ChemDoodle.lib.jQuery,Math);
(function(f,q,n){f.Bounds=function(){};let r=f.Bounds.prototype;r.minX=r.minY=r.minZ=Infinity;r.maxX=r.maxY=r.maxZ=-Infinity;r.expand=function(e,k,b,d){e instanceof f.Bounds?(this.minX=q.min(this.minX,e.minX),this.minY=q.min(this.minY,e.minY),this.maxX=q.max(this.maxX,e.maxX),this.maxY=q.max(this.maxY,e.maxY),Infinity!==e.maxZ&&(this.minZ=q.min(this.minZ,e.minZ),this.maxZ=q.max(this.maxZ,e.maxZ))):(this.minX=q.min(this.minX,e),this.maxX=q.max(this.maxX,e),this.minY=q.min(this.minY,k),this.maxY=q.max(this.maxY,
k),b!==n&&d!==n&&(this.minX=q.min(this.minX,b),this.maxX=q.max(this.maxX,b),this.minY=q.min(this.minY,d),this.maxY=q.max(this.maxY,d)))};r.expand3D=function(e,f,b,d,h,a){this.minX=q.min(this.minX,e);this.maxX=q.max(this.maxX,e);this.minY=q.min(this.minY,f);this.maxY=q.max(this.maxY,f);this.minZ=q.min(this.minZ,b);this.maxZ=q.max(this.maxZ,b);d!==n&&h!==n&&a!==n&&(this.minX=q.min(this.minX,d),this.maxX=q.max(this.maxX,d),this.minY=q.min(this.minY,h),this.maxY=q.max(this.maxY,h),this.minZ=q.min(this.minZ,
a),this.maxZ=q.max(this.maxZ,a))}})(ChemDoodle.math,Math);
ChemDoodle.featureDetection=function(f,q,n,r,e){let k={supports_canvas:function(){return!!n.createElement("canvas").getContext},supports_canvas_text:function(){return k.supports_canvas()?"function"===typeof n.createElement("canvas").getContext("2d").fillText:!1},supports_webgl:function(){let b=n.createElement("canvas");try{if(b.getContext("webgl")||b.getContext("experimental-webgl"))return!0}catch(d){}return!1},supports_xhr2:function(){return q.support.cors},supports_touch:function(){let b=(/iPhone|iPad|iPod|Android|BlackBerry|BB10/i.test(navigator.userAgent)||
"MacIntel"===navigator.platform&&1<navigator.maxTouchPoints)&&!r.MSStream;return"ontouchstart"in r&&b},supports_gesture:function(){return"ongesturestart"in r}};return k}(ChemDoodle.iChemLabs,ChemDoodle.lib.jQuery,document,window);ChemDoodle.SYMBOLS="H He Li Be B C N O F Ne Na Mg Al Si P S Cl Ar K Ca Sc Ti V Cr Mn Fe Co Ni Cu Zn Ga Ge As Se Br Kr Rb Sr Y Zr Nb Mo Tc Ru Rh Pd Ag Cd In Sn Sb Te I Xe Cs Ba La Ce Pr Nd Pm Sm Eu Gd Tb Dy Ho Er Tm Yb Lu Hf Ta W Re Os Ir Pt Au Hg Tl Pb Bi Po At Rn Fr Ra Ac Th Pa U Np Pu Am Cm Bk Cf Es Fm Md No Lr Rf Db Sg Bh Hs Mt Ds Rg Cn Nh Fl Mc Lv Ts Og".split(" ");
ChemDoodle.ELEMENT=function(f,q){function n(f,e,k,b,d,h,a,g,l){this.symbol=f;this.name=e;this.atomicNumber=k;this.addH=b;this.jmolColor=this.pymolColor=d;this.covalentRadius=h;this.vdWRadius=a;this.valency=g;this.mass=l}f=[];f.H=new n("H","Hydrogen",1,!1,"#FFFFFF",.31,1.1,1,1);f.He=new n("He","Helium",2,!1,"#D9FFFF",.28,1.4,0,4);f.Li=new n("Li","Lithium",3,!1,"#CC80FF",1.28,1.82,1,7);f.Be=new n("Be","Beryllium",4,!1,"#C2FF00",.96,1.53,2,9);f.B=new n("B","Boron",5,!0,"#FFB5B5",.84,1.92,3,11);f.C=new n("C",
"Carbon",6,!0,"#909090",.76,1.7,4,12);f.N=new n("N","Nitrogen",7,!0,"#3050F8",.71,1.55,3,14);f.O=new n("O","Oxygen",8,!0,"#FF0D0D",.66,1.52,2,16);f.F=new n("F","Fluorine",9,!0,"#90E050",.57,1.47,1,19);f.Ne=new n("Ne","Neon",10,!1,"#B3E3F5",.58,1.54,0,20);f.Na=new n("Na","Sodium",11,!1,"#AB5CF2",1.66,2.27,1,23);f.Mg=new n("Mg","Magnesium",12,!1,"#8AFF00",1.41,1.73,0,24);f.Al=new n("Al","Aluminum",13,!1,"#BFA6A6",1.21,1.84,0,27);f.Si=new n("Si","Silicon",14,!0,"#F0C8A0",1.11,2.1,4,28);f.P=new n("P",
"Phosphorus",15,!0,"#FF8000",1.07,1.8,3,31);f.S=new n("S","Sulfur",16,!0,"#FFFF30",1.05,1.8,2,32);f.Cl=new n("Cl","Chlorine",17,!0,"#1FF01F",1.02,1.75,1,35);f.Ar=new n("Ar","Argon",18,!1,"#80D1E3",1.06,1.88,0,40);f.K=new n("K","Potassium",19,!1,"#8F40D4",2.03,2.75,0,39);f.Ca=new n("Ca","Calcium",20,!1,"#3DFF00",1.76,2.31,0,40);f.Sc=new n("Sc","Scandium",21,!1,"#E6E6E6",1.7,0,0,45);f.Ti=new n("Ti","Titanium",22,!1,"#BFC2C7",1.6,0,1,48);f.V=new n("V","Vanadium",23,!1,"#A6A6AB",1.53,0,1,51);f.Cr=new n("Cr",
"Chromium",24,!1,"#8A99C7",1.39,0,2,52);f.Mn=new n("Mn","Manganese",25,!1,"#9C7AC7",1.39,0,3,55);f.Fe=new n("Fe","Iron",26,!1,"#E06633",1.32,0,2,56);f.Co=new n("Co","Cobalt",27,!1,"#F090A0",1.26,0,1,59);f.Ni=new n("Ni","Nickel",28,!1,"#50D050",1.24,1.63,1,58);f.Cu=new n("Cu","Copper",29,!1,"#C88033",1.32,1.4,0,63);f.Zn=new n("Zn","Zinc",30,!1,"#7D80B0",1.22,1.39,0,64);f.Ga=new n("Ga","Gallium",31,!1,"#C28F8F",1.22,1.87,0,69);f.Ge=new n("Ge","Germanium",32,!1,"#668F8F",1.2,2.11,4,74);f.As=new n("As",
"Arsenic",33,!0,"#BD80E3",1.19,1.85,3,75);f.Se=new n("Se","Selenium",34,!0,"#FFA100",1.2,1.9,2,80);f.Br=new n("Br","Bromine",35,!0,"#A62929",1.2,1.85,1,79);f.Kr=new n("Kr","Krypton",36,!1,"#5CB8D1",1.16,2.02,0,84);f.Rb=new n("Rb","Rubidium",37,!1,"#702EB0",2.2,3.03,0,85);f.Sr=new n("Sr","Strontium",38,!1,"#00FF00",1.95,2.49,0,88);f.Y=new n("Y","Yttrium",39,!1,"#94FFFF",1.9,0,0,89);f.Zr=new n("Zr","Zirconium",40,!1,"#94E0E0",1.75,0,0,90);f.Nb=new n("Nb","Niobium",41,!1,"#73C2C9",1.64,0,1,93);f.Mo=
new n("Mo","Molybdenum",42,!1,"#54B5B5",1.54,0,2,98);f.Tc=new n("Tc","Technetium",43,!1,"#3B9E9E",1.47,0,3,0);f.Ru=new n("Ru","Ruthenium",44,!1,"#248F8F",1.46,0,2,102);f.Rh=new n("Rh","Rhodium",45,!1,"#0A7D8C",1.42,0,1,103);f.Pd=new n("Pd","Palladium",46,!1,"#006985",1.39,1.63,0,106);f.Ag=new n("Ag","Silver",47,!1,"#C0C0C0",1.45,1.72,0,107);f.Cd=new n("Cd","Cadmium",48,!1,"#FFD98F",1.44,1.58,0,114);f.In=new n("In","Indium",49,!1,"#A67573",1.42,1.93,0,115);f.Sn=new n("Sn","Tin",50,!1,"#668080",1.39,
2.17,4,120);f.Sb=new n("Sb","Antimony",51,!1,"#9E63B5",1.39,2.06,3,121);f.Te=new n("Te","Tellurium",52,!0,"#D47A00",1.38,2.06,2,130);f.I=new n("I","Iodine",53,!0,"#940094",1.39,1.98,1,127);f.Xe=new n("Xe","Xenon",54,!1,"#429EB0",1.4,2.16,0,132);f.Cs=new n("Cs","Cesium",55,!1,"#57178F",2.44,3.43,0,133);f.Ba=new n("Ba","Barium",56,!1,"#00C900",2.15,2.68,0,138);f.La=new n("La","Lanthanum",57,!1,"#70D4FF",2.07,0,0,139);f.Ce=new n("Ce","Cerium",58,!1,"#FFFFC7",2.04,0,0,140);f.Pr=new n("Pr","Praseodymium",
59,!1,"#D9FFC7",2.03,0,0,141);f.Nd=new n("Nd","Neodymium",60,!1,"#C7FFC7",2.01,0,0,142);f.Pm=new n("Pm","Promethium",61,!1,"#A3FFC7",1.99,0,0,0);f.Sm=new n("Sm","Samarium",62,!1,"#8FFFC7",1.98,0,0,152);f.Eu=new n("Eu","Europium",63,!1,"#61FFC7",1.98,0,0,153);f.Gd=new n("Gd","Gadolinium",64,!1,"#45FFC7",1.96,0,0,158);f.Tb=new n("Tb","Terbium",65,!1,"#30FFC7",1.94,0,0,159);f.Dy=new n("Dy","Dysprosium",66,!1,"#1FFFC7",1.92,0,0,164);f.Ho=new n("Ho","Holmium",67,!1,"#00FF9C",1.92,0,0,165);f.Er=new n("Er",
"Erbium",68,!1,"#00E675",1.89,0,0,166);f.Tm=new n("Tm","Thulium",69,!1,"#00D452",1.9,0,0,169);f.Yb=new n("Yb","Ytterbium",70,!1,"#00BF38",1.87,0,0,174);f.Lu=new n("Lu","Lutetium",71,!1,"#00AB24",1.87,0,0,175);f.Hf=new n("Hf","Hafnium",72,!1,"#4DC2FF",1.75,0,0,180);f.Ta=new n("Ta","Tantalum",73,!1,"#4DA6FF",1.7,0,1,181);f.W=new n("W","Tungsten",74,!1,"#2194D6",1.62,0,2,184);f.Re=new n("Re","Rhenium",75,!1,"#267DAB",1.51,0,3,187);f.Os=new n("Os","Osmium",76,!1,"#266696",1.44,0,2,192);f.Ir=new n("Ir",
"Iridium",77,!1,"#175487",1.41,0,3,193);f.Pt=new n("Pt","Platinum",78,!1,"#D0D0E0",1.36,1.75,0,195);f.Au=new n("Au","Gold",79,!1,"#FFD123",1.36,1.66,1,197);f.Hg=new n("Hg","Mercury",80,!1,"#B8B8D0",1.32,1.55,0,202);f.Tl=new n("Tl","Thallium",81,!1,"#A6544D",1.45,1.96,0,205);f.Pb=new n("Pb","Lead",82,!1,"#575961",1.46,2.02,4,208);f.Bi=new n("Bi","Bismuth",83,!1,"#9E4FB5",1.48,2.07,3,209);f.Po=new n("Po","Polonium",84,!1,"#AB5C00",1.4,1.97,2,0);f.At=new n("At","Astatine",85,!0,"#754F45",1.5,2.02,1,
0);f.Rn=new n("Rn","Radon",86,!1,"#428296",1.5,2.2,0,0);f.Fr=new n("Fr","Francium",87,!1,"#420066",2.6,3.48,0,0);f.Ra=new n("Ra","Radium",88,!1,"#007D00",2.21,2.83,0,0);f.Ac=new n("Ac","Actinium",89,!1,"#70ABFA",2.15,0,0,0);f.Th=new n("Th","Thorium",90,!1,"#00BAFF",2.06,0,0,232);f.Pa=new n("Pa","Protactinium",91,!1,"#00A1FF",2,0,0,231);f.U=new n("U","Uranium",92,!1,"#008FFF",1.96,1.86,0,238);f.Np=new n("Np","Neptunium",93,!1,"#0080FF",1.9,0,0,0);f.Pu=new n("Pu","Plutonium",94,!1,"#006BFF",1.87,0,
0,0);f.Am=new n("Am","Americium",95,!1,"#545CF2",1.8,0,0,0);f.Cm=new n("Cm","Curium",96,!1,"#785CE3",1.69,0,0,0);f.Bk=new n("Bk","Berkelium",97,!1,"#8A4FE3",0,0,0,0);f.Cf=new n("Cf","Californium",98,!1,"#A136D4",0,0,0,0);f.Es=new n("Es","Einsteinium",99,!1,"#B31FD4",0,0,0,0);f.Fm=new n("Fm","Fermium",100,!1,"#B31FBA",0,0,0,0);f.Md=new n("Md","Mendelevium",101,!1,"#B30DA6",0,0,0,0);f.No=new n("No","Nobelium",102,!1,"#BD0D87",0,0,0,0);f.Lr=new n("Lr","Lawrencium",103,!1,"#C70066",0,0,0,0);f.Rf=new n("Rf",
"Rutherfordium",104,!1,"#CC0059",0,0,0,0);f.Db=new n("Db","Dubnium",105,!1,"#D1004F",0,0,0,0);f.Sg=new n("Sg","Seaborgium",106,!1,"#D90045",0,0,0,0);f.Bh=new n("Bh","Bohrium",107,!1,"#E00038",0,0,0,0);f.Hs=new n("Hs","Hassium",108,!1,"#E6002E",0,0,0,0);f.Mt=new n("Mt","Meitnerium",109,!1,"#EB0026",0,0,0,0);f.Ds=new n("Ds","Darmstadtium",110,!1,"#000000",0,0,0,0);f.Rg=new n("Rg","Roentgenium",111,!1,"#000000",0,0,0,0);f.Cn=new n("Cn","Copernicium",112,!1,"#000000",0,0,0,0);f.Nh=new n("Nh","Nihonium",
113,!1,"#000000",0,0,0,0);f.Fl=new n("Fl","Flerovium",114,!1,"#000000",0,0,0,0);f.Mc=new n("Mc","Moscovium",115,!1,"#000000",0,0,0,0);f.Lv=new n("Lv","Livermorium",116,!1,"#000000",0,0,0,0);f.Ts=new n("Ts","Tennessine",117,!1,"#000000",0,0,0,0);f.Og=new n("Og","Oganesson",118,!1,"#000000",0,0,0,0);f.H.pymolColor="#E6E6E6";f.C.pymolColor="#33FF33";f.N.pymolColor="#3333FF";f.O.pymolColor="#FF4D4D";f.F.pymolColor="#B3FFFF";f.S.pymolColor="#E6C640";return f}(ChemDoodle.SYMBOLS);
ChemDoodle.RESIDUE=function(f){function q(f,r,e,k,b,d){this.symbol=f;this.name=r;this.polar=e;this.aminoColor=k;this.shapelyColor=b;this.acidity=d}f=[];f.Ala=new q("Ala","Alanine",!1,"#C8C8C8","#8CFF8C",0);f.Arg=new q("Arg","Arginine",!0,"#145AFF","#00007C",1);f.Asn=new q("Asn","Asparagine",!0,"#00DCDC","#FF7C70",0);f.Asp=new q("Asp","Aspartic Acid",!0,"#E60A0A","#A00042",-1);f.Cys=new q("Cys","Cysteine",!0,"#E6E600","#FFFF70",0);f.Gln=new q("Gln","Glutamine",!0,"#00DCDC","#FF4C4C",0);f.Glu=new q("Glu",
"Glutamic Acid",!0,"#E60A0A","#660000",-1);f.Gly=new q("Gly","Glycine",!1,"#EBEBEB","#FFFFFF",0);f.His=new q("His","Histidine",!0,"#8282D2","#7070FF",1);f.Ile=new q("Ile","Isoleucine",!1,"#0F820F","#004C00",0);f.Leu=new q("Leu","Leucine",!1,"#0F820F","#455E45",0);f.Lys=new q("Lys","Lysine",!0,"#145AFF","#4747B8",1);f.Met=new q("Met","Methionine",!1,"#E6E600","#B8A042",0);f.Phe=new q("Phe","Phenylalanine",!1,"#3232AA","#534C52",0);f.Pro=new q("Pro","Proline",!1,"#DC9682","#525252",0);f.Ser=new q("Ser",
"Serine",!0,"#FA9600","#FF7042",0);f.Thr=new q("Thr","Threonine",!0,"#FA9600","#B84C00",0);f.Trp=new q("Trp","Tryptophan",!0,"#B45AB4","#4F4600",0);f.Tyr=new q("Tyr","Tyrosine",!0,"#3232AA","#8C704C",0);f.Val=new q("Val","Valine",!1,"#0F820F","#FF8CFF",0);f.Asx=new q("Asx","Asparagine/Aspartic Acid",!0,"#FF69B4","#FF00FF",0);f.Glx=new q("Glx","Glutamine/Glutamic Acid",!0,"#FF69B4","#FF00FF",0);f["*"]=new q("*","Other",!1,"#BEA06E","#FF00FF",0);f.A=new q("A","Adenine",!1,"#BEA06E","#A0A0FF",0);f.G=
new q("G","Guanine",!1,"#BEA06E","#FF7070",0);f.I=new q("I","",!1,"#BEA06E","#80FFFF",0);f.C=new q("C","Cytosine",!1,"#BEA06E","#FF8C4B",0);f.T=new q("T","Thymine",!1,"#BEA06E","#A0FFA0",0);f.U=new q("U","Uracil",!1,"#BEA06E","#FF8080",0);return f}();
(function(f,q){f.Queue=function(){this.queue=[]};f=f.Queue.prototype;f.queueSpace=0;f.getSize=function(){return this.queue.length-this.queueSpace};f.isEmpty=function(){return 0===this.queue.length};f.enqueue=function(f){this.queue.push(f)};f.dequeue=function(){let f;this.queue.length&&(f=this.queue[this.queueSpace],2*++this.queueSpace>=this.queue.length&&(this.queue=this.queue.slice(this.queueSpace),this.queueSpace=0));return f};f.getOldestElement=function(){let f;this.queue.length&&(f=this.queue[this.queueSpace]);
return f}})(ChemDoodle.structures);
(function(f,q,n){f.Point=function(f,e){this.x=f?f:0;this.y=e?e:0};f=f.Point.prototype;f.sub=function(f){this.x-=f.x;this.y-=f.y};f.add=function(f){this.x+=f.x;this.y+=f.y};f.distance=function(f){let e=f.x-this.x;f=f.y-this.y;return q.sqrt(e*e+f*f)};f.angleForStupidCanvasArcs=function(f){var e=f.x-this.x;f=f.y-this.y;for(e=0===e?0===f?0:0<f?q.PI/2:3*q.PI/2:0===f?0<e?0:q.PI:0>e?q.atan(f/e)+q.PI:0>f?q.atan(f/e)+2*q.PI:q.atan(f/e);0>e;)e+=2*q.PI;return e%=2*q.PI};f.angle=function(f){var e=f.x-this.x;
f=this.y-f.y;for(e=0===e?0===f?0:0<f?q.PI/2:3*q.PI/2:0===f?0<e?0:q.PI:0>e?q.atan(f/e)+q.PI:0>f?q.atan(f/e)+2*q.PI:q.atan(f/e);0>e;)e+=2*q.PI;return e%=2*q.PI}})(ChemDoodle.structures,Math);
(function(f,q,n,r){let e=/[ ,]+/,k=/\-+/,b=["Helvetica","Arial","Dialog"];q.Query=function(b){this.type=b;this.elements={v:[],not:!1};this.saturation=this.hydrogens=this.connectivityNoH=this.connectivity=this.chirality=this.charge=r;this.orders={v:[],not:!1};this.cache=this.ringCount=this.aromatic=this.stereo=r};q.Query.TYPE_ATOM=0;q.Query.TYPE_BOND=1;n=q.Query.prototype;n.parseRange=function(b){let d=[];b=b.split(e);for(let h=0,e=b.length;h<e;h++){var a=b[h],g=!1,l=!1;"-"===a.charAt(0)&&(g=!0,a=
a.substring(1));-1!=a.indexOf("--")&&(l=!0);-1!=a.indexOf("-")?(a=a.split(k),g={x:parseInt(a[0])*(g?-1:1),y:parseInt(a[1])*(l?-1:1)},g.y<g.x&&(l=g.y,g.y=g.x,g.x=l),d.push(g)):d.push({x:parseInt(a)*(g?-1:1)})}return d};n.draw=function(d,h,a){this.cache||(this.cache=this.toString());let g=this.cache,e=r;var v=g.indexOf("(");-1!=v&&(g=this.cache.substring(0,v),e=this.cache.substring(v,this.cache.length));d.textAlign="center";d.textBaseline="middle";d.font=f.getFontString(12,b,!0,!1);v=d.measureText(g).width;
d.fillStyle=h.backgroundColor;d.fillRect(a.x-v/2,a.y-6,v,12);d.fillStyle="black";d.fillText(g,a.x,a.y);e&&(d.font=f.getFontString(10,b,!1,!0),v=d.measureText(e).width,d.fillStyle=h.backgroundColor,d.fillRect(a.x-v/2,a.y+6,v,11),d.fillStyle="black",d.fillText(e,a.x,a.y+11))};n.outputRange=function(b){let d=!1,a=[];for(let g=0,h=b.length;g<h;g++){d&&a.push(",");d=!0;let h=b[g];h.y?(a.push(h.x),a.push("-"),a.push(h.y)):a.push(h.x)}return a.join("")};n.toString=function(){let b=[],h=[];this.type===q.Query.TYPE_ATOM?
(this.elements&&0!==this.elements.v.length?(this.elements.not&&b.push("!"),b.push("["),b.push(this.elements.v.join(",")),b.push("]")):b.push("[a]"),this.chirality&&h.push((this.chirality.not?"!":"")+"@\x3d"+this.chirality.v),this.aromatic&&h.push((this.aromatic.not?"!":"")+"A"),this.charge&&h.push((this.charge.not?"!":"")+"C\x3d"+this.outputRange(this.charge.v)),this.hydrogens&&h.push((this.hydrogens.not?"!":"")+"H\x3d"+this.outputRange(this.hydrogens.v)),this.ringCount&&h.push((this.ringCount.not?
"!":"")+"R\x3d"+this.outputRange(this.ringCount.v)),this.saturation&&h.push((this.saturation.not?"!":"")+"S"),this.connectivity&&h.push((this.connectivity.not?"!":"")+"X\x3d"+this.outputRange(this.connectivity.v)),this.connectivityNoH&&h.push((this.connectivityNoH.not?"!":"")+"x\x3d"+this.outputRange(this.connectivityNoH.v))):this.type===q.Query.TYPE_BOND&&(this.orders&&0!==this.orders.v.length?(this.orders.not&&b.push("!"),b.push("["),b.push(this.orders.v.join(",")),b.push("]")):b.push("[a]"),this.stereo&&
h.push((this.stereo.not?"!":"")+"@\x3d"+this.stereo.v),this.aromatic&&h.push((this.aromatic.not?"!":"")+"A"),this.ringCount&&h.push((this.ringCount.not?"!":"")+"R\x3d"+this.outputRange(this.ringCount.v)));0<h.length&&(b.push("("),b.push(h.join(",")),b.push(")"));return b.join("")}})(ChemDoodle.extensions,ChemDoodle.structures,Math);
(function(f,q,n,r,e,k,b){let d=/\s+/g;r.Atom=function(a,b,d,h){this.label=a?a.trim():"C";this.x=b?b:0;this.y=d?d:0;this.z=h?h:0};let h=r.Atom.prototype=new r.Point(0,0);h.charge=0;h.numLonePair=0;h.numRadical=0;h.mass=-1;h.implicitH=-1;h.coordinationNumber=0;h.bondNumber=0;h.angleOfLeastInterference=0;h.isHidden=!1;h.altLabel=b;h.isLone=!1;h.isHover=!1;h.isSelected=!1;h.add3D=function(a){this.x+=a.x;this.y+=a.y;this.z+=a.z};h.sub3D=function(a){this.x-=a.x;this.y-=a.y;this.z-=a.z};h.distance3D=function(a){let b=
a.x-this.x,d=a.y-this.y;a=a.z-this.z;return e.sqrt(b*b+d*d+a*a)};h.draw=function(a,g){if(!this.dontDraw){if(this.isLassoed){var h=a.createRadialGradient(this.x-1,this.y-1,0,this.x,this.y,7);h.addColorStop(0,"rgba(212, 99, 0, 0)");h.addColorStop(.7,"rgba(212, 99, 0, 0.8)");a.fillStyle=h;a.beginPath();a.arc(this.x,this.y,5,0,2*e.PI,!1);a.fill()}if(!this.query){this.textBounds=[];this.styles&&(g=this.styles);var v=q.getFontString(g.atoms_font_size_2D,g.atoms_font_families_2D,g.atoms_font_bold_2D,g.atoms_font_italic_2D);
a.font=v;a.fillStyle=this.getElementColor(g.atoms_useJMOLColors,g.atoms_usePYMOLColors,g.atoms_color,2);"H"===this.label&&g.atoms_HBlack_2D&&(a.fillStyle="black");this.error&&(a.fillStyle=g.colorError);h=this.isLabelVisible(g);if(this.isLone&&!h||g.atoms_circles_2D)this.isLone&&(a.fillStyle="#909090"),a.beginPath(),a.arc(this.x,this.y,g.atoms_circleDiameter_2D/2,0,2*e.PI,!1),a.fill(),0<g.atoms_circleBorderWidth_2D&&(a.lineWidth=g.atoms_circleBorderWidth_2D,a.strokeStyle="black",a.stroke());else if(h)if(a.textAlign=
"center",a.textBaseline="middle",this.altLabel!==b)a.fillText(this.altLabel,this.x,this.y),h=a.measureText(this.altLabel).width,this.textBounds.push({x:this.x-h/2,y:this.y-g.atoms_font_size_2D/2+1,w:h,h:g.atoms_font_size_2D-2});else if(f[this.label]){a.fillText(this.label,this.x,this.y);var m=a.measureText(this.label).width;this.textBounds.push({x:this.x-m/2,y:this.y-g.atoms_font_size_2D/2+1,w:m,h:g.atoms_font_size_2D-2});var k=0;-1!==this.mass&&(h=a.font,a.font=q.getFontString(.7*g.atoms_font_size_2D,
g.atoms_font_families_2D,g.atoms_font_bold_2D,g.atoms_font_italic_2D),k=a.measureText(this.mass).width,a.fillText(this.mass,this.x-k-.5,this.y-g.atoms_font_size_2D/2+1),this.textBounds.push({x:this.x-m/2-k-.5,y:this.y-1.7*g.atoms_font_size_2D/2+1,w:k,h:g.atoms_font_size_2D/2-1}),a.font=h);h=m/2;var u=this.getImplicitHydrogenCount();if(g.atoms_implicitHydrogens_2D&&0<u){var w=0;var z=a.measureText("H").width;let b=!0;if(1<u){let c=m/2+z/2,d=0,h=q.getFontString(.8*g.atoms_font_size_2D,g.atoms_font_families_2D,
g.atoms_font_bold_2D,g.atoms_font_italic_2D);a.font=h;let l=a.measureText(u).width;1===this.bondNumber?this.angleOfLeastInterference>e.PI/2&&this.angleOfLeastInterference<3*e.PI/2&&(c=-m/2-l-z/2-k/2,b=!1,w=e.PI):this.angleOfLeastInterference<=e.PI/4||(this.angleOfLeastInterference<3*e.PI/4?(c=0,d=.9*-g.atoms_font_size_2D,0!==this.charge&&(d-=.3*g.atoms_font_size_2D),b=!1,w=e.PI/2):this.angleOfLeastInterference<=5*e.PI/4?(c=-m/2-l-z/2-k/2,b=!1,w=e.PI):this.angleOfLeastInterference<7*e.PI/4&&(c=0,d=
.9*g.atoms_font_size_2D,b=!1,w=3*e.PI/2));a.font=v;a.fillText("H",this.x+c,this.y+d);a.font=h;a.fillText(u,this.x+c+z/2+l/2,this.y+d+.3*g.atoms_font_size_2D);this.textBounds.push({x:this.x+c-z/2,y:this.y+d-g.atoms_font_size_2D/2+1,w:z,h:g.atoms_font_size_2D-2});this.textBounds.push({x:this.x+c+z/2,y:this.y+d+.3*g.atoms_font_size_2D-g.atoms_font_size_2D/2+1,w:l,h:.8*g.atoms_font_size_2D-2})}else v=m/2+z/2,u=0,1===this.bondNumber?this.angleOfLeastInterference>e.PI/2&&this.angleOfLeastInterference<3*
e.PI/2&&(v=-m/2-z/2-k/2,b=!1,w=e.PI):this.angleOfLeastInterference<=e.PI/4||(this.angleOfLeastInterference<3*e.PI/4?(v=0,u=.9*-g.atoms_font_size_2D,b=!1,w=e.PI/2):this.angleOfLeastInterference<=5*e.PI/4?(v=-m/2-z/2-k/2,b=!1,w=e.PI):this.angleOfLeastInterference<7*e.PI/4&&(v=0,u=.9*g.atoms_font_size_2D,b=!1,w=3*e.PI/2)),a.fillText("H",this.x+v,this.y+u),this.textBounds.push({x:this.x+v-z/2,y:this.y+u-g.atoms_font_size_2D/2+1,w:z,h:g.atoms_font_size_2D-2});b&&(h+=z)}0!==this.charge&&(m=this.charge.toFixed(0),
m="1"===m?"+":"-1"===m?"\u2013":m.startsWith("-")?m.substring(1)+"\u2013":m+"+",k=a.measureText(m).width,h+=k/2,a.textAlign="center",a.textBaseline="middle",a.font=q.getFontString(e.floor(.8*g.atoms_font_size_2D),g.atoms_font_families_2D,g.atoms_font_bold_2D,g.atoms_font_italic_2D),a.fillText(m,this.x+h-1,this.y-g.atoms_font_size_2D/2+1),this.textBounds.push({x:this.x+h-k/2-1,y:this.y-1.8*g.atoms_font_size_2D/2+5,w:k,h:g.atoms_font_size_2D/2-1}))}else r.CondensedLabel?this.label.match(d)?(a.textAlign=
"left",this.error&&(a.fillStyle=g.colorError),a.fillText(this.label,this.x,this.y),h=a.measureText(this.label).width,this.textBounds.push({x:this.x+1,y:this.y-g.atoms_font_size_2D/2+1,w:h,h:g.atoms_font_size_2D-2})):(this.condensed&&this.condensed.text===this.label||(this.condensed=new r.CondensedLabel(this,this.label)),this.condensed.draw(a,g)):(a.fillText(this.label,this.x,this.y),h=a.measureText(this.label).width,this.textBounds.push({x:this.x-h/2,y:this.y-g.atoms_font_size_2D/2+1,w:h,h:g.atoms_font_size_2D-
2}));if(0<this.numLonePair||0<this.numRadical){a.fillStyle="black";m=this.angles.slice(0);h=this.angleOfLeastInterference;k=this.largestAngle;w!==b&&(m.push(w),m.sort(function(a,c){return a-c}),k=n.angleBetweenLargest(m),h=k.angle%(2*e.PI),k=k.largest);v=[];for(z=0;z<this.numLonePair;z++)v.push({t:2});for(z=0;z<this.numRadical;z++)v.push({t:1});if(w===b&&e.abs(k-2*e.PI/m.length)<e.PI/60){m=e.ceil(v.length/m.length);for(let b=0,c=v.length;b<c;b+=m,h+=k)this.drawElectrons(a,g,v.slice(b,e.min(v.length,
b+m)),h,k,w)}else this.drawElectrons(a,g,v,h,k,w)}}}};h.drawElectrons=function(a,d,h,f,m,k){k=m/(h.length+(0===this.bonds.length&&k===b?0:1));f=f-m/2+k;for(m=0;m<h.length;m++){var g=h[m],l=f+m*k;let b=this.x+Math.cos(l)*d.atoms_lonePairDistance_2D,v=this.y-Math.sin(l)*d.atoms_lonePairDistance_2D;2===g.t?(l+=Math.PI/2,g=Math.cos(l)*d.atoms_lonePairSpread_2D/2,l=-Math.sin(l)*d.atoms_lonePairSpread_2D/2,a.beginPath(),a.arc(b+g,v+l,d.atoms_lonePairDiameter_2D,0,2*e.PI,!1),a.fill(),a.beginPath(),a.arc(b-
g,v-l,d.atoms_lonePairDiameter_2D,0,2*e.PI,!1),a.fill()):1===g.t&&(a.beginPath(),a.arc(b,v,d.atoms_lonePairDiameter_2D,0,2*e.PI,!1),a.fill())}};h.drawDecorations=function(a,b){if(this.isHover||this.isSelected)a.strokeStyle=this.isHover?b.colorHover:b.colorSelect,a.lineWidth=1.2,a.beginPath(),a.arc(this.x,this.y,this.isHover?7:15,0,2*e.PI,!1),a.stroke();this.isOverlap&&(a.strokeStyle=b.colorError,a.lineWidth=1.2,a.beginPath(),a.arc(this.x,this.y,7,0,2*e.PI,!1),a.stroke())};h.render=function(a,b,d){this.styles&&
(b=this.styles);let g=k.translate(k.identity(),[this.x,this.y,this.z]),h=b.atoms_useVDWDiameters_3D?f[this.label].vdWRadius*b.atoms_vdwMultiplier_3D:b.atoms_sphereDiameter_3D/2;0===h&&(h=1);k.scale(g,[h,h,h]);d||(d=b.atoms_color,b.atoms_useJMOLColors?d=f[this.label].jmolColor:b.atoms_usePYMOLColors&&(d=f[this.label].pymolColor),a.material.setDiffuseColor(a,d));a.shader.setMatrixUniforms(a,g);a.drawElements(a.TRIANGLES,(this.renderAsStar?a.starBuffer:a.sphereBuffer).vertexIndexBuffer.numItems,a.UNSIGNED_SHORT,
0)};h.renderHighlight=function(a,b){if(this.isSelected||this.isHover){this.styles&&(b=this.styles);let d=k.translate(k.identity(),[this.x,this.y,this.z]),g=b.atoms_useVDWDiameters_3D?f[this.label].vdWRadius*b.atoms_vdwMultiplier_3D:b.atoms_sphereDiameter_3D/2;0===g&&(g=1);g*=1.3;k.scale(d,[g,g,g]);a.shader.setMatrixUniforms(a,d);a.material.setDiffuseColor(a,this.isHover?b.colorHover:b.colorSelect);a.drawElements(a.TRIANGLES,(this.renderAsStar?a.starBuffer:a.sphereBuffer).vertexIndexBuffer.numItems,
a.UNSIGNED_SHORT,0)}};h.isLabelVisible=function(a){return a.atoms_displayAllCarbonLabels_2D||"C"!==this.label||this.altLabel||!f[this.label]||-1!==this.mass||-1!==this.implicitH||0!==this.charge||a.atoms_showAttributedCarbons_2D&&(0!==this.numRadical||0!==this.numLonePair)||this.isHidden&&a.atoms_showHiddenCarbons_2D||a.atoms_displayTerminalCarbonLabels_2D&&1===this.bondNumber?!0:!1};h.getImplicitHydrogenCount=function(){if(!f[this.label]||!f[this.label].addH)return 0;if(-1!==this.implicitH)return this.implicitH;
if("H"===this.label)return 0;var a=f[this.label].valency;let b=a-this.coordinationNumber;0<this.numRadical&&(b=e.max(0,b-this.numRadical));0<this.charge?(a=4-a,b=this.charge<=a?b+this.charge:4-this.coordinationNumber-this.charge+a):b+=this.charge;return 0>b?0:e.floor(b)};h.getBounds=function(){let a=new n.Bounds;a.expand(this.x,this.y);if(this.textBounds)for(let b=0,d=this.textBounds.length;b<d;b++){let d=this.textBounds[b];a.expand(d.x,d.y,d.x+d.w,d.y+d.h)}return a};h.getBounds3D=function(){let a=
new n.Bounds;a.expand3D(this.x,this.y,this.z);return a};h.getElementColor=function(a,b,d){if(!f[this.label])return"#000";a?d=f[this.label].jmolColor:b&&(d=f[this.label].pymolColor);return d}})(ChemDoodle.ELEMENT,ChemDoodle.extensions,ChemDoodle.math,ChemDoodle.structures,Math,ChemDoodle.lib.mat4);
(function(f,q,n,r,e,k,b,d){n.Bond=function(b,a,g){this.a1=b;this.a2=a;this.bondOrder=g!==d?g:1};n.Bond.STEREO_NONE="none";n.Bond.STEREO_PROTRUDING="protruding";n.Bond.STEREO_RECESSED="recessed";n.Bond.STEREO_AMBIGUOUS="ambiguous";f=n.Bond.prototype;f.stereo=n.Bond.STEREO_NONE;f.isHover=!1;f.ring=d;f.getCenter=function(){return new n.Point((this.a1.x+this.a2.x)/2,(this.a1.y+this.a2.y)/2)};f.getLength=function(){return this.a1.distance(this.a2)};f.getLength3D=function(){return this.a1.distance3D(this.a2)};
f.contains=function(b){return b===this.a1||b===this.a2};f.getNeighbor=function(b){return b===this.a1?this.a2:b===this.a2?this.a1:d};f.draw=function(b,a){if(this.a1.x!==this.a2.x||this.a1.y!==this.a2.y){this.styles&&(a=this.styles);var d=this.a1.x,h=this.a2.x,f=this.a1.y,m=this.a2.y,k=this.a1.distance(this.a2),u=h-d,w=m-f;if(this.a1.isLassoed&&this.a2.isLassoed){let a=b.createLinearGradient(d,f,h,m);a.addColorStop(0,"rgba(212, 99, 0, 0)");a.addColorStop(.5,"rgba(212, 99, 0, 0.8)");a.addColorStop(1,
"rgba(212, 99, 0, 0)");let g=this.a1.angle(this.a2)+e.PI/2,c=e.cos(g),l=e.sin(g),k=d-2.5*c,v=f+2.5*l,u=d+2.5*c,x=f-2.5*l,w=h+2.5*c,r=m-2.5*l,n=h-2.5*c,q=m+2.5*l;b.fillStyle=a;b.beginPath();b.moveTo(k,v);b.lineTo(u,x);b.lineTo(w,r);b.lineTo(n,q);b.closePath();b.fill()}if(a.atoms_display&&!a.atoms_circles_2D&&this.a1.isLabelVisible(a)&&this.a1.textBounds){let b=0;for(let a=0,d=this.a1.textBounds.length;a<d;a++)b=Math.max(b,r.calculateDistanceInterior(this.a1,this.a2,this.a1.textBounds[a]));b+=a.bonds_atomLabelBuffer_2D;
let g=b/k;d+=u*g;f+=w*g}if(a.atoms_display&&!a.atoms_circles_2D&&this.a2.isLabelVisible(a)&&this.a2.textBounds){let b=0;for(let a=0,d=this.a2.textBounds.length;a<d;a++)b=Math.max(b,r.calculateDistanceInterior(this.a2,this.a1,this.a2.textBounds[a]));b+=a.bonds_atomLabelBuffer_2D;let d=b/k;h-=u*d;m-=w*d}if(a.bonds_clearOverlaps_2D){let g=d+.15*u,e=f+.15*w,c=h-.15*u,l=m-.15*w;b.strokeStyle=a.backgroundColor;b.lineWidth=a.bonds_width_2D+2*a.bonds_overlapClearWidth_2D;b.lineCap="round";b.beginPath();b.moveTo(g,
e);b.lineTo(c,l);b.closePath();b.stroke()}b.strokeStyle=this.error?a.colorError:a.bonds_color;b.fillStyle=this.error?a.colorError:a.bonds_color;b.lineWidth=a.bonds_width_2D;b.lineCap=a.bonds_ends_2D;if(a.bonds_splitColor){let g=b.createLinearGradient(d,f,h,m),e=this.a1.styles?this.a1.styles:a,c=this.a2.styles?this.a2.styles:a,l=this.a1.getElementColor(e.atoms_useJMOLColors,e.atoms_usePYMOLColors,e.atoms_color,2),k=this.a2.getElementColor(c.atoms_useJMOLColors,c.atoms_usePYMOLColors,c.atoms_color,
2);g.addColorStop(0,l);a.bonds_colorGradient||(g.addColorStop(.5,l),g.addColorStop(.51,k));g.addColorStop(1,k);b.strokeStyle=g;b.fillStyle=g}if(a.bonds_lewisStyle_2D&&0===this.bondOrder%1)this.drawLewisStyle(b,a,d,f,h,m);else switch(this.query?1:this.bondOrder){case 0:{let g=h-d,l=m-f,c=e.sqrt(g*g+l*l),k=e.floor(c/a.bonds_dotSize_2D),v=(c-(k-1)*a.bonds_dotSize_2D)/2;1===k%2?v+=a.bonds_dotSize_2D/4:(v-=a.bonds_dotSize_2D/4,k+=2);k/=2;let u=this.a1.angle(this.a2),x=d+v*Math.cos(u),w=f-v*Math.sin(u);
b.beginPath();for(let c=0;c<k;c++)b.arc(x,w,a.bonds_dotSize_2D/2,0,2*e.PI,!1),x+=2*a.bonds_dotSize_2D*Math.cos(u),w-=2*a.bonds_dotSize_2D*Math.sin(u);b.fill();break}case .5:b.beginPath();b.moveTo(d,f);b.lineTo(h,m);b.setLineDash([a.bonds_hashSpacing_2D,a.bonds_hashSpacing_2D]);b.stroke();b.setLineDash([]);break;case 1:if(this.query||this.stereo!==n.Bond.STEREO_PROTRUDING&&this.stereo!==n.Bond.STEREO_RECESSED)if(this.query||this.stereo!==n.Bond.STEREO_AMBIGUOUS)b.beginPath(),b.moveTo(d,f),b.lineTo(h,
m),b.stroke(),this.query&&this.query.draw(b,a,this.getCenter());else{let g=h-d,l=m-f;b.beginPath();b.moveTo(d,f);let c=e.floor(e.sqrt(g*g+l*l)/a.bonds_wavyLength_2D),k=d,v=f,u=this.a1.angle(this.a2)+e.PI/2,x=e.cos(u),w=e.sin(u),r=g/c,n=l/c,q,J;for(let d=0;d<c;d++){k+=r;v+=n;let c=0===d%2?1:-1;q=a.bonds_wavyLength_2D*x*c+k-.5*r;J=a.bonds_wavyLength_2D*-w*c+v-.5*n;b.quadraticCurveTo(q,J,k,v)}b.stroke()}else{let g=a.bonds_width_2D/2,l=a.bonds_wedgeThickness_2D/2,c=this.a1.angle(this.a2)+e.PI/2,k=e.cos(c),
v=e.sin(c),u=d-k*g,x=f+v*g,w=d+k*g,r=f-v*g,q=h+k*l,G=m-v*l,J=h-k*l,H=m+v*l;b.beginPath();b.moveTo(u,x);b.lineTo(w,r);b.lineTo(q,G);b.lineTo(J,H);b.closePath();this.stereo===n.Bond.STEREO_PROTRUDING?b.fill():(b.save(),b.clip(),b.lineWidth=2*l,b.lineCap="butt",b.beginPath(),b.moveTo(d,f),b.lineTo(h+5*(h-d),m+5*(m-f)),b.setLineDash([a.bonds_hashWidth_2D,a.bonds_hashSpacing_2D]),b.stroke(),b.setLineDash([]),b.restore())}break;case 1.5:case 2:{let g=this.a1.angle(this.a2),l=g+e.PI/2,c=e.cos(l),k=e.sin(l),
v=this.a1.distance(this.a2),u=a.bonds_useAbsoluteSaturationWidths_2D?a.bonds_saturationWidthAbs_2D/2:v*a.bonds_saturationWidth_2D/2;if(this.stereo===n.Bond.STEREO_AMBIGUOUS){let a=d-c*u,g=f+k*u,e=d+c*u,l=f-k*u,v=h+c*u,x=m-k*u,p=h-c*u,w=m+k*u;b.beginPath();b.moveTo(a,g);b.lineTo(v,x);b.moveTo(e,l);b.lineTo(p,w);b.stroke()}else if(!a.bonds_symmetrical_2D&&(this.ring||"C"===this.a1.label&&"C"===this.a2.label)){b.beginPath();b.moveTo(d,f);b.lineTo(h,m);b.stroke();let l=0;u*=2;let x=a.bonds_saturationAngle_2D;
x<e.PI/2&&(l=-(u/e.tan(x)));if(e.abs(l)<v/2){let v=d-e.cos(g)*l,x=h+e.cos(g)*l,p=f+e.sin(g)*l,w=m-e.sin(g)*l,r=v-c*u,n=p+k*u,z=v+c*u,q=p-k*u,y=x-c*u,B=w+k*u,A=x+c*u,C=w-k*u,D=!this.ring||this.ring.center.angle(this.a1)>this.ring.center.angle(this.a2)&&!(this.ring.center.angle(this.a1)-this.ring.center.angle(this.a2)>e.PI)||this.ring.center.angle(this.a1)-this.ring.center.angle(this.a2)<-e.PI;b.beginPath();D?(b.moveTo(r,n),b.lineTo(y,B)):(b.moveTo(z,q),b.lineTo(A,C));2!==this.bondOrder&&b.setLineDash([a.bonds_hashSpacing_2D,
a.bonds_hashSpacing_2D]);b.stroke();b.setLineDash([])}}else{let g=d-c*u,e=f+k*u,l=d+c*u,v=f-k*u,x=h+c*u,p=m-k*u,w=h-c*u,r=m+k*u;b.beginPath();b.moveTo(g,e);b.lineTo(w,r);b.stroke();b.beginPath();b.moveTo(l,v);b.lineTo(x,p);2!==this.bondOrder&&b.setLineDash([a.bonds_hashWidth_2D,a.bonds_hashSpacing_2D]);b.stroke();b.setLineDash([])}break}case 3:{let g=a.bonds_useAbsoluteSaturationWidths_2D?a.bonds_saturationWidthAbs_2D:this.a1.distance(this.a2)*a.bonds_saturationWidth_2D,l=this.a1.angle(this.a2)+e.PI/
2,c=e.cos(l),k=e.sin(l),v=d-c*g,u=f+k*g,x=d+c*g,w=f-k*g,r=h+c*g,n=m-k*g,q=h-c*g,J=m+k*g;b.beginPath();b.moveTo(v,u);b.lineTo(q,J);b.moveTo(x,w);b.lineTo(r,n);b.moveTo(d,f);b.lineTo(h,m);b.stroke()}}}};f.drawDecorations=function(b,a){if(this.isHover||this.isSelected){let d=2*e.PI,h=(this.a1.angleForStupidCanvasArcs(this.a2)+e.PI/2)%d;b.strokeStyle=this.isHover?a.colorHover:a.colorSelect;b.lineWidth=1.2;b.beginPath();a=(h+e.PI)%d;a%=2*e.PI;b.arc(this.a1.x,this.a1.y,7,h,a,!1);b.stroke();b.beginPath();
h+=e.PI;a=(h+e.PI)%d;b.arc(this.a2.x,this.a2.y,7,h,a,!1);b.stroke()}};f.drawLewisStyle=function(b,a,d,l,f,m){var g=this.a1.angle(this.a2);let h=g+e.PI/2;f-=d;m-=l;f=e.sqrt(f*f+m*m)/(this.bondOrder+1);m=f*e.cos(g);g=-f*e.sin(g);d+=m;l+=g;for(f=0;f<this.bondOrder;f++){var k=a.atoms_lonePairSpread_2D/2;let f=d-e.cos(h)*k,v=l+e.sin(h)*k,c=d+e.cos(h)*k;k=l-e.sin(h)*k;b.beginPath();b.arc(f-a.atoms_lonePairDiameter_2D/2,v-a.atoms_lonePairDiameter_2D/2,a.atoms_lonePairDiameter_2D,0,2*e.PI,!1);b.fill();b.beginPath();
b.arc(c-a.atoms_lonePairDiameter_2D/2,k-a.atoms_lonePairDiameter_2D/2,a.atoms_lonePairDiameter_2D,0,2*e.PI,!1);b.fill();d+=m;l+=g}};f.render=function(d,a,g){this.styles&&(a=this.styles);var h=this.a1.distance3D(this.a2);if(0!==h){var f=a.bonds_cylinderDiameter_3D/2,m=a.bonds_color,x=k.translate(k.identity(),[this.a1.x,this.a1.y,this.a1.z]),u,w=[this.a2.x-this.a1.x,this.a2.y-this.a1.y,this.a2.z-this.a1.z],r=[0,1,0],n=0;this.a1.x===this.a2.x&&this.a1.z===this.a2.z?(r=[0,0,1],this.a2.y<this.a1.y&&(n=
e.PI)):(n=q.vec3AngleFrom(r,w),r=b.cross(r,w,[]));if(a.bonds_splitColor){m=this.a1.styles?this.a1.styles:a;var c=this.a2.styles?this.a2.styles:a;m=this.a1.getElementColor(m.atoms_useJMOLColors,m.atoms_usePYMOLColors,m.atoms_color);c=this.a2.getElementColor(c.atoms_useJMOLColors,c.atoms_usePYMOLColors,c.atoms_color);m!=c&&(u=k.translate(k.identity(),[this.a2.x,this.a2.y,this.a2.z]))}var p=[0];if(g){if(a.bonds_showBondOrders_3D&&1<this.bondOrder){p=[a.bonds_cylinderDiameter_3D];var A=[0,0,1];f=k.inverse(d.rotationMatrix,
[]);k.multiplyVec3(f,A);A=b.cross(w,A,[]);b.normalize(A)}w=1;var C=a.bonds_pillSpacing_3D;f=a.bonds_pillHeight_3D;0==this.bondOrder&&(a.bonds_renderAsLines_3D?f=C:(f=a.bonds_pillDiameter_3D,f<a.bonds_cylinderDiameter_3D&&(f/=2),w=f/2,h/=w,C/=w/2));g=f+C;let l=e.floor(h/g);h=(C+a.bonds_pillDiameter_3D+(h-g*l))/2;C=l;u&&(C=e.floor(l/2));for(let v=0,z=p.length;v<z;v++){let z=k.set(x,[]);0!==p[v]&&k.translate(z,b.scale(A,p[v],[]));0!==n&&k.rotate(z,n,r);1!=w&&k.scale(z,[w,w,w]);m&&d.material.setDiffuseColor(d,
m);k.translate(z,[0,h,0]);for(var B=0;B<C;B++)a.bonds_renderAsLines_3D?0==this.bondOrder?(d.shader.setMatrixUniforms(d,z),d.drawArrays(d.POINTS,0,1)):(k.scale(z,[1,f,1]),d.shader.setMatrixUniforms(d,z),d.drawArrays(d.LINES,0,d.lineBuffer.vertexPositionBuffer.numItems),k.scale(z,[1,1/f,1])):(d.shader.setMatrixUniforms(d,z),0==this.bondOrder?d.drawElements(d.TRIANGLES,d.sphereBuffer.vertexIndexBuffer.numItems,d.UNSIGNED_SHORT,0):d.drawElements(d.TRIANGLES,d.pillBuffer.vertexIndexBuffer.numItems,d.UNSIGNED_SHORT,
0)),k.translate(z,[0,g,0]);if(u){let m;a.bonds_renderAsLines_3D?(B=f,B/=2,m=0):(B=2/3,m=(1-B)/2);0!=l%2&&(k.scale(z,[1,B,1]),d.shader.setMatrixUniforms(d,z),a.bonds_renderAsLines_3D?0==this.bondOrder?d.drawArrays(d.POINTS,0,1):d.drawArrays(d.LINES,0,d.lineBuffer.vertexPositionBuffer.numItems):0==this.bondOrder?d.drawElements(d.TRIANGLES,d.sphereBuffer.vertexIndexBuffer.numItems,d.UNSIGNED_SHORT,0):d.drawElements(d.TRIANGLES,d.pillBuffer.vertexIndexBuffer.numItems,d.UNSIGNED_SHORT,0),k.translate(z,
[0,g*(1+m),0]),k.scale(z,[1,1/B,1]));k.set(u,z);0!==p[v]&&k.translate(z,b.scale(A,p[v],[]));k.rotate(z,n+e.PI,r);1!=w&&k.scale(z,[w,w,w]);c&&d.material.setDiffuseColor(d,c);k.translate(z,[0,h,0]);for(let b=0;b<C;b++)a.bonds_renderAsLines_3D?0==this.bondOrder?(d.shader.setMatrixUniforms(d,z),d.drawArrays(d.POINTS,0,1)):(k.scale(z,[1,f,1]),d.shader.setMatrixUniforms(d,z),d.drawArrays(d.LINES,0,d.lineBuffer.vertexPositionBuffer.numItems),k.scale(z,[1,1/f,1])):(d.shader.setMatrixUniforms(d,z),0==this.bondOrder?
d.drawElements(d.TRIANGLES,d.sphereBuffer.vertexIndexBuffer.numItems,d.UNSIGNED_SHORT,0):d.drawElements(d.TRIANGLES,d.pillBuffer.vertexIndexBuffer.numItems,d.UNSIGNED_SHORT,0)),k.translate(z,[0,g,0]);0!=l%2&&(k.scale(z,[1,B,1]),d.shader.setMatrixUniforms(d,z),a.bonds_renderAsLines_3D?0==this.bondOrder?d.drawArrays(d.POINTS,0,1):d.drawArrays(d.LINES,0,d.lineBuffer.vertexPositionBuffer.numItems):0==this.bondOrder?d.drawElements(d.TRIANGLES,d.sphereBuffer.vertexIndexBuffer.numItems,d.UNSIGNED_SHORT,
0):d.drawElements(d.TRIANGLES,d.pillBuffer.vertexIndexBuffer.numItems,d.UNSIGNED_SHORT,0),k.translate(z,[0,g*(1+m),0]),k.scale(z,[1,1/B,1]))}}}else{if(a.bonds_showBondOrders_3D){switch(this.bondOrder){case 1.5:p=[-a.bonds_cylinderDiameter_3D];break;case 2:p=[-a.bonds_cylinderDiameter_3D,a.bonds_cylinderDiameter_3D];break;case 3:p=[-1.2*a.bonds_cylinderDiameter_3D,0,1.2*a.bonds_cylinderDiameter_3D]}1<this.bondOrder&&(A=[0,0,1],g=k.inverse(d.rotationMatrix,[]),k.multiplyVec3(g,A),A=b.cross(w,A,[]),
b.normalize(A))}else switch(this.bondOrder){case 0:f*=.25;break;case .5:case 1.5:f*=.5}u&&(h/=2);h=[f,h,f];for(let g=0,l=p.length;g<l;g++)w=k.set(x,[]),0!==p[g]&&k.translate(w,b.scale(A,p[g],[])),0!==n&&k.rotate(w,n,r),k.scale(w,h),m&&d.material.setDiffuseColor(d,m),d.shader.setMatrixUniforms(d,w),a.bonds_renderAsLines_3D?d.drawArrays(d.LINES,0,d.lineBuffer.vertexPositionBuffer.numItems):d.drawArrays(d.TRIANGLE_STRIP,0,d.cylinderBuffer.vertexPositionBuffer.numItems),u&&(k.set(u,w),0!==p[g]&&k.translate(w,
b.scale(A,p[g],[])),k.rotate(w,n+e.PI,r),k.scale(w,h),c&&d.material.setDiffuseColor(d,c),d.shader.setMatrixUniforms(d,w),a.bonds_renderAsLines_3D?d.drawArrays(d.LINES,0,d.lineBuffer.vertexPositionBuffer.numItems):d.drawArrays(d.TRIANGLE_STRIP,0,d.cylinderBuffer.vertexPositionBuffer.numItems))}}};f.renderHighlight=function(d,a){if(this.isSelected||this.isHover){this.styles&&(a=this.styles);this.styles&&(a=this.styles);let l=this.a1.distance3D(this.a2);if(0!==l){var g=a.bonds_cylinderDiameter_3D/1.2,
h=k.translate(k.identity(),[this.a1.x,this.a1.y,this.a1.z]),f=[this.a2.x-this.a1.x,this.a2.y-this.a1.y,this.a2.z-this.a1.z],m=[0,1,0],x=0;this.a1.x===this.a2.x&&this.a1.z===this.a2.z?(f=[0,0,1],this.a2.y<this.a1.y&&(x=e.PI)):(x=q.vec3AngleFrom(m,f),f=b.cross(m,f,[]));g=[g,l,g];0!==x&&k.rotate(h,x,f);k.scale(h,g);d.shader.setMatrixUniforms(d,h);d.material.setDiffuseColor(d,this.isHover?a.colorHover:a.colorSelect);d.drawArrays(d.TRIANGLE_STRIP,0,d.cylinderBuffer.vertexPositionBuffer.numItems)}}};f.renderPicker=
function(d,a){this.styles&&(a=this.styles);var g=this.a1.distance3D(this.a2);if(0!==g){var h=a.bonds_cylinderDiameter_3D/2,f=k.translate(k.identity(),[this.a1.x,this.a1.y,this.a1.z]),m=[this.a2.x-this.a1.x,this.a2.y-this.a1.y,this.a2.z-this.a1.z],x=[0,1,0],u=0;this.a1.x===this.a2.x&&this.a1.z===this.a2.z?(x=[0,0,1],this.a2.y<this.a1.y&&(u=e.PI)):(u=q.vec3AngleFrom(x,m),x=b.cross(x,m,[]));var w=[0];if(a.bonds_showBondOrders_3D)if(a.bonds_renderAsLines_3D){switch(this.bondOrder){case 1.5:case 2:w=[-a.bonds_cylinderDiameter_3D,
a.bonds_cylinderDiameter_3D];break;case 3:w=[-1.2*a.bonds_cylinderDiameter_3D,0,1.2*a.bonds_cylinderDiameter_3D]}if(1<this.bondOrder){var r=[0,0,1];let a=k.inverse(d.rotationMatrix,[]);k.multiplyVec3(a,r);r=b.cross(m,r,[]);b.normalize(r)}}else switch(this.bondOrder){case 1.5:case 2:h*=3;break;case 3:h*=3.4}else switch(this.bondOrder){case 0:h*=.25;break;case .5:case 1.5:h*=.5}g=[h,g,h];for(let e=0,c=w.length;e<c;e++)h=k.set(f,[]),0!==w[e]&&k.translate(h,b.scale(r,w[e],[])),0!==u&&k.rotate(h,u,x),
k.scale(h,g),d.shader.setMatrixUniforms(d,h),a.bonds_renderAsLines_3D?d.drawArrays(d.LINES,0,d.lineBuffer.vertexPositionBuffer.numItems):d.drawArrays(d.TRIANGLE_STRIP,0,d.cylinderBuffer.vertexPositionBuffer.numItems)}}})(ChemDoodle.ELEMENT,ChemDoodle.extensions,ChemDoodle.structures,ChemDoodle.math,Math,ChemDoodle.lib.mat4,ChemDoodle.lib.vec3);
(function(f,q,n){f.Ring=function(){this.atoms=[];this.bonds=[]};let r=f.Ring.prototype;r.center=n;r.setupBonds=function(){for(let e=0,f=this.bonds.length;e<f;e++)this.bonds[e].ring=this;this.center=this.getCenter()};r.getCenter=function(){let e=Infinity,k=Infinity,b=-Infinity,d=-Infinity;for(let h=0,a=this.atoms.length;h<a;h++)e=q.min(this.atoms[h].x,e),k=q.min(this.atoms[h].y,k),b=q.max(this.atoms[h].x,b),d=q.max(this.atoms[h].y,d);return new f.Point((b+e)/2,(d+k)/2)}})(ChemDoodle.structures,Math);
(function(f,q,n,r,e,k){n.Molecule=function(){this.atoms=[];this.bonds=[];this.rings=[]};let b=n.Molecule.prototype;b.findRings=!0;b.draw=function(b,h){this.styles&&(h=this.styles);if(h.atoms_display&&!h.atoms_circles_2D)for(let a=0,d=this.atoms.length;a<d;a++)this.atoms[a].draw(b,h);if(h.bonds_display)for(let a=0,d=this.bonds.length;a<d;a++)this.bonds[a].draw(b,h);if(h.atoms_display)for(let a=0,d=this.atoms.length;a<d;a++){let d=this.atoms[a];h.atoms_circles_2D&&d.draw(b,h);d.query&&d.query.draw(b,
h,d)}};b.render=function(b,h){this.styles&&(h=this.styles);var a=0<this.atoms.length&&this.atoms[0].hetatm!==k;if(a){if(h.macro_displayBonds){0<this.bonds.length&&(h.bonds_renderAsLines_3D&&!this.residueSpecs||this.residueSpecs&&this.residueSpecs.bonds_renderAsLines_3D?(b.lineWidth(this.residueSpecs?this.residueSpecs.bonds_width_2D:h.bonds_width_2D),b.lineBuffer.bindBuffers(b)):b.cylinderBuffer.bindBuffers(b),b.material.setTempColors(b,h.bonds_materialAmbientColor_3D,k,h.bonds_materialSpecularColor_3D,
h.bonds_materialShininess_3D));for(let a=0,g=this.bonds.length;a<g;a++){var d=this.bonds[a];!d.a1.hetatm&&(-1===h.macro_atomToLigandDistance||d.a1.closestDistance!==k&&h.macro_atomToLigandDistance>=d.a1.closestDistance&&h.macro_atomToLigandDistance>=d.a2.closestDistance)&&d.render(b,this.residueSpecs?this.residueSpecs:h)}}if(h.macro_displayAtoms){0<this.atoms.length&&(b.sphereBuffer.bindBuffers(b),b.material.setTempColors(b,h.atoms_materialAmbientColor_3D,k,h.atoms_materialSpecularColor_3D,h.atoms_materialShininess_3D));
for(let a=0,g=this.atoms.length;a<g;a++)d=this.atoms[a],!d.hetatm&&(-1===h.macro_atomToLigandDistance||d.closestDistance!==k&&h.macro_atomToLigandDistance>=d.closestDistance)&&d.render(b,this.residueSpecs?this.residueSpecs:h)}}if(h.bonds_display){d=[];var e=[];0<this.bonds.length&&(h.bonds_renderAsLines_3D?(b.lineWidth(h.bonds_width_2D),b.lineBuffer.bindBuffers(b)):b.cylinderBuffer.bindBuffers(b),b.material.setTempColors(b,h.bonds_materialAmbientColor_3D,k,h.bonds_materialSpecularColor_3D,h.bonds_materialShininess_3D));
for(let g=0,f=this.bonds.length;g<f;g++){let f=this.bonds[g];if(!a||f.a1.hetatm)h.bonds_showBondOrders_3D?0==f.bondOrder?e.push(f):.5==f.bondOrder?d.push(f):(1.5==f.bondOrder&&d.push(f),f.render(b,h)):f.render(b,h)}if(0<d.length){h.bonds_renderAsLines_3D||b.pillBuffer.bindBuffers(b);for(let a=0,g=d.length;a<g;a++)d[a].render(b,h,!0)}if(0<e.length){h.bonds_renderAsLines_3D||b.sphereBuffer.bindBuffers(b);for(let a=0,d=e.length;a<d;a++)e[a].render(b,h,!0)}}if(h.atoms_display){for(let a=0,b=this.atoms.length;a<
b;a++)d=this.atoms[a],d.bondNumber=0,d.renderAsStar=!1;for(let a=0,b=this.bonds.length;a<b;a++)d=this.bonds[a],d.a1.bondNumber++,d.a2.bondNumber++;0<this.atoms.length&&(b.sphereBuffer.bindBuffers(b),b.material.setTempColors(b,h.atoms_materialAmbientColor_3D,k,h.atoms_materialSpecularColor_3D,h.atoms_materialShininess_3D));d=[];for(let g=0,f=this.atoms.length;g<f;g++)if(e=this.atoms[g],!a||e.hetatm&&(h.macro_showWater||!e.isWater))h.atoms_nonBondedAsStars_3D&&0===e.bondNumber?(e.renderAsStar=!0,d.push(e)):
e.render(b,h);if(0<d.length){b.starBuffer.bindBuffers(b);for(let a=0,g=d.length;a<g;a++)d[a].render(b,h)}}if(this.chains){b.shader.setMatrixUniforms(b);if(h.proteins_displayRibbon){b.material.setTempColors(b,h.proteins_materialAmbientColor_3D,k,h.proteins_materialSpecularColor_3D,h.proteins_materialShininess_3D);a=h.proteins_ribbonCartoonize?this.cartoons:this.ribbons;for(let g=0,f=a.length;g<f;g++)if(d=a[g],"none"!==h.proteins_residueColor){d.front.bindBuffers(b);e="rainbow"===h.proteins_residueColor;
for(let a=0,g=d.front.segments.length;a<g;a++)e&&b.material.setDiffuseColor(b,q.rainbowAt(a,g,h.macro_rainbowColors)),d.front.segments[a].render(b,h);d.back.bindBuffers(b);for(let a=0,g=d.back.segments.length;a<g;a++)e&&b.material.setDiffuseColor(b,q.rainbowAt(a,g,h.macro_rainbowColors)),d.back.segments[a].render(b,h)}else d.front.render(b,h),d.back.render(b,h)}if(h.proteins_displayPipePlank)for(let a=0,d=this.pipePlanks.length;a<d;a++)this.pipePlanks[a].render(b,h);if(h.proteins_displayBackbone){if(!this.alphaCarbonTrace){this.alphaCarbonTrace=
{nodes:[],edges:[]};for(let b=0,g=this.chains.length;b<g;b++)if(a=this.chains[b],!(2<a.length&&r[a[2].name]&&"#BEA06E"===r[a[2].name].aminoColor)&&0<a.length)for(let b=0,g=a.length-2;b<g;b++)d=a[b].cp1,d.chainColor=a.chainColor,this.alphaCarbonTrace.nodes.push(d),d=new n.Bond(a[b].cp1,a[b+1].cp1),d.residueName=a[b].name,d.chainColor=a.chainColor,this.alphaCarbonTrace.edges.push(d),b===a.length-3&&(d=a[b+1].cp1,d.chainColor=a.chainColor,this.alphaCarbonTrace.nodes.push(d))}if(0<this.alphaCarbonTrace.nodes.length){a=
new n.Styles;a.atoms_display=!0;a.bonds_display=!0;a.atoms_sphereDiameter_3D=h.proteins_backboneThickness;a.bonds_cylinderDiameter_3D=h.proteins_backboneThickness;a.bonds_splitColor=!1;a.atoms_color=h.proteins_backboneColor;a.bonds_color=h.proteins_backboneColor;a.atoms_useVDWDiameters_3D=!1;b.material.setTempColors(b,h.proteins_materialAmbientColor_3D,k,h.proteins_materialSpecularColor_3D,h.proteins_materialShininess_3D);b.material.setDiffuseColor(b,h.proteins_backboneColor);for(let g=0,e=this.alphaCarbonTrace.nodes.length;g<
e;g++)d=this.alphaCarbonTrace.nodes[g],h.macro_colorByChain&&(a.atoms_color=d.chainColor),b.sphereBuffer.bindBuffers(b),d.render(b,a);for(let g=0,l=this.alphaCarbonTrace.edges.length;g<l;g++){d=this.alphaCarbonTrace.edges[g];var f;e=r[d.residueName]?r[d.residueName]:r["*"];h.macro_colorByChain?f=d.chainColor:"shapely"===h.proteins_residueColor?f=e.shapelyColor:"amino"===h.proteins_residueColor?f=e.aminoColor:"polarity"===h.proteins_residueColor?f=e.polar?"#C10000":"#FFFFFF":"acidity"===h.proteins_residueColor?
f=1===e.acidity?"#0000FF":-1===e.acidity?"#FF0000":e.polar?"#FFFFFF":"#773300":"rainbow"===h.proteins_residueColor&&(f=q.rainbowAt(g,l,h.macro_rainbowColors));f&&(a.bonds_color=f);b.cylinderBuffer.bindBuffers(b);d.render(b,a)}}}if(h.nucleics_display){b.material.setTempColors(b,h.nucleics_materialAmbientColor_3D,k,h.nucleics_materialSpecularColor_3D,h.nucleics_materialShininess_3D);for(let a=0,d=this.tubes.length;a<d;a++)b.shader.setMatrixUniforms(b),this.tubes[a].render(b,h)}}if(h.atoms_display){f=
!1;for(let b=0,d=this.atoms.length;b<d;b++)if(a=this.atoms[b],a.isHover||a.isSelected){f=!0;break}if(!f)for(let b=0,d=this.bonds.length;b<d;b++)if(a=this.bonds[b],a.isHover||a.isSelected){f=!0;break}if(f){b.sphereBuffer.bindBuffers(b);b.blendFunc(b.SRC_ALPHA,b.ONE);b.material.setTempColors(b,h.atoms_materialAmbientColor_3D,k,"#000000",0);b.enable(b.BLEND);b.depthMask(!1);b.material.setAlpha(b,.4);b.sphereBuffer.bindBuffers(b);for(let a=0,d=this.atoms.length;a<d;a++)f=this.atoms[a],(f.isHover||f.isSelected)&&
f.renderHighlight(b,h);b.cylinderBuffer.bindBuffers(b);for(let a=0,d=this.bonds.length;a<d;a++)f=this.bonds[a],(f.isHover||f.isSelected)&&f.renderHighlight(b,h);b.depthMask(!0);b.disable(b.BLEND);b.blendFuncSeparate(b.SRC_ALPHA,b.ONE_MINUS_SRC_ALPHA,b.ONE,b.ONE_MINUS_SRC_ALPHA)}}};b.renderPickFrame=function(b,h,a,g,e){this.styles&&(h=this.styles);var d=0<this.atoms.length&&this.atoms[0].hetatm!==k;if(e&&h.bonds_display){0<this.bonds.length&&(h.bonds_renderAsLines_3D?(b.lineWidth(h.bonds_width_2D),
b.lineBuffer.bindBuffers(b)):b.cylinderBuffer.bindBuffers(b));for(let g=0,f=this.bonds.length;g<f;g++)if(e=this.bonds[g],!d||e.a1.hetatm)b.material.setDiffuseColor(b,q.idx2color(a.length)),e.renderPicker(b,h),a.push(e)}if(g&&h.atoms_display){for(let a=0,b=this.atoms.length;a<b;a++)g=this.atoms[a],g.bondNumber=0,g.renderAsStar=!1;for(let a=0,b=this.bonds.length;a<b;a++)g=this.bonds[a],g.a1.bondNumber++,g.a2.bondNumber++;0<this.atoms.length&&b.sphereBuffer.bindBuffers(b);g=[];for(let f=0,l=this.atoms.length;f<
l;f++)if(e=this.atoms[f],!d||e.hetatm&&(h.macro_showWater||!e.isWater))h.atoms_nonBondedAsStars_3D&&0===e.bondNumber?(e.renderAsStar=!0,g.push(e)):(b.material.setDiffuseColor(b,q.idx2color(a.length)),e.render(b,h,!0),a.push(e));if(0<g.length){b.starBuffer.bindBuffers(b);for(let e=0,f=g.length;e<f;e++)d=g[e],b.material.setDiffuseColor(b,q.idx2color(a.length)),d.render(b,h,!0),a.push(d)}}};b.getCenter3D=function(){if(1===this.atoms.length)return new n.Atom("C",this.atoms[0].x,this.atoms[0].y,this.atoms[0].z);
let b=Infinity,h=Infinity,a=Infinity,g=-Infinity,f=-Infinity,k=-Infinity;if(this.chains)for(let d=0,l=this.chains.length;d<l;d++){let l=this.chains[d];for(let d=0,m=l.length;d<m;d++){let m=l[d];b=e.min(m.cp1.x,m.cp2.x,b);h=e.min(m.cp1.y,m.cp2.y,h);a=e.min(m.cp1.z,m.cp2.z,a);g=e.max(m.cp1.x,m.cp2.x,g);f=e.max(m.cp1.y,m.cp2.y,f);k=e.max(m.cp1.z,m.cp2.z,k)}}for(let d=0,l=this.atoms.length;d<l;d++)b=e.min(this.atoms[d].x,b),h=e.min(this.atoms[d].y,h),a=e.min(this.atoms[d].z,a),g=e.max(this.atoms[d].x,
g),f=e.max(this.atoms[d].y,f),k=e.max(this.atoms[d].z,k);return new n.Atom("C",(g+b)/2,(f+h)/2,(k+a)/2)};b.getCenter=function(){if(1===this.atoms.length)return new n.Point(this.atoms[0].x,this.atoms[0].y);let b=Infinity,h=Infinity,a=-Infinity,g=-Infinity;for(let d=0,f=this.atoms.length;d<f;d++)b=e.min(this.atoms[d].x,b),h=e.min(this.atoms[d].y,h),a=e.max(this.atoms[d].x,a),g=e.max(this.atoms[d].y,g);return new n.Point((a+b)/2,(g+h)/2)};b.getDimension=function(){if(1===this.atoms.length)return new n.Point(0,
0);let b=Infinity,h=Infinity,a=-Infinity,g=-Infinity;if(this.chains){for(let d=0,f=this.chains.length;d<f;d++){let f=this.chains[d];for(let d=0,l=f.length;d<l;d++){let l=f[d];b=e.min(l.cp1.x,l.cp2.x,b);h=e.min(l.cp1.y,l.cp2.y,h);a=e.max(l.cp1.x,l.cp2.x,a);g=e.max(l.cp1.y,l.cp2.y,g)}}b-=30;h-=30;a+=30;g+=30}for(let d=0,f=this.atoms.length;d<f;d++)b=e.min(this.atoms[d].x,b),h=e.min(this.atoms[d].y,h),a=e.max(this.atoms[d].x,a),g=e.max(this.atoms[d].y,g);return new n.Point(a-b,g-h)};b.check=function(b){if(b&&
this.doChecks){if(this.findRings)if(this.bonds.length-this.atoms.length!==this.fjNumCache){this.rings=(new f.informatics.SSSRFinder(this)).rings;for(let a=0,b=this.bonds.length;a<b;a++)this.bonds[a].ring=k;for(let a=0,b=this.rings.length;a<b;a++)this.rings[a].setupBonds()}else for(let a=0,b=this.rings.length;a<b;a++){var d=this.rings[a];d.center=d.getCenter()}for(let a=0,b=this.atoms.length;a<b;a++)if(this.atoms[a].isLone=!1,"C"===this.atoms[a].label){d=0;for(let b=0,g=this.bonds.length;b<g;b++)this.bonds[b].a1!==
this.atoms[a]&&this.bonds[b].a2!==this.atoms[a]||d++;0===d&&(this.atoms[a].isLone=!0)}d=!1;for(let a=0,b=this.atoms.length;a<b;a++)0!==this.atoms[a].z&&(d=!0);d&&(this.sortAtomsByZ(),this.sortBondsByZ());this.setupMetaData();this.atomNumCache=this.atoms.length;this.bondNumCache=this.bonds.length;this.fjNumCache=this.bonds.length-this.atoms.length}this.doChecks=!b};b.getAngles=function(b){let d=[];for(let a=0,g=this.bonds.length;a<g;a++)this.bonds[a].contains(b)&&d.push(b.angle(this.bonds[a].getNeighbor(b)));
d.sort(function(a,b){return a-b});return d};b.getCoordinationNumber=function(b){let d=0;for(let a=0,g=b.length;a<g;a++)d+=b[a].bondOrder;return d};b.getBonds=function(b){let d=[];for(let a=0,g=this.bonds.length;a<g;a++)this.bonds[a].contains(b)&&d.push(this.bonds[a]);return d};b.sortAtomsByZ=function(){for(let b=1,e=this.atoms.length;b<e;b++){let a=b;for(;0<a&&this.atoms[a].z<this.atoms[a-1].z;){let b=this.atoms[a];this.atoms[a]=this.atoms[a-1];this.atoms[a-1]=b;a--}}};b.sortBondsByZ=function(){for(let b=
1,e=this.bonds.length;b<e;b++){let a=b;for(;0<a&&this.bonds[a].a1.z+this.bonds[a].a2.z<this.bonds[a-1].a1.z+this.bonds[a-1].a2.z;){let b=this.bonds[a];this.bonds[a]=this.bonds[a-1];this.bonds[a-1]=b;a--}}};b.setupMetaData=function(){let b=this.getCenter();for(let d=0,a=this.atoms.length;d<a;d++){let a=this.atoms[d];a.bonds=this.getBonds(a);a.angles=this.getAngles(a);a.isHidden=2===a.bonds.length&&e.abs(e.abs(a.angles[1]-a.angles[0])-e.PI)<e.PI/30&&a.bonds[0].bondOrder===a.bonds[1].bondOrder;let h=
q.angleBetweenLargest(a.angles);a.angleOfLeastInterference=h.angle%(2*e.PI);a.largestAngle=h.largest;a.coordinationNumber=this.getCoordinationNumber(a.bonds);a.bondNumber=a.bonds.length;a.molCenter=b}for(let d=0,a=this.bonds.length;d<a;d++)this.bonds[d].molCenter=b};b.scaleToAverageBondLength=function(b){let d=this.getAverageBondLength();if(0!==d){b/=d;for(let a=0,d=this.atoms.length;a<d;a++)this.atoms[a].x*=b,this.atoms[a].y*=b}};b.getAverageBondLength=function(){if(0===this.bonds.length)return 0;
let b=0;for(let d=0,a=this.bonds.length;d<a;d++)b+=this.bonds[d].getLength();return b/=this.bonds.length};b.getBounds=function(){let b=new q.Bounds;for(let d=0,a=this.atoms.length;d<a;d++)b.expand(this.atoms[d].getBounds());if(this.chains){for(let d=0,a=this.chains.length;d<a;d++){let a=this.chains[d];for(let d=0,g=a.length;d<g;d++){let g=a[d];b.expand(g.cp1.x,g.cp1.y);b.expand(g.cp2.x,g.cp2.y)}}b.minX-=30;b.minY-=30;b.maxX+=30;b.maxY+=30}return b};b.getBounds3D=function(){let b=new q.Bounds;for(let d=
0,a=this.atoms.length;d<a;d++)b.expand(this.atoms[d].getBounds3D());if(this.chains)for(let d=0,a=this.chains.length;d<a;d++){let a=this.chains[d];for(let d=0,g=a.length;d<g;d++){let g=a[d];b.expand3D(g.cp1.x,g.cp1.y,g.cp1.z);b.expand3D(g.cp2.x,g.cp2.y,g.cp2.z)}}return b};b.getAtomGroup=function(b){let d=!1;for(let a=0,b=this.atoms.length;a<b;a++)this.atoms[a].visited=!1;for(let g=0,e=this.bonds.length;g<e;g++){var a=this.bonds[g];!d&&a.contains(b)&&a.ring!==k&&(d=!0)}if(!d)return k;a=[b];b.visited=
!0;let g=new n.Queue;for(g.enqueue(b);!g.isEmpty();){b=g.dequeue();for(let h=0,f=this.bonds.length;h<f;h++){var e=this.bonds[h];e.contains(b)&&d===(e.ring!==k)&&(e=e.getNeighbor(b),e.visited||(e.visited=!0,a.push(e),g.enqueue(e)))}}return a};b.getBondGroup=function(b){let d=b.ring!==k;var a=!1;for(let d=0,e=this.bonds.length;d<e;d++){var g=this.bonds[d];g===b&&(a=!0);g.visited=!1}if(!a)return k;a=[b];b.visited=!0;g=new n.Queue;for(g.enqueue(b);!g.isEmpty();){b=g.dequeue();for(let e=0,h=this.bonds.length;e<
h;e++){let h=this.bonds[e];h.visited||h.a1!==b.a1&&h.a2!==b.a1&&h.a1!==b.a2&&h.a2!==b.a2||h.ring!==k!==d||(h.visited=!0,a.push(h),g.enqueue(h))}}return a}})(ChemDoodle,ChemDoodle.math,ChemDoodle.structures,ChemDoodle.RESIDUE,Math);
(function(f,q,n,r,e){let k,b=-1;f.Residue=function(b){this.resSeq=b};e=f.Residue.prototype;e.setup=function(b,e){this.horizontalResolution=e;let a=[b.x-this.cp1.x,b.y-this.cp1.y,b.z-this.cp1.z];var d=r.cross(a,[this.cp2.x-this.cp1.x,this.cp2.y-this.cp1.y,this.cp2.z-this.cp1.z],[]);this.D=r.cross(d,a,[]);r.normalize(d);r.normalize(this.D);this.guidePointsSmall=[];this.guidePointsLarge=[];b=[(b.x+this.cp1.x)/2,(b.y+this.cp1.y)/2,(b.z+this.cp1.z)/2];this.helix&&(r.scale(d,1.5),r.add(b,d));this.guidePointsSmall[0]=
new f.Atom("",b[0]-this.D[0]/2,b[1]-this.D[1]/2,b[2]-this.D[2]/2);for(d=1;d<e;d++)this.guidePointsSmall[d]=new f.Atom("",this.guidePointsSmall[0].x+this.D[0]*d/e,this.guidePointsSmall[0].y+this.D[1]*d/e,this.guidePointsSmall[0].z+this.D[2]*d/e);r.scale(this.D,4);this.guidePointsLarge[0]=new f.Atom("",b[0]-this.D[0]/2,b[1]-this.D[1]/2,b[2]-this.D[2]/2);for(d=1;d<e;d++)this.guidePointsLarge[d]=new f.Atom("",this.guidePointsLarge[0].x+this.D[0]*d/e,this.guidePointsLarge[0].y+this.D[1]*d/e,this.guidePointsLarge[0].z+
this.D[2]*d/e)};e.getGuidePointSet=function(b){if(0===b)return this.helix||this.sheet?this.guidePointsLarge:this.guidePointsSmall;if(1===b)return this.guidePointsSmall;if(2===b)return this.guidePointsLarge};e.computeLineSegments=function(b,e,a,g,f){this.setVerticalResolution(f);this.split=a.helix!==this.helix||a.sheet!==this.sheet;this.lineSegments=this.innerCompute(0,b,e,a,!1,f);g&&(this.lineSegmentsCartoon=this.innerCompute(this.helix||this.sheet?2:1,b,e,a,!0,f))};e.innerCompute=function(b,e,a,
g,l,v){let d=[];var h=this.getGuidePointSet(b);e=e.getGuidePointSet(b);a=a.getGuidePointSet(b);b=g.getGuidePointSet(b);for(let l=0,m=h.length;l<m;l++){g=n.multiply([e[l].x,e[l].y,e[l].z,1,a[l].x,a[l].y,a[l].z,1,h[l].x,h[l].y,h[l].z,1,b[l].x,b[l].y,b[l].z,1],k,[]);let m=[];for(let a=0;a<v;a++){for(let a=3;0<a;a--)for(let b=0;4>b;b++)g[4*a+b]+=g[4*(a-1)+b];m[a]=new f.Atom("",g[12]/g[15],g[13]/g[15],g[14]/g[15])}d[l]=m}if(l&&this.arrow)for(let f=0,m=v;f<m;f++){l=1.5-1.3*f/v;h=q.floor(this.horizontalResolution/
2);e=d[h];for(let m=0,k=d.length;m<k;m++)m!==h&&(a=e[f],b=d[m][f],g=[b.x-a.x,b.y-a.y,b.z-a.z],r.scale(g,l),b.x=a.x+g[0],b.y=a.y+g[1],b.z=a.z+g[2])}return d};e.setVerticalResolution=function(d){if(d!==b){{let e=d*d,a=d*d*d;k=n.multiply([-1/6,.5,-.5,1/6,.5,-1,.5,0,-.5,0,.5,0,1/6,2/3,1/6,0],[6/a,0,0,0,6/a,2/e,0,0,1/a,1/e,1/d,0,0,0,0,1],[]);b=d}}}})(ChemDoodle.structures,Math,ChemDoodle.lib.mat4,ChemDoodle.lib.vec3);
(function(f,q,n,r,e,k){q.Spectrum=function(){this.data=[];this.metadata=[];this.dataDisplay=[];this.memory={offsetTop:0,offsetLeft:0,offsetBottom:0,flipXAxis:!1,scale:1,width:0,height:0}};r=q.Spectrum.prototype;r.title=k;r.xUnit=k;r.yUnit=k;r.continuous=!0;r.integrationSensitivity=.01;r.draw=function(b,d,h,a){this.styles&&(d=this.styles);let g=5,l=0,k=0;b.fillStyle=d.text_color;b.textAlign="center";b.textBaseline="alphabetic";b.font=f.getFontString(d.text_font_size,d.text_font_families);this.xUnit&&
(k+=d.text_font_size,b.fillText(this.xUnit,h/2,a-2));this.yUnit&&d.plots_showYAxis&&(l+=d.text_font_size,b.save(),b.translate(d.text_font_size,a/2),b.rotate(-e.PI/2),b.fillText(this.yUnit,0,0),b.restore());this.title&&(g+=d.text_font_size,b.fillText(this.title,h/2,d.text_font_size));b.lineCap="square";k+=5+d.text_font_size;d.plots_showYAxis&&(l+=5+b.measureText("1000").width);d.plots_showGrid&&(b.strokeStyle=d.plots_gridColor,b.lineWidth=d.plots_gridLineWidth,b.strokeRect(l,g,h-l,a-k-g));b.textAlign=
"center";b.textBaseline="top";for(var m=this.maxX-this.minX,r=m/100,u=.001;u<r||25<m/u;)u*=10;m=0;r=d.plots_flipXAxis?h:0;for(var w=e.round(this.minX/u)*u;w<=this.maxX;w+=u/2){var n=this.getTransformedX(w,d,h,l);if(n>l)if(b.strokeStyle="black",b.lineWidth=1,0===m%2){b.beginPath();b.moveTo(n,a-k);b.lineTo(n,a-k+2);b.stroke();let e=w.toFixed(5);for(;"0"===e.charAt(e.length-1);)e=e.substring(0,e.length-1);"."===e.charAt(e.length-1)&&(e=e.substring(0,e.length-1));let c=b.measureText(e).width;d.plots_flipXAxis&&
(c*=-1);let h=n-c/2;if(d.plots_flipXAxis?h<r:h>r)b.fillText(e,n,a-k+2),r=n+c/2;d.plots_showGrid&&(b.strokeStyle=d.plots_gridColor,b.lineWidth=d.plots_gridLineWidth,b.beginPath(),b.moveTo(n,a-k),b.lineTo(n,g),b.stroke())}else b.beginPath(),b.moveTo(n,a-k),b.lineTo(n,a-k+2),b.stroke();m++}if(d.plots_showYAxis||d.plots_showGrid)for(u=1/d.scale,b.textAlign="right",b.textBaseline="middle",m=0;10>=m;m++)if(w=u/10*m,r=g+(a-k-g)*(1-w*d.scale),d.plots_showGrid&&(b.strokeStyle=d.plots_gridColor,b.lineWidth=
d.plots_gridLineWidth,b.beginPath(),b.moveTo(l,r),b.lineTo(h,r),b.stroke()),d.plots_showYAxis){b.strokeStyle="black";b.lineWidth=1;b.beginPath();b.moveTo(l,r);b.lineTo(l-3,r);b.stroke();n=100*w;w=e.max(0,3-e.floor(n).toString().length);n=n.toFixed(w);if(0<w)for(;"0"===n.charAt(n.length-1);)n=n.substring(0,n.length-1);"."===n.charAt(n.length-1)&&(n=n.substring(0,n.length-1));b.fillText(n,l-3,r)}b.strokeStyle="black";b.lineWidth=1;b.beginPath();b.moveTo(h,a-k);b.lineTo(l,a-k);d.plots_showYAxis&&b.lineTo(l,
g);b.stroke();if(0<this.dataDisplay.length){b.textAlign="left";b.textBaseline="top";u=0;for(let a=0,c=this.dataDisplay.length;a<c;a++)if(this.dataDisplay[a].value)b.fillText([this.dataDisplay[a].display,": ",this.dataDisplay[a].value].join(""),l+10,g+10+u*(d.text_font_size+5)),u++;else if(this.dataDisplay[a].tag)for(let c=0,e=this.metadata.length;c<e;c++)if(this.metadata[c].startsWith(this.dataDisplay[a].tag)){m=this.metadata[c];this.dataDisplay[a].display&&(m=this.metadata[c].indexOf("\x3d"),m=[this.dataDisplay[a].display,
": ",-1<m?this.metadata[c].substring(m+2):this.metadata[c]].join(""));b.fillText(m,l+10,g+10+u*(d.text_font_size+5));u++;break}}this.drawPlot(b,d,h,a,g,l,k);this.memory.offsetTop=g;this.memory.offsetLeft=l;this.memory.offsetBottom=k;this.memory.flipXAxis=d.plots_flipXAxis;this.memory.scale=d.scale;this.memory.width=h;this.memory.height=a};r.drawPlot=function(b,d,h,a,g,f,v){this.styles&&(d=this.styles);b.strokeStyle=d.plots_color;b.lineWidth=d.plots_width;let l=[];b.save();b.rect(f,g,h-f,a-v-g);b.clip();
b.beginPath();if(this.continuous){var r=!1,u=0,n=!1;for(let m=0,w=this.data.length;m<w;m++){let c=this.getTransformedX(this.data[m].x,d,h,f),p;m<w&&!r&&this.data[m+1]&&(p=this.getTransformedX(this.data[m+1].x,d,h,f));if(c>=f&&c<h||p!==k&&p>=f&&p<h){let h=this.getTransformedY(this.data[m].y,d,a,v,g);d.plots_showIntegration&&e.abs(this.data[m].y)>this.integrationSensitivity&&l.push(new q.Point(this.data[m].x,this.data[m].y));r||(b.moveTo(c,h),r=!0);b.lineTo(c,h);u++;0===u%1E3&&(b.stroke(),b.beginPath(),
b.moveTo(c,h));if(n)break}else r&&(n=!0)}}else for(let e=0,l=this.data.length;e<l;e++)r=this.getTransformedX(this.data[e].x,d,h,f),r>=f&&r<h&&(b.moveTo(r,a-v),b.lineTo(r,this.getTransformedY(this.data[e].y,d,a,v,g)));b.stroke();if(d.plots_showIntegration&&1<l.length){b.strokeStyle=d.plots_integrationColor;b.lineWidth=d.plots_integrationLineWidth;b.beginPath();r=l[1].x>l[0].x;if(this.flipXAxis&&!r||!this.flipXAxis&&r){for(r=l.length-2;0<=r;r--)l[r].y+=l[r+1].y;r=l[0].y}else{for(let a=1,b=l.length;a<
b;a++)l[a].y+=l[a-1].y;r=l[l.length-1].y}for(let e=0,m=l.length;e<m;e++)u=this.getTransformedX(l[e].x,d,h,f),n=this.getTransformedY(l[e].y/d.scale/r,d,a,v,g),0===e?b.moveTo(u,n):b.lineTo(u,n);b.stroke()}b.restore()};r.getTransformedY=function(b,d,e,a,g){return g+(e-a-g)*(1-b*d.scale)};r.getInverseTransformedY=function(b){return(1-(b-this.memory.offsetTop)/(this.memory.height-this.memory.offsetBottom-this.memory.offsetTop))/this.memory.scale*100};r.getTransformedX=function(b,d,e,a){b=a+(b-this.minX)/
(this.maxX-this.minX)*(e-a);d.plots_flipXAxis&&(b=e+a-b);return b};r.getInverseTransformedX=function(b){this.memory.flipXAxis&&(b=this.memory.width+this.memory.offsetLeft-b);return(b-this.memory.offsetLeft)*(this.maxX-this.minX)/(this.memory.width-this.memory.offsetLeft)+this.minX};r.setup=function(){let b=Number.MAX_VALUE,d=Number.MIN_VALUE,h=Number.MIN_VALUE;for(let a=0,g=this.data.length;a<g;a++)b=e.min(b,this.data[a].x),d=e.max(d,this.data[a].x),h=e.max(h,this.data[a].y);this.continuous?(this.minX=
b,this.maxX=d):(this.minX=b-1,this.maxX=d+1);for(let a=0,b=this.data.length;a<b;a++)this.data[a].y/=h};r.zoom=function(b,d,h,a){b=this.getInverseTransformedX(b);d=this.getInverseTransformedX(d);this.minX=e.min(b,d);this.maxX=e.max(b,d);if(a){a=Number.MIN_VALUE;for(let b=0,d=this.data.length;b<d;b++)n.isBetween(this.data[b].x,this.minX,this.maxX)&&(a=e.max(a,this.data[b].y));return 1/a}};r.translate=function(b,d){b=b/(d-this.memory.offsetLeft)*(this.maxX-this.minX)*(this.memory.flipXAxis?1:-1);this.minX+=
b;this.maxX+=b};r.alertMetadata=function(){alert(this.metadata.join("\n"))};r.getInternalCoordinates=function(b,d){return new ChemDoodle.structures.Point(this.getInverseTransformedX(b),this.getInverseTransformedY(d))};r.getClosestPlotInternalCoordinates=function(b){var d=this.getInverseTransformedX(b-1);b=this.getInverseTransformedX(b+1);if(d>b){var e=d;d=b;b=e}e=-1;let a=-Infinity,g=!1;for(let h=0,f=this.data.length;h<f;h++){let f=this.data[h];if(n.isBetween(f.x,d,b))f.y>a&&(g=!0,a=f.y,e=h);else if(g)break}if(-1===
e)return k;d=this.data[e];return new ChemDoodle.structures.Point(d.x,100*d.y)};r.getClosestPeakInternalCoordinates=function(b){var d=this.getInverseTransformedX(b);b=0;var h=Infinity;for(let g=0,f=this.data.length;g<f;g++){var a=e.abs(this.data[g].x-d);if(a<=h)h=a,b=g;else break}h=d=b;a=this.data[b].y;var g=this.data[b].y;for(let a=b+1,d=this.data.length;a<d;a++)if(this.data[a].y+.05>g)g=this.data[a].y,h=a;else break;for(g=b-1;0<=g;g--)if(this.data[g].y+.05>a)a=this.data[g].y,d=g;else break;b=this.data[d-
b>h-b?h:d];return new ChemDoodle.structures.Point(b.x,100*b.y)}})(ChemDoodle.extensions,ChemDoodle.structures,ChemDoodle.math,ChemDoodle.lib.jQuery,Math);
(function(f,q,n,r){q._Shape=function(){};q=q._Shape.prototype;q.drawDecorations=function(e,f){if(this.isHover){let b=this.getPoints();for(let d=0,h=b.length;d<h;d++){let a=b[d];this.drawAnchor(e,f,a,a===this.hoverPoint)}}};q.getBounds=function(){let e=new f.Bounds,k=this.getPoints();for(let b=0,d=k.length;b<d;b++){let d=k[b];e.expand(d.x,d.y)}return e};q.drawAnchor=function(e,f,b,d){e.save();e.translate(b.x,b.y);e.rotate(n.PI/4);e.scale(1/f.scale,1/f.scale);e.beginPath();e.moveTo(-4,-4);e.lineTo(4,
-4);e.lineTo(4,4);e.lineTo(-4,4);e.closePath();e.fillStyle=d?f.colorHover:"white";e.fill();e.beginPath();e.moveTo(-4,-2);e.lineTo(-4,-4);e.lineTo(-2,-4);e.moveTo(2,-4);e.lineTo(4,-4);e.lineTo(4,-2);e.moveTo(4,2);e.lineTo(4,4);e.lineTo(2,4);e.moveTo(-2,4);e.lineTo(-4,4);e.lineTo(-4,2);e.moveTo(-4,-2);e.strokeStyle="rgba(0,0,0,.2)";e.lineWidth=5;e.stroke();e.strokeStyle="blue";e.lineWidth=1;e.stroke();e.restore()}})(ChemDoodle.math,ChemDoodle.structures.d2,Math);
(function(f,q,n,r,e,k){r.AtomMapping=function(b,d){this.o1=b;this.o2=d;this.label="0";this.error=!1};q=r.AtomMapping.prototype=new r._Shape;q.drawDecorations=function(b,d){if(this.isHover||this.isSelected)b.strokeStyle=this.isHover?d.colorHover:d.colorSelect,b.lineWidth=1,b.beginPath(),b.moveTo(this.o1.x,this.o1.y),b.lineTo(this.o2.x,this.o2.y),b.setLineDash([2]),b.stroke(),b.setLineDash([])};q.draw=function(b,d){if(this.o1&&this.o2){this.x1=this.o1.x+14*e.cos(this.o1.angleOfLeastInterference);this.y1=
this.o1.y-14*e.sin(this.o1.angleOfLeastInterference);this.x2=this.o2.x+14*e.cos(this.o2.angleOfLeastInterference);this.y2=this.o2.y-14*e.sin(this.o2.angleOfLeastInterference);b.font=f.getFontString(d.text_font_size,d.text_font_families,d.text_font_bold,d.text_font_italic);let h=this.label,a=b.measureText(h).width;this.isLassoed&&(b.fillStyle=d.colorHover,b.fillRect(this.x1-a/2-3,this.y1-d.text_font_size/2-3,a+6,d.text_font_size+6),b.fillRect(this.x2-a/2-3,this.y2-d.text_font_size/2-3,a+6,d.text_font_size+
6));let g=this.error?d.colorError:d.shapes_color;if(this.isHover||this.isSelected)g=this.isHover?d.colorHover:d.colorSelect;b.fillStyle=g;b.fillRect(this.x1-a/2-1,this.y1-d.text_font_size/2-1,a+2,d.text_font_size+2);b.fillRect(this.x2-a/2-1,this.y2-d.text_font_size/2-1,a+2,d.text_font_size+2);b.textAlign="center";b.textBaseline="middle";b.fillStyle=d.backgroundColor;b.fillText(h,this.x1,this.y1);b.fillText(h,this.x2,this.y2)}};q.getPoints=function(){return[new n.Point(this.x1,this.y1),new n.Point(this.x2,
this.y2)]};q.isOver=function(b,d){return this.x1?b.distance({x:this.x1,y:this.y1})<d||b.distance({x:this.x2,y:this.y2})<d:!1}})(ChemDoodle.extensions,ChemDoodle.math,ChemDoodle.structures,ChemDoodle.structures.d2,Math);
(function(f,q,n,r,e,k){r.Bracket=function(b,d){this.p1=b?b:new n.Point;this.p2=d?d:new n.Point};r=r.Bracket.prototype=new r._Shape;r.charge=0;r.mult=0;r.repeat=0;r.draw=function(b,d){let h=e.min(this.p1.x,this.p2.x),a=e.max(this.p1.x,this.p2.x),g=e.min(this.p1.y,this.p2.y),l=e.max(this.p1.y,this.p2.y),k=l-g;var m=k/10;b.beginPath();b.moveTo(h+m,g);b.lineTo(h,g);b.lineTo(h,l);b.lineTo(h+m,l);b.moveTo(a-m,l);b.lineTo(a,l);b.lineTo(a,g);b.lineTo(a-m,g);this.isLassoed&&(m=b.createLinearGradient(this.p1.x,
this.p1.y,this.p2.x,this.p2.y),m.addColorStop(0,"rgba(212, 99, 0, 0)"),m.addColorStop(.5,"rgba(212, 99, 0, 0.8)"),m.addColorStop(1,"rgba(212, 99, 0, 0)"),b.lineWidth=d.shapes_lineWidth+5,b.strokeStyle=m,b.lineJoin="miter",b.lineCap="square",b.stroke());b.strokeStyle=d.shapes_color;b.lineWidth=d.shapes_lineWidth;b.lineJoin="miter";b.lineCap="butt";b.stroke();0!==this.charge&&(b.fillStyle=d.text_color,b.textAlign="left",b.textBaseline="alphabetic",b.font=f.getFontString(d.text_font_size,d.text_font_families),
m=this.charge.toFixed(0),m="1"===m?"+":"-1"===m?"\u2013":m.startsWith("-")?m.substring(1)+"\u2013":m+"+",b.fillText(m,a+5,g+5));0!==this.mult&&(b.fillStyle=d.text_color,b.textAlign="right",b.textBaseline="middle",b.font=f.getFontString(d.text_font_size,d.text_font_families),b.fillText(this.mult.toFixed(0),h-5,g+k/2));0!==this.repeat&&(b.fillStyle=d.text_color,b.textAlign="left",b.textBaseline="top",b.font=f.getFontString(d.text_font_size,d.text_font_families),d=this.repeat.toFixed(0),b.fillText(d,
a+5,l-5))};r.getPoints=function(){return[this.p1,this.p2]};r.isOver=function(b,d){return q.isBetween(b.x,this.p1.x,this.p2.x)&&q.isBetween(b.y,this.p1.y,this.p2.y)}})(ChemDoodle.extensions,ChemDoodle.math,ChemDoodle.structures,ChemDoodle.structures.d2,Math);
(function(f,q,n,r,e,k,b){e.DynamicBracket=function(b,a){this.b1=b;this.b2=a;this.n1=1;this.n2=4;this.contents=[];this.ps=[]};q=e.DynamicBracket.prototype=new e._Shape;q.drawDecorations=function(b,a){if(this.isHover)for(let d=0,e=this.contents.length;d<e;d++){a=this.contents[d];let g=b.createRadialGradient(a.x-1,a.y-1,0,a.x,a.y,7);g.addColorStop(0,"rgba(212, 99, 0, 0)");g.addColorStop(.7,"rgba(212, 99, 0, 0.8)");b.fillStyle=g;b.beginPath();b.arc(a.x,a.y,5,0,2*k.PI,!1);b.fill()}};let d=function(b,a,
d,e,f){a=[];var g=0<f.length?-1===f.indexOf(d.a1)?d.a2:d.a1:d.a1.distance(e.getCenter())<d.a2.distance(e.getCenter())?d.a1:d.a2;e=g.angle(d.getNeighbor(g));var h=e+k.PI/2;d=d.getLength()/(1<f.length?4:2);f=g.x+d*k.cos(e);g=g.y-d*k.sin(e);var l=10*k.cos(h),v=10*k.sin(h);h=f+l;d=g-v;f-=l;g+=v;v=-4*k.cos(e);var n=-4*k.sin(e);e=h+v;l=d-n;v=f+v;n=g-n;b.beginPath();b.moveTo(e,l);b.lineTo(h,d);b.lineTo(f,g);b.lineTo(v,n);b.stroke();a.push(new r.Point(h,d));a.push(new r.Point(f,g));return a};q.draw=function(b,
a){if(this.b1&&this.b2){var g=this.error?a.colorError:a.shapes_color;if(this.isHover||this.isSelected)g=this.isHover?a.colorHover:a.colorSelect;b.strokeStyle=g;b.fillStyle=b.strokeStyle;b.lineWidth=a.shapes_lineWidth;b.lineJoin="miter";b.lineCap="butt";g=d(b,a,this.b1,this.b2,this.contents);let e=d(b,a,this.b2,this.b1,this.contents);this.ps=g.concat(e);this.b1.getCenter().x>this.b2.getCenter().x?this.textPos=this.ps[0].x>this.ps[1].x+5?this.ps[0]:this.ps[1]:this.textPos=this.ps[2].x>this.ps[3].x+
5?this.ps[2]:this.ps[3];!this.error&&0<this.contents.length&&(b.font=f.getFontString(a.text_font_size,a.text_font_families,a.text_font_bold,a.text_font_italic),b.fillStyle=this.isHover?a.colorHover:a.text_color,b.textAlign="left",b.textBaseline="bottom",b.fillText(this.n1+"-"+this.n2,this.textPos.x+2,this.textPos.y+2))}};q.getPoints=function(){return this.ps};q.isOver=function(b,a){return!1};q.setContents=function(d){this.contents=[];let a=d.getMoleculeByAtom(this.b1.a1);d=d.getMoleculeByAtom(this.b2.a1);
if(a&&a===d){var g=d=0;for(let b=0,f=a.rings.length;b<f;b++){var e=a.rings[b];for(let a=0,b=e.bonds.length;a<b;a++){var h=e.bonds[a];h===this.b1?d++:h===this.b2&&g++}}d=1===d&&1===g&&this.b1.ring===this.b2.ring;this.contents.flippable=d;if(this.b1.ring===b&&this.b2.ring===b||d)for(let b=0,f=a.atoms.length;b<f;b++){h=e=g=!1;for(let b=0,d=a.bonds.length;b<d;b++)a.bonds[b].visited=!1;let f=new r.Queue,l=a.atoms[b];for(f.enqueue(l);!(f.isEmpty()||g&&e);){let b=f.dequeue();d&&(!this.flip&&b===this.b1.a1||
this.flip&&b===this.b1.a2)&&(h=!0);for(let d=0,c=a.bonds.length;d<c;d++){let c=a.bonds[d];if(c.a1===b||c.a2===b)c===this.b1?g=!0:c===this.b2?e=!0:c.visited||(c.visited=!0,f.enqueue(c.getNeighbor(b)))}}g&&e&&(!d||h)&&this.contents.push(l)}}}})(ChemDoodle.extensions,ChemDoodle.math,ChemDoodle.lib.jsBezier,ChemDoodle.structures,ChemDoodle.structures.d2,Math);
(function(f,q,n,r,e,k){r.Line=function(b,e){this.p1=b?b:new n.Point;this.p2=e?e:new n.Point};r.Line.ARROW_SYNTHETIC="synthetic";r.Line.ARROW_RETROSYNTHETIC="retrosynthetic";r.Line.ARROW_RESONANCE="resonance";r.Line.ARROW_EQUILIBRIUM="equilibrium";let b=r.Line.prototype=new r._Shape;b.arrowType=k;b.topText=k;b.bottomText=k;b.draw=function(b,h){if(this.isLassoed){var a=b.createLinearGradient(this.p1.x,this.p1.y,this.p2.x,this.p2.y);a.addColorStop(0,"rgba(212, 99, 0, 0)");a.addColorStop(.5,"rgba(212, 99, 0, 0.8)");
a.addColorStop(1,"rgba(212, 99, 0, 0)");var d=this.p1.angle(this.p2)+e.PI/2,l=e.cos(d),k=e.sin(d);d=this.p1.x-2.5*l;var m=this.p1.y+2.5*k,n=this.p1.x+2.5*l,u=this.p1.y-2.5*k,w=this.p2.x+2.5*l,q=this.p2.y-2.5*k;l=this.p2.x-2.5*l;k=this.p2.y+2.5*k;b.fillStyle=a;b.beginPath();b.moveTo(d,m);b.lineTo(n,u);b.lineTo(w,q);b.lineTo(l,k);b.closePath();b.fill()}b.strokeStyle=h.shapes_color;b.fillStyle=h.shapes_color;b.lineWidth=h.shapes_lineWidth;b.lineJoin="miter";b.lineCap="butt";if(this.p1.x!==this.p2.x||
this.p1.y!==this.p2.y){if(this.arrowType===r.Line.ARROW_RETROSYNTHETIC){d=2*e.sqrt(2);a=h.shapes_arrowLength_2D/d;n=this.p1.angle(this.p2);u=n+e.PI/2;d=h.shapes_arrowLength_2D/d;m=e.cos(n);n=e.sin(n);let g=e.cos(u),f=e.sin(u);u=this.p1.x-g*a;w=this.p1.y+f*a;q=this.p1.x+g*a;l=this.p1.y-f*a;k=this.p2.x+g*a-m*d;var y=this.p2.y-f*a+n*d,c=this.p2.x-g*a-m*d,p=this.p2.y+f*a+n*d,A=this.p2.x+g*a*2-m*d*2;let v=this.p2.y-f*a*2+n*d*2;m=this.p2.x-g*a*2-m*d*2;a=this.p2.y+f*a*2+n*d*2;b.beginPath();b.moveTo(q,l);
b.lineTo(k,y);b.moveTo(A,v);b.lineTo(this.p2.x,this.p2.y);b.lineTo(m,a);b.moveTo(c,p);b.lineTo(u,w)}else this.arrowType===r.Line.ARROW_EQUILIBRIUM?(a=2*e.sqrt(2),y=h.shapes_arrowLength_2D/a/2,m=this.p1.angle(this.p2),u=m+e.PI/2,a=2*h.shapes_arrowLength_2D/e.sqrt(3),d=e.cos(m),m=e.sin(m),n=e.cos(u),u=e.sin(u),w=this.p1.x-n*y,q=this.p1.y+u*y,c=this.p1.x+n*y,p=this.p1.y-u*y,l=this.p2.x+n*y,k=this.p2.y-u*y,A=this.p2.x-n*y,y=this.p2.y+u*y,b.beginPath(),b.moveTo(c,p),b.lineTo(l,k),b.moveTo(A,y),b.lineTo(w,
q),b.stroke(),y=l-d*a*.8,c=k+m*a*.8,p=l+n*h.shapes_arrowLength_2D/3-d*a,A=k-u*h.shapes_arrowLength_2D/3+m*a,b.beginPath(),b.moveTo(l,k),b.lineTo(p,A),b.lineTo(y,c),b.closePath(),b.fill(),b.stroke(),y=w+d*a*.8,c=q-m*a*.8,p=w-n*h.shapes_arrowLength_2D/3+d*a,A=q+u*h.shapes_arrowLength_2D/3-m*a,b.beginPath(),b.moveTo(w,q),b.lineTo(p,A),b.lineTo(y,c),b.closePath(),b.fill()):this.arrowType===r.Line.ARROW_SYNTHETIC?(m=this.p1.angle(this.p2),n=m+e.PI/2,a=2*h.shapes_arrowLength_2D/e.sqrt(3),d=e.cos(m),m=e.sin(m),
l=e.cos(n),k=e.sin(n),b.beginPath(),b.moveTo(this.p1.x,this.p1.y),b.lineTo(this.p2.x-d*a/2,this.p2.y+m*a/2),b.stroke(),n=this.p2.x-d*a*.8,u=this.p2.y+m*a*.8,w=this.p2.x+l*h.shapes_arrowLength_2D/3-d*a,q=this.p2.y-k*h.shapes_arrowLength_2D/3+m*a,d=this.p2.x-l*h.shapes_arrowLength_2D/3-d*a,a=this.p2.y+k*h.shapes_arrowLength_2D/3+m*a,b.beginPath(),b.moveTo(this.p2.x,this.p2.y),b.lineTo(d,a),b.lineTo(n,u),b.lineTo(w,q),b.closePath(),b.fill()):this.arrowType===r.Line.ARROW_RESONANCE?(m=this.p1.angle(this.p2),
u=m+e.PI/2,a=2*h.shapes_arrowLength_2D/e.sqrt(3),d=e.cos(m),m=e.sin(m),n=e.cos(u),u=e.sin(u),b.beginPath(),b.moveTo(this.p1.x+d*a/2,this.p1.y-m*a/2),b.lineTo(this.p2.x-d*a/2,this.p2.y+m*a/2),b.stroke(),w=this.p2.x-d*a*.8,q=this.p2.y+m*a*.8,l=this.p2.x+n*h.shapes_arrowLength_2D/3-d*a,k=this.p2.y-u*h.shapes_arrowLength_2D/3+m*a,y=this.p2.x-n*h.shapes_arrowLength_2D/3-d*a,c=this.p2.y+u*h.shapes_arrowLength_2D/3+m*a,b.beginPath(),b.moveTo(this.p2.x,this.p2.y),b.lineTo(y,c),b.lineTo(w,q),b.lineTo(l,k),
b.closePath(),b.fill(),b.stroke(),w=this.p1.x+d*a*.8,q=this.p1.y-m*a*.8,l=this.p1.x-n*h.shapes_arrowLength_2D/3+d*a,k=this.p1.y+u*h.shapes_arrowLength_2D/3-m*a,y=this.p1.x+n*h.shapes_arrowLength_2D/3+d*a,c=this.p1.y-u*h.shapes_arrowLength_2D/3-m*a,b.beginPath(),b.moveTo(this.p1.x,this.p1.y),b.lineTo(y,c),b.lineTo(w,q),b.lineTo(l,k),b.closePath(),b.fill()):(b.beginPath(),b.moveTo(this.p1.x,this.p1.y),b.lineTo(this.p2.x,this.p2.y));b.stroke();if(this.topText||this.bottomText)b.font=f.getFontString(h.text_font_size,
h.text_font_families,h.text_font_bold,h.text_font_italic),b.fillStyle=h.text_color;this.topText&&(b.textAlign="center",b.textBaseline="bottom",b.fillText(this.topText,(this.p1.x+this.p2.x)/2,this.p1.y-5));this.bottomText&&(b.textAlign="center",b.textBaseline="top",b.fillText(this.bottomText,(this.p1.x+this.p2.x)/2,this.p1.y+5))}};b.getPoints=function(){return[this.p1,this.p2]};b.isOver=function(b,e){b=q.distanceFromPointToLineInclusive(b,this.p1,this.p2);return-1!==b&&b<e}})(ChemDoodle.extensions,
ChemDoodle.math,ChemDoodle.structures,ChemDoodle.structures.d2,Math);
(function(f,q,n,r,e,k){let b=function(a){let b=[];if(a instanceof n.Atom)if(0===a.bondNumber)b.push(e.PI);else{if(a.angles){if(1===a.angles.length)b.push(a.angles[0]+e.PI);else{for(let d=1,g=a.angles.length;d<g;d++)b.push(a.angles[d-1]+(a.angles[d]-a.angles[d-1])/2);var d=a.angles[a.angles.length-1];b.push(d+(a.angles[0]+2*e.PI-d)/2)}a.largestAngle>e.PI&&(b=[a.angleOfLeastInterference]);if(a.bonds)for(let g=0,e=a.bonds.length;g<e;g++)if(d=a.bonds[g],2===d.bondOrder&&(d=d.getNeighbor(a),"O"===d.label)){b=
[d.angle(a)];break}}}else a=a.a1.angle(a.a2),b.push(a+e.PI/2),b.push(a+3*e.PI/2);for(let a=0,d=b.length;a<d;a++){for(;b[a]>2*e.PI;)b[a]-=2*e.PI;for(;0>b[a];)b[a]+=2*e.PI}return b},d=function(a,b){let d=3;if(a instanceof n.Atom){if(a.isLabelVisible(b)&&(d=8),0!==a.charge||0!==a.numRadical||0!==a.numLonePair)d=13}else a instanceof n.Point?d=0:1<a.bondOrder&&(d=5);return d},h=function(a,b,h,f,k,r,u,w,q,y){var c=r.angle(k),g=u.angle(w),l=e.cos(c);c=e.sin(c);var m=d(h,b);k.x-=l*m;k.y+=c*m;m=g+e.PI/2;h=
2*b.shapes_arrowLength_2D/e.sqrt(3);l=e.cos(g);c=e.sin(g);let v=e.cos(m),x=e.sin(m);w.x-=5*l;w.y+=5*c;g=new n.Point(w.x,w.y);m=d(f,b)/3;g.x-=l*m;g.y+=c*m;w.x-=l*(.8*h+m);w.y+=c*(.8*h+m);f=g.x-l*h*.8;m=g.y+c*h*.8;let z=new n.Point(g.x+v*b.shapes_arrowLength_2D/3-l*h,g.y-x*b.shapes_arrowLength_2D/3+c*h);b=new n.Point(g.x-v*b.shapes_arrowLength_2D/3-l*h,g.y+x*b.shapes_arrowLength_2D/3+c*h);c=l=!0;1===q&&(z.distance(r)>b.distance(r)?c=!1:l=!1);a.beginPath();a.moveTo(g.x,g.y);c&&a.lineTo(b.x,b.y);a.lineTo(f,
m);l&&a.lineTo(z.x,z.y);a.closePath();a.fill();a.stroke();a.beginPath();a.moveTo(k.x,k.y);a.bezierCurveTo(r.x,r.y,u.x,u.y,w.x,w.y);a.stroke();y.push([k,r,u,w])};r.Pusher=function(a,b,d){this.o1=a;this.o2=b;this.numElectron=d?d:1};r=r.Pusher.prototype=new r._Shape;r.drawDecorations=function(a,b){if(this.isHover){var d=this.o1 instanceof n.Atom?new n.Point(this.o1.x,this.o1.y):this.o1.getCenter(),g=this.o2 instanceof n.Atom?new n.Point(this.o2.x,this.o2.y):this.o2.getCenter();d=[d,g];for(let e=0,h=
d.length;e<h;e++)g=d[e],this.drawAnchor(a,b,g,g===this.hoverPoint)}};r.draw=function(a,d){if(this.o1&&this.o2){a.strokeStyle=d.shapes_color;a.fillStyle=d.shapes_color;a.lineWidth=d.shapes_lineWidth;a.lineJoin="miter";a.lineCap="butt";let l=this.o1 instanceof n.Atom?new n.Point(this.o1.x,this.o1.y):this.o1.getCenter(),v=this.o2 instanceof n.Atom?new n.Point(this.o2.x,this.o2.y):this.o2.getCenter();var g=b(this.o1),k=b(this.o2);let c,p;var m=Infinity;for(let a=0,b=g.length;a<b;a++)for(let b=0,d=k.length;b<
d;b++){var r=new n.Point(l.x+35*e.cos(g[a]),l.y-35*e.sin(g[a])),u=new n.Point(v.x+35*e.cos(k[b]),v.y-35*e.sin(k[b])),w=r.distance(u);w<m&&(m=w,c=r,p=u)}this.caches=[];-1===this.numElectron?(r=l.distance(v)/2,k=l.angle(v),g=k+e.PI/2,u=e.cos(k),w=e.sin(k),k=new n.Point(l.x+(r-1)*u,l.y-(r-1)*w),m=new n.Point(k.x+35*e.cos(g+e.PI/6),k.y-35*e.sin(g+e.PI/6)),r=new n.Point(l.x+(r+1)*u,l.y-(r+1)*w),g=new n.Point(r.x+35*e.cos(g-e.PI/6),r.y-35*e.sin(g-e.PI/6)),h(a,d,this.o1,k,l,c,m,k,1,this.caches),h(a,d,this.o2,
r,v,p,g,r,1,this.caches)):(f.intersectLines(l.x,l.y,c.x,c.y,v.x,v.y,p.x,p.y)&&(g=c,c=p,p=g),g=c.angle(l),k=p.angle(v),m=e.max(g,k)-e.min(g,k),.001>e.abs(m-e.PI)&&this.o1.molCenter===this.o2.molCenter&&(g+=e.PI/2,k-=e.PI/2,c.x=l.x+35*e.cos(g+e.PI),c.y=l.y-35*e.sin(g+e.PI),p.x=v.x+35*e.cos(k+e.PI),p.y=v.y-35*e.sin(k+e.PI)),h(a,d,this.o1,this.o2,l,c,p,v,this.numElectron,this.caches))}};r.getPoints=function(){return[]};r.isOver=function(a,b){for(let d=0,g=this.caches.length;d<g;d++)if(q.distanceFromCurve(a,
this.caches[d]).distance<b)return!0;return!1}})(ChemDoodle.math,ChemDoodle.lib.jsBezier,ChemDoodle.structures,ChemDoodle.structures.d2,Math);
(function(f,q,n,r,e){let k=new q.Bond;n.VAP=function(b,d){this.asterisk=new q.Atom("O",b,d);this.substituent;this.bondType=1;this.attachments=[]};f=n.VAP.prototype=new n._Shape;f.drawDecorations=function(b,d){if(this.isHover||this.isSelected){b.strokeStyle=this.isHover?d.colorHover:d.colorSelect;b.lineWidth=1.2;if(this.hoverBond){let e=2*r.PI,a=(this.asterisk.angleForStupidCanvasArcs(this.hoverBond)+r.PI/2)%e;b.strokeStyle=this.isHover?d.colorHover:d.colorSelect;b.beginPath();d=(a+r.PI)%e;d%=2*r.PI;
b.arc(this.asterisk.x,this.asterisk.y,7,a,d,!1);b.stroke();b.beginPath();a+=r.PI;d=(a+r.PI)%e;b.arc(this.hoverBond.x,this.hoverBond.y,7,a,d,!1)}else b.beginPath(),b.arc(this.asterisk.x,this.asterisk.y,7,0,2*r.PI,!1);b.stroke()}};f.draw=function(b,d){b.strokeStyle=this.error?d.colorError:d.shapes_color;b.lineWidth=1;var e=r.sqrt(3)/2;b.beginPath();b.moveTo(this.asterisk.x,this.asterisk.y-4);b.lineTo(this.asterisk.x,this.asterisk.y+4);b.moveTo(this.asterisk.x-4*e,this.asterisk.y-2);b.lineTo(this.asterisk.x+
4*e,this.asterisk.y+2);b.moveTo(this.asterisk.x-4*e,this.asterisk.y+2);b.lineTo(this.asterisk.x+4*e,this.asterisk.y-2);b.stroke();this.asterisk.textBounds=[];this.asterisk.textBounds.push({x:this.asterisk.x-4,y:this.asterisk.y-4,w:8,h:8});e=d.bonds_color;this.error&&(d.bonds_color=d.colorError);k.a1=this.asterisk;this.substituent&&(k.a2=this.substituent,k.bondOrder=this.bondType,k.draw(b,d));k.bondOrder=0;this.error||(d.bonds_color=d.shapes_color);for(let a=0,g=this.attachments.length;a<g;a++)k.a2=
this.attachments[a],k.draw(b,d);d.bonds_color=e};f.getPoints=function(){return[this.asterisk]};f.isOver=function(b,d){return!1}})(ChemDoodle.math,ChemDoodle.structures,ChemDoodle.structures.d2,Math);
(function(f,q,n){f._Mesh=function(){};f=f._Mesh.prototype;f.storeData=function(f,e,k){this.positionData=f;this.normalData=e;this.indexData=k};f.setupBuffers=function(f){this.vertexPositionBuffer=f.createBuffer();f.bindBuffer(f.ARRAY_BUFFER,this.vertexPositionBuffer);f.bufferData(f.ARRAY_BUFFER,new Float32Array(this.positionData),f.STATIC_DRAW);this.vertexPositionBuffer.itemSize=3;this.vertexPositionBuffer.numItems=this.positionData.length/3;this.vertexNormalBuffer=f.createBuffer();f.bindBuffer(f.ARRAY_BUFFER,
this.vertexNormalBuffer);f.bufferData(f.ARRAY_BUFFER,new Float32Array(this.normalData),f.STATIC_DRAW);this.vertexNormalBuffer.itemSize=3;this.vertexNormalBuffer.numItems=this.normalData.length/3;this.indexData&&(this.vertexIndexBuffer=f.createBuffer(),f.bindBuffer(f.ELEMENT_ARRAY_BUFFER,this.vertexIndexBuffer),f.bufferData(f.ELEMENT_ARRAY_BUFFER,new Uint16Array(this.indexData),f.STATIC_DRAW),this.vertexIndexBuffer.itemSize=1,this.vertexIndexBuffer.numItems=this.indexData.length);if(this.partitions)for(let e=
0,k=this.partitions.length;e<k;e++){let b=this.partitions[e],d=this.generateBuffers(f,b.positionData,b.normalData,b.indexData);b.vertexPositionBuffer=d[0];b.vertexNormalBuffer=d[1];b.vertexIndexBuffer=d[2]}};f.generateBuffers=function(f,e,k,b){let d=f.createBuffer();f.bindBuffer(f.ARRAY_BUFFER,d);f.bufferData(f.ARRAY_BUFFER,new Float32Array(e),f.STATIC_DRAW);d.itemSize=3;d.numItems=e.length/3;e=f.createBuffer();f.bindBuffer(f.ARRAY_BUFFER,e);f.bufferData(f.ARRAY_BUFFER,new Float32Array(k),f.STATIC_DRAW);
e.itemSize=3;e.numItems=k.length/3;let h;b&&(h=f.createBuffer(),f.bindBuffer(f.ELEMENT_ARRAY_BUFFER,h),f.bufferData(f.ELEMENT_ARRAY_BUFFER,new Uint16Array(b),f.STATIC_DRAW),h.itemSize=1,h.numItems=b.length);return[d,e,h]};f.bindBuffers=function(f){this.vertexPositionBuffer||this.setupBuffers(f);f.bindBuffer(f.ARRAY_BUFFER,this.vertexPositionBuffer);f.vertexAttribPointer(f.shader.vertexPositionAttribute,this.vertexPositionBuffer.itemSize,f.FLOAT,!1,0,0);f.bindBuffer(f.ARRAY_BUFFER,this.vertexNormalBuffer);
f.vertexAttribPointer(f.shader.vertexNormalAttribute,this.vertexNormalBuffer.itemSize,f.FLOAT,!1,0,0);this.vertexIndexBuffer&&f.bindBuffer(f.ELEMENT_ARRAY_BUFFER,this.vertexIndexBuffer)}})(ChemDoodle.structures.d3,Math);
(function(f,q){f._Measurement=function(){};f=f._Measurement.prototype=new f._Mesh;f.render=function(f,r){f.shader.setMatrixUniforms(f);r.measurement_update_3D&&(this.text=this.vertexPositionBuffer=q);this.vertexPositionBuffer||this.calculateData(r);this.bindBuffers(f);f.material.setDiffuseColor(f,r.shapes_color);f.lineWidth(r.shapes_lineWidth);f.drawElements(f.LINES,this.vertexIndexBuffer.numItems,f.UNSIGNED_SHORT,0)};f.renderText=function(f,r){f.shader.setMatrixUniforms(f);this.text||(this.text=
this.getText(r));r={position:[],texCoord:[],translation:[]};f.textImage.pushVertexData(this.text.value,this.text.pos,1,r);f.textMesh.storeData(f,r.position,r.texCoord,r.translation);f.textImage.useTexture(f);f.textMesh.render(f)}})(ChemDoodle.structures.d3);
(function(f,q,n,r,e,k,b,d){n.Angle=function(b,a,d){this.a1=b;this.a2=a;this.a3=d};f=n.Angle.prototype=new n._Measurement;f.calculateData=function(d){let a=[],g=[],h=[];var f=this.a2.distance3D(this.a1),k=this.a2.distance3D(this.a3);this.distUse=e.min(f,k)/2;this.vec1=b.normalize([this.a1.x-this.a2.x,this.a1.y-this.a2.y,this.a1.z-this.a2.z]);this.vec2=b.normalize([this.a3.x-this.a2.x,this.a3.y-this.a2.y,this.a3.z-this.a2.z]);this.angle=q.vec3AngleFrom(this.vec1,this.vec2);f=b.normalize(b.cross(this.vec1,
this.vec2,[]));f=b.normalize(b.cross(f,this.vec1,[]));d=d.measurement_angleBands_3D;for(k=0;k<=d;++k){var n=this.angle*k/d,r=b.scale(this.vec1,e.cos(n),[]);n=b.scale(f,e.sin(n),[]);r=b.scale(b.normalize(b.add(r,n,[])),this.distUse);a.push(this.a2.x+r[0],this.a2.y+r[1],this.a2.z+r[2]);g.push(0,0,0);k<d&&h.push(k,k+1)}this.storeData(a,g,h)};f.getText=function(d){d=b.scale(b.normalize(b.add(this.vec1,this.vec2,[])),this.distUse+.3);return{pos:[this.a2.x+d[0],this.a2.y+d[1],this.a2.z+d[2]],value:[r.angleBounds(this.angle,
!0).toFixed(2)," \u00b0"].join("")}}})(ChemDoodle.ELEMENT,ChemDoodle.extensions,ChemDoodle.structures.d3,ChemDoodle.math,Math,ChemDoodle.lib.mat4,ChemDoodle.lib.vec3);
(function(f,q,n){f.Arrow=function(f,e){let k=[],b=[];for(var d=0;d<=e;d++){var h=2*d*q.PI/e,a=q.sin(h);h=q.cos(h);b.push(0,0,-1,0,0,-1,h,a,0,h,a,0,0,0,-1,0,0,-1,h,a,1,h,a,1);k.push(0,0,0,f*h,f*a,0,f*h,f*a,0,f*h,f*a,2,f*h,f*a,2,f*h*2,f*a*2,2,f*h*2,f*a*2,2,0,0,3)}f=[];for(d=0;d<e;d++){a=8*d;for(let b=0,d=7;b<d;b++){h=b+a;let g=h+d+2;f.push(h,g,h+1,g,h,g-1)}}this.storeData(k,b,f)};f.Arrow.prototype=new f._Mesh})(ChemDoodle.structures.d3,Math);
(function(f,q,n){f.Box=function(f,e,k){f/=2;k/=2;let b=[],d=[];b.push(f,e,-k);b.push(f,e,-k);b.push(-f,e,-k);b.push(f,e,k);b.push(-f,e,k);b.push(-f,e,k);for(var h=6;h--;d.push(0,1,0));b.push(-f,e,k);b.push(-f,e,k);b.push(-f,0,k);b.push(f,e,k);b.push(f,0,k);b.push(f,0,k);for(h=6;h--;d.push(0,0,1));b.push(f,e,k);b.push(f,e,k);b.push(f,0,k);b.push(f,e,-k);b.push(f,0,-k);b.push(f,0,-k);for(h=6;h--;d.push(1,0,0));b.push(f,e,-k);b.push(f,e,-k);b.push(f,0,-k);b.push(-f,e,-k);b.push(-f,0,-k);b.push(-f,0,
-k);for(h=6;h--;d.push(0,0,-1));b.push(-f,e,-k);b.push(-f,e,-k);b.push(-f,0,-k);b.push(-f,e,k);b.push(-f,0,k);b.push(-f,0,k);for(e=6;e--;d.push(-1,0,0));b.push(-f,0,k);b.push(-f,0,k);b.push(-f,0,-k);b.push(f,0,k);b.push(f,0,-k);b.push(f,0,-k);for(f=6;f--;d.push(0,-1,0));this.storeData(b,d)};f.Box.prototype=new f._Mesh})(ChemDoodle.structures.d3,Math);
(function(f,q,n,r,e,k){q.Camera=function(){this.fieldOfView=45;this.aspect=1;this.near=.1;this.far=1E4;this.zoom=1;this.viewMatrix=r.identity([]);this.projectionMatrix=r.identity([])};f=q.Camera.prototype;f.perspectiveProjectionMatrix=function(){let b=e.tan(this.fieldOfView/360*e.PI)*this.near*this.zoom,d=this.aspect*b;return r.frustum(-d,d,-b,b,this.near,this.far,this.projectionMatrix)};f.orthogonalProjectionMatrix=function(){let b=e.tan(this.fieldOfView/360*e.PI)*((this.far-this.near)/2+this.near)*
this.zoom,d=this.aspect*b;return r.ortho(-d,d,-b,b,this.near,this.far,this.projectionMatrix)};f.updateProjectionMatrix=function(b){return b?this.perspectiveProjectionMatrix():this.orthogonalProjectionMatrix()};f.focalLength=function(){return(this.far-this.near)/2+this.near};f.zoomOut=function(){this.zoom=e.min(1.25*this.zoom,200)};f.zoomIn=function(){this.zoom=e.max(this.zoom/1.25,.0025)}})(ChemDoodle.math,ChemDoodle.structures.d3,ChemDoodle.lib.vec3,ChemDoodle.lib.mat4,Math);
(function(f,q,n,r){f.LineArrow=function(){this.storeData([0,0,-3,.1,0,-2.8,0,0,-3,-.1,0,-2.8,0,0,-3,0,0,3,0,0,3,.1,0,2.8,0,0,3,-.1,0,2.8],[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0])};f.LineArrow.prototype=new f._Mesh;f.Compass=function(e,b){this.textImage=new f.TextImage;this.textImage.init(e);this.textImage.updateFont(e,b.text_font_size,b.text_font_families,b.text_font_bold,b.text_font_italic,b.text_font_stroke_3D);this.textMesh=new f.TextMesh;this.textMesh.init(e);var d=3/(b.compass_size_3D/
e.canvas.clientHeight),h=q.tan(b.projectionPerspectiveVerticalFieldOfView_3D/360*q.PI);let a=d/h,g=q.max(a-d,.1);var k=e.canvas.clientWidth/e.canvas.clientHeight;let v;if(b.projectionPerspective_3D){var m=g;v=n.frustum}else m=a,v=n.ortho;let r=m/e.canvas.clientHeight*2*h;h*=m;m=-h;let u=k*m;k*=h;if(0===b.compass_type_3D){let a=(-(e.canvas.clientWidth-b.compass_size_3D)/2+this.textImage.charHeight)*r;b=(-(e.canvas.clientHeight-b.compass_size_3D)/2+this.textImage.charHeight)*r;u-=a;k-=a;m-=b;h-=b}this.projectionMatrix=
v(u,k,m,h,g,a+d);this.translationMatrix=n.translate(n.identity([]),[0,0,-a]);d={position:[],texCoord:[],translation:[]};this.textImage.pushVertexData("X",[3.5,0,0],0,d);this.textImage.pushVertexData("Y",[0,3.5,0],0,d);this.textImage.pushVertexData("Z",[0,0,3.5],0,d);this.textMesh.storeData(e,d.position,d.texCoord,d.translation)};let e=f.Compass.prototype;e.renderArrow=function(e,b,d,h){e.material.setDiffuseColor(e,d);e.shader.setModelViewMatrix(e,h);1===b?e.drawArrays(e.LINES,0,e.lineArrowBuffer.vertexPositionBuffer.numItems):
e.drawElements(e.TRIANGLES,e.arrowBuffer.vertexIndexBuffer.numItems,e.UNSIGNED_SHORT,0)};e.render=function(e,b){e.shader.setProjectionMatrix(e,this.projectionMatrix);1===b.compass_type_3D?e.lineArrowBuffer.bindBuffers(e):e.arrowBuffer.bindBuffers(e);e.material.setTempColors(e,b.bonds_materialAmbientColor_3D,r,b.bonds_materialSpecularColor_3D,b.bonds_materialShininess_3D);let d=n.multiply(this.translationMatrix,e.rotationMatrix,[]),h=q.PI/2;this.renderArrow(e,b.compass_type_3D,b.compass_axisXColor_3D,
n.rotateY(d,h,[]));this.renderArrow(e,b.compass_type_3D,b.compass_axisYColor_3D,n.rotateX(d,-h,[]));this.renderArrow(e,b.compass_type_3D,b.compass_axisZColor_3D,d)};e.renderAxis=function(e){e.shader.setProjectionMatrix(e,this.projectionMatrix);let b=n.multiply(this.translationMatrix,e.rotationMatrix,[]);e.shader.setModelViewMatrix(e,b);this.textImage.useTexture(e);this.textMesh.render(e)}})(ChemDoodle.structures.d3,Math,ChemDoodle.lib.mat4);
(function(f,q,n){f.Cylinder=function(f,e,k,b){let d=[],h=[];if(b){for(b=0;b<=k;b++){var a=b%k*2*q.PI/k,g=q.cos(a);a=q.sin(a);h.push(0,-1,0);d.push(0,0,0);h.push(0,-1,0);d.push(f*g,0,f*a)}for(b=0;b<=k;b++)a=b%k*2*q.PI/k,g=q.cos(a),a=q.sin(a),h.push(g,0,a),d.push(f*g,0,f*a),h.push(g,0,a),d.push(f*g,e,f*a);for(b=0;b<=k;b++)a=b%k*2*q.PI/k,g=q.cos(a),a=q.sin(a),h.push(0,1,0),d.push(f*g,e,f*a),h.push(0,1,0),d.push(0,e,0)}else{for(b=0;b<k;b++)a=2*b*q.PI/k,g=q.cos(a),a=q.sin(a),h.push(g,0,a),d.push(f*g,0,
f*a),h.push(g,0,a),d.push(f*g,e,f*a);h.push(1,0,0);d.push(f,0,0);h.push(1,0,0);d.push(f,e,0)}this.storeData(d,h)};f.Cylinder.prototype=new f._Mesh})(ChemDoodle.structures.d3,Math);
(function(f,q,n,r,e){q.Distance=function(e,b,d,f){this.a1=e;this.a2=b;this.node=d;this.offset=f?f:0};q=q.Distance.prototype=new q._Measurement;q.calculateData=function(e){let b=[this.a1.x,this.a1.y,this.a1.z,this.a2.x,this.a2.y,this.a2.z];this.node&&(this.move=this.offset+n.max(e.atoms_useVDWDiameters_3D?f[this.a1.label].vdWRadius*e.atoms_vdwMultiplier_3D:e.atoms_sphereDiameter_3D/2,e.atoms_useVDWDiameters_3D?f[this.a2.label].vdWRadius*e.atoms_vdwMultiplier_3D:e.atoms_sphereDiameter_3D/2),this.displacement=
[(this.a1.x+this.a2.x)/2-this.node.x,(this.a1.y+this.a2.y)/2-this.node.y,(this.a1.z+this.a2.z)/2-this.node.z],r.normalize(this.displacement),e=r.scale(this.displacement,this.move,[]),b[0]+=e[0],b[1]+=e[1],b[2]+=e[2],b[3]+=e[0],b[4]+=e[1],b[5]+=e[2]);this.storeData(b,[0,0,0,0,0,0],[0,1])};q.getText=function(e){e=this.a1.distance3D(this.a2);let b=[(this.a1.x+this.a2.x)/2,(this.a1.y+this.a2.y)/2,(this.a1.z+this.a2.z)/2];if(this.node){let d=r.scale(this.displacement,this.move+.1,[]);b[0]+=d[0];b[1]+=
d[1];b[2]+=d[2]}return{pos:b,value:[e.toFixed(2)," \u212b"].join("")}}})(ChemDoodle.ELEMENT,ChemDoodle.structures.d3,Math,ChemDoodle.lib.vec3);(function(f,q,n,r){q.Fog=function(e,f,b,d){this.fogScene(e,f,b,d)};q.Fog.prototype.fogScene=function(e,k,b,d){this.colorRGB=f.getRGB(e,1);this.fogStart=k;this.fogEnd=b;this.density=d}})(ChemDoodle.math,ChemDoodle.structures.d3,ChemDoodle.lib.vec3);
(function(f,q,n){q.Label=function(f){};q=q.Label.prototype;q.updateVerticesBuffer=function(r,e,k){for(let l=0,v=e.length;l<v;l++){var b=e[l];let m=b.labelMesh;var d=b.atoms;let v={position:[],texCoord:[],translation:[]};var h=0<d.length&&d[0].hetatm!=n;for(let b=0,e=d.length;b<e;b++){var a=d[b],g=a.label;let e=.05;k.atoms_useVDWDiameters_3D?(g=f[g].vdWRadius*k.atoms_vdwMultiplier_3D,0===g&&(g=1),e+=g):k.atoms_sphereDiameter_3D&&(e+=k.atoms_sphereDiameter_3D/2*1.5);if(h)if(!a.hetatm){if(!k.macro_displayAtoms)continue}else if(a.isWater&&
!k.macro_showWaters)continue;r.textImage.pushVertexData(a.altLabel?a.altLabel:a.label,[a.x,a.y,a.z],e,v)}if((b=b.chains)&&(k.proteins_displayRibbon||k.proteins_displayBackbone))for(let g=0,e=b.length;g<e;g++){d=b[g];for(let b=0,g=d.length;b<g;b++)h=d[b],h.name&&(a=h.cp1,r.textImage.pushVertexData(h.name,[a.x,a.y,a.z],2,v))}m.storeData(r,v.position,v.texCoord,v.translation,v.zDepth)}};q.render=function(f,e,k){f.shader.setMatrixUniforms(f);f.textImage.useTexture(f);for(let b=0,d=k.length;b<d;b++)k[b].labelMesh&&
k[b].labelMesh.render(f)}})(ChemDoodle.ELEMENT,ChemDoodle.structures.d3);(function(f,q,n){f.Sphere=function(f,e,k){let b=[],d=[];for(var h=0;h<=e;h++){var a=h*q.PI/e,g=q.sin(a);a=q.cos(a);for(var l=0;l<=k;l++){var v=2*l*q.PI/k,m=q.sin(v);v=q.cos(v)*g;let e=a;m*=g;d.push(v,e,m);b.push(f*v,f*e,f*m)}}f=[];k+=1;for(h=0;h<e;h++)for(g=0;g<k;g++)a=h*k+g%k,l=a+k,f.push(a,a+1,l),g<k-1&&f.push(l,a+1,l+1);this.storeData(b,d,f)};f.Sphere.prototype=new f._Mesh})(ChemDoodle.structures.d3,Math);
(function(f,q,n,r,e){function k(b,e,a,g){this.entire=b;this.name=e;this.indexes=a;this.pi=g}let b=k.prototype;b.getColor=function(b){return b.macro_colorByChain?this.entire.chainColor:this.name?this.getResidueColor(f[this.name]?this.name:"*",b):this.helix?this.entire.front?b.proteins_ribbonCartoonHelixPrimaryColor:b.proteins_ribbonCartoonHelixSecondaryColor:this.sheet?b.proteins_ribbonCartoonSheetColor:this.entire.front?b.proteins_primaryColor:b.proteins_secondaryColor};b.getResidueColor=function(b,
e){b=f[b];if("shapely"===e.proteins_residueColor)return b.shapelyColor;if("amino"===e.proteins_residueColor)return b.aminoColor;if("polarity"===e.proteins_residueColor){if(b.polar)return"#C10000"}else if("acidity"===e.proteins_residueColor){if(1===b.acidity)return"#0000FF";if(-1===b.acidity)return"#FF0000";if(!b.polar)return"#773300"}return"#FFFFFF"};b.render=function(b,e,a){if(this.entire.partitions&&this.pi!==this.entire.partitions.lastRender){var d=this.entire.partitions[this.pi];b.bindBuffer(b.ARRAY_BUFFER,
d.vertexPositionBuffer);b.vertexAttribPointer(b.shader.vertexPositionAttribute,d.vertexPositionBuffer.itemSize,b.FLOAT,!1,0,0);b.bindBuffer(b.ARRAY_BUFFER,d.vertexNormalBuffer);b.vertexAttribPointer(b.shader.vertexNormalAttribute,d.vertexNormalBuffer.itemSize,b.FLOAT,!1,0,0);b.bindBuffer(b.ELEMENT_ARRAY_BUFFER,d.vertexIndexBuffer);this.entire.partitions.lastRender=this.pi}this.vertexIndexBuffer||(this.vertexIndexBuffer=b.createBuffer(),b.bindBuffer(b.ELEMENT_ARRAY_BUFFER,this.vertexIndexBuffer),b.bufferData(b.ELEMENT_ARRAY_BUFFER,
new Uint16Array(this.indexes),b.STATIC_DRAW),this.vertexIndexBuffer.itemSize=1,this.vertexIndexBuffer.numItems=this.indexes.length);b.bindBuffer(b.ELEMENT_ARRAY_BUFFER,this.vertexIndexBuffer);a||"rainbow"===e.proteins_residueColor||b.material.setDiffuseColor(b,this.getColor(e));b.drawElements(b.TRIANGLES,this.vertexIndexBuffer.numItems,b.UNSIGNED_SHORT,0)};q.Ribbon=function(b,f,a){let d=b[0].lineSegments.length,h=b[0].lineSegments[0].length;this.partitions=[];this.partitions.lastRender=0;this.front=
0<f;for(let g=0,e=b.length;g<e;g++){if(!v||65E3<v.positionData.length){0<this.partitions.length&&g--;var v={count:0,positionData:[],normalData:[]};this.partitions.push(v)}var m=b[g];v.count++;for(var x=0;x<d;x++){var u=a?m.lineSegmentsCartoon[x]:m.lineSegments[x],w=0===x,q=!1;for(var y=0;y<h;y++){var c=u[y],p=g,A=y+1;g===b.length-1&&y===h-1?A--:y===h-1&&(p++,A=0);A=a?b[p].lineSegmentsCartoon[x][A]:b[p].lineSegments[x][A];p=!1;var C=x+1;x===d-1&&(C-=2,p=!0);C=a?m.lineSegmentsCartoon[C][y]:m.lineSegments[C][y];
A=[A.x-c.x,A.y-c.y,A.z-c.z];C=[C.x-c.x,C.y-c.y,C.z-c.z];let e=r.cross(A,C,[]);0===y&&(r.normalize(A),r.scale(A,-1),v.normalData.push(A[0],A[1],A[2]),v.positionData.push(c.x,c.y,c.z));w||q?(r.normalize(C),r.scale(C,-1),v.normalData.push(C[0],C[1],C[2]),v.positionData.push(c.x,c.y,c.z),w&&y===h-1&&(w=!1,y=-1)):(r.normalize(e),(p&&!this.front||!p&&this.front)&&r.scale(e,-1),v.normalData.push(e[0],e[1],e[2]),r.scale(e,n.abs(f)),v.positionData.push(c.x+e[0],c.y+e[1],c.z+e[2]),x===d-1&&y===h-1&&(q=!0,y=
-1));if(-1===y||y===h-1)r.normalize(A),v.normalData.push(A[0],A[1],A[2]),v.positionData.push(c.x,c.y,c.z)}}}d+=2;h+=2;this.segments=[];this.partitionSegments=[];for(let g=0,l=this.partitions.length;g<l;g++){f=this.partitions[g];v=[];m=e;for(let l=0,n=f.count-1;l<n;l++){m=l;for(x=0;x<g;x++)m+=this.partitions[x].count-1;m=b[m];u=l*d*h;x=[];for(let a=0,b=d-1;a<b;a++)for(w=u+a*h,q=0;q<h-1;q++)y=1,l===n&&(y=0),y=[w+q,w+h+q,w+h+q+y,w+q,w+q+y,w+h+q+y],q!==h-1&&(this.front?x.push(y[0],y[1],y[2],y[3],y[5],
y[4]):x.push(y[0],y[2],y[1],y[3],y[4],y[5])),q!==h-2||l===f.count-2&&g===this.partitions.length-1||(c=d*h-q,y[2]+=c,y[4]+=c,y[5]+=c),this.front?v.push(y[0],y[1],y[2],y[3],y[5],y[4]):v.push(y[0],y[2],y[1],y[3],y[4],y[5]);a&&m.split&&(v=new k(this,e,v,g),v.helix=m.helix,v.sheet=m.sheet,this.partitionSegments.push(v),v=[]);this.segments.push(new k(this,m.name,x,g))}f=new k(this,e,v,g);f.helix=m.helix;f.sheet=m.sheet;this.partitionSegments.push(f)}this.storeData(this.partitions[0].positionData,this.partitions[0].normalData);
1===this.partitions.length&&(this.partitions=e)};(q.Ribbon.prototype=new q._Mesh).render=function(b,f){this.bindBuffers(b);let a=f.macro_colorByChain?this.chainColor:e;a||(a=this.front?f.proteins_primaryColor:f.proteins_secondaryColor);b.material.setDiffuseColor(b,a);for(let a=0,d=this.partitionSegments.length;a<d;a++)this.partitionSegments[a].render(b,f,!f.proteins_ribbonCartoonize)}})(ChemDoodle.RESIDUE,ChemDoodle.structures.d3,Math,ChemDoodle.lib.vec3);
(function(f,q,n,r,e){q.Light=function(e,b,d){this.camera=new q.Camera;this.lightScene(e,b,d)};e=q.Light.prototype;e.lightScene=function(e,b,d){this.diffuseRGB=f.getRGB(e,1);this.specularRGB=f.getRGB(b,1);this.direction=d;this.updateView()};e.updateView=function(){var e=n.normalize(this.direction,[]);let b=n.scale(e,(this.camera.near-this.camera.far)/2-this.camera.near,[]);e=n.equal(e,[0,1,0])?[0,0,1]:[0,1,0];r.lookAt(b,[0,0,0],e,this.camera.viewMatrix);this.camera.orthogonalProjectionMatrix()}})(ChemDoodle.math,
ChemDoodle.structures.d3,ChemDoodle.lib.vec3,ChemDoodle.lib.mat4);(function(f,q){f.Line=function(){this.storeData([0,0,0,0,1,0],[0,0,0,0,0,0])};f.Line.prototype=new f._Mesh})(ChemDoodle.structures.d3);
(function(f,q,n){q.Material=function(){};q=q.Material.prototype;q.setTempColors=function(n,e,k,b,d){e&&n.shader.setMaterialAmbientColor(n,f.getRGB(e,1));k&&n.shader.setMaterialDiffuseColor(n,f.getRGB(k,1));b&&n.shader.setMaterialSpecularColor(n,f.getRGB(b,1));n.shader.setMaterialShininess(n,d);n.shader.setMaterialAlpha(n,1)};q.setDiffuseColor=function(n,e){n.shader.setMaterialDiffuseColor(n,f.getRGB(e,1))};q.setAlpha=function(f,e){f.shader.setMaterialAlpha(f,e)}})(ChemDoodle.math,ChemDoodle.structures.d3);
(function(f,q,n,r){f.Picker=function(){};f=f.Picker.prototype;f.init=function(e){this.framebuffer=e.createFramebuffer();let f=e.createTexture(),b=e.createRenderbuffer();e.bindTexture(e.TEXTURE_2D,f);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_MAG_FILTER,e.NEAREST);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_MIN_FILTER,e.NEAREST);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_WRAP_S,e.CLAMP_TO_EDGE);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_WRAP_T,e.CLAMP_TO_EDGE);e.bindRenderbuffer(e.RENDERBUFFER,b);e.bindFramebuffer(e.FRAMEBUFFER,
this.framebuffer);e.framebufferTexture2D(e.FRAMEBUFFER,e.COLOR_ATTACHMENT0,e.TEXTURE_2D,f,0);e.framebufferRenderbuffer(e.FRAMEBUFFER,e.DEPTH_ATTACHMENT,e.RENDERBUFFER,b);e.bindTexture(e.TEXTURE_2D,null);e.bindRenderbuffer(e.RENDERBUFFER,null);e.bindFramebuffer(e.FRAMEBUFFER,null)};f.setDimension=function(e,f,b){e.bindFramebuffer(e.FRAMEBUFFER,this.framebuffer);var d=e.getFramebufferAttachmentParameter(e.FRAMEBUFFER,e.DEPTH_ATTACHMENT,e.FRAMEBUFFER_ATTACHMENT_OBJECT_NAME);e.isRenderbuffer(d)&&(e.bindRenderbuffer(e.RENDERBUFFER,
d),e.renderbufferStorage(e.RENDERBUFFER,e.DEPTH_COMPONENT16,f,b),e.bindRenderbuffer(e.RENDERBUFFER,null));d=e.getFramebufferAttachmentParameter(e.FRAMEBUFFER,e.COLOR_ATTACHMENT0,e.FRAMEBUFFER_ATTACHMENT_OBJECT_NAME);e.isTexture(d)&&(e.bindTexture(e.TEXTURE_2D,d),e.texImage2D(e.TEXTURE_2D,0,e.RGBA,f,b,0,e.RGBA,e.UNSIGNED_BYTE,null),e.bindTexture(e.TEXTURE_2D,null));e.bindFramebuffer(e.FRAMEBUFFER,null)}})(ChemDoodle.structures.d3,ChemDoodle.math,document);
(function(f,q,n){f.Pill=function(f,e,k,b){var d=1,h=2*f;e-=h;0>e?(d=0,e+=h):e<h&&(d=e/h,e=h);h=[];let a=[];for(var g=0;g<=k;g++){var l=g*q.PI/k,v=q.sin(l);l=q.cos(l)*d;for(let d=0;d<=b;d++){var m=2*d*q.PI/b,n=q.sin(m);m=q.cos(m)*v;let u=l;n*=v;a.push(m,u,n);h.push(f*m,f*u+(g<k/2?e:0),f*n)}}f=[];b+=1;for(e=0;e<k;e++)for(d=0;d<b;d++)g=e*b+d%b,v=g+b,f.push(g,g+1,v),d<b-1&&f.push(v,g+1,v+1);this.storeData(h,a,f)};f.Pill.prototype=new f._Mesh})(ChemDoodle.structures.d3,Math);
(function(f,q,n,r,e,k,b,d,h){function a(a,b,d){let g=new n.Residue(-1);g.cp1=g.cp2=new n.Atom("",a,b,d);return g}function g(a,b){this.a1=a;this.a2=b}function l(a,b,d){this.a1=a;this.a2=b;this.vx=d}g.prototype.render=function(a,d){var g=this.a1;let h=this.a2;var l=1.001*g.distance3D(h);d=d.proteins_cylinderHelixDiameter/2;l=[d,l,d];d=k.translate(k.identity(),[g.x,g.y,g.z]);var m=[0,1,0];let v=0;g.x===h.x&&g.z===h.z?(m=[0,0,1],h.y<g.y&&(v=e.PI)):(g=[h.x-g.x,h.y-g.y,h.z-g.z],v=f.vec3AngleFrom(m,g),m=
b.cross(m,g,[]));0!==v&&k.rotate(d,v,m);k.scale(d,l);a.shader.setMatrixUniforms(a,d);a.drawArrays(a.TRIANGLE_STRIP,0,a.cylinderClosedBuffer.vertexPositionBuffer.numItems)};l.prototype.render=function(a,d){this.styles&&(d=this.styles);let g=1.001*this.a1.distance3D(this.a2);var e=[this.a2.x-this.a1.x,this.a2.y-this.a1.y,this.a2.z-this.a1.z];let f=b.cross(e,this.vx,[]),h=b.cross(f,e,[]);b.normalize(h);b.normalize(e);b.normalize(f);e=[h[0],h[1],h[2],0,e[0],e[1],e[2],0,f[0],f[1],f[2],0,this.a1.x,this.a1.y,
this.a1.z,1];k.scale(e,[d.proteins_plankSheetWidth,g,d.proteins_tubeThickness]);a.shader.setMatrixUniforms(a,e);a.drawArrays(a.TRIANGLE_STRIP,0,a.boxBuffer.vertexPositionBuffer.numItems)};r.PipePlank=function(d,f){this.tubes=[];this.helixCylinders=[];this.sheetPlanks=[];this.chainColor=d.chainColor;var h=[],k=[],m=[],v=[];if(1<d.length){var q=d[0],c=d[1];c.helix?m.push(q):c.sheet?v.push(q):k.push(q)}for(let f=1,u=d.length-1;f<=u;f++)if(q=d[f],q.helix){if(m.push(q),q.arrow){var p=b.create();c=b.create();
if(1===m.length)p=[q.guidePointsSmall[0].x,q.guidePointsSmall[0].y,q.guidePointsSmall[0].z],c=q.guidePointsSmall[q.guidePointsSmall.length-1],c=[c.x,c.y,c.z];else if(2===m.length)p=[m[0].cp1.x,m[0].cp1.y,m[0].cp1.z],c=[m[1].cp1.x,m[1].cp1.y,m[1].cp1.z];else{3===m.length&&m.unshift(d[e.max(f-3,0)]);var A=[],C=[];for(let a=1,c=m.length-1;a<c;a++){var B=[m[a].cp1.x,m[a].cp1.y,m[a].cp1.z],D=[m[a-1].cp1.x,m[a-1].cp1.y,m[a-1].cp1.z],E=[m[a+1].cp1.x,m[a+1].cp1.y,m[a+1].cp1.z];b.subtract(D,B);b.subtract(E,
B);var K=b.scale(D,b.length(E),[]);D=b.scale(E,b.length(D),[]);K=b.normalize(b.add(K,D,[]));A.push(B);C.push(K)}m=[];for(let a=0,c=A.length-1;a<c;a++){D=A[a];E=C[a];B=A[a+1];K=C[a+1];var G=b.normalize(b.cross(E,K,[])),J=b.subtract(B,D,[]);let c=b.dot(J,G);G=b.scale(G,c,[]);G=b.length(G);J=b.length(J);J=-(G*G-J*J)/(2*b.dot(b.subtract(D,B,[]),K));D=b.add(D,b.scale(E,J,[]),[]);B=b.add(B,b.scale(K,J,[]),[]);m.push([D,B])}A=m[0][0];C=m[0][1];C=b.subtract(A,C,[]);b.add(A,C,p);A=m[m.length-1][1];C=m[m.length-
1][0];C=b.subtract(A,C,[]);b.add(A,C,c)}m=new n.Atom("",p[0],p[1],p[2]);A=new n.Atom("",c[0],c[1],c[2]);this.helixCylinders.push(new g(m,A));m=[];A=b.subtract(p,c,[]);b.normalize(A);b.scale(A,.5);0<k.length&&(C=b.add(p,A,[]),B=k[k.length-1].cp1,B=b.subtract([B.x,B.y,B.z],C,[]),b.normalize(B),b.scale(B,.5),b.add(C,B),B=new n.Residue(-1),B.cp1=B.cp2=new n.Atom("",C[0],C[1],C[2]),k.push(B),B=a(p[0],p[1],p[2]),k.push(B),h.push(k));k=[];f<u&&(p=a(c[0],c[1],c[2]),k.push(p),p=d[f+1],p.sheet?(k.push(q),k.push(q),
h.push(k),k=[],v.push(q)):(b.scale(A,-1),q=b.add(c,A,[]),c=p.cp1,c=b.subtract([c.x,c.y,c.z],q,[]),b.normalize(c),b.scale(c,.5),b.add(q,c),q=a(q[0],q[1],q[2]),k.push(q)))}}else if(q.sheet){if(v.push(q),q.arrow){p=[0,0,0];A=[0,0,0];c=v.length;for(C=0;C<c;C++)K=v[C].guidePointsLarge,B=K[0],K=K[K.length-1],b.add(p,[B.x,B.y,B.z]),b.add(A,[K.x,K.y,K.z]);b.scale(p,1/c);b.scale(A,1/c);p=b.subtract(p,A);c=v[c-1].guidePointsSmall[0];this.sheetPlanks.push(new l(v[0].guidePointsSmall[0],c,p));v=[];f<u&&(d[f+
1].sheet?v.push(q):(q=a(c.x,c.y,c.z),k.push(q)))}}else k.push(q),f<u&&d[f+1].sheet&&(c=q.guidePointsSmall[0],c=a(c.x,c.y,c.z),k.push(c),h.push(k),k=[],v.push(q));1<k.length&&(2==k.length&&k.push(k[k.length-1]),h.push(k));k=[];for(let a=0,b=h.length;a<b;a++){v=h[a];q=[];for(let a=0,b=v.length-1;a<=b;a++)q.push(v[a].cp1);k.push(q)}for(let a=0,b=k.length;a<b;a++)h=new r.CatmullTube(k[a],f.proteins_tubeThickness,f.proteins_tubeResolution_3D,f.proteins_horizontalResolution),h.chainColor=d.chainColor,this.tubes.push(h)};
(r.PipePlank.prototype=new r._Mesh).render=function(a,b){a.material.setTempColors(a,b.proteins_materialAmbientColor_3D,h,b.proteins_materialSpecularColor_3D,b.proteins_materialShininess_3D);a.material.setDiffuseColor(a,b.macro_colorByChain?this.chainColor:b.proteins_tubeColor);for(let d=0,g=this.tubes.length;d<g;d++)a.shader.setMatrixUniforms(a),this.tubes[d].render(a,b);b.macro_colorByChain||a.material.setDiffuseColor(a,b.proteins_ribbonCartoonHelixSecondaryColor);a.cylinderClosedBuffer.bindBuffers(a);
for(let d=0,g=this.helixCylinders.length;d<g;d++)this.helixCylinders[d].render(a,b);b.macro_colorByChain||a.material.setDiffuseColor(a,b.proteins_ribbonCartoonSheetColor);a.boxBuffer.bindBuffers(a);for(let d=0,g=this.sheetPlanks.length;d<g;d++)this.sheetPlanks[d].render(a,b)}})(ChemDoodle.extensions,ChemDoodle.RESIDUE,ChemDoodle.structures,ChemDoodle.structures.d3,Math,ChemDoodle.lib.mat4,ChemDoodle.lib.vec3,ChemDoodle.math);
(function(f,q){f.Quad=function(){this.storeData([-1,1,0,-1,-1,0,1,1,0,1,-1,0],[0,0,0,0,0,0,0,0,0,0,0,0])};f.Quad.prototype=new f._Mesh})(ChemDoodle.structures.d3);
(function(f,q,n,r){q.Shape=function(e,k){var b=e.length;let d=[],h=[],a=new f.Point;for(let f=0,m=b;f<m;f++){var g=f+1;f===m-1&&(g=0);let b=e[f];var l=e[g];g=n.cross([0,0,1],[l.x-b.x,l.y-b.y,0]);for(let a=0;2>a;a++)d.push(b.x,b.y,k/2),d.push(b.x,b.y,-k/2),d.push(l.x,l.y,k/2),d.push(l.x,l.y,-k/2);for(l=0;4>l;l++)h.push(g[0],g[1],g[2]);h.push(0,0,1);h.push(0,0,-1);h.push(0,0,1);h.push(0,0,-1);a.add(b)}a.x/=b;a.y/=b;h.push(0,0,1);d.push(a.x,a.y,k/2);h.push(0,0,-1);d.push(a.x,a.y,-k/2);e=[];k=8*b;for(let a=
0,d=b;a<d;a++)b=8*a,e.push(b),e.push(b+3),e.push(b+1),e.push(b),e.push(b+2),e.push(b+3),e.push(b+4),e.push(k),e.push(b+6),e.push(b+5),e.push(b+7),e.push(k+1);this.storeData(d,h,e)};q.Shape.prototype=new q._Mesh})(ChemDoodle.structures,ChemDoodle.structures.d3,ChemDoodle.lib.vec3);
(function(f,q,n,r){f.Star=function(){let e=[.8944,.4472,0,.2764,.4472,.8506,.2764,.4472,-.8506,-.7236,.4472,.5257,-.7236,.4472,-.5257,-.3416,.4472,0,-.1056,.4472,.3249,-.1056,.4472,-.3249,.2764,.4472,.2008,.2764,.4472,-.2008,-.8944,-.4472,0,-.2764,-.4472,.8506,-.2764,-.4472,-.8506,.7236,-.4472,.5257,.7236,-.4472,-.5257,.3416,-.4472,0,.1056,-.4472,.3249,.1056,-.4472,-.3249,-.2764,-.4472,.2008,-.2764,-.4472,-.2008,-.5527,.1058,0,-.1708,.1058,.5527,-.1708,.1058,-.5527,.4471,.1058,.3249,.4471,.1058,-.3249,
.5527,-.1058,0,.1708,-.1058,.5527,.1708,-.1058,-.5527,-.4471,-.1058,.3249,-.4471,-.1058,-.3249,0,1,0,0,-1,0],f=[0,9,8,2,7,9,4,5,7,3,6,5,1,8,6,0,8,23,30,6,8,3,21,6,11,26,21,13,23,26,2,9,24,30,8,9,1,23,8,13,25,23,14,24,25,4,7,22,30,9,7,0,24,9,14,27,24,12,22,27,3,5,20,30,7,5,2,22,7,12,29,22,10,20,29,1,6,21,30,5,6,4,20,5,10,28,20,11,21,28,10,19,18,12,17,19,14,15,17,13,16,15,11,18,16,31,19,17,14,17,27,2,27,22,4,22,29,10,29,19,31,18,19,12,19,29,4,29,20,3,20,28,11,28,18,31,16,18,10,18,28,3,28,21,1,21,26,
13,26,16,31,15,16,11,16,26,1,26,23,0,23,25,14,25,15,31,17,15,13,15,25,0,25,24,2,24,27,12,27,17],b=[],d=[],h=[];for(let k=0,m=f.length;k<m;k+=3){var a=3*f[k],g=3*f[k+1],l=3*f[k+2];a=[e[a],e[a+1],e[a+2]];g=[e[g],e[g+1],e[g+2]];l=[e[l],e[l+1],e[l+2]];let m=n.cross([l[0]-g[0],l[1]-g[1],l[2]-g[2]],[a[0]-g[0],a[1]-g[1],a[2]-g[2]],[]);n.normalize(m);b.push(a[0],a[1],a[2],g[0],g[1],g[2],l[0],l[1],l[2]);d.push(m[0],m[1],m[2],m[0],m[1],m[2],m[0],m[1],m[2]);h.push(k,k+1,k+2)}this.storeData(b,d,h)};f.Star.prototype=
new f._Mesh})(ChemDoodle.structures.d3,Math,ChemDoodle.lib.vec3);
(function(f,q,n,r,e){let k=1;r.devicePixelRatio&&(k=r.devicePixelRatio);f.TextImage=function(){this.ctx=n.createElement("canvas").getContext("2d");this.data=[];this.text="";this.charHeight=0};f=f.TextImage.prototype;f.init=function(b){this.textureImage=b.createTexture();b.bindTexture(b.TEXTURE_2D,this.textureImage);b.pixelStorei(b.UNPACK_FLIP_Y_WEBGL,!1);b.texParameteri(b.TEXTURE_2D,b.TEXTURE_WRAP_S,b.CLAMP_TO_EDGE);b.texParameteri(b.TEXTURE_2D,b.TEXTURE_WRAP_T,b.CLAMP_TO_EDGE);b.texParameteri(b.TEXTURE_2D,
b.TEXTURE_MIN_FILTER,b.NEAREST);b.texParameteri(b.TEXTURE_2D,b.TEXTURE_MAG_FILTER,b.NEAREST);b.bindTexture(b.TEXTURE_2D,null);this.updateFont(b,12,["Sans-serif"],!1,!1,!1)};f.charData=function(b){b=this.text.indexOf(b);return 0<=b?this.data[b]:null};f.updateFont=function(b,d,e,a,g,f){let h=this.ctx,l=this.ctx.canvas,n=[],u="";d*=k;e=q.getFontString(d,e,a,g);h.font=e;h.save();a=0;d*=1.5;for(let b=32,c=127;b<c;b++){g=String.fromCharCode(b);var w=h.measureText(g).width;n.push({text:g,width:w,height:d});
a+=2*w}g=["\u00b0","\u212b","\u00ae"];for(let b=0,c=g.length;b<c;b++){w=g[b];var r=h.measureText(w).width;n.push({text:w,width:r,height:d});a+=2*r}g=Math.ceil(Math.sqrt(a*d)/d);a=Math.ceil(a/(g-1));l.width=a;l.height=g*d;h.font=e;h.textAlign="left";h.textBaseline="middle";h.strokeStyle="#000";h.lineWidth=1.4;h.fillStyle="#fff";g=e=0;for(let b=0,c=n.length;b<c;b++){w=n[b];r=2*w.width;let c=w.height,d=w.text;g+r>a&&(e++,g=0);let l=e*c;f&&h.strokeText(d,g,l+c/2);h.fillText(d,g,l+c/2);w.x=g;w.y=l;u+=
d;g+=r}this.text=u;this.data=n;this.charHeight=d;b.bindTexture(b.TEXTURE_2D,this.textureImage);b.texImage2D(b.TEXTURE_2D,0,b.RGBA,b.RGBA,b.UNSIGNED_BYTE,l);b.bindTexture(b.TEXTURE_2D,null)};f.pushVertexData=function(b,d,e,a){let g=b.toString().split(""),f=this.getHeight(),h=this.getWidth();b=-this.textWidth(b)/2/k;let m=-this.charHeight/2/k;for(let l=0,v=g.length;l<v;l++){var n=this.charData(g[l]);let v=n.width,u=n.x/h,c=u+1.8*n.width/h,p=n.y/f;n=p+n.height/f;let r=b+1.8*v/k,w=this.charHeight/2/k;
a.position.push(d[0],d[1],d[2],d[0],d[1],d[2],d[0],d[1],d[2],d[0],d[1],d[2],d[0],d[1],d[2],d[0],d[1],d[2]);a.texCoord.push(u,p,c,n,c,p,u,p,u,n,c,n);a.translation.push(b,w,e,r,m,e,r,w,e,b,w,e,b,m,e,r,m,e);b=r+(v-1.8*v)/k}};f.getCanvas=function(){return this.ctx.canvas};f.getHeight=function(){return this.getCanvas().height};f.getWidth=function(){return this.getCanvas().width};f.textWidth=function(b){return this.ctx.measureText(b).width};f.test=function(){n.body.appendChild(this.getCanvas())};f.useTexture=
function(b){b.bindTexture(b.TEXTURE_2D,this.textureImage)}})(ChemDoodle.structures.d3,ChemDoodle.extensions,document,window);
(function(f,q,n){f.TextMesh=function(){};f=f.TextMesh.prototype;f.init=function(f){this.vertexPositionBuffer=f.createBuffer();this.vertexTexCoordBuffer=f.createBuffer();this.vertexTranslationBuffer=f.createBuffer()};f.setVertexData=function(f,e,k,b){f.bindBuffer(f.ARRAY_BUFFER,e);f.bufferData(f.ARRAY_BUFFER,new Float32Array(k),f.STATIC_DRAW);e.itemSize=b;e.numItems=k.length/b};f.storeData=function(f,e,k,b){this.setVertexData(f,this.vertexPositionBuffer,e,3);this.setVertexData(f,this.vertexTexCoordBuffer,
k,2);this.setVertexData(f,this.vertexTranslationBuffer,b,3)};f.bindBuffers=function(f){f.bindBuffer(f.ARRAY_BUFFER,this.vertexPositionBuffer);f.vertexAttribPointer(f.shader.vertexPositionAttribute,this.vertexPositionBuffer.itemSize,f.FLOAT,!1,0,0);f.bindBuffer(f.ARRAY_BUFFER,this.vertexTexCoordBuffer);f.vertexAttribPointer(f.shader.vertexTexCoordAttribute,this.vertexTexCoordBuffer.itemSize,f.FLOAT,!1,0,0);f.bindBuffer(f.ARRAY_BUFFER,this.vertexTranslationBuffer);f.vertexAttribPointer(f.shader.vertexNormalAttribute,
this.vertexTranslationBuffer.itemSize,f.FLOAT,!1,0,0)};f.render=function(f){let e=this.vertexPositionBuffer.numItems;e&&(this.bindBuffers(f),f.drawArrays(f.TRIANGLES,0,e))}})(ChemDoodle.structures.d3,Math);
(function(f,q,n,r,e,k,b){n.Torsion=function(b,e,a,g){this.a1=b;this.a2=e;this.a3=a;this.a4=g};f=n.Torsion.prototype=new n._Measurement;f.calculateData=function(d){let e=[],a=[],g=[];var f=this.a2.distance3D(this.a1),v=this.a2.distance3D(this.a3);this.distUse=r.min(f,v)/2;v=[this.a2.x-this.a1.x,this.a2.y-this.a1.y,this.a2.z-this.a1.z];f=[this.a3.x-this.a2.x,this.a3.y-this.a2.y,this.a3.z-this.a2.z];var m=[this.a4.x-this.a3.x,this.a4.y-this.a3.y,this.a4.z-this.a3.z],n=k.cross(v,f,[]);m=k.cross(f,m,[]);
k.scale(v,k.length(f));this.torsion=r.atan2(k.dot(v,m),k.dot(n,m));n=k.normalize(k.cross(n,f,[]));v=k.normalize(k.cross(f,n,[]));this.pos=k.add([this.a2.x,this.a2.y,this.a2.z],k.scale(k.normalize(f,[]),this.distUse));m=[];let u=d.measurement_angleBands_3D;var w=b;for(d=0;d<=u;++d){var q=this.torsion*d/u;w=k.scale(n,r.cos(q),[]);q=k.scale(v,r.sin(q),[]);w=k.scale(k.normalize(k.add(w,q,[])),this.distUse);0==d&&(m=w);e.push(this.pos[0]+w[0],this.pos[1]+w[1],this.pos[2]+w[2]);a.push(0,0,0);d<u&&g.push(d,
d+1)}this.vecText=k.normalize(k.add(m,w,[]));f=k.normalize(f,[]);k.scale(f,.0625);m=this.torsion-2*r.asin(.125)*this.torsion/r.abs(this.torsion);n=k.scale(n,r.cos(m),[]);v=k.scale(v,r.sin(m),[]);w=k.scale(k.normalize(k.add(n,v,[])),this.distUse);e.push(this.pos[0]+f[0]+w[0],this.pos[1]+f[1]+w[1],this.pos[2]+f[2]+w[2]);a.push(0,0,0);e.push(this.pos[0]-f[0]+w[0],this.pos[1]-f[1]+w[1],this.pos[2]-f[2]+w[2]);a.push(0,0,0);g.push(--d,d+1,d,d+2);this.storeData(e,a,g)};f.getText=function(b){k.add(this.pos,
k.scale(this.vecText,this.distUse+.3,[]));return{pos:this.pos,value:[q.angleBounds(this.torsion,!0,!0).toFixed(2)," \u00b0"].join("")}}})(ChemDoodle.ELEMENT,ChemDoodle.math,ChemDoodle.structures.d3,Math,ChemDoodle.lib.mat4,ChemDoodle.lib.vec3);
(function(f,q,n,r,e,k,b,d,h){let a=function(a,b){a.bindBuffer(a.ARRAY_BUFFER,b.vertexPositionBuffer);a.vertexAttribPointer(a.shader.vertexPositionAttribute,b.vertexPositionBuffer.itemSize,a.FLOAT,!1,0,0);a.bindBuffer(a.ARRAY_BUFFER,b.vertexNormalBuffer);a.vertexAttribPointer(a.shader.vertexNormalAttribute,b.vertexNormalBuffer.itemSize,a.FLOAT,!1,0,0);a.bindBuffer(a.ELEMENT_ARRAY_BUFFER,b.vertexIndexBuffer)},g=function(a,b,d){let g=e.sqrt(b[1]*b[1]+b[2]*b[2]),f=[1,0,0,0,0,b[2]/g,-b[1]/g,0,0,b[1]/g,
b[2]/g,0,0,0,0,1],h=[1,0,0,0,0,b[2]/g,b[1]/g,0,0,-b[1]/g,b[2]/g,0,0,0,0,1],l=[g,0,-b[0],0,0,1,0,0,b[0],0,g,0,0,0,0,1];b=[g,0,b[0],0,0,1,0,0,-b[0],0,g,0,0,0,0,1];d=[e.cos(d),-e.sin(d),0,0,e.sin(d),e.cos(d),0,0,0,0,1,0,0,0,0,1];let m=k.multiply(f,k.multiply(l,k.multiply(d,k.multiply(b,h,[]))));this.rotate=function(){return k.multiplyVec3(m,a)}};r.Tube=function(h,v,m){var l=h[0].lineSegments[0].length;this.partitions=[];this.ends=[];this.ends.push(h[0].lineSegments[0][0]);this.ends.push(h[h.length-1].lineSegments[0][0]);
var u=[1,0,0];for(let a=0,d=h.length;a<d;a++){if(!w||65E3<w.positionData.length){0<this.partitions.length&&a--;var w={count:0,positionData:[],normalData:[],indexData:[]};this.partitions.push(w)}var r=h[a];w.count++;var y=Infinity,c=new n.Atom("",h[a].cp1.x,h[a].cp1.y,h[a].cp1.z);for(let d=0;d<l;d++){let f=r.lineSegments[0][d];var p=d===l-1?a===h.length-1?r.lineSegments[0][d-1]:h[a+1].lineSegments[0][0]:r.lineSegments[0][d+1];p=[p.x-f.x,p.y-f.y,p.z-f.z];b.normalize(p);a===h.length-1&&d===l-1&&b.scale(p,
-1);var A=b.cross(p,u,[]);b.normalize(A);b.scale(A,v/2);p=new g(A,p,2*Math.PI/m);for(let a=0,b=m;a<b;a++)A=p.rotate(),a===e.floor(m/4)&&(u=[A[0],A[1],A[2]]),w.normalData.push(A[0],A[1],A[2]),w.positionData.push(f.x+A[0],f.y+A[1],f.z+A[2]);c&&(p=f.distance3D(c),p<y&&(y=p,h[a].pPoint=f))}}for(let a=0,b=this.partitions.length;a<b;a++){w=this.partitions[a];for(let a=0,b=w.count-1;a<b;a++){u=a*l*m;for(let a=0,b=l;a<b;a++)for(r=u+a*m,y=0;y<m;y++)c=r+y,w.indexData.push(c),w.indexData.push(c+m),w.indexData.push(c+
m+1),w.indexData.push(c),w.indexData.push(c+m+1),w.indexData.push(c+1)}}this.storeData(this.partitions[0].positionData,this.partitions[0].normalData,this.partitions[0].indexData);m=[new n.Point(2,0)];for(l=0;60>l;l++)w=l/60*e.PI,m.push(new n.Point(2*e.cos(w),-2*e.sin(w)));m.push(new n.Point(-2,0),new n.Point(-2,4),new n.Point(2,4));let C=new n.d3.Shape(m,1);this.render=function(c,g){this.bindBuffers(c);c.material.setDiffuseColor(c,g.macro_colorByChain?this.chainColor:g.nucleics_tubeColor);c.drawElements(c.TRIANGLES,
this.vertexIndexBuffer.numItems,c.UNSIGNED_SHORT,0);if(this.partitions)for(let b=1,d=this.partitions.length;b<d;b++){var l=this.partitions[b];a(c,l);c.drawElements(c.TRIANGLES,l.vertexIndexBuffer.numItems,c.UNSIGNED_SHORT,0)}c.sphereBuffer.bindBuffers(c);for(l=0;2>l;l++){var m=this.ends[l];m=k.translate(k.identity(),[m.x,m.y,m.z]);var p=v/2;k.scale(m,[p,p,p]);c.shader.setMatrixUniforms(c,m);c.drawElements(c.TRIANGLES,c.sphereBuffer.vertexIndexBuffer.numItems,c.UNSIGNED_SHORT,0)}c.cylinderBuffer.bindBuffers(c);
for(let a=0,d=h.length-1;a<d;a++){m=h[a];l=m.pPoint;m=new n.Atom("",m.cp2.x,m.cp2.y,m.cp2.z);p=1.001*l.distance3D(m);p=[v/4,p,v/4];var u=k.translate(k.identity(),[l.x,l.y,l.z]),w=[0,1,0],r=0,x=[m.x-l.x,m.y-l.y,m.z-l.z];l.x===m.x&&l.z===m.z?(m=[0,0,1],l.y<l.y&&(r=e.PI)):(r=f.vec3AngleFrom(w,x),m=b.cross(w,x,[]));0!==r&&k.rotate(u,r,m);k.scale(u,p);c.shader.setMatrixUniforms(c,u);c.drawArrays(c.TRIANGLE_STRIP,0,c.cylinderBuffer.vertexPositionBuffer.numItems)}C.bindBuffers(c);"none"!==g.nucleics_residueColor||
g.macro_colorByChain||c.material.setDiffuseColor(c,g.nucleics_baseColor);for(let a=0,n=h.length-1;a<n;a++)if(l=h[a],u=l.cp2,m=k.translate(k.identity(),[u.x,u.y,u.z]),w=[0,1,0],r=0,x=l.cp3){p=[x.x-u.x,x.y-u.y,x.z-u.z];u.x===x.x&&u.z===x.z?(w=[0,0,1],u.y<u.y&&(r=e.PI)):(r=f.vec3AngleFrom(w,p),w=b.cross(w,p,[]));0!==r&&k.rotate(m,r,w);u=[1,0,0];r=k.rotate(k.identity([]),r,w);k.multiplyVec3(r,u);r=l.cp4;w=l.cp5;if(r.y!==w.y||r.z!==w.z)r=[w.x-r.x,w.y-r.y,w.z-r.z],w=f.vec3AngleFrom(u,r),0>b.dot(p,b.cross(u,
r))&&(w*=-1),k.rotateY(m,w);g.macro_colorByChain||("shapely"===g.nucleics_residueColor?q[l.name]?c.material.setDiffuseColor(c,q[l.name].shapelyColor):c.material.setDiffuseColor(c,q["*"].shapelyColor):"rainbow"===g.nucleics_residueColor&&c.material.setDiffuseColor(c,d.rainbowAt(a,n,g.macro_rainbowColors)));c.shader.setMatrixUniforms(c,m);c.drawElements(c.TRIANGLES,C.vertexIndexBuffer.numItems,c.UNSIGNED_SHORT,0)}}};r.Tube.prototype=new r._Mesh;r.CatmullTube=function(a,d,f,h){var k=[];a.push(a[a.length-
1]);for(let b=0,d=a.length-2;b<=d;b++){var l=a[0==b?0:b-1],m=a[b+0],v=a[b+1],c=a[b==d?b+1:b+2],p=[];for(let a=0;a<h;a++){var r=a/h;b==d&&(r=a/(h-1));r=new n.Atom("C",.5*(2*m.x+(v.x-l.x)*r+(2*l.x-5*m.x+4*v.x-c.x)*r*r+(3*m.x-l.x-3*v.x+c.x)*r*r*r),.5*(2*m.y+(v.y-l.y)*r+(2*l.y-5*m.y+4*v.y-c.y)*r*r+(3*m.y-l.y-3*v.y+c.y)*r*r*r),.5*(2*m.z+(v.z-l.z)*r+(2*l.z-5*m.z+4*v.z-c.z)*r*r+(3*m.z-l.z-3*v.z+c.z)*r*r*r));p.push(r)}k.push(p)}a=k[0].length;this.partitions=[];this.ends=[];this.ends.push(k[0][0]);this.ends.push(k[k.length-
1][0]);h=[1,0,0];for(let n=0,u=k.length;n<u;n++){if(!q||65E3<q.positionData.length){0<this.partitions.length&&n--;var q={count:0,positionData:[],normalData:[],indexData:[]};this.partitions.push(q)}l=k[n];q.count++;for(m=0;m<a;m++){v=l[m];c=m===a-1?n===k.length-1?l[m-1]:k[n+1][0]:l[m+1];c=[c.x-v.x,c.y-v.y,c.z-v.z];b.normalize(c);n===k.length-1&&m===a-1&&b.scale(c,-1);p=b.cross(c,h,[]);b.normalize(p);b.scale(p,d/2);c=new g(p,c,2*Math.PI/f);for(let a=0,b=f;a<b;a++)p=c.rotate(),a===e.floor(f/4)&&(h=[p[0],
p[1],p[2]]),q.normalData.push(p[0],p[1],p[2]),q.positionData.push(v.x+p[0],v.y+p[1],v.z+p[2])}}for(let b=0,c=this.partitions.length;b<c;b++){d=this.partitions[b];for(let b=0,c=d.count-1;b<c;b++){k=b*a*f;for(let b=0,c=a;b<c;b++)for(q=k+b*f,h=0;h<=f;h++)l=q+h%f,d.indexData.push(l,l+f)}}this.storeData(this.partitions[0].positionData,this.partitions[0].normalData,this.partitions[0].indexData)};(r.CatmullTube.prototype=new r._Mesh).render=function(b,d){this.bindBuffers(b);for(let d=0,e=this.partitions.length;d<
e;d++){var g=this.partitions[d];a(b,g);b.drawElements(b.TRIANGLE_STRIP,g.vertexIndexBuffer.numItems,b.UNSIGNED_SHORT,0)}b.sphereBuffer.bindBuffers(b);for(g=0;2>g;g++){var e=this.ends[g];e=k.translate(k.identity(),[e.x,e.y,e.z]);let a=d.proteins_tubeThickness/2;k.scale(e,[a,a,a]);b.shader.setMatrixUniforms(b,e);b.drawElements(b.TRIANGLES,b.sphereBuffer.vertexIndexBuffer.numItems,b.UNSIGNED_SHORT,0)}}})(ChemDoodle.extensions,ChemDoodle.RESIDUE,ChemDoodle.structures,ChemDoodle.structures.d3,Math,ChemDoodle.lib.mat4,
ChemDoodle.lib.vec3,ChemDoodle.math);
(function(f,q,n){f.UnitCell=function(f){this.unitCell=f;let e=[],k=[];var b=function(b,f,a,g){e.push(b[0],b[1],b[2]);e.push(f[0],f[1],f[2]);e.push(a[0],a[1],a[2]);e.push(g[0],g[1],g[2]);for(b=0;4>b;b++)k.push(0,0,0)};b(f.o,f.x,f.xy,f.y);b(f.o,f.y,f.yz,f.z);b(f.o,f.z,f.xz,f.x);b(f.yz,f.y,f.xy,f.xyz);b(f.xyz,f.xz,f.z,f.yz);b(f.xy,f.x,f.xz,f.xyz);f=[];for(b=0;6>b;b++){let d=4*b;f.push(d,d+1,d+1,d+2,d+2,d+3,d+3,d)}this.storeData(e,k,f)};(f.UnitCell.prototype=new f._Mesh).render=function(f,e){f.shader.setMatrixUniforms(f);
this.bindBuffers(f);f.material.setDiffuseColor(f,e.shapes_color);f.lineWidth(e.shapes_lineWidth);f.drawElements(f.LINES,this.vertexIndexBuffer.numItems,f.UNSIGNED_SHORT,0)}})(ChemDoodle.structures.d3,ChemDoodle.lib.vec3);
(function(f,q,n,r){f.Framebuffer=function(){};f=f.Framebuffer.prototype;f.init=function(e){this.framebuffer=e.createFramebuffer()};f.setColorTexture=function(e,f,b){b=b===r?0:b;e.bindFramebuffer(e.FRAMEBUFFER,this.framebuffer);e.bindTexture(e.TEXTURE_2D,f);e.framebufferTexture2D(e.FRAMEBUFFER,e.COLOR_ATTACHMENT0+b,e.TEXTURE_2D,f,0);e.bindTexture(e.TEXTURE_2D,null);e.bindFramebuffer(e.FRAMEBUFFER,null)};f.setColorRenderbuffer=function(e,f,b){b=b===r?0:b;e.bindFramebuffer(e.FRAMEBUFFER,this.framebuffer);
e.bindRenderbuffer(e.RENDERBUFFER,f);e.framebufferRenderbuffer(e.FRAMEBUFFER,e.COLOR_ATTACHMENT0+b,e.RENDERBUFFER,f);e.bindRenderbuffer(e.RENDERBUFFER,null);e.bindFramebuffer(e.FRAMEBUFFER,null)};f.setDepthTexture=function(e,f){e.bindFramebuffer(e.FRAMEBUFFER,this.framebuffer);e.bindTexture(e.TEXTURE_2D,f);e.framebufferTexture2D(e.FRAMEBUFFER,e.DEPTH_ATTACHMENT,e.TEXTURE_2D,f,0);e.bindTexture(e.TEXTURE_2D,null);e.bindFramebuffer(e.FRAMEBUFFER,null)};f.setDepthRenderbuffer=function(e,f){e.bindFramebuffer(e.FRAMEBUFFER,
this.framebuffer);e.bindRenderbuffer(e.RENDERBUFFER,f);e.framebufferRenderbuffer(e.FRAMEBUFFER,e.DEPTH_ATTACHMENT,e.RENDERBUFFER,f);e.bindRenderbuffer(e.RENDERBUFFER,null);e.bindFramebuffer(e.FRAMEBUFFER,null)};f.bind=function(e,f,b){e.bindFramebuffer(e.FRAMEBUFFER,this.framebuffer);e.viewport(0,0,f,b)}})(ChemDoodle.structures.d3,ChemDoodle.math,document);
(function(f,q,n,r){f.Renderbuffer=function(){};f=f.Renderbuffer.prototype;f.init=function(e,f){this.renderbuffer=e.createRenderbuffer();this.format=f};f.setParameter=function(e,f,b){this.width=f;this.height=b;e.bindRenderbuffer(e.RENDERBUFFER,this.renderbuffer);e.renderbufferStorage(e.RENDERBUFFER,this.format,this.width,this.height);e.bindRenderbuffer(e.RENDERBUFFER,null)}})(ChemDoodle.structures.d3,ChemDoodle.math,document);
(function(f,q,n,r){q.SSAO=function(){};f=q.SSAO.prototype;f.initSampleKernel=function(e){let f=[];for(let d=0;d<e;d++){let h=2*n.random()-1,a=2*n.random()-1,g=2*n.random()-1;var b=d/e;b=.1+b*b*.9;h*=b;a*=b;g*=b;f.push(h,a,g)}this.sampleKernel=new Float32Array(f)};f.initNoiseTexture=function(e){let f=[];for(let b=0;16>b;b++)f.push(2*n.random()-1),f.push(2*n.random()-1),f.push(0);this.noiseTexture=e.createTexture();e.bindTexture(e.TEXTURE_2D,this.noiseTexture);e.texImage2D(e.TEXTURE_2D,0,e.RGB,4,4,
0,e.RGB,e.FLOAT,new Float32Array(f));e.texParameteri(e.TEXTURE_2D,e.TEXTURE_MIN_FILTER,e.NEAREST);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_MAG_FILTER,e.NEAREST);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_WRAP_S,e.REPEAT);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_WRAP_T,e.REPEAT);e.bindTexture(e.TEXTURE_2D,null)}})(ChemDoodle.math,ChemDoodle.structures.d3,Math);
(function(f,q,n,r){f.Texture=function(){};f=f.Texture.prototype;f.init=function(e,f,b,d){this.texture=e.createTexture();this.type=f;this.internalFormat=b;this.format=d!==r?d:b;e.bindTexture(e.TEXTURE_2D,this.texture);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_MAG_FILTER,e.NEAREST);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_MIN_FILTER,e.NEAREST);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_WRAP_S,e.CLAMP_TO_EDGE);e.texParameteri(e.TEXTURE_2D,e.TEXTURE_WRAP_T,e.CLAMP_TO_EDGE);e.bindTexture(e.TEXTURE_2D,null)};f.setParameter=
function(e,f,b){this.width=f;this.height=b;e.bindTexture(e.TEXTURE_2D,this.texture);e.texImage2D(e.TEXTURE_2D,0,this.internalFormat,this.width,this.height,0,this.format,this.type,null);e.bindTexture(e.TEXTURE_2D,null)}})(ChemDoodle.structures.d3,ChemDoodle.math,document);
(function(f,q,n,r,e){f._Shader=function(){};f=f._Shader.prototype;f.useShaderProgram=function(e){e.useProgram(this.gProgram);e.shader=this};f.init=function(e){let b=this.getShader(e,"vertex-shader");b||(b=this.loadDefaultVertexShader(e));let d=this.getShader(e,"fragment-shader");d||(d=this.loadDefaultFragmentShader(e));this.gProgram=e.createProgram();e.attachShader(this.gProgram,b);e.attachShader(this.gProgram,d);this.onShaderAttached(e);e.linkProgram(this.gProgram);e.getProgramParameter(this.gProgram,
e.LINK_STATUS)||alert("Could not initialize shaders: "+e.getProgramInfoLog(this.gProgram));e.useProgram(this.gProgram);this.initUniformLocations(e);e.useProgram(null)};f.onShaderAttached=function(e){this.vertexPositionAttribute=0;this.vertexNormalAttribute=1;e.bindAttribLocation(this.gProgram,this.vertexPositionAttribute,"a_vertex_position");e.bindAttribLocation(this.gProgram,this.vertexNormalAttribute,"a_vertex_normal")};f.getShaderFromStr=function(f,b,d){b=f.createShader(b);f.shaderSource(b,d);
f.compileShader(b);return f.getShaderParameter(b,f.COMPILE_STATUS)?b:(alert(shaderScript.type+" "+f.getShaderInfoLog(b)),f.deleteShader(b),e)};f.enableAttribsArray=function(e){e.enableVertexAttribArray(this.vertexPositionAttribute)};f.disableAttribsArray=function(e){e.disableVertexAttribArray(this.vertexPositionAttribute)};f.getShader=function(f,b){b=r.getElementById(b);if(!b)return e;var d=[];let h=b.firstChild;for(;h;)3===h.nodeType&&d.push(h.textContent),h=h.nextSibling;d=d.join("");if("x-shader/x-fragment"===
b.type)f=this.getShaderFromStr(f,f.FRAGMENT_SHADER,d);else if("x-shader/x-vertex"===b.type)f=this.getShaderFromStr(f,f.VERTEX_SHADER,d);else return e;return f};f.initUniformLocations=function(e){this.modelViewMatrixUniform=e.getUniformLocation(this.gProgram,"u_model_view_matrix");this.projectionMatrixUniform=e.getUniformLocation(this.gProgram,"u_projection_matrix")};f.loadDefaultVertexShader=function(e){};f.loadDefaultFragmentShader=function(e){};f.setMatrixUniforms=function(f,b){b===e?this.setModelViewMatrix(f,
f.modelViewMatrix):this.setModelViewMatrix(f,n.multiply(f.modelViewMatrix,b,[]))};f.setProjectionMatrix=function(e,b){e.uniformMatrix4fv(this.projectionMatrixUniform,!1,b)};f.setModelViewMatrix=function(e,b){e.uniformMatrix4fv(this.modelViewMatrixUniform,!1,b)};f.setMaterialAmbientColor=function(e,b){};f.setMaterialDiffuseColor=function(e,b){};f.setMaterialSpecularColor=function(e,b){};f.setMaterialShininess=function(e,b){};f.setMaterialAlpha=function(e,b){}})(ChemDoodle.structures.d3,ChemDoodle.lib.mat3,
ChemDoodle.lib.mat4,document);
(function(f,q,n,r,e){f.FXAAShader=function(){};let k=f._Shader.prototype;f=f.FXAAShader.prototype=new f._Shader;f.initUniformLocations=function(b){k.initUniformLocations.call(this,b);this.buffersizeUniform=b.getUniformLocation(this.gProgram,"u_buffersize");this.antialiasUniform=b.getUniformLocation(this.gProgram,"u_antialias");this.edgeThresholdUniform=b.getUniformLocation(this.gProgram,"u_edge_threshold");this.edgeThresholdMinUniform=b.getUniformLocation(this.gProgram,"u_edge_threshold_min");this.searchStepsUniform=
b.getUniformLocation(this.gProgram,"u_search_steps");this.searchThresholdUniform=b.getUniformLocation(this.gProgram,"u_search_threshold");this.subpixCapUniform=b.getUniformLocation(this.gProgram,"u_subpix_cap");this.subpixTrimUniform=b.getUniformLocation(this.gProgram,"u_subpix_trim")};f.setBuffersize=function(b,d,e){b.uniform2f(this.buffersizeUniform,d,e)};f.setAntialias=function(b,d){b.uniform1f(this.antialiasUniform,d)};f.setEdgeThreshold=function(b,d){b.uniform1f(this.edgeThresholdUniform,d)};
f.setEdgeThresholdMin=function(b,d){b.uniform1f(this.edgeThresholdMinUniform,d)};f.setSearchSteps=function(b,d){b.uniform1i(this.searchStepsUniform,d)};f.setSearchThreshold=function(b,d){b.uniform1f(this.searchThresholdUniform,d)};f.setSubpixCap=function(b,d){b.uniform1f(this.subpixCapUniform,d)};f.setSubpixTrim=function(b,d){b.uniform1f(this.subpixTrimUniform,d)};f.loadDefaultVertexShader=function(b){return this.getShaderFromStr(b,b.VERTEX_SHADER,"precision mediump float;attribute vec3 a_vertex_position;varying vec2 v_texcoord;void main() {gl_Position \x3d vec4(a_vertex_position, 1.);v_texcoord \x3d a_vertex_position.xy * .5 + .5;}")};
f.loadDefaultFragmentShader=function(b){return this.getShaderFromStr(b,b.FRAGMENT_SHADER,"precision mediump float;\nconst int fxaaMaxSearchSteps \x3d 128;\nuniform float u_edge_threshold;\nuniform float u_edge_threshold_min;\nuniform int u_search_steps;\nuniform float u_search_threshold;\nuniform float u_subpix_cap;\nuniform float u_subpix_trim;\nuniform sampler2D u_sampler0;\nuniform vec2 u_buffersize;\nuniform bool u_antialias;\nvarying vec2 v_texcoord;\nfloat FxaaLuma(vec3 rgb) {\nreturn rgb.y * (0.587/0.299) + rgb.x;\n}\nvec3 FxaaLerp3(vec3 a, vec3 b, float amountOfA) {\nreturn (vec3(-amountOfA) * b) + ((a * vec3(amountOfA)) + b);\n}\nvec4 FxaaTexOff(sampler2D tex, vec2 pos, vec2 off, vec2 rcpFrame) {\nreturn texture2D(tex, pos + off * rcpFrame);\n}\nvec3 FxaaPixelShader(vec2 pos, sampler2D tex, vec2 rcpFrame) {\nfloat subpix_trim_scale \x3d (1.0/(1.0 - u_subpix_trim));\nvec3 rgbN \x3d FxaaTexOff(tex, pos.xy, vec2( 0.,-1.), rcpFrame).xyz;\nvec3 rgbW \x3d FxaaTexOff(tex, pos.xy, vec2(-1., 0.), rcpFrame).xyz;\nvec3 rgbM \x3d FxaaTexOff(tex, pos.xy, vec2( 0., 0.), rcpFrame).xyz;\nvec3 rgbE \x3d FxaaTexOff(tex, pos.xy, vec2( 1., 0.), rcpFrame).xyz;\nvec3 rgbS \x3d FxaaTexOff(tex, pos.xy, vec2( 0., 1.), rcpFrame).xyz;\nfloat lumaN \x3d FxaaLuma(rgbN);\nfloat lumaW \x3d FxaaLuma(rgbW);\nfloat lumaM \x3d FxaaLuma(rgbM);\nfloat lumaE \x3d FxaaLuma(rgbE);\nfloat lumaS \x3d FxaaLuma(rgbS);\nfloat rangeMin \x3d min(lumaM, min(min(lumaN, lumaW), min(lumaS, lumaE)));\nfloat rangeMax \x3d max(lumaM, max(max(lumaN, lumaW), max(lumaS, lumaE)));\nfloat range \x3d rangeMax - rangeMin;\nif(range \x3c max(u_edge_threshold_min, rangeMax * u_edge_threshold)) {\nreturn rgbM;\n}\nvec3 rgbL \x3d rgbN + rgbW + rgbM + rgbE + rgbS;\nfloat lumaL \x3d (lumaN + lumaW + lumaE + lumaS) * 0.25;\nfloat rangeL \x3d abs(lumaL - lumaM);\nfloat blendL \x3d max(0.0, (rangeL / range) - u_subpix_trim) * subpix_trim_scale;\nblendL \x3d min(u_subpix_cap, blendL);\nvec3 rgbNW \x3d FxaaTexOff(tex, pos.xy, vec2(-1.,-1.), rcpFrame).xyz;\nvec3 rgbNE \x3d FxaaTexOff(tex, pos.xy, vec2( 1.,-1.), rcpFrame).xyz;\nvec3 rgbSW \x3d FxaaTexOff(tex, pos.xy, vec2(-1., 1.), rcpFrame).xyz;\nvec3 rgbSE \x3d FxaaTexOff(tex, pos.xy, vec2( 1., 1.), rcpFrame).xyz;\nrgbL +\x3d (rgbNW + rgbNE + rgbSW + rgbSE);\nrgbL *\x3d vec3(1.0/9.0);\nfloat lumaNW \x3d FxaaLuma(rgbNW);\nfloat lumaNE \x3d FxaaLuma(rgbNE);\nfloat lumaSW \x3d FxaaLuma(rgbSW);\nfloat lumaSE \x3d FxaaLuma(rgbSE);\nfloat edgeVert \x3d\nabs((0.25 * lumaNW) + (-0.5 * lumaN) + (0.25 * lumaNE)) +\nabs((0.50 * lumaW ) + (-1.0 * lumaM) + (0.50 * lumaE )) +\nabs((0.25 * lumaSW) + (-0.5 * lumaS) + (0.25 * lumaSE));\nfloat edgeHorz \x3d\nabs((0.25 * lumaNW) + (-0.5 * lumaW) + (0.25 * lumaSW)) +\nabs((0.50 * lumaN ) + (-1.0 * lumaM) + (0.50 * lumaS )) +\nabs((0.25 * lumaNE) + (-0.5 * lumaE) + (0.25 * lumaSE));\nbool horzSpan \x3d edgeHorz \x3e\x3d edgeVert;\nfloat lengthSign \x3d horzSpan ? -rcpFrame.y : -rcpFrame.x;\nif(!horzSpan) {\nlumaN \x3d lumaW;\nlumaS \x3d lumaE;\n}\nfloat gradientN \x3d abs(lumaN - lumaM);\nfloat gradientS \x3d abs(lumaS - lumaM);\nlumaN \x3d (lumaN + lumaM) * 0.5;\nlumaS \x3d (lumaS + lumaM) * 0.5;\nif (gradientN \x3c gradientS) {\nlumaN \x3d lumaS;\nlumaN \x3d lumaS;\ngradientN \x3d gradientS;\nlengthSign *\x3d -1.0;\n}\nvec2 posN;\nposN.x \x3d pos.x + (horzSpan ? 0.0 : lengthSign * 0.5);\nposN.y \x3d pos.y + (horzSpan ? lengthSign * 0.5 : 0.0);\ngradientN *\x3d u_search_threshold;\nvec2 posP \x3d posN;\nvec2 offNP \x3d horzSpan ? vec2(rcpFrame.x, 0.0) : vec2(0.0, rcpFrame.y);\nfloat lumaEndN \x3d lumaN;\nfloat lumaEndP \x3d lumaN;\nbool doneN \x3d false;\nbool doneP \x3d false;\nposN +\x3d offNP * vec2(-1.0, -1.0);\nposP +\x3d offNP * vec2( 1.0,  1.0);\nfor(int i \x3d 0; i \x3c fxaaMaxSearchSteps; i++) {\nif(i \x3e\x3d u_search_steps) break;\nif(!doneN) {\nlumaEndN \x3d FxaaLuma(texture2D(tex, posN.xy).xyz);\n}\nif(!doneP) {\nlumaEndP \x3d FxaaLuma(texture2D(tex, posP.xy).xyz);\n}\ndoneN \x3d doneN || (abs(lumaEndN - lumaN) \x3e\x3d gradientN);\ndoneP \x3d doneP || (abs(lumaEndP - lumaN) \x3e\x3d grad
ChemDoodle.lib.mat3,ChemDoodle.lib.mat4,document);
(function(f,q,n,r,e){f.LabelShader=function(){};let k=f._Shader.prototype;f=f.LabelShader.prototype=new f._Shader;f.initUniformLocations=function(b){k.initUniformLocations.call(this,b);this.dimensionUniform=b.getUniformLocation(this.gProgram,"u_dimension")};f.onShaderAttached=function(b){k.onShaderAttached.call(this,b);this.vertexTexCoordAttribute=2;b.bindAttribLocation(this.gProgram,this.vertexTexCoordAttribute,"a_vertex_texcoord")};f.loadDefaultVertexShader=function(b){return this.getShaderFromStr(b,
b.VERTEX_SHADER,"precision mediump float;attribute vec3 a_vertex_position;attribute vec3 a_vertex_normal;attribute vec2 a_vertex_texcoord;uniform mat4 u_model_view_matrix;uniform mat4 u_projection_matrix;uniform vec2 u_dimension;varying vec2 v_texcoord;void main() {gl_Position \x3d u_model_view_matrix * vec4(a_vertex_position, 1.);vec4 depth_pos \x3d vec4(gl_Position);depth_pos.z +\x3d a_vertex_normal.z;gl_Position \x3d u_projection_matrix * gl_Position;depth_pos \x3d u_projection_matrix * depth_pos;gl_Position /\x3d gl_Position.w;gl_Position.xy +\x3d a_vertex_normal.xy / u_dimension * 2.;gl_Position.z \x3d depth_pos.z / depth_pos.w;v_texcoord \x3d a_vertex_texcoord;}")};
f.loadDefaultFragmentShader=function(b){let d=[b.depthTextureExt?"#define CWC_DEPTH_TEX\n":"","precision mediump float;uniform sampler2D u_image;varying vec2 v_texcoord;void main(void) {gl_FragColor \x3d texture2D(u_image, v_texcoord);}"].join("");return this.getShaderFromStr(b,b.FRAGMENT_SHADER,d)};f.enableAttribsArray=function(b){k.enableAttribsArray.call(this,b);b.enableVertexAttribArray(this.vertexNormalAttribute);b.enableVertexAttribArray(this.vertexTexCoordAttribute)};f.disableAttribsArray=
function(b){k.disableAttribsArray.call(this,b);b.disableVertexAttribArray(this.vertexNormalAttribute);b.disableVertexAttribArray(this.vertexTexCoordAttribute)};f.setDimension=function(b,d,e){b.uniform2f(this.dimensionUniform,d,e)}})(ChemDoodle.structures.d3,ChemDoodle.lib.mat3,ChemDoodle.lib.mat4,document);
(function(f,q,n,r,e){f.LightingShader=function(){};let k=f._Shader.prototype;f=f.LightingShader.prototype=new f._Shader;f.initUniformLocations=function(b){k.initUniformLocations.call(this,b);this.positionSampleUniform=b.getUniformLocation(this.gProgram,"u_position_sample");this.colorSampleUniform=b.getUniformLocation(this.gProgram,"u_color_sample");this.ssaoSampleUniform=b.getUniformLocation(this.gProgram,"u_ssao_sample");this.outlineSampleUniform=b.getUniformLocation(this.gProgram,"u_outline_sample")};
f.loadDefaultVertexShader=function(b){return this.getShaderFromStr(b,b.VERTEX_SHADER,"precision mediump float;attribute vec3 a_vertex_position;varying vec2 v_texcoord;void main() {gl_Position \x3d vec4(a_vertex_position, 1.);v_texcoord \x3d a_vertex_position.xy * .5 + .5;}")};f.loadDefaultFragmentShader=function(b){return this.getShaderFromStr(b,b.FRAGMENT_SHADER,"precision mediump float;uniform sampler2D u_position_sample;uniform sampler2D u_color_sample;uniform sampler2D u_ssao_sample;uniform sampler2D u_outline_sample;varying vec2 v_texcoord;void main() {vec4 position \x3d texture2D(u_position_sample, v_texcoord);vec4 color \x3d texture2D(u_color_sample, v_texcoord);vec4 ao \x3d texture2D(u_ssao_sample, v_texcoord);float outline \x3d texture2D(u_outline_sample, v_texcoord).r;if(position.w \x3d\x3d 0. \x26\x26 outline \x3d\x3d 1.) {return;}gl_FragColor \x3d vec4(color.rgb * ao.r * outline, 1.);}")}})(ChemDoodle.structures.d3,
ChemDoodle.lib.mat3,ChemDoodle.lib.mat4,document);
(function(f,q,n,r,e){f.NormalShader=function(){};let k=f._Shader.prototype;f=f.NormalShader.prototype=new f._Shader;f.initUniformLocations=function(b){k.initUniformLocations.call(this,b);this.normalMatrixUniform=b.getUniformLocation(this.gProgram,"u_normal_matrix")};f.loadDefaultVertexShader=function(b){return this.getShaderFromStr(b,b.VERTEX_SHADER,"precision mediump float;attribute vec3 a_vertex_position;attribute vec3 a_vertex_normal;uniform mat4 u_model_view_matrix;uniform mat4 u_projection_matrix;uniform mat3 u_normal_matrix;varying vec3 v_normal;void main() {v_normal \x3d length(a_vertex_normal)\x3d\x3d0. ? a_vertex_normal : u_normal_matrix * a_vertex_normal;gl_Position \x3d u_projection_matrix * u_model_view_matrix * vec4(a_vertex_position, 1.);}")};f.loadDefaultFragmentShader=
function(b){return this.getShaderFromStr(b,b.FRAGMENT_SHADER,"precision mediump float;varying vec3 v_normal;void main(void) {vec3 normal \x3d length(v_normal)\x3d\x3d0. ? vec3(0., 0., 1.) : normalize(v_normal);gl_FragColor \x3d vec4(normal, 0.);}")};f.enableAttribsArray=function(b){k.enableAttribsArray.call(this,b);b.enableVertexAttribArray(this.vertexNormalAttribute)};f.disableAttribsArray=function(b){k.disableAttribsArray.call(this,b);b.disableVertexAttribArray(this.vertexNormalAttribute)};f.setModelViewMatrix=
function(b,d){k.setModelViewMatrix.call(this,b,d);d=q.transpose(n.toInverseMat3(d,[]));b.uniformMatrix3fv(this.normalMatrixUniform,!1,d)}})(ChemDoodle.structures.d3,ChemDoodle.lib.mat3,ChemDoodle.lib.mat4,document);
(function(f,q,n,r,e){f.OutlineShader=function(){};let k=f._Shader.prototype;f=f.OutlineShader.prototype=new f._Shader;f.initUniformLocations=function(b){k.initUniformLocations.call(this,b);this.normalSampleUniform=b.getUniformLocation(this.gProgram,"u_normal_sample");this.depthSampleUniform=b.getUniformLocation(this.gProgram,"u_depth_sample");this.gbufferTextureSizeUniform=b.getUniformLocation(this.gProgram,"u_gbuffer_texture_size");this.normalThresholdUniform=b.getUniformLocation(this.gProgram,"u_normal_threshold");
this.depthThresholdUniform=b.getUniformLocation(this.gProgram,"u_depth_threshold");this.thicknessUniform=b.getUniformLocation(this.gProgram,"u_thickness")};f.loadDefaultVertexShader=function(b){return this.getShaderFromStr(b,b.VERTEX_SHADER,"precision mediump float;attribute vec3 a_vertex_position;varying vec2 v_texcoord;void main() {gl_Position \x3d vec4(a_vertex_position, 1.);v_texcoord \x3d a_vertex_position.xy * .5 + .5;}")};f.loadDefaultFragmentShader=function(b){return this.getShaderFromStr(b,
b.FRAGMENT_SHADER,"precision mediump float;uniform sampler2D u_normal_sample;uniform sampler2D u_depth_sample;uniform float u_normal_threshold;uniform float u_depth_threshold;uniform float u_thickness;uniform vec2 u_gbuffer_texture_size;varying vec2 v_texcoord;void main() {vec3 normal \x3d texture2D(u_normal_sample, v_texcoord).xyz;float depth \x3d texture2D(u_depth_sample, v_texcoord).r;vec2 texelSize \x3d u_thickness/u_gbuffer_texture_size * .5;vec2 offsets[8];offsets[0] \x3d vec2(-texelSize.x, -texelSize.y);offsets[1] \x3d vec2(-texelSize.x, 0);offsets[2] \x3d vec2(-texelSize.x, texelSize.y);offsets[3] \x3d vec2(0, -texelSize.y);offsets[4] \x3d vec2(0,  texelSize.y);offsets[5] \x3d vec2(texelSize.x, -texelSize.y);offsets[6] \x3d vec2(texelSize.x, 0);offsets[7] \x3d vec2(texelSize.x, texelSize.y);float edge \x3d 0.;for (int i \x3d 0; i \x3c 8; i++) {vec3 sampleNorm \x3d texture2D(u_normal_sample, v_texcoord + offsets[i]).xyz;if(normal \x3d\x3d vec3(.0, .0, .0)) {if(sampleNorm !\x3d vec3(.0, .0, .0)) {edge \x3d 1.0;break;}continue;}if (dot(sampleNorm, normal) \x3c u_normal_threshold) {edge \x3d 1.0;break;}float sampleDepth \x3d texture2D(u_depth_sample, v_texcoord + offsets[i]).r;if (abs(sampleDepth - depth) \x3e u_depth_threshold) {edge \x3d 1.0;break;}}edge \x3d 1. - edge;gl_FragColor \x3d vec4(edge, edge, edge, 1.);}")};
f.setGbufferTextureSize=function(b,d,e){b.uniform2f(this.gbufferTextureSizeUniform,d,e)};f.setNormalThreshold=function(b,d){b.uniform1f(this.normalThresholdUniform,d)};f.setDepthThreshold=function(b,d){b.uniform1f(this.depthThresholdUniform,d)};f.setThickness=function(b,d){b.uniform1f(this.thicknessUniform,d)}})(ChemDoodle.structures.d3,ChemDoodle.lib.mat3,ChemDoodle.lib.mat4,document);
(function(f,q,n,r,e){f.PhongShader=function(){};let k=f._Shader.prototype;f=f.PhongShader.prototype=new f._Shader;f.initUniformLocations=function(b){k.initUniformLocations.call(this,b);this.shadowUniform=b.getUniformLocation(this.gProgram,"u_shadow");this.flatColorUniform=b.getUniformLocation(this.gProgram,"u_flat_color");this.normalMatrixUniform=b.getUniformLocation(this.gProgram,"u_normal_matrix");this.lightModelViewMatrixUniform=b.getUniformLocation(this.gProgram,"u_light_model_view_matrix");this.lightProjectionMatrixUniform=
b.getUniformLocation(this.gProgram,"u_light_projection_matrix");this.lightDiffuseColorUniform=b.getUniformLocation(this.gProgram,"u_light_diffuse_color");this.lightSpecularColorUniform=b.getUniformLocation(this.gProgram,"u_light_specular_color");this.lightDirectionUniform=b.getUniformLocation(this.gProgram,"u_light_direction");this.materialAmbientColorUniform=b.getUniformLocation(this.gProgram,"u_material_ambient_color");this.materialDiffuseColorUniform=b.getUniformLocation(this.gProgram,"u_material_diffuse_color");
this.materialSpecularColorUniform=b.getUniformLocation(this.gProgram,"u_material_specular_color");this.materialShininessUniform=b.getUniformLocation(this.gProgram,"u_material_shininess");this.materialAlphaUniform=b.getUniformLocation(this.gProgram,"u_material_alpha");this.fogModeUniform=b.getUniformLocation(this.gProgram,"u_fog_mode");this.fogColorUniform=b.getUniformLocation(this.gProgram,"u_fog_color");this.fogStartUniform=b.getUniformLocation(this.gProgram,"u_fog_start");this.fogEndUniform=b.getUniformLocation(this.gProgram,
"u_fog_end");this.fogDensityUniform=b.getUniformLocation(this.gProgram,"u_fog_density");this.shadowDepthSampleUniform=b.getUniformLocation(this.gProgram,"u_shadow_depth_sample");this.shadowTextureSizeUniform=b.getUniformLocation(this.gProgram,"u_shadow_texture_size");this.shadowIntensityUniform=b.getUniformLocation(this.gProgram,"u_shadow_intensity");this.gammaCorrectionUniform=b.getUniformLocation(this.gProgram,"u_gamma_inverted");this.pointSizeUniform=b.getUniformLocation(this.gProgram,"u_point_size")};
f.loadDefaultVertexShader=function(b){return this.getShaderFromStr(b,b.VERTEX_SHADER,"precision mediump float;attribute vec3 a_vertex_position;attribute vec3 a_vertex_normal;uniform vec3 u_light_diffuse_color;uniform vec3 u_material_ambient_color;uniform vec3 u_material_diffuse_color;uniform mat4 u_model_view_matrix;uniform mat4 u_projection_matrix;uniform mat3 u_normal_matrix;uniform mat4 u_light_model_view_matrix;uniform mat4 u_light_projection_matrix;uniform bool u_shadow;varying vec3 v_viewpos;varying vec4 v_shadcoord;varying vec3 v_diffuse;varying vec3 v_ambient;varying vec3 v_normal;uniform float u_point_size;void main() {v_normal \x3d length(a_vertex_normal)\x3d\x3d0. ? a_vertex_normal : u_normal_matrix * a_vertex_normal;v_ambient \x3d u_material_ambient_color;v_diffuse \x3d u_material_diffuse_color * u_light_diffuse_color;if(u_shadow) {v_shadcoord \x3d u_light_projection_matrix * u_light_model_view_matrix * vec4(a_vertex_position, 1.);v_shadcoord /\x3d v_shadcoord.w;}vec4 viewPos \x3d u_model_view_matrix * vec4(a_vertex_position, 1.);v_viewpos \x3d viewPos.xyz / viewPos.w;gl_Position \x3d u_projection_matrix * viewPos;gl_Position /\x3d gl_Position.w;gl_PointSize \x3d u_point_size;}")};
f.loadDefaultFragmentShader=function(b){let d=[b.depthTextureExt?"#define CWC_DEPTH_TEX\n":"","precision mediump float;uniform vec3 u_light_specular_color;uniform vec3 u_light_direction;uniform vec3 u_material_specular_color;uniform float u_material_shininess;uniform float u_material_alpha;uniform int u_fog_mode;uniform vec3 u_fog_color;uniform float u_fog_density;uniform float u_fog_start;uniform float u_fog_end;uniform bool u_shadow;uniform float u_shadow_intensity;uniform bool u_flat_color;uniform float u_gamma_inverted;uniform sampler2D u_shadow_depth_sample;uniform vec2 u_shadow_texture_size;varying vec3 v_viewpos;varying vec4 v_shadcoord;varying vec3 v_diffuse;varying vec3 v_ambient;varying vec3 v_normal;\n#ifndef CWC_DEPTH_TEX\nfloat unpack (vec4 colour) {const vec4 bitShifts \x3d vec4(1.,1. / 255.,1. / (255. * 255.),1. / (255. * 255. * 255.));return dot(colour, bitShifts);}\n#endif\nfloat shadowMapDepth(vec4 shadowMapColor) {float zShadowMap;\n#ifdef CWC_DEPTH_TEX\nzShadowMap \x3d shadowMapColor.r;\n#else\nzShadowMap \x3d unpack(shadowMapColor);\n#endif\nreturn zShadowMap;}void main(void) {vec3 color \x3d v_diffuse;if(length(v_normal)!\x3d0.){vec3 normal \x3d normalize(v_normal);vec3 lightDir \x3d normalize(-u_light_direction);float nDotL \x3d dot(normal, lightDir);float shadow \x3d 0.0;if(u_shadow) {vec3 depthCoord \x3d .5 + v_shadcoord.xyz / v_shadcoord.w * .5;if(depthCoord.z \x3c\x3d 1. \x26\x26 depthCoord.z \x3e\x3d 0.) {float bias \x3d max(.05 * (1. - nDotL), .005);vec2 texelSize \x3d 1. / u_shadow_texture_size;for(int x \x3d -1; x \x3c\x3d 1; ++x) {for(int y \x3d -1; y \x3c\x3d 1; ++y)  {vec4 shadowMapColor \x3d texture2D(u_shadow_depth_sample, depthCoord.xy + vec2(x, y) * texelSize);float zShadowMap \x3d shadowMapDepth(shadowMapColor);shadow +\x3d zShadowMap + bias \x3c depthCoord.z ? 1. : 0.;}}shadow /\x3d 9.;shadow *\x3d u_shadow_intensity;}}if(!u_flat_color) {vec3 viewDir \x3d normalize(-v_viewpos);vec3 halfDir \x3d normalize(lightDir + viewDir);float nDotHV \x3d max(dot(halfDir, normal), 0.);vec3 specular \x3d u_material_specular_color * u_light_specular_color;color*\x3dmax(nDotL, 0.);color+\x3dspecular * pow(nDotHV, u_material_shininess);}color \x3d (1.-shadow)*color+v_ambient;}gl_FragColor \x3d vec4(pow(color, vec3(u_gamma_inverted)), u_material_alpha);if(u_fog_mode !\x3d 0){float fogCoord \x3d 1.-clamp((u_fog_end - gl_FragCoord.z/gl_FragCoord.w) / (u_fog_end - u_fog_start), 0., 1.);float fogFactor \x3d 1.;if(u_fog_mode \x3d\x3d 1){fogFactor \x3d 1.-fogCoord;}else if(u_fog_mode \x3d\x3d 2) {fogFactor \x3d clamp(exp(-u_fog_density*fogCoord), 0., 1.);}else if(u_fog_mode \x3d\x3d 3) {fogFactor \x3d clamp(exp(-pow(u_fog_density*fogCoord, 2.)), 0., 1.);}gl_FragColor \x3d mix(vec4(u_fog_color, 1.), gl_FragColor, fogFactor);}}"].join("");
return this.getShaderFromStr(b,b.FRAGMENT_SHADER,d)};f.enableAttribsArray=function(b){k.enableAttribsArray.call(this,b);b.enableVertexAttribArray(this.vertexNormalAttribute)};f.disableAttribsArray=function(b){k.disableAttribsArray.call(this,b);b.disableVertexAttribArray(this.vertexNormalAttribute)};f.setMatrixUniforms=function(b,d){if(d===e)this.setModelViewMatrix(b,b.modelViewMatrix),this.setLightModelViewMatrix(b,b.lightViewMatrix);else{let e=n.multiply(b.modelViewMatrix,d,[]);d=n.multiply(b.lightViewMatrix,
d,[]);this.setModelViewMatrix(b,e);this.setLightModelViewMatrix(b,d)}};f.setModelViewMatrix=function(b,d){k.setModelViewMatrix.call(this,b,d);d=q.transpose(n.toInverseMat3(d,[]));b.uniformMatrix3fv(this.normalMatrixUniform,!1,d)};f.setFlatColor=function(b,d){b.uniform1i(this.flatColorUniform,d)};f.setShadow=function(b,d){b.uniform1i(this.shadowUniform,d)};f.setFogMode=function(b,d){b.uniform1i(this.fogModeUniform,d)};f.setFogColor=function(b,d){b.uniform3fv(this.fogColorUniform,d)};f.setFogStart=
function(b,d){b.uniform1f(this.fogStartUniform,d)};f.setFogEnd=function(b,d){b.uniform1f(this.fogEndUniform,d)};f.setFogDensity=function(b,d){b.uniform1f(this.fogDensityUniform,d)};f.setMaterialAmbientColor=function(b,d){b.uniform3fv(this.materialAmbientColorUniform,d)};f.setMaterialDiffuseColor=function(b,d){b.uniform3fv(this.materialDiffuseColorUniform,d)};f.setMaterialSpecularColor=function(b,d){b.uniform3fv(this.materialSpecularColorUniform,d)};f.setMaterialShininess=function(b,d){b.uniform1f(this.materialShininessUniform,
d)};f.setMaterialAlpha=function(b,d){b.uniform1f(this.materialAlphaUniform,d)};f.setLightDiffuseColor=function(b,d){b.uniform3fv(this.lightDiffuseColorUniform,d)};f.setLightSpecularColor=function(b,d){b.uniform3fv(this.lightSpecularColorUniform,d)};f.setLightDirection=function(b,d){b.uniform3fv(this.lightDirectionUniform,d)};f.setLightModelViewMatrix=function(b,d){b.uniformMatrix4fv(this.lightModelViewMatrixUniform,!1,d)};f.setLightProjectionMatrix=function(b,d){b.uniformMatrix4fv(this.lightProjectionMatrixUniform,
!1,d)};f.setShadowTextureSize=function(b,d,e){b.uniform2f(this.shadowTextureSizeUniform,d,e)};f.setShadowIntensity=function(b,d){b.uniform1f(this.shadowIntensityUniform,d)};f.setGammaCorrection=function(b,d){b.uniform1f(this.gammaCorrectionUniform,1/d)};f.setPointSize=function(b,d){b.uniform1f(this.pointSizeUniform,d)}})(ChemDoodle.structures.d3,ChemDoodle.lib.mat3,ChemDoodle.lib.mat4,document);
(function(f,q,n,r,e){f.PickShader=function(){};let k=f._Shader.prototype;f=f.PickShader.prototype=new f._Shader;f.initUniformLocations=function(b){k.initUniformLocations.call(this,b);this.materialDiffuseColorUniform=b.getUniformLocation(this.gProgram,"u_material_diffuse_color")};f.loadDefaultVertexShader=function(b){return this.getShaderFromStr(b,b.VERTEX_SHADER,"precision mediump float;attribute vec3 a_vertex_position;uniform mat4 u_model_view_matrix;uniform mat4 u_projection_matrix;void main() {gl_Position \x3d u_projection_matrix * u_model_view_matrix * vec4(a_vertex_position, 1.);gl_Position /\x3d gl_Position.w;}")};
f.loadDefaultFragmentShader=function(b){let d=[b.depthTextureExt?"#define CWC_DEPTH_TEX\n":"","precision mediump float;uniform vec3 u_material_diffuse_color;void main(void) {gl_FragColor \x3d vec4(u_material_diffuse_color, 1.);}"].join("");return this.getShaderFromStr(b,b.FRAGMENT_SHADER,d)};f.setMaterialDiffuseColor=function(b,d){b.uniform3fv(this.materialDiffuseColorUniform,d)}})(ChemDoodle.structures.d3,ChemDoodle.lib.mat3,ChemDoodle.lib.mat4,document);
(function(f,q,n,r,e){f.PositionShader=function(){};f=f.PositionShader.prototype=new f._Shader;f.loadDefaultVertexShader=function(e){return this.getShaderFromStr(e,e.VERTEX_SHADER,"precision mediump float;attribute vec3 a_vertex_position;uniform mat4 u_model_view_matrix;uniform mat4 u_projection_matrix;varying vec4 v_position;void main() {vec4 viewPos \x3d u_model_view_matrix * vec4(a_vertex_position, 1.);gl_Position \x3d u_projection_matrix * viewPos;v_position \x3d viewPos / viewPos.w;}")};f.loadDefaultFragmentShader=
function(e){return this.getShaderFromStr(e,e.FRAGMENT_SHADER,"precision mediump float;varying vec4 v_position;void main(void) {gl_FragColor \x3d v_position;}")}})(ChemDoodle.structures.d3,ChemDoodle.lib.mat3,ChemDoodle.lib.mat4,document);
(function(f,q,n,r,e){f.QuadShader=function(){};f=f.QuadShader.prototype=new f._Shader;f.loadDefaultVertexShader=function(e){return this.getShaderFromStr(e,e.VERTEX_SHADER,"precision mediump float;attribute vec3 a_vertex_position;varying vec2 v_texcoord;void main() {gl_Position \x3d vec4(a_vertex_position, 1.);v_texcoord \x3d a_vertex_position.xy * .5 + .5;}")};f.loadDefaultFragmentShader=function(e){return this.getShaderFromStr(e,e.FRAGMENT_SHADER,"precision mediump float;uniform sampler2D u_image;varying vec2 v_texcoord;void main() {gl_FragColor \x3d texture2D(u_image, v_texcoord);}")}})(ChemDoodle.structures.d3,
ChemDoodle.lib.mat3,ChemDoodle.lib.mat4,document);
(function(f,q,n,r,e,k,b){function d(a,b,d,e,h,n){d=a[0]*n+d-n;e=a[1]*n+e-n;a=a[2]*n+h-n;h=-1;for(let g=0,f=b.length;g<f;g++)if(n=b[g],.001>k.abs(n.x-d)&&.001>k.abs(n.y-e)&&.001>k.abs(n.z-a)){h=g;break}-1==h&&(h=b.length,b.push(new f.Atom("C",d,e,a)));return h}let h=function(a,b,d){this.i1=a;this.i2=b;this.i3=d};q._Surface=function(){};q=q._Surface.prototype=new q._Mesh;q.generate=function(a,b,d,e,f,h,k,n){a=[];b=f[4]-e;for(d=0;d<n;d++){let d=f[2]-e;for(let g=0;g<k;g++){let c=f[0]-e;for(let g=0;g<
h;g++)a.push(this.calculate(c,d,b)),c+=e;d+=e}b+=e}return a};q.build=function(a,b,l){let g=[],m=[],n=[];var u=[Infinity,-Infinity,Infinity,-Infinity,Infinity,-Infinity];b+=2;for(let c=0,d=a.length;c<d;c++){var w=a[c];u[0]=k.min(u[0],w.x-b);u[1]=k.max(u[1],w.x+b);u[2]=k.min(u[2],w.y-b);u[3]=k.max(u[3],w.y+b);u[4]=k.min(u[4],w.z-b);u[5]=k.max(u[5],w.z+b)}a=u;b=a[1]-a[0];w=a[3]-a[2];var q=a[5]-a[4];u=k.min(b,k.min(w,q))/l;l=2+k.ceil(b/u);var y=2+k.ceil(w/u),c=2+k.ceil(q/u);b=this.generate(b,w,q,u,a,
l,y,c);b=r(b,[l,y,c]);l=[];w=[];for(let c=0,e=b.vertices.length;c<e;c++)w.push(d(b.vertices[c],l,a[0],a[2],a[4],u));a=[];for(let c=0,d=b.faces.length;c<d;c++)y=b.faces[c],u=w[y[0]],q=w[y[1]],y=w[y[2]],a.push(new h(u,q,y)),n.push(u,q,y);u=[];for(let c=0,d=l.length;c<d;c++){b=[];for(let d=0,e=a.length;d<e;d++)if(w=a[d],w.i1===c||w.i2===c||w.i3===c)w.i1!=c&&-1===b.indexOf(w.i1)&&b.push(w.i1),w.i2!=c&&-1===b.indexOf(w.i2)&&b.push(w.i2),w.i3!=c&&-1===b.indexOf(w.i3)&&b.push(w.i3);u.push(b)}b=[];for(let a=
0,d=l.length;a<d;a++){q=l[a];y=u[a];w=new f.Atom;if(3>y.length)w.x=q.x,w.y=q.y,w.z=q.z;else{c=1;5>y.length&&(c=.5);for(let a=0,b=y.length;a<b;a++){let b=l[y[a]];w.x+=b.x;w.y+=b.y;w.z+=b.z}w.x+=q.x*c;w.y+=q.y*c;w.z+=q.z*c;q=1/(c+y.length);w.x*=q;w.y*=q;w.z*=q}b.push(w)}l=b;for(let a=0,b=l.length;a<b;a++)u=l[a],g.push(u.x,u.y,u.z);for(let c=0,d=a.length;c<d;c++)u=a[c],b=l[u.i1],q=l[u.i2],w=l[u.i3],q=[q.x-b.x,q.y-b.y,q.z-b.z],e.cross(q,[w.x-b.x,w.y-b.y,w.z-b.z]),isNaN(q[0])&&(q=[0,0,0]),u.normal=q;for(let b=
0,c=l.length;b<c;b++){l=[0,0,0];for(let c=0,d=a.length;c<d;c++)if(u=a[c],u.i1===b||u.i2===b||u.i3===b)l[0]+=u.normal[0],l[1]+=u.normal[1],l[2]+=u.normal[2];e.normalize(l);m.push(l[0],l[1],l[2])}this.storeData(g,m,n)};q.render=function(a,b){this.styles&&(b=this.styles);b.surfaces_display&&(a.shader.setMatrixUniforms(a),this.bindBuffers(a),a.material.setTempColors(a,b.surfaces_materialAmbientColor_3D,b.surfaces_color,b.surfaces_materialSpecularColor_3D,b.surfaces_materialShininess_3D),a.material.setAlpha(a,
b.surfaces_alpha),"Dots"===b.surfaces_style?(a.shader.setPointSize(a,b.shapes_pointSize),a.drawElements(a.POINTS,this.vertexIndexBuffer.numItems,a.UNSIGNED_SHORT,0)):"Mesh"===b.surfaces_style?(a.lineWidth(b.shapes_lineWidth),a.drawElements(a.LINES,this.vertexIndexBuffer.numItems,a.UNSIGNED_SHORT,0)):a.drawElements(a.TRIANGLES,this.vertexIndexBuffer.numItems,a.UNSIGNED_SHORT,0))}})(ChemDoodle.structures,ChemDoodle.structures.d3,ChemDoodle.ELEMENT,ChemDoodle.lib.MarchingCubes,ChemDoodle.lib.vec3,Math);
(function(f,q,n,r,e){q.SASSurface=function(e,b,d){this.atoms=e;this.probeRadius=b;this.resolution=d;this.build(e,b,d)};(q.SASSurface.prototype=new q._Surface).calculate=function(e,b,d){let h=Infinity;e=new f.Atom("C",e,b,d);for(let a=0,g=this.atoms.length;a<g;a++)b=this.atoms[a],d=n[b.label]&&0!==n[b.label].vdWRadius?n[b.label].vdWRadius:2,b=b.distance3D(e)-this.probeRadius-d,h=r.min(h,b);return h}})(ChemDoodle.structures,ChemDoodle.structures.d3,ChemDoodle.ELEMENT,Math);
(function(f,q,n,r,e){q.VDWSurface=function(e,b){this.atoms=e;this.probeRadius=0;this.resolution=b;this.build(e,0,b)};(q.VDWSurface.prototype=new q._Surface).calculate=function(e,b,d){let h=Infinity;e=new f.Atom("C",e,b,d);for(let a=0,g=this.atoms.length;a<g;a++)b=this.atoms[a],d=n[b.label]&&0!==n[b.label].vdWRadius?n[b.label].vdWRadius:2,b=b.distance3D(e)-d,h=r.min(h,b);return h}})(ChemDoodle.structures,ChemDoodle.structures.d3,ChemDoodle.ELEMENT,Math);
(function(f,q,n,r){f.Plate=function(e){this.lanes=Array(e);i=0;for(ii=e;i<ii;i++)this.lanes[i]=[]};r=f.Plate.prototype;r.sort=function(){i=0;for(ii=this.lanes.length;i<ii;i++)this.lanes[i].sort(function(e,f){return e-f})};r.draw=function(e,f){f=e.canvas.width;var b=e.canvas.height;this.origin=9*b/10;this.front=b/10;this.laneLength=this.origin-this.front;e.strokeStyle="#000000";e.beginPath();e.moveTo(0,this.front);e.lineTo(f,this.front);e.setLineDash([3]);e.stroke();e.setLineDash([]);e.beginPath();
e.moveTo(0,this.origin);e.lineTo(f,this.origin);e.closePath();e.stroke();i=0;for(ii=this.lanes.length;i<ii;i++)for(b=(i+1)*f/(ii+1),e.beginPath(),e.moveTo(b,this.origin),e.lineTo(b,this.origin+3),e.closePath(),e.stroke(),s=0,ss=this.lanes[i].length;s<ss;s++){let d=this.origin-this.laneLength*this.lanes[i][s].rf;switch(this.lanes[i][s].type){case "compact":e.beginPath();e.arc(b,d,3,0,2*n.PI,!1);e.closePath();break;case "expanded":e.beginPath();e.arc(b,d,7,0,2*n.PI,!1);e.closePath();break;case "widened":q.contextEllipse(e,
b-18,d-10,36,10);break;case "cresent":e.beginPath(),e.arc(b,d,9,0,n.PI,!0),e.closePath()}switch(this.lanes[i][s].style){case "solid":e.fillStyle="#000000";e.fill();break;case "transparent":e.stroke()}}};f.Plate.Spot=function(e,f,b){this.type=e;this.rf=f;this.style=b?b:"solid"}})(ChemDoodle.structures,ChemDoodle.extensions,Math);
(function(f,q,n,r,e,k){f.DEFAULT_STYLES={backgroundColor:"#FFFFFF",scale:1,rotateAngle:0,bondLength_2D:20,angstromsPerBondLength:1.25,lightDirection_3D:[-.1,-.1,-1],lightDiffuseColor_3D:"#FFFFFF",lightSpecularColor_3D:"#FFFFFF",projectionPerspective_3D:!0,projectionPerspectiveVerticalFieldOfView_3D:45,projectionOrthoWidth_3D:40,projectionWidthHeightRatio_3D:k,projectionFrontCulling_3D:.1,projectionBackCulling_3D:1E4,cullBackFace_3D:!0,fog_mode_3D:0,fog_color_3D:"#000000",fog_start_3D:0,fog_end_3D:1,
fog_density_3D:1,shadow_3D:!1,shadow_intensity_3D:.85,flat_color_3D:!1,antialias_3D:!0,gammaCorrection_3D:2.2,colorHover:"#885110",colorSelect:"#0060B2",colorError:"#c10000",colorPreview:"#00FF00",ssao_3D:!1,ssao_kernel_radius:17,ssao_kernel_samples:32,ssao_power:1,outline_3D:!1,outline_thickness:1,outline_normal_threshold:.85,outline_depth_threshold:.1,fxaa_edgeThreshold:.0625,fxaa_edgeThresholdMin:1/12,fxaa_searchSteps:64,fxaa_searchThreshold:.25,fxaa_subpixCap:1,fxaa_subpixTrim:0,atoms_display:!0,
atoms_color:"#000000",atoms_font_size_2D:12,atoms_font_families_2D:["Helvetica","Arial","Dialog"],atoms_font_bold_2D:!1,atoms_font_italic_2D:!1,atoms_circles_2D:!1,atoms_circleDiameter_2D:10,atoms_circleBorderWidth_2D:1,atoms_lonePairDistance_2D:8,atoms_lonePairSpread_2D:4,atoms_lonePairDiameter_2D:1,atoms_useJMOLColors:!1,atoms_usePYMOLColors:!1,atoms_HBlack_2D:!0,atoms_implicitHydrogens_2D:!0,atoms_displayTerminalCarbonLabels_2D:!1,atoms_showHiddenCarbons_2D:!0,atoms_showAttributedCarbons_2D:!0,
atoms_displayAllCarbonLabels_2D:!1,atoms_resolution_3D:30,atoms_sphereDiameter_3D:.8,atoms_useVDWDiameters_3D:!1,atoms_vdwMultiplier_3D:1,atoms_materialAmbientColor_3D:"#000000",atoms_materialSpecularColor_3D:"#555555",atoms_materialShininess_3D:32,atoms_nonBondedAsStars_3D:!1,atoms_displayLabels_3D:!1,bonds_display:!0,bonds_color:"#000000",bonds_width_2D:1,bonds_useAbsoluteSaturationWidths_2D:!0,bonds_saturationWidth_2D:.2,bonds_saturationWidthAbs_2D:5,bonds_ends_2D:"round",bonds_splitColor:!1,bonds_colorGradient:!1,
bonds_saturationAngle_2D:n.PI/3,bonds_symmetrical_2D:!1,bonds_clearOverlaps_2D:!1,bonds_overlapClearWidth_2D:.5,bonds_atomLabelBuffer_2D:1,bonds_wedgeThickness_2D:6,bonds_wavyLength_2D:4,bonds_hashWidth_2D:1,bonds_hashSpacing_2D:2.5,bonds_dotSize_2D:2,bonds_lewisStyle_2D:!1,bonds_showBondOrders_3D:!1,bonds_resolution_3D:30,bonds_renderAsLines_3D:!1,bonds_cylinderDiameter_3D:.3,bonds_pillLatitudeResolution_3D:10,bonds_pillLongitudeResolution_3D:20,bonds_pillHeight_3D:.3,bonds_pillSpacing_3D:.1,bonds_pillDiameter_3D:.3,
bonds_materialAmbientColor_3D:"#000000",bonds_materialSpecularColor_3D:"#555555",bonds_materialShininess_3D:32,proteins_displayRibbon:!0,proteins_displayBackbone:!1,proteins_backboneThickness:1.5,proteins_backboneColor:"#CCCCCC",proteins_ribbonCartoonize:!1,proteins_displayPipePlank:!1,proteins_residueColor:"none",proteins_primaryColor:"#FF0D0D",proteins_secondaryColor:"#FFFF30",proteins_ribbonCartoonHelixPrimaryColor:"#00E740",proteins_ribbonCartoonHelixSecondaryColor:"#9905FF",proteins_ribbonCartoonSheetColor:"#E8BB99",
proteins_tubeColor:"#FF0D0D",proteins_tubeResolution_3D:15,proteins_ribbonThickness:.2,proteins_tubeThickness:.5,proteins_plankSheetWidth:3.5,proteins_cylinderHelixDiameter:4,proteins_verticalResolution:8,proteins_horizontalResolution:8,proteins_materialAmbientColor_3D:"#000000",proteins_materialSpecularColor_3D:"#555555",proteins_materialShininess_3D:32,nucleics_display:!0,nucleics_tubeColor:"#CCCCCC",nucleics_baseColor:"#C10000",nucleics_residueColor:"none",nucleics_tubeThickness:1.5,nucleics_tubeResolution_3D:15,
nucleics_verticalResolution:8,nucleics_materialAmbientColor_3D:"#000000",nucleics_materialSpecularColor_3D:"#555555",nucleics_materialShininess_3D:32,macro_displayAtoms:!1,macro_displayBonds:!1,macro_atomToLigandDistance:-1,macro_showWater:!1,macro_colorByChain:!1,macro_rainbowColors:["#0000FF","#00FFFF","#00FF00","#FFFF00","#FF0000"],surfaces_display:!0,surfaces_alpha:.5,surfaces_style:"Solid",surfaces_color:"white",surfaces_materialAmbientColor_3D:"#000000",surfaces_materialSpecularColor_3D:"#000000",
surfaces_materialShininess_3D:32,plots_color:"#000000",plots_width:1,plots_showIntegration:!1,plots_integrationColor:"#c10000",plots_integrationLineWidth:1,plots_showGrid:!1,plots_gridColor:"gray",plots_gridLineWidth:.5,plots_showYAxis:!0,plots_flipXAxis:!1,text_font_size:12,text_font_families:["Helvetica","Arial","Dialog"],text_font_bold:!0,text_font_italic:!1,text_font_stroke_3D:!0,text_color:"#000000",shapes_color:"#000000",shapes_lineWidth:1,shapes_pointSize:2,shapes_arrowLength_2D:8,compass_display:!1,
compass_axisXColor_3D:"#FF0000",compass_axisYColor_3D:"#00FF00",compass_axisZColor_3D:"#0000FF",compass_size_3D:50,compass_resolution_3D:10,compass_displayText_3D:!0,compass_type_3D:0,measurement_update_3D:!1,measurement_angleBands_3D:10,measurement_displayText_3D:!0};q.Styles=function(b){e.assign(this,r.parse(r.stringify(b===k?f.DEFAULT_STYLES:b)))};n=q.Styles.prototype;n.set3DRepresentation=function(b){this.bonds_display=this.atoms_display=!0;this.bonds_color="#777777";this.bonds_showBondOrders_3D=
this.bonds_splitColor=this.atoms_useJMOLColors=this.atoms_useVDWDiameters_3D=!0;this.bonds_renderAsLines_3D=!1;"Ball and Stick"===b?(this.atoms_vdwMultiplier_3D=.3,this.bonds_splitColor=!1,this.bonds_cylinderDiameter_3D=.3,this.bonds_materialAmbientColor_3D=ChemDoodle.DEFAULT_STYLES.atoms_materialAmbientColor_3D,this.bonds_pillDiameter_3D=.15):"van der Waals Spheres"===b?(this.bonds_display=!1,this.atoms_vdwMultiplier_3D=1):"Stick"===b?(this.bonds_showBondOrders_3D=this.atoms_useVDWDiameters_3D=!1,
this.bonds_cylinderDiameter_3D=this.atoms_sphereDiameter_3D=.8,this.bonds_materialAmbientColor_3D=this.atoms_materialAmbientColor_3D):"Wireframe"===b?(this.atoms_useVDWDiameters_3D=!1,this.bonds_cylinderDiameter_3D=this.bonds_pillDiameter_3D=.05,this.atoms_sphereDiameter_3D=.15,this.bonds_materialAmbientColor_3D=ChemDoodle.DEFAULT_STYLES.atoms_materialAmbientColor_3D):"Line"===b?(this.atoms_display=!1,this.bonds_renderAsLines_3D=!0,this.bonds_width_2D=1,this.bonds_cylinderDiameter_3D=.05):alert('"'+
b+'" is not recognized. Use one of the following strings:\n\n1. Ball and Stick\n2. van der Waals Spheres\n3. Stick\n4. Wireframe\n5. Line\n')};n.copy=function(){return new q.Styles(this)}})(ChemDoodle,ChemDoodle.structures,Math,JSON,Object);
(function(f,q,n,r,e){n.getPointsPerAngstrom=function(){return f.DEFAULT_STYLES.bondLength_2D/f.DEFAULT_STYLES.angstromsPerBondLength};n.BondDeducer=function(){};e=n.BondDeducer.prototype;e.margin=1.1;e.deduceCovalentBonds=function(e,b){let d=n.getPointsPerAngstrom();b&&(d=b);for(let f=0,a=e.atoms.length;f<a;f++)for(b=f+1;b<a;b++){let a=e.atoms[f],h=e.atoms[b];a.distance3D(h)<(q[a.label].covalentRadius+q[h.label].covalentRadius)*d*this.margin&&e.bonds.push(new r.Bond(a,h,1))}}})(ChemDoodle,ChemDoodle.ELEMENT,
ChemDoodle.informatics,ChemDoodle.structures);
(function(f,q,n){f.HydrogenDeducer=function(){};f.HydrogenDeducer.prototype.removeHydrogens=function(f,e){let k=[],b=[];for(let d=0,h=f.bonds.length;d<h;d++){let a=f.bonds[d],g="H"!==a.a1.label&&"H"!==a.a2.label;g||e||a.stereo===q.Bond.STEREO_NONE||(g=!0);g?(a.a1.tag=!0,b.push(a)):("H"===a.a1.label&&(a.a1.remove=!0),"H"===a.a2.label&&(a.a2.remove=!0))}for(let b=0,h=f.atoms.length;b<h;b++)e=f.atoms[b],e.remove?e.remove=n:k.push(e);f.atoms=k;f.bonds=b}})(ChemDoodle.informatics,ChemDoodle.structures);
(function(f,q,n){f.Splitter=function(){};f.Splitter.prototype.split=function(f){let e=[];for(let b=0,e=f.atoms.length;b<e;b++)f.atoms[b].visited=!1;for(let b=0,e=f.bonds.length;b<e;b++)f.bonds[b].visited=!1;for(let d=0,h=f.atoms.length;d<h;d++){var k=f.atoms[d];if(!k.visited){let a=new q.Molecule;a.atoms.push(k);k.visited=!0;let d=new q.Queue;for(d.enqueue(k);!d.isEmpty();){k=d.dequeue();for(let e=0,g=f.bonds.length;e<g;e++){var b=f.bonds[e];b.contains(k)&&!b.visited&&(b.visited=!0,a.bonds.push(b),
b=b.getNeighbor(k),b.visited||(b.visited=!0,a.atoms.push(b),d.enqueue(b)))}}e.push(a)}}return e}})(ChemDoodle.informatics,ChemDoodle.structures);(function(f,q,n,r){f.StructureBuilder=function(){};f.StructureBuilder.prototype.copy=function(e){let f=new q.JSONInterpreter;return f.molFrom(f.molTo(e))}})(ChemDoodle.informatics,ChemDoodle.io,ChemDoodle.structures);
(function(f,q){f._Counter=function(){};f=f._Counter.prototype;f.value=0;f.molecule=q;f.setMolecule=function(f){this.value=0;this.molecule=f;this.innerCalculate&&this.innerCalculate()}})(ChemDoodle.informatics);(function(f,q){f.FrerejacqueNumberCounter=function(f){this.setMolecule(f)};(f.FrerejacqueNumberCounter.prototype=new f._Counter).innerCalculate=function(){this.value=this.molecule.bonds.length-this.molecule.atoms.length+(new f.NumberOfMoleculesCounter(this.molecule)).value}})(ChemDoodle.informatics);
(function(f,q,n){q.NumberOfMoleculesCounter=function(f){this.setMolecule(f)};(q.NumberOfMoleculesCounter.prototype=new q._Counter).innerCalculate=function(){for(let e=0,f=this.molecule.atoms.length;e<f;e++)this.molecule.atoms[e].visited=!1;for(let e=0,k=this.molecule.atoms.length;e<k;e++)if(!this.molecule.atoms[e].visited){this.value++;let b=new f.Queue;this.molecule.atoms[e].visited=!0;for(b.enqueue(this.molecule.atoms[e]);!b.isEmpty();){let d=b.dequeue();for(let e=0,a=this.molecule.bonds.length;e<
a;e++){var n=this.molecule.bonds[e];n.contains(d)&&(n=n.getNeighbor(d),n.visited||(n.visited=!0,b.enqueue(n)))}}}}})(ChemDoodle.structures,ChemDoodle.informatics);
(function(f,q){f._RingFinder=function(){};f=f._RingFinder.prototype;f.atoms=q;f.bonds=q;f.rings=q;f.reduce=function(f){for(let e=0,k=f.atoms.length;e<k;e++)f.atoms[e].visited=!1;for(let e=0,k=f.bonds.length;e<k;e++)f.bonds[e].visited=!1;let n=!0;for(;n;){n=!1;for(let e=0,k=f.atoms.length;e<k;e++){let b=0,d;for(let h=0,a=f.bonds.length;h<a;h++)if(f.bonds[h].contains(f.atoms[e])&&!f.bonds[h].visited){b++;if(2===b)break;d=f.bonds[h]}1===b&&(n=!0,d.visited=!0,f.atoms[e].visited=!0)}}for(let e=0,k=f.atoms.length;e<
k;e++)f.atoms[e].visited||this.atoms.push(f.atoms[e]);for(let e=0,k=f.bonds.length;e<k;e++)f.bonds[e].visited||this.bonds.push(f.bonds[e]);0===this.bonds.length&&0!==this.atoms.length&&(this.atoms=[])};f.setMolecule=function(f){this.atoms=[];this.bonds=[];this.rings=[];this.reduce(f);2<this.atoms.length&&this.innerGetRings&&this.innerGetRings()};f.fuse=function(){for(let f=0,r=this.rings.length;f<r;f++)for(let e=0,k=this.bonds.length;e<k;e++)-1!==this.rings[f].atoms.indexOf(this.bonds[e].a1)&&-1!==
this.rings[f].atoms.indexOf(this.bonds[e].a2)&&this.rings[f].bonds.push(this.bonds[e])}})(ChemDoodle.informatics);
(function(f,q,n){function r(e,b){this.atoms=[];if(b)for(let d=0,e=b.atoms.length;d<e;d++)this.atoms[d]=b.atoms[d];this.atoms.push(e)}let e=r.prototype;e.grow=function(e,b){let d=this.atoms[this.atoms.length-1],f=[];for(let a=0,g=e.length;a<g;a++)if(e[a].contains(d)){let g=e[a].getNeighbor(d);-1===b.indexOf(g)&&f.push(g)}e=[];for(let a=0,b=f.length;a<b;a++)e.push(new r(f[a],this));return e};e.check=function(e,b,d){for(let a=0,d=b.atoms.length-1;a<d;a++)if(-1!==this.atoms.indexOf(b.atoms[a]))return n;
let f;if(b.atoms[b.atoms.length-1]===this.atoms[this.atoms.length-1]){f=new q.Ring;f.atoms[0]=d;for(let a=0,b=this.atoms.length;a<b;a++)f.atoms.push(this.atoms[a]);for(e=b.atoms.length-2;0<=e;e--)f.atoms.push(b.atoms[e])}else{let a=[];for(let d=0,f=e.length;d<f;d++)e[d].contains(b.atoms[b.atoms.length-1])&&a.push(e[d]);for(let g=0,h=a.length;g<h;g++)if((1===b.atoms.length||!a[g].contains(b.atoms[b.atoms.length-2]))&&a[g].contains(this.atoms[this.atoms.length-1])){f=new q.Ring;f.atoms[0]=d;for(let a=
0,b=this.atoms.length;a<b;a++)f.atoms.push(this.atoms[a]);for(e=b.atoms.length-1;0<=e;e--)f.atoms.push(b.atoms[e]);break}}return f};f.EulerFacetRingFinder=function(e){this.setMolecule(e)};f=f.EulerFacetRingFinder.prototype=new f._RingFinder;f.fingerBreak=5;f.innerGetRings=function(){for(let g=0,h=this.atoms.length;g<h;g++){let h=[];for(let a=0,b=this.bonds.length;a<b;a++)this.bonds[a].contains(this.atoms[g])&&h.push(this.bonds[a].getNeighbor(this.atoms[g]));for(let m=0,l=h.length;m<l;m++)for(let l=
m+1;l<h.length;l++){var e=[];e[0]=new r(h[m]);e[1]=new r(h[l]);var b=[];b[0]=this.atoms[g];for(let a=0,d=h.length;a<d;a++)a!==m&&a!==l&&b.push(h[a]);var d=[],f=e[0].check(this.bonds,e[1],this.atoms[g]);for(f&&(d[0]=f);0===d.length&&0<e.length&&e[0].atoms.length<this.fingerBreak;){f=[];for(let d=0,g=e.length;d<g;d++){var a=e[d].grow(this.bonds,b);for(let b=0,c=a.length;b<c;b++)f.push(a[b])}e=f;for(let b=0,h=e.length;b<h;b++)for(f=b+1;f<h;f++)(a=e[b].check(this.bonds,e[f],this.atoms[g]))&&d.push(a);
if(0===d.length){f=[];for(let d=0,e=b.length;d<e;d++)for(let e=0,c=this.bonds.length;e<c;e++)this.bonds[e].contains(b[d])&&(a=this.bonds[e].getNeighbor(b[d]),-1===b.indexOf(a)&&-1===f.indexOf(a)&&f.push(a));for(let a=0,d=f.length;a<d;a++)b.push(f[a])}}if(0<d.length){e=n;for(let a=0,b=d.length;a<b;a++)if(!e||e.atoms.length>d[a].atoms.length)e=d[a];d=!1;for(let a=0,f=this.rings.length;a<f;a++){b=!0;for(let d=0,c=e.atoms.length;d<c;d++)if(-1===this.rings[a].atoms.indexOf(e.atoms[d])){b=!1;break}if(b){d=
!0;break}}d||this.rings.push(e)}}}this.fuse()}})(ChemDoodle.informatics,ChemDoodle.structures);
(function(f,q){f.SSSRFinder=function(n){this.rings=[];if(0<n.atoms.length){let r=(new f.FrerejacqueNumberCounter(n)).value,e=(new f.EulerFacetRingFinder(n)).rings;e.sort(function(e,b){return e.atoms.length-b.atoms.length});for(let e=0,b=n.bonds.length;e<b;e++)n.bonds[e].visited=!1;for(let f=0,b=e.length;f<b;f++){n=!1;for(let b=0,h=e[f].bonds.length;b<h;b++)if(!e[f].bonds[b].visited){n=!0;break}if(n){for(let b=0,h=e[f].bonds.length;b<h;b++)e[f].bonds[b].visited=!0;this.rings.push(e[f])}if(this.rings.length===
r)break}}}})(ChemDoodle.informatics);(function(f,q){f._Interpreter=function(){};f._Interpreter.prototype.fit=function(f,r,e){let k=f.length,b=[];for(let d=0;d<r-k;d++)b.push(" ");return e?f+b.join(""):b.join("")+f}})(ChemDoodle.io);
(function(f,q,n,r,e,k,b,d){let h=/\s+/g,a=/\(|\)|\s+/g,g=/'|\s+/g,l=/,|'|\s+/g,v=/^\s+/,m=/[0-9]/g,x=/[0-9]|\+|\-/g,u=function(a){return 0!==a.length},w={P:[],A:[[0,.5,.5]],B:[[.5,0,.5]],C:[[.5,.5,0]],I:[[.5,.5,.5]],R:[[2/3,1/3,1/3],[1/3,2/3,2/3]],S:[[1/3,1/3,2/3],[2/3,2/3,1/3]],T:[[1/3,2/3,1/3],[2/3,1/3,2/3]],F:[[0,.5,.5],[.5,0,.5],[.5,.5,0]]},z=function(a){let b=0,c=0,d=0,e=0;var f=a.indexOf("x"),g=a.indexOf("y");let h=a.indexOf("z");-1!==f&&(c++,0<f&&"+"!==a.charAt(f-1)&&(c*=-1));-1!==g&&(d++,
0<g&&"+"!==a.charAt(g-1)&&(d*=-1));-1!==h&&(e++,0<h&&"+"!==a.charAt(h-1)&&(e*=-1));if(2<a.length){f="+";for(let c=0,d=a.length;c<d;c++)g=a.charAt(c),"-"!==g&&"/"!==g||c!==a.length-1&&!a.charAt(c+1).match(m)||(f=g),g.match(m)&&("+"===f?b+=parseInt(g):"-"===f?b-=parseInt(g):"/"===f&&(b/=parseInt(g)))}return[b,c,d,e]};q.CIFInterpreter=function(){};(q.CIFInterpreter.prototype=new q._Interpreter).read=function(b,m,q,y){m=m?m:1;q=q?q:1;y=y?y:1;let c=new n.Molecule;if(!b)return c;let p=b.split("\n"),A=0,
C=0,G=0,J=0,H=0,X=0,na="P",Q,ca,da,M,oa=!0;for(;0<p.length;)if(oa?M=p.shift():oa=!0,0<M.length)if(M.startsWith("_cell_length_a"))A=parseFloat(M.split(a)[1]);else if(M.startsWith("_cell_length_b"))C=parseFloat(M.split(a)[1]);else if(M.startsWith("_cell_length_c"))G=parseFloat(M.split(a)[1]);else if(M.startsWith("_cell_angle_alpha"))J=e.PI*parseFloat(M.split(a)[1])/180;else if(M.startsWith("_cell_angle_beta"))H=e.PI*parseFloat(M.split(a)[1])/180;else if(M.startsWith("_cell_angle_gamma"))X=e.PI*parseFloat(M.split(a)[1])/
180;else if(M.startsWith("_symmetry_space_group_name_H-M"))na=M.split(g)[1];else if(M.startsWith("loop_")){let a={fields:[],lines:[]},b=!1;for(;(M=p.shift())!==d&&!(M=M.replace(v,"")).startsWith("loop_")&&0<M.length;)if(M.startsWith("_")){if(b)break;a.fields=a.fields.concat(M.split(h).filter(u))}else b=!0,a.lines.push(M);0!==p.length&&(M.startsWith("loop_")||M.startsWith("_"))&&(oa=!1);-1!==a.fields.indexOf("_symmetry_equiv_pos_as_xyz")||-1!==a.fields.indexOf("_space_group_symop_operation_xyz")?Q=
a:-1!==a.fields.indexOf("_atom_site_label")?ca=a:-1!==a.fields.indexOf("_geom_bond_atom_site_label_1")&&(da=a)}{var qa=A,ra=C,sa=G,V=H,Y=X;let a=(e.cos(J)-e.cos(Y)*e.cos(V))/e.sin(Y);var T=[qa,0,0,0,ra*e.cos(Y),ra*e.sin(Y),0,0,sa*e.cos(V),sa*a,sa*e.sqrt(1-e.pow(e.cos(V),2)-a*a),0,0,0,0,1]}if(ca){let a=-1,b=-1,d=-1,e=-1,f=-1;for(let c=0,g=ca.fields.length;c<g;c++){let g=ca.fields[c];"_atom_site_type_symbol"===g?a=c:"_atom_site_label"===g?b=c:"_atom_site_fract_x"===g?d=c:"_atom_site_fract_y"===g?e=
c:"_atom_site_fract_z"===g&&(f=c)}for(let g=0,m=ca.lines.length;g<m;g++){M=ca.lines[g];let m=M.split(h).filter(u),l=new n.Atom(m[-1===a?b:a].split(x)[0],parseFloat(m[d]),parseFloat(m[e]),parseFloat(m[f]));c.atoms.push(l);-1!==b&&(l.cifId=m[b],l.cifPart=0)}}if(Q&&!da){let a=0;for(let b=0,c=Q.fields.length;b<c;b++){let c=Q.fields[b];if("_symmetry_equiv_pos_as_xyz"===c||"_space_group_symop_operation_xyz"===c)a=b}let b=w[na],e=[];for(let f=0,g=Q.lines.length;f<g;f++){let g=Q.lines[f].split(l).filter(u),
h=z(g[a]),m=z(g[a+1]),k=z(g[a+2]);for(let a=0,g=c.atoms.length;a<g;a++){let g=c.atoms[a],l=g.x*h[1]+g.y*h[2]+g.z*h[3]+h[0],v=g.x*m[1]+g.y*m[2]+g.z*m[3]+m[0],p=g.x*k[1]+g.y*k[2]+g.z*k[3]+k[0],u=new n.Atom(g.label,l,v,p);e.push(u);g.cifId!==d&&(u.cifId=g.cifId,u.cifPart=f+1);if(b)for(let a=0,c=b.length;a<c;a++){let c=b[a],h=new n.Atom(g.label,l+c[0],v+c[1],p+c[2]);e.push(h);g.cifId!==d&&(h.cifId=g.cifId,h.cifPart=f+1)}}}for(let a=0,b=e.length;a<b;a++){let b=e[a];for(;1<=b.x;)b.x--;for(;0>b.x;)b.x++;
for(;1<=b.y;)b.y--;for(;0>b.y;)b.y++;for(;1<=b.z;)b.z--;for(;0>b.z;)b.z++}let f=[];for(let a=0,b=e.length;a<b;a++){let b=!1,d=e[a];for(let a=0,e=c.atoms.length;a<e;a++)if(1E-4>c.atoms[a].distance3D(d)){b=!0;break}if(!b){for(let a=0,c=f.length;a<c;a++)if(1E-4>f[a].distance3D(d)){b=!0;break}b||f.push(d)}}c.atoms=c.atoms.concat(f)}let R=[];for(let a=0;a<m;a++)for(let b=0;b<q;b++)for(let e=0;e<y;e++)if(0!==a||0!==b||0!==e)for(let f=0,g=c.atoms.length;f<g;f++){let g=c.atoms[f],h=new n.Atom(g.label,g.x+
a,g.y+b,g.z+e);R.push(h);g.cifId!==d&&(h.cifId=g.cifId,h.cifPart=g.cifPart+(Q?Q.lines.length:0)+a+10*b+100*e)}c.atoms=c.atoms.concat(R);for(let a=0,b=c.atoms.length;a<b;a++){let b=c.atoms[a],d=k.multiplyVec3(T,[b.x,b.y,b.z]);b.x=d[0];b.y=d[1];b.z=d[2]}if(da){let a=-1,b=-1;for(let c=0,d=da.fields.length;c<d;c++){let d=da.fields[c];"_geom_bond_atom_site_label_1"===d?a=c:"_geom_bond_atom_site_label_2"===d&&(b=c)}for(let d=0,e=da.lines.length;d<e;d++){let e=da.lines[d].split(h).filter(u),g=e[a],f=e[b];
for(let a=0,b=c.atoms.length;a<b;a++)for(let d=a+1;d<b;d++){let b=c.atoms[a],e=c.atoms[d];if(b.cifPart!==e.cifPart)break;(b.cifId===g&&e.cifId===f||b.cifId===f&&e.cifId===g)&&c.bonds.push(new n.Bond(b,e))}}}else(new f.informatics.BondDeducer).deduceCovalentBonds(c,1);let N=[-m/2,-q/2,-y/2],S={o:k.multiplyVec3(T,N,[]),x:k.multiplyVec3(T,[N[0]+1,N[1],N[2]]),y:k.multiplyVec3(T,[N[0],N[1]+1,N[2]]),z:k.multiplyVec3(T,[N[0],N[1],N[2]+1]),xy:k.multiplyVec3(T,[N[0]+1,N[1]+1,N[2]]),xz:k.multiplyVec3(T,[N[0]+
1,N[1],N[2]+1]),yz:k.multiplyVec3(T,[N[0],N[1]+1,N[2]+1]),xyz:k.multiplyVec3(T,[N[0]+1,N[1]+1,N[2]+1])};return{molecule:c,unitCell:new r.UnitCell(S)}};let y=new q.CIFInterpreter;f.readCIF=function(a,b,d,e){return y.read(a,b,d,e)}})(ChemDoodle,ChemDoodle.io,ChemDoodle.structures,ChemDoodle.structures.d3,Math,ChemDoodle.lib.mat4,ChemDoodle.lib.vec3);
(function(f,q,n,r,e){q.CMLInterpreter=function(){};let k=q.CMLInterpreter.prototype=new q._Interpreter;k.read=function(b){let d=[];b=r.parseXML(b);b=r(b).find("cml");for(let h=0,l=b.length;h<l;h++){let l=r(b[h]).find("molecule");for(let b=0,h=l.length;b<h;b++){let c=d[b]=new n.Molecule,h=[];var a=r(l[b]).find("atom");for(let c=0,l=a.length;c<l;c++){var g=r(a[c]),f=g.attr("elementType");let l;if(g.attr("x2")==e){var k=g.attr("x3");var m=g.attr("y3");l=g.attr("z3")}else k=g.attr("x2"),m=g.attr("y2"),
l=0;f=d[b].atoms[c]=new n.Atom(f,k,m,l);h[c]=g.attr("id");g.attr("formalCharge")!=e&&(f.charge=g.attr("formalCharge"))}a=r(l[b]).find("bond");for(let e=0,l=a.length;e<l;e++){g=r(a[e]);k=g.attr("atomRefs2").split(" ");f=c.atoms[r.inArray(k[0],h)];k=c.atoms[r.inArray(k[1],h)];switch(g.attr("order")){case "2":case "D":m=2;break;case "3":case "T":m=3;break;case "A":m=1.5;break;default:m=1}f=d[b].bonds[e]=new n.Bond(f,k,m);switch(g.find("bondStereo").text()){case "W":f.stereo=n.Bond.STEREO_PROTRUDING;
break;case "H":f.stereo=n.Bond.STEREO_RECESSED}}}}return d};k.write=function(b){let d=[];d.push('\x3c?xml version\x3d"1.0" encoding\x3d"UTF-8"?\x3e\n');d.push('\x3ccml convention\x3d"conventions:molecular" xmlns\x3d"http://www.xml-cml.org/schema" xmlns:conventions\x3d"http://www.xml-cml.org/convention/" xmlns:dc\x3d"http://purl.org/dc/elements/1.1/"\x3e\n');for(let e=0,f=b.length;e<f;e++){d.push('\x3cmolecule id\x3d"m');d.push(e);d.push('"\x3e');d.push("\x3catomArray\x3e");for(let f=0,g=b[e].atoms.length;f<
g;f++){var a=b[e].atoms[f];d.push('\x3catom elementType\x3d"');d.push(a.label);d.push('" id\x3d"a');d.push(f);d.push('" ');d.push('x3\x3d"');d.push(a.x);d.push('" y3\x3d"');d.push(a.y);d.push('" z3\x3d"');d.push(a.z);d.push('" ');0!=a.charge&&(d.push('formalCharge\x3d"'),d.push(a.charge),d.push('" '));d.push("/\x3e")}d.push("\x3c/atomArray\x3e");d.push("\x3cbondArray\x3e");for(let f=0,g=b[e].bonds.length;f<g;f++){a=b[e].bonds[f];d.push('\x3cbond atomRefs2\x3d"a');d.push(b[e].atoms.indexOf(a.a1));
d.push(" a");d.push(b[e].atoms.indexOf(a.a2));d.push('" order\x3d"');switch(a.bondOrder){case 1.5:d.push("A");break;case 1:case 2:case 3:d.push(a.bondOrder);break;default:d.push("S")}d.push('"/\x3e')}d.push("\x3c/bondArray\x3e");d.push("\x3c/molecule\x3e")}d.push("\x3c/cml\x3e");return d.join("")};let b=new q.CMLInterpreter;f.readCML=function(d){return b.read(d)};f.writeCML=function(d){return b.write(d)}})(ChemDoodle,ChemDoodle.io,ChemDoodle.structures,ChemDoodle.lib.jQuery);
(function(f,q,n,r,e){n.MOLInterpreter=function(){};e=n.MOLInterpreter.prototype=new n._Interpreter;e.read=function(b,d){d||(d=f.DEFAULT_STYLES.bondLength_2D);let e=new r.Molecule;if(!b)return e;b=b.split("\n");var a=b[3];let g=parseInt(a.substring(0,3));a=parseInt(a.substring(3,6));for(var l=0;l<g;l++){var k=b[4+l];e.atoms[l]=new r.Atom(k.substring(31,34),parseFloat(k.substring(0,10))*d,(1===d?1:-1)*parseFloat(k.substring(10,20))*d,parseFloat(k.substring(20,30))*d);var m=parseInt(k.substring(34,36));
0!==m&&q[e.atoms[l].label]&&(e.atoms[l].mass=q[e.atoms[l].label].mass+m);switch(parseInt(k.substring(36,39))){case 1:e.atoms[l].charge=3;break;case 2:e.atoms[l].charge=2;break;case 3:e.atoms[l].charge=1;break;case 5:e.atoms[l].charge=-1;break;case 6:e.atoms[l].charge=-2;break;case 7:e.atoms[l].charge=-3}}for(d=0;d<a;d++){k=b[4+g+d];m=parseInt(k.substring(6,9));l=parseInt(k.substring(9,12));if(3<m)switch(m){case 4:m=1.5;break;default:m=1}k=new r.Bond(e.atoms[parseInt(k.substring(0,3))-1],e.atoms[parseInt(k.substring(3,
6))-1],m);switch(l){case 3:k.stereo=r.Bond.STEREO_AMBIGUOUS;break;case 1:k.stereo=r.Bond.STEREO_PROTRUDING;break;case 6:k.stereo=r.Bond.STEREO_RECESSED}e.bonds[d]=k}return e};e.write=function(b){let d=[];d.push("Molecule from ChemDoodle Web Components\n\nhttp://www.ichemlabs.com\n");d.push(this.fit(b.atoms.length.toString(),3));d.push(this.fit(b.bonds.length.toString(),3));d.push("  0  0  0  0            999 V2000\n");var e=b.getCenter();for(let h=0,k=b.atoms.length;h<k;h++){var a=b.atoms[h];let m=
" 0";if(-1!==a.mass&&q[a.label]){var g=a.mass-q[a.label].mass;5>g&&-4<g&&(m=(-1<g?" ":"")+g)}g="  0";if(0!==a.charge)switch(a.charge){case 3:g="  1";break;case 2:g="  2";break;case 1:g="  3";break;case -1:g="  5";break;case -2:g="  6";break;case -3:g="  7"}d.push(this.fit(((a.x-e.x)/f.DEFAULT_STYLES.bondLength_2D).toFixed(4),10));d.push(this.fit((-(a.y-e.y)/f.DEFAULT_STYLES.bondLength_2D).toFixed(4),10));d.push(this.fit((a.z/f.DEFAULT_STYLES.bondLength_2D).toFixed(4),10));d.push(" ");d.push(this.fit(a.label,
3,!0));d.push(m);d.push(g);d.push("  0  0  0  0\n")}for(let f=0,g=b.bonds.length;f<g;f++){a=b.bonds[f];e=0;a.stereo===r.Bond.STEREO_AMBIGUOUS?e=3:a.stereo===r.Bond.STEREO_PROTRUDING?e=1:a.stereo===r.Bond.STEREO_RECESSED&&(e=6);d.push(this.fit((b.atoms.indexOf(a.a1)+1).toString(),3));d.push(this.fit((b.atoms.indexOf(a.a2)+1).toString(),3));a=a.bondOrder;if(1.5==a)a=4;else if(3<a||0!=a%1)a=1;d.push(this.fit(a.toString(),3));d.push("  ");d.push(e);d.push("  0  0  0\n")}d.push("M  END");return d.join("")};
let k=new n.MOLInterpreter;f.readMOL=function(b,d){return k.read(b,d)};f.writeMOL=function(b){return k.write(b)}})(ChemDoodle,ChemDoodle.ELEMENT,ChemDoodle.io,ChemDoodle.structures);
(function(f,q,n,r,e,k,b){function d(a,b,d,e,f){for(let g=0,h=b.length;g<h;g++){let h=b[g];if(h.id===d&&e>=h.start&&e<=h.end){f?a.helix=!0:a.sheet=!0;e===h.end&&(a.arrow=!0);break}}}q.PDBInterpreter=function(){};b=q.PDBInterpreter.prototype=new q._Interpreter;b.calculateRibbonDistances=!1;b.deduceResidueBonds=!1;b.read=function(a,b){let g=new n.Molecule;g.chains=[];if(!a)return g;var h=a.split("\n");b||(b=1);var m=[];let q=[];let u=[];a=[];let w=[];for(let f=0,l=h.length;f<l;f++){var z=h[f];if(z.startsWith("HELIX"))m.push({id:z.substring(19,
20),start:parseInt(z.substring(21,25)),end:parseInt(z.substring(33,37))});else if(z.startsWith("SHEET"))q.push({id:z.substring(21,22),start:parseInt(z.substring(22,26)),end:parseInt(z.substring(33,37))});else if(z.startsWith("ATOM")){var y=z.substring(16,17);if(" "===y||"A"===y){y=e(z.substring(76,78));if(0===y.length){var c=e(z.substring(12,14));"HD"===c?y="H":0<c.length&&(y=1<c.length?c.charAt(0)+c.substring(1).toLowerCase():c)}y=new n.Atom(y,parseFloat(z.substring(30,38))*b,parseFloat(z.substring(38,
46))*b,parseFloat(z.substring(46,54))*b);y.hetatm=!1;a.push(y);c=parseInt(z.substring(22,26));if(0===u.length)for(var p=0;3>p;p++){var A=new n.Residue(-1);A.cp1=y;A.cp2=y;u.push(A)}u[u.length-1].resSeq!==c&&(p=new n.Residue(c),p.name=e(z.substring(17,20)),3===p.name.length?p.name=p.name.substring(0,1)+p.name.substring(1).toLowerCase():2===p.name.length&&"D"===p.name.charAt(0)&&(p.name=p.name.substring(1)),u.push(p),A=z.substring(21,22),d(p,m,A,c,!0),d(p,q,A,c,!1));z=e(z.substring(12,16));c=u[u.length-
1];if("CA"===z||"P"===z||"O5'"===z)c.cp1||(c.cp1=y);else if("N3"===z&&("C"===c.name||"U"===c.name||"T"===c.name)||"N1"===z&&("A"===c.name||"G"===c.name))c.cp3=y;else if("C2"===z)c.cp4=y;else if("C4"===z&&("C"===c.name||"U"===c.name||"T"===c.name)||"C6"===z&&("A"===c.name||"G"===c.name))c.cp5=y;else if("O"===z||"C6"===z&&("C"===c.name||"U"===c.name||"T"===c.name)||"N9"===z){if(!u[u.length-1].cp2){if("C6"===z||"N9"===z)var C=y;c.cp2=y}}else"C"===z&&(C=y)}}else if(z.startsWith("HETATM"))y=e(z.substring(76,
78)),0===y.length&&(y=e(z.substring(12,16))),1<y.length&&(y=y.substring(0,1)+y.substring(1).toLowerCase()),y=new n.Atom(y,parseFloat(z.substring(30,38))*b,parseFloat(z.substring(38,46))*b,parseFloat(z.substring(46,54))*b),y.hetatm=!0,"HOH"===e(z.substring(17,20))&&(y.isWater=!0),g.atoms.push(y),w[parseInt(e(z.substring(6,11)))]=y;else if(z.startsWith("CONECT")){if(y=parseInt(e(z.substring(6,11))),w[y])for(y=w[y],c=0;4>c;c++)if(p=e(z.substring(11+5*c,16+5*c)),0!==p.length&&(p=parseInt(p),w[p])){p=
w[p];A=!1;for(let a=0,b=g.bonds.length;a<b;a++){let b=g.bonds[a];if(b.a1===y&&b.a2===p||b.a1===p&&b.a2===y){A=!0;break}}A||g.bonds.push(new n.Bond(y,p))}}else if(z.startsWith("TER"))this.endChain(g,u,C,a),u=[];else if(z.startsWith("ENDMDL"))break}this.endChain(g,u,C,a);0===g.bonds.size&&(new f.informatics.BondDeducer).deduceCovalentBonds(g,b);if(this.deduceResidueBonds)for(let c=0,d=a.length;c<d;c++)for(b=k.min(d,c+20),C=c+1;C<b;C++)h=a[c],m=a[C],h.distance3D(m)<1.1*(r[h.label].covalentRadius+r[m.label].covalentRadius)&&
g.bonds.push(new n.Bond(h,m,1));g.atoms=g.atoms.concat(a);this.calculateRibbonDistances&&this.calculateDistances(g,a);return g};b.endChain=function(a,b,d,e){if(0<b.length){var f=b[b.length-1];f.cp1||(f.cp1=e[e.length-2]);f.cp2||(f.cp2=e[e.length-1]);for(e=0;4>e;e++)f=new n.Residue(-1),f.cp1=d,f.cp2=b[b.length-1].cp2,b.push(f);a.chains.push(b)}};b.calculateDistances=function(a,b){let d=[];for(let b=0,e=a.atoms.length;b<e;b++){let e=a.atoms[b];e.hetatm&&(e.isWater||d.push(e))}for(let e=0,f=b.length;e<
f;e++)if(a=b[e],a.closestDistance=Number.POSITIVE_INFINITY,0===d.length)a.closestDistance=0;else for(let b=0,e=d.length;b<e;b++)a.closestDistance=Math.min(a.closestDistance,a.distance3D(d[b]))};let h=new q.PDBInterpreter;f.readPDB=function(a,b){return h.read(a,b)}})(ChemDoodle,ChemDoodle.io,ChemDoodle.structures,ChemDoodle.ELEMENT,ChemDoodle.lib.jQuery.trim,Math);
(function(f,q,n,r,e){let k={"@":0,A:1,B:2,C:3,D:4,E:5,F:6,G:7,H:8,I:9,a:-1,b:-2,c:-3,d:-4,e:-5,f:-6,g:-7,h:-8,i:-9},b={"%":0,J:1,K:2,L:3,M:4,N:5,O:6,P:7,Q:8,R:9,j:-1,k:-2,l:-3,m:-4,n:-5,o:-6,p:-7,q:-8,r:-9},d={S:1,T:2,U:3,V:4,W:5,X:6,Y:7,Z:8,s:9};q.JCAMPInterpreter=function(){};r=q.JCAMPInterpreter.prototype=new q._Interpreter;r.convertHZ2PPM=!1;r.read=function(a){this.isBreak=function(a){return k[a]!==e||b[a]!==e||d[a]!==e||" "===a||"-"===a||"+"===a};this.getValue=function(a,c){let d=a.charAt(0);
a=a.substring(1);return k[d]!==e?parseFloat(k[d]+a):b[d]!==e?parseFloat(b[d]+a)+c:parseFloat(a)};let f=new n.Spectrum;if(a===e||0===a.length)return f;a=a.split("\n");let h=[],v,m,q,u,r=1,z=1,y=1,c=-1;var p=-1;let A=!0,C=!1;for(let g=0,l=a.length;g<l;g++){var B=a[g].trim(),D=B.indexOf("$$");-1!==D&&(B=B.substring(0,D));if(0!==h.length&&a[g].startsWith("##"))if(D=h.join(""),A&&100>D.length&&f.metadata.push(D),h=[B],D.startsWith("##TITLE\x3d"))f.title=D.substring(8).trim();else if(D.startsWith("##XUNITS\x3d"))f.xUnit=
D.substring(9).trim(),this.convertHZ2PPM&&"HZ"===f.xUnit.toUpperCase()&&(f.xUnit="PPM",C=!0);else if(D.startsWith("##YUNITS\x3d"))f.yUnit=D.substring(9).trim();else{if(!D.startsWith("##XYPAIRS\x3d"))if(D.startsWith("##FIRSTX\x3d"))m=parseFloat(D.substring(9).trim());else if(D.startsWith("##LASTX\x3d"))v=parseFloat(D.substring(8).trim());else if(D.startsWith("##FIRSTY\x3d"))q=parseFloat(D.substring(9).trim());else if(D.startsWith("##NPOINTS\x3d"))u=parseFloat(D.substring(10).trim());else if(D.startsWith("##XFACTOR\x3d"))r=
parseFloat(D.substring(10).trim());else if(D.startsWith("##YFACTOR\x3d"))z=parseFloat(D.substring(10).trim());else if(D.startsWith("##DELTAX\x3d"))parseFloat(D.substring(9).trim());else if(D.startsWith("##.OBSERVE FREQUENCY\x3d"))this.convertHZ2PPM&&(y=parseFloat(D.substring(21).trim()));else if(D.startsWith("##.SHIFT REFERENCE\x3d"))this.convertHZ2PPM&&(p=D.substring(19).split(","),c=parseInt(p[2].trim()),p=parseFloat(p[3].trim()));else if(D.startsWith("##XYDATA\x3d")){C||(y=1);B=A=!1;D=D.split("\n");
var E=(v-m)/(u-1),K=m-E,G=q,J=0;let a;for(let c=1,g=D.length;c<g;c++){var H=[];K=D[c].trim();G=[];for(let a=0,b=K.length;a<b;a++)this.isBreak(K.charAt(a))?(0<G.length&&(1!==G.length||" "!==G[0])&&H.push(G.join("")),G=[K.charAt(a)]):G.push(K.charAt(a));H.push(G.join(""));K=parseFloat(H[0])*r-E;for(let c=1,g=H.length;c<g;c++)if(G=H[c],d[G.charAt(0)]!==e){let b=parseInt(d[G.charAt(0)]+G.substring(1))-1;for(let c=0;c<b;c++)K+=E,J=this.getValue(a,J),G=J*z,f.data[f.data.length-1]=new n.Point(K/y,G)}else k[G.charAt(0)]!==
e&&B?G=this.getValue(G,J)*z:(B=b[G.charAt(0)]!==e,a=G,K+=E,J=this.getValue(G,J),G=J*z,f.data.push(new n.Point(K/y,G)))}if(-1!==c){B=p-f.data[c-1].x;for(let a=0,b=f.data.length;a<b;a++)f.data[a].x+=B}}else if(D.startsWith("##PEAK TABLE\x3d")){A=!1;f.continuous=!1;B=D.split("\n");D=/[\s,]+/;for(let a=1,b=B.length;a<b;a++){E=B[a].split(D);for(let a=0,b=E.length;a+1<b;a+=2)f.data.push(new n.Point(parseFloat(E[a].trim()),parseFloat(E[a+1].trim())))}}else if(D.startsWith("##ATOMLIST\x3d")){f.molecule=new n.Molecule;
B=D.split("\n");D=/[\s]+/;for(let a=1,b=B.length;a<b;a++)E=B[a].split(D),f.molecule.atoms.push(new n.Atom(E[1]))}else if(D.startsWith("##BONDLIST\x3d")){B=D.split("\n");D=/[\s]+/;for(let a=1,b=B.length;a<b;a++)E=B[a].split(D),J=1,"D"===E[2]?J=2:"T"===E[2]&&(J=3),f.molecule.bonds.push(new n.Bond(f.molecule.atoms[parseInt(E[0])-1],f.molecule.atoms[parseInt(E[1])-1],J))}else if(f.molecule&&D.startsWith("##XY_RASTER\x3d")){B=D.split("\n");D=/[\s]+/;for(let a=1,b=B.length;a<b;a++)E=B[a].split(D),J=f.molecule.atoms[parseInt(E[0])-
1],J.x=parseInt(E[1]),J.y=parseInt(E[2]),4==E.length&&(J.z=parseInt(E[3]));f.molecule.scaleToAverageBondLength(20)}else if(D.startsWith("##PEAK ASSIGNMENTS\x3d")){B=D.split("\n");D=/[\s,()<>]+/;f.assignments=[];for(let a=1,b=B.length;a<b;a++){H=B[a].split(D);E=parseFloat(H[1]);J=parseFloat(H[2]);H=f.molecule.atoms[parseInt(H[3])-1];K=!1;for(let a=0,b=f.assignments.length;a<b;a++)if(G=f.assignments[a],G.x===E){G.as.push(H);H.assigned=G;K=!0;break}K||(E={x:E,y:J,as:[H]},H.assigned=E,f.assignments.push(E))}}}else B=
B.trim(),0!==h.length&&0!==B.length&&h.push("\n"),h.push(B)}f.setup();return f};r.makeStructureSpectrumSet=function(a,b){this.convertHZ2PPM=!0;let d=this.read(b),g=new f.ViewerCanvas(a+"_molecule",200,200);g.styles.atoms_displayTerminalCarbonLabels_2D=!0;g.styles.atoms_displayImplicitHydrogens_2D=!0;g.mouseout=function(a){if(0!==this.molecules.length){for(let a=0,b=this.molecules[0].atoms.length;a<b;a++)this.molecules[0].atoms[a].isHover=!1;d.hovered=e;this.repaint();h.repaint()}};g.touchend=g.mouseout;
g.mousemove=function(a){if(0!==this.molecules.length){let b=e;for(let d=0,f=this.molecules[0].atoms.length;d<f;d++){let f=this.molecules[0].atoms[d];f.isHover=!1;f.assigned&&(b===e||a.p.distance(f)<a.p.distance(b))&&(b=f)}d.hovered=e;if(20>a.p.distance(b)){for(let a=0,d=b.assigned.as.length;a<d;a++)b.assigned.as[a].isHover=!0;h.spectrum.hovered=b.assigned}this.repaint();h.repaint()}};g.touchmove=g.mousemove;g.drawChildExtras=function(a,b){if(0!==this.molecules.length)for(let d=0,e=this.molecules[0].atoms.length;d<
e;d++)this.molecules[0].atoms[d].drawDecorations(a,b)};let h=new f.ObserverCanvas(a+"_spectrum",400,200);h.styles.plots_showYAxis=!1;h.styles.plots_flipXAxis=!0;h.mouseout=function(a){if(this.spectrum&&this.spectrum.assignments){for(let a=0,b=g.molecules[0].atoms.length;a<b;a++)g.molecules[0].atoms[a].isHover=!1;this.spectrum.hovered=e;g.repaint();this.repaint()}};h.touchend=h.mouseout;h.mousemove=function(a){if(this.spectrum&&this.spectrum.assignments){let b=e;for(let a=0,b=g.molecules[0].atoms.length;a<
b;a++)g.molecules[0].atoms[a].isHover=!1;this.spectrum.hovered=e;for(let d=0,f=this.spectrum.assignments.length;d<f;d++){let f=this.spectrum.assignments[d];if(b===e||Math.abs(this.spectrum.getTransformedX(f.x,this.styles,this.spectrum.memory.width,this.spectrum.memory.offsetLeft)-a.p.x)<Math.abs(this.spectrum.getTransformedX(b.x,this.styles,this.spectrum.memory.width,this.spectrum.memory.offsetLeft)-a.p.x))b=f}if(20>Math.abs(this.spectrum.getTransformedX(b.x,this.styles,this.spectrum.memory.width,
this.spectrum.memory.offsetLeft)-a.p.x)){for(let a=0,d=b.as.length;a<d;a++)b.as[a].isHover=!0;this.spectrum.hovered=b}g.repaint();this.repaint()}};h.touchmove=h.mousemove;h.drawChildExtras=function(a){if(this.spectrum&&this.spectrum.hovered){let b=this.spectrum.getTransformedX(this.spectrum.hovered.x,h.styles,this.spectrum.memory.width,this.spectrum.memory.offsetLeft);b>=this.spectrum.memory.offsetLeft&&b<this.spectrum.memory.width&&(a.save(),a.strokeStyle="#885110",a.lineWidth=3,a.beginPath(),a.moveTo(b,
this.spectrum.memory.height-this.spectrum.memory.offsetBottom),a.lineTo(b,this.spectrum.getTransformedY(this.spectrum.hovered.y,h.styles,this.spectrum.memory.height,this.spectrum.memory.offsetBottom,this.spectrum.memory.offsetTop)),a.stroke(),a.restore())}};d&&(h.loadSpectrum(d),d.molecule&&g.loadMolecule(d.molecule));return[g,h]};let h=new q.JCAMPInterpreter;h.convertHZ2PPM=!0;f.readJCAMP=function(a){return h.read(a)}})(ChemDoodle,ChemDoodle.io,ChemDoodle.structures,ChemDoodle.lib.jQuery);
(function(f,q,n,r,e,k,b){q.JSONInterpreter=function(){};let d=q.JSONInterpreter.prototype;d.contentTo=function(a,d){a||(a=[]);d||(d=[]);var e=0,f=0;for(let b=0,d=a.length;b<d;b++){let d=a[b];for(let a=0,b=d.atoms.length;a<b;a++)d.atoms[a].tmpid="a"+e++;for(let a=0,b=d.bonds.length;a<b;a++)d.bonds[a].tmpid="b"+f++}e=0;for(let a=0,b=d.length;a<b;a++)d[a].tmpid="s"+e++;e={};if(a&&0<a.length){e.m=[];for(let b=0,d=a.length;b<d;b++)e.m.push(this.molTo(a[b]))}if(d&&0<d.length){e.s=[];for(let a=0,b=d.length;a<
b;a++)e.s.push(this.shapeTo(d[a]))}for(let d=0,e=a.length;d<e;d++){f=a[d];for(let a=0,d=f.atoms.length;a<d;a++)f.atoms[a].tmpid=b;for(let a=0,d=f.bonds.length;a<d;a++)f.bonds[a].tmpid=b}for(let a=0,e=d.length;a<e;a++)d[a].tmpid=b;return e};d.contentFrom=function(a){let d={molecules:[],shapes:[]};if(a.m)for(let b=0,e=a.m.length;b<e;b++)d.molecules.push(this.molFrom(a.m[b]));if(a.s)for(let b=0,e=a.s.length;b<e;b++)d.shapes.push(this.shapeFrom(a.s[b],d.molecules));for(let e=0,f=d.molecules.length;e<
f;e++){a=d.molecules[e];for(let d=0,e=a.atoms.length;d<e;d++)a.atoms[d].tmpid=b;for(let d=0,e=a.bonds.length;d<e;d++)a.bonds[d].tmpid=b}for(let a=0,e=d.shapes.length;a<e;a++)d.shapes[a].tmpid=b;return d};d.queryTo=function(a){let b={},d=function(b,d,e,f){d&&(b[e]={v:f?a.outputRange(d.v):d.v,n:d.not})};a.type===n.Query.TYPE_ATOM?(d(b,a.elements,"as"),d(b,a.chirality,"@"),d(b,a.aromatic,"A"),d(b,a.charge,"C",!0),d(b,a.hydrogens,"H",!0),d(b,a.ringCount,"R",!0),d(b,a.saturation,"S"),d(b,a.connectivity,
"X",!0),d(b,a.connectivityNoH,"x",!0)):(d(b,a.orders,"bs"),d(b,a.stereo,"@"),d(b,a.aromatic,"A"),d(b,a.ringCount,"R",!0));return b};d.molTo=function(a){let b={a:[]};for(let f=0,g=a.atoms.length;f<g;f++){var d=a.atoms[f],e={x:d.x,y:d.y};d.tmpid&&(e.i=d.tmpid);"C"!==d.label&&(e.l=d.label);0!==d.z&&(e.z=d.z);0!==d.charge&&(e.c=d.charge);-1!==d.mass&&(e.m=d.mass);-1!==d.implicitH&&(e.h=d.implicitH);0!==d.numRadical&&(e.r=d.numRadical);0!==d.numLonePair&&(e.p=d.numLonePair);d.query&&(e.q=this.queryTo(d.query));
b.a.push(e)}if(0<a.bonds.length){b.b=[];for(let f=0,g=a.bonds.length;f<g;f++)d=a.bonds[f],e={b:a.atoms.indexOf(d.a1),e:a.atoms.indexOf(d.a2)},d.tmpid&&(e.i=d.tmpid),1!==d.bondOrder&&(e.o=d.bondOrder),d.stereo!==n.Bond.STEREO_NONE&&(e.s=d.stereo),d.query&&(e.q=this.queryTo(d.query)),b.b.push(e)}return b};d.queryFrom=function(a){let b=new n.Query(a.as?n.Query.TYPE_ATOM:n.Query.TYPE_BOND),d=function(a,b,d,e){b&&(a[d]={},a[d].v=e?a.parseRange(b.v):b.v,b.n&&(a[d].not=!0))};b.type===n.Query.TYPE_ATOM?(d(b,
a.as,"elements"),d(b,a["@"],"chirality"),d(b,a.A,"aromatic"),d(b,a.C,"charge",!0),d(b,a.H,"hydrogens",!0),d(b,a.R,"ringCount",!0),d(b,a.S,"saturation"),d(b,a.X,"connectivity",!0),d(b,a.x,"connectivityNoH",!0)):(d(b,a.bs,"orders"),d(b,a["@"],"stereo"),d(b,a.A,"aromatic"),d(b,a.R,"ringCount",!0));return b};d.molFrom=function(a){let d=new n.Molecule;for(let g=0,h=a.a.length;g<h;g++){var e=a.a[g],f=new n.Atom(e.l?e.l:"C",e.x,e.y);e.i&&(f.tmpid=e.i);e.z&&(f.z=e.z);e.c&&(f.charge=e.c);e.m&&(f.mass=e.m);
e.h&&(f.implicitH=e.h);e.r&&(f.numRadical=e.r);e.p&&(f.numLonePair=e.p);e.q&&(f.query=this.queryFrom(e.q));e.p_h!==b&&(f.hetatm=e.p_h);e.p_w!==b&&(f.isWater=e.p_w);e.p_d!==b&&(f.closestDistance=e.p_d);d.atoms.push(f)}if(a.b)for(let g=0,h=a.b.length;g<h;g++)e=a.b[g],f=new n.Bond(d.atoms[e.b],d.atoms[e.e],e.o===b?1:e.o),e.i&&(f.tmpid=e.i),e.s&&(f.stereo=e.s),e.q&&(f.query=this.queryFrom(e.q)),d.bonds.push(f);return d};d.shapeTo=function(a){let b={};a.tmpid&&(b.i=a.tmpid);if(a instanceof r.Line)b.t=
"Line",b.x1=a.p1.x,b.y1=a.p1.y,b.x2=a.p2.x,b.y2=a.p2.y,b.a=a.arrowType;else if(a instanceof r.Pusher)b.t="Pusher",b.o1=a.o1.tmpid,b.o2=a.o2.tmpid,1!==a.numElectron&&(b.e=a.numElectron);else if(a instanceof r.AtomMapping)b.t="AtomMapping",b.a1=a.o1.tmpid,b.a2=a.o2.tmpid;else if(a instanceof r.Bracket)b.t="Bracket",b.x1=a.p1.x,b.y1=a.p1.y,b.x2=a.p2.x,b.y2=a.p2.y,0!==a.charge&&(b.c=a.charge),0!==a.mult&&(b.m=a.mult),0!==a.repeat&&(b.r=a.repeat);else if(a instanceof r.DynamicBracket)b.t="DynamicBracket",
b.b1=a.b1.tmpid,b.b2=a.b2.tmpid,b.n1=a.n1,b.n2=a.n2,!0===a.flip&&(b.f=!0);else if(a instanceof r.VAP){b.t="VAP";b.x=a.asterisk.x;b.y=a.asterisk.y;1!==a.bondType&&(b.o=a.bondType);a.substituent&&(b.s=a.substituent.tmpid);b.a=[];for(let d=0,e=a.attachments.length;d<e;d++)b.a.push(a.attachments[d].tmpid)}else if(a instanceof e.Distance)b.t="Distance",b.a1=a.a1.tmpid,b.a2=a.a2.tmpid,a.node&&(b.n=a.node,b.o=a.offset);else if(a instanceof e.Angle)b.t="Angle",b.a1=a.a1.tmpid,b.a2=a.a2.tmpid,b.a3=a.a3.tmpid;
else if(a instanceof e.Torsion)b.t="Torsion",b.a1=a.a1.tmpid,b.a2=a.a2.tmpid,b.a3=a.a3.tmpid,b.a4=a.a4.tmpid;else if(a instanceof e._Surface){b.t="Surface";b.a=[];for(let d=0,e=a.atoms.length;d<e;d++)b.a.push(a.atoms[d].tmpid);a instanceof e.VDWSurface||(b.p=a.probeRadius);b.r=a.resolution;var d="vdw";a instanceof e.SASSurface?d="sas":e.SESSurface&&a instanceof e.SESSurface&&(d="ses");b.f=d}else if(a instanceof e.UnitCell)for(d in b.t="UnitCell",a.unitCell)b[d]=a.unitCell[d];return b};d.shapeFrom=
function(a,d){if("Line"===a.t){var f=new r.Line(new n.Point(a.x1,a.y1),new n.Point(a.x2,a.y2));f.arrowType=a.a}else if("Pusher"===a.t){var g,h;for(let b=0,e=d.length;b<e;b++){f=d[b];for(let b=0,d=f.atoms.length;b<d;b++){var k=f.atoms[b];k.tmpid===a.o1?g=k:k.tmpid===a.o2&&(h=k)}for(let b=0,d=f.bonds.length;b<d;b++)k=f.bonds[b],k.tmpid===a.o1?g=k:k.tmpid===a.o2&&(h=k)}f=new r.Pusher(g,h);a.e&&(f.numElectron=a.e)}else if("AtomMapping"===a.t){let b;for(let e=0,h=d.length;e<h;e++){f=d[e];for(let d=0,c=
f.atoms.length;d<c;d++)g=f.atoms[d],g.tmpid===a.a1?k=g:g.tmpid===a.a2&&(b=g)}f=new r.AtomMapping(k,b)}else if("Bracket"===a.t)f=new r.Bracket(new n.Point(a.x1,a.y1),new n.Point(a.x2,a.y2)),a.c!==b&&(f.charge=a.c),a.m!==b&&(f.mult=a.m),a.r!==b&&(f.repeat=a.r);else if("DynamicBracket"===a.t){let b,e;for(let h=0,m=d.length;h<m;h++){f=d[h];for(let c=0,d=f.bonds.length;c<d;c++)g=f.bonds[c],g.tmpid===a.b1?b=g:g.tmpid===a.b2&&(e=g)}f=new r.DynamicBracket(b,e);f.n1=a.n1;f.n2=a.n2;a.f&&(f.flip=!0)}else if("VAP"===
a.t){f=new r.VAP(a.x,a.y);a.o&&(f.bondType=a.o);for(let b=0,e=d.length;b<e;b++){g=d[b];for(let b=0,d=g.atoms.length;b<d;b++)if(h=g.atoms[b],h.tmpid===a.s)f.substituent=h;else for(let b=0,d=a.a.length;b<d;b++)h.tmpid===a.a[b]&&f.attachments.push(h)}}else if("Distance"===a.t){let b,h;for(let e=0,m=d.length;e<m;e++){f=d[e];for(let c=0,d=f.atoms.length;c<d;c++)g=f.atoms[c],g.tmpid===a.a1?b=g:g.tmpid===a.a2&&(h=g)}f=new e.Distance(b,h,a.n,a.o)}else if("Angle"===a.t){let b,h,m;for(let e=0,c=d.length;e<
c;e++){f=d[e];for(let c=0,d=f.atoms.length;c<d;c++)g=f.atoms[c],g.tmpid===a.a1?b=g:g.tmpid===a.a2?h=g:g.tmpid===a.a3&&(m=g)}f=new e.Angle(b,h,m)}else if("Torsion"===a.t){let b,h,m,k;for(let c=0,e=d.length;c<e;c++){f=d[c];for(let c=0,d=f.atoms.length;c<d;c++)g=f.atoms[c],g.tmpid===a.a1?b=g:g.tmpid===a.a2?h=g:g.tmpid===a.a3?m=g:g.tmpid===a.a4&&(k=g)}f=new e.Torsion(b,h,m,k)}else if("Surface"===a.t){g=[];for(let b=0,e=d.length;b<e;b++){h=d[b];for(let b=0,d=h.atoms.length;b<d;b++){k=h.atoms[b];for(let b=
0,d=a.a.length;b<d;b++)k.tmpid===a.a[b]&&g.push(k)}}d=a.p?a.p:1.4;h=a.r?a.r:30;"vdw"===a.f?f=new e.VDWSurface(g,h):"sas"===a.f?f=new e.SASSurface(g,d,h):"ses"===a.f&&(f=new e.SESSurface(g,d,h))}else if("UnitCell"===a.t){d={};for(let b in a)d[b]=a[b];f=new e.UnitCell(d)}return f};d.pdbFrom=function(a){let b=this.molFrom(a.mol);b.findRings=!1;b.fromJSON=!0;b.chains=this.chainsFrom(a.ribbons);return b};d.chainsFrom=function(a){let b=[];for(let d=0,e=a.cs.length;d<e;d++){let e=a.cs[d],f=[];for(let a=
0,b=e.length;a<b;a++){let b=e[a],d=new n.Residue;d.name=b.n;d.cp1=new n.Atom("",b.x1,b.y1,b.z1);d.cp2=new n.Atom("",b.x2,b.y2,b.z2);b.x3&&(d.cp3=new n.Atom("",b.x3,b.y3,b.z3),d.cp4=new n.Atom("",b.x4,b.y4,b.z4),d.cp5=new n.Atom("",b.x5,b.y5,b.z5));d.helix=b.h;d.sheet=b.s;d.arrow=0<a&&e[a-1].a;f.push(d)}b.push(f)}return b};let h=new q.JSONInterpreter;f.readJSON=function(a){let d;try{d=k.parse(a)}catch(l){return b}return d?d.m||d.s?h.contentFrom(d):d.a?{molecules:[h.molFrom(d)],shapes:[]}:{molecules:[],
shapes:[]}:b};f.writeJSON=function(a,b){return k.stringify(h.contentTo(a,b))}})(ChemDoodle,ChemDoodle.io,ChemDoodle.structures,ChemDoodle.structures.d2,ChemDoodle.structures.d3,JSON);
(function(f,q,n,r){q.RXNInterpreter=function(){};let e=q.RXNInterpreter.prototype=new q._Interpreter;e.read=function(b,d){d||(d=f.DEFAULT_STYLES.bondLength_2D);let e=[];if(b){var a=b.split("$MOL\n");b=a[0].split("\n")[4];var g=parseInt(b.substring(0,3)),k=parseInt(b.substring(3,6)),q=1;b=0;for(let h=0,l=g+k;h<l;h++){e[h]=f.readMOL(a[q],d);let g=e[h].getBounds();b-=g.maxX-g.minX+40;q++}for(let f=0,h=g;f<h;f++){d=e[f].getBounds();d=d.maxX-d.minX;a=e[f].getCenter();for(let g=0,h=e[f].atoms.length;g<
h;g++)q=e[f].atoms[g],q.x+=b+d/2-a.x,q.y-=a.y;b+=d+40}d=new n.d2.Line(new n.Point(b,0),new n.Point(b+40,0));b+=80;for(let d=g,f=g+k;d<f;d++){g=e[d].getBounds();g=g.maxX-g.minX;k=e[d].getCenter();for(a=0;a<e[d].atoms.length;a++)q=e[d].atoms[a],q.x+=b+g/2-k.x,q.y-=k.y;b+=g+40}}else e.push(new n.Molecule),d=new n.d2.Line(new n.Point(-20,0),new n.Point(20,0));d.arrowType=n.d2.Line.ARROW_SYNTHETIC;return{molecules:e,shapes:[d]}};e.write=function(b,d){let e=[[],[]],a=r;if(b&&d){for(let b=0,e=d.length;b<
e;b++)if(d[b]instanceof n.d2.Line){a=d[b].getPoints();break}if(!a)return"";for(let d=0,f=b.length;d<f;d++)b[d].getCenter().x<a[1].x?e[0].push(b[d]):e[1].push(b[d]);b=[];b.push("$RXN\nReaction from ChemDoodle Web Components\n\nhttp://www.ichemlabs.com\n");b.push(this.fit(e[0].length.toString(),3));b.push(this.fit(e[1].length.toString(),3));b.push("\n");for(d=0;2>d;d++)for(let a=0,h=e[d].length;a<h;a++)b.push("$MOL\n"),b.push(f.writeMOL(e[d][a])),b.push("\n");return b.join("")}};let k=new q.RXNInterpreter;
f.readRXN=function(b,d){return k.read(b,d)};f.writeRXN=function(b,d){return k.write(b,d)}})(ChemDoodle,ChemDoodle.io,ChemDoodle.structures);
(function(f,q,n,r,e,k,b){r.XYZInterpreter=function(){};q=r.XYZInterpreter.prototype=new r._Interpreter;q.deduceCovalentBonds=!0;q.read=function(b){let a=new e.Molecule;if(!b)return a;b=b.split("\n");let d=parseInt(k(b[0]));for(let f=0;f<d;f++){let d=b[f+2].split(/\s+/g);a.atoms[f]=new e.Atom(isNaN(d[0])?d[0]:n[parseInt(d[0])-1],parseFloat(d[1]),parseFloat(d[2]),parseFloat(d[3]))}this.deduceCovalentBonds&&(new f.informatics.BondDeducer).deduceCovalentBonds(a,1);return a};let d=new r.XYZInterpreter;
f.readXYZ=function(b){return d.read(b)}})(ChemDoodle,ChemDoodle.ELEMENT,ChemDoodle.SYMBOLS,ChemDoodle.io,ChemDoodle.structures,ChemDoodle.lib.jQuery.trim);
ChemDoodle.monitor=function(f,q,n,r){let e={};e.CANVAS_DRAGGING=r;e.CANVAS_OVER=r;e.ALT=!1;e.SHIFT=!1;e.META=!1;f.supports_touch()||q(n).ready(function(){q(n).mousemove(function(f){e.CANVAS_DRAGGING&&e.CANVAS_DRAGGING.drag&&(e.CANVAS_DRAGGING.prehandleEvent(f),e.CANVAS_DRAGGING.drag(f))});q(n).mouseup(function(f){e.CANVAS_DRAGGING&&e.CANVAS_DRAGGING!==e.CANVAS_OVER&&e.CANVAS_DRAGGING.mouseup&&(e.CANVAS_DRAGGING.prehandleEvent(f),e.CANVAS_DRAGGING.mouseup(f));e.CANVAS_DRAGGING=r});q(n).keydown(function(f){e.SHIFT=
f.shiftKey;e.ALT=f.altKey;e.META=f.metaKey||f.ctrlKey;let b=e.CANVAS_OVER;e.CANVAS_DRAGGING&&(b=e.CANVAS_DRAGGING);b&&b.keydown&&(b.prehandleEvent(f),b.keydown(f))});q(n).keypress(function(f){let b=e.CANVAS_OVER;e.CANVAS_DRAGGING&&(b=e.CANVAS_DRAGGING);b&&b.keypress&&(b.prehandleEvent(f),b.keypress(f))});q(n).keyup(function(f){e.SHIFT=f.shiftKey;e.ALT=f.altKey;e.META=f.metaKey||f.ctrlKey;let b=e.CANVAS_OVER;e.CANVAS_DRAGGING&&(b=e.CANVAS_DRAGGING);b&&b.keyup&&(b.prehandleEvent(f),b.keyup(f))})});
return e}(ChemDoodle.featureDetection,ChemDoodle.lib.jQuery,document);
(function(f,q,n,r,e,k,b,d,h,a,g){f._Canvas=function(){};let l=f._Canvas.prototype;l.molecules=g;l.shapes=g;l.emptyMessage=g;l.image=g;l.repaint=function(){if(!this.test){var a=d.getElementById(this.id);if(a.getContext){let b=a.getContext("2d");1!==this.pixelRatio&&a.width===this.width&&(a.width=this.width*this.pixelRatio,a.height=this.height*this.pixelRatio,b.scale(this.pixelRatio,this.pixelRatio));if(this.image)b.drawImage(this.image,0,0);else{let d=this.styles.backgroundColor?this.styles.backgroundColor:
"transparent";b.clearRect(0,0,this.width,this.height);this.bgCache!==d&&(a.style.backgroundColor=d,this.bgCache=a.style.backgroundColor);"transparent"!==d&&(b.fillStyle=d,b.fillRect(0,0,this.width,this.height))}if(this.innerRepaint)this.innerRepaint(b);else if(0!==this.molecules.length||0!==this.shapes.length){b.save();b.translate(this.width/2,this.height/2);b.rotate(this.styles.rotateAngle);b.scale(this.styles.scale,this.styles.scale);b.translate(-this.width/2,-this.height/2);for(let a=0,d=this.molecules.length;a<
d;a++)this.molecules[a].check(!0),this.molecules[a].draw(b,this.styles);this.checksOnAction&&this.checksOnAction(!0);for(let a=0,d=this.shapes.length;a<d;a++)this.shapes[a].draw(b,this.styles);b.restore()}else this.emptyMessage&&(b.fillStyle="#737683",b.textAlign="center",b.textBaseline="middle",b.font="18px Helvetica, Verdana, Arial, Sans-serif",b.fillText(this.emptyMessage,this.width/2,this.height/2));this.drawChildExtras&&this.drawChildExtras(b,this.styles)}}};l.resize=function(a,b){let d=k("#"+
this.id);d.attr({width:a,height:b});d.css("width",a);d.css("height",b);this.width=a;this.height=b;if(f._Canvas3D&&this instanceof f._Canvas3D)1!==this.pixelRatio&&(a*=this.pixelRatio,b*=this.pixelRatio,this.gl.canvas.width=a,this.gl.canvas.height=b),this.gl.viewport(0,0,a,b),this.afterLoadContent();else if(0<this.molecules.length){this.center();for(let a=0,b=this.molecules.length;a<b;a++)this.molecules[a].check()}this.repaint()};l.setBackgroundImage=function(a){this.image=new Image;let b=this;this.image.onload=
function(){b.repaint()};this.image.src=a};l.loadMolecule=function(a){this.clear();this.molecules.push(a);for(let b=0;2>b;b++)this.center(),f._Canvas3D&&this instanceof f._Canvas3D||a.check(),this.afterLoadContent&&this.afterLoadContent(),this.repaint()};l.loadContent=function(a,b){this.molecules=a?a:[];this.shapes=b?b:[];for(a=0;2>a;a++){this.center();if(!(f._Canvas3D&&this instanceof f._Canvas3D))for(let a=0,b=this.molecules.length;a<b;a++)this.molecules[a].check();this.afterLoadContent&&this.afterLoadContent();
this.repaint()}};l.addMolecule=function(a){this.molecules.push(a);f._Canvas3D&&this instanceof f._Canvas3D||a.check();this.repaint()};l.removeMolecule=function(a){this.molecules=k.grep(this.molecules,function(b){return b!==a});this.repaint()};l.getMolecule=function(){return 0<this.molecules.length?this.molecules[0]:g};l.getMolecules=function(){return this.molecules};l.addShape=function(a){this.shapes.push(a);this.repaint()};l.removeShape=function(a){this.shapes=k.grep(this.shapes,function(b){return b!==
a});this.repaint()};l.getShapes=function(){return this.shapes};l.clear=function(){this.molecules=[];this.shapes=[];this.styles.scale=1;this.repaint()};l.center=function(){var a=this.getContentBounds(),d=new e.Point((this.width-a.minX-a.maxX)/2,(this.height-a.minY-a.maxY)/2);for(let a=0,b=this.molecules.length;a<b;a++){var f=this.molecules[a];for(let a=0,b=f.atoms.length;a<b;a++)f.atoms[a].add(d)}for(let a=0,b=this.shapes.length;a<b;a++){f=this.shapes[a].getPoints();for(let a=0,b=f.length;a<b;a++)f[a].add(d)}this.styles.scale=
1;d=a.maxX-a.minX;a=a.maxY-a.minY;if(d>this.width-20||a>this.height-20)this.styles.scale=.85*b.min(this.width/d,this.height/a)};l.bondExists=function(a,b){for(let d=0,e=this.molecules.length;d<e;d++){let e=this.molecules[d];for(let d=0,f=e.bonds.length;d<f;d++){let c=e.bonds[d];if(c.contains(a)&&c.contains(b))return!0}}return!1};l.getBond=function(a,b){for(let d=0,e=this.molecules.length;d<e;d++){let e=this.molecules[d];for(let d=0,f=e.bonds.length;d<f;d++){let c=e.bonds[d];if(c.contains(a)&&c.contains(b))return c}}return g};
l.getMoleculeByAtom=function(a){for(let b=0,d=this.molecules.length;b<d;b++){let d=this.molecules[b];if(-1!==d.atoms.indexOf(a))return d}return h.undefined};l.getAllAtoms=function(){let a=[];for(let b=0,d=this.molecules.length;b<d;b++)a=a.concat(this.molecules[b].atoms);return a};l.getAllBonds=function(){let a=[];for(let b=0,d=this.molecules.length;b<d;b++)a=a.concat(this.molecules[b].bonds);return a};l.getAllPoints=function(){let a=[];for(let b=0,d=this.molecules.length;b<d;b++)a=a.concat(this.molecules[b].atoms);
for(let b=0,d=this.shapes.length;b<d;b++)a=a.concat(this.shapes[b].getPoints());return a};l.getContentBounds=function(){let a=new n.Bounds;for(let b=0,d=this.molecules.length;b<d;b++)a.expand(this.molecules[b].getBounds());for(let b=0,d=this.shapes.length;b<d;b++)a.expand(this.shapes[b].getBounds());return a};l.create=function(l,m,n){this.id=l;this.width=m;this.height=n;this.molecules=[];this.shapes=[];if(d.getElementById(l)){let a=k("#"+l);m?a.attr("width",m):this.width=parseInt(a.attr("width"));
n?a.attr("height",n):this.height=parseInt(a.attr("height"));a.attr("class","ChemDoodleWebComponent")}else if(f.featureDetection.supports_canvas_text()||-1==a.indexOf("MSIE"))d.writeln('\x3ccanvas class\x3d"ChemDoodleWebComponent" id\x3d"'+l+'" width\x3d"'+m+'" height\x3d"'+n+'" alt\x3d"ChemDoodle Web Component"\x3eThis browser does not support HTML5/Canvas.\x3c/canvas\x3e');else{d.writeln('\x3cdiv style\x3d"border: 1px solid black;" width\x3d"'+m+'" height\x3d"'+n+'"\x3ePlease install \x3ca href\x3d"http://code.google.com/chrome/chromeframe/"\x3eGoogle Chrome Frame\x3c/a\x3e, then restart Internet Explorer.\x3c/div\x3e');
return}l=k("#"+l);l.css("width",this.width);l.css("height",this.height);this.pixelRatio=h.devicePixelRatio?h.devicePixelRatio:1;this.styles=new e.Styles;let u=this;q.supports_touch()?(l.bind("touchstart",function(a){let b=(new Date).getTime();if(!q.supports_gesture()&&2===a.originalEvent.touches.length){var d=a.originalEvent.touches;let b=new e.Point(d[0].pageX,d[0].pageY);d=new e.Point(d[1].pageX,d[1].pageY);u.implementedGestureDist=b.distance(d);u.implementedGestureAngle=b.angle(d);u.gesturestart&&
(u.prehandleEvent(a),u.gesturestart(a))}u.lastTouch&&1===a.originalEvent.touches.length&&500>b-u.lastTouch?u.dbltap?(u.prehandleEvent(a),u.dbltap(a)):u.dblclick?(u.prehandleEvent(a),u.dblclick(a)):u.touchstart?(u.prehandleEvent(a),u.touchstart(a)):u.mousedown&&(u.prehandleEvent(a),u.mousedown(a)):u.touchstart?(u.prehandleEvent(a),u.touchstart(a),this.hold&&clearTimeout(this.hold),this.touchhold&&(this.hold=setTimeout(function(){u.touchhold(a)},1E3))):u.mousedown&&(u.prehandleEvent(a),u.mousedown(a));
u.lastTouch=b}),l.bind("touchmove",function(a){this.hold&&(clearTimeout(this.hold),this.hold=g);if(!q.supports_gesture()&&2===a.originalEvent.touches.length&&u.gesturechange){var d=a.originalEvent.touches,f=new e.Point(d[0].pageX,d[0].pageY),c=new e.Point(d[1].pageX,d[1].pageY);d=f.distance(c);f=f.angle(c);a.originalEvent.scale=d/u.implementedGestureDist;a.originalEvent.rotation=180*(u.implementedGestureAngle-f)/b.PI;u.prehandleEvent(a);u.gesturechange(a)}if(1<a.originalEvent.touches.length&&u.multitouchmove){f=
a.originalEvent.touches.length;u.prehandleEvent(a);d=new e.Point(-a.offset.left*f,-a.offset.top*f);for(c=0;c<f;c++)d.x+=a.originalEvent.changedTouches[c].pageX,d.y+=a.originalEvent.changedTouches[c].pageY;d.x/=f;d.y/=f;a.p=d;u.multitouchmove(a,f)}else u.touchmove?(u.prehandleEvent(a),u.touchmove(a)):u.drag&&(u.prehandleEvent(a),u.drag(a))}),l.bind("touchend",function(a){this.hold&&(clearTimeout(this.hold),this.hold=g);!q.supports_gesture()&&u.implementedGestureDist&&(u.implementedGestureDist=g,u.implementedGestureAngle=
g,u.gestureend&&(u.prehandleEvent(a),u.gestureend(a)));u.touchend?(u.prehandleEvent(a),u.touchend(a)):u.mouseup&&(u.prehandleEvent(a),u.mouseup(a));250>(new Date).getTime()-u.lastTouch&&(u.tap?(u.prehandleEvent(a),u.tap(a)):u.click&&(u.prehandleEvent(a),u.click(a)))}),l.bind("gesturestart",function(a){u.gesturestart&&(u.prehandleEvent(a),u.gesturestart(a))}),l.bind("gesturechange",function(a){u.gesturechange&&(u.prehandleEvent(a),u.gesturechange(a))}),l.bind("gestureend",function(a){u.gestureend&&
(u.prehandleEvent(a),u.gestureend(a))})):(l.click(function(a){switch(a.which){case 1:u.click&&(u.prehandleEvent(a),u.click(a));break;case 2:u.middleclick&&(u.prehandleEvent(a),u.middleclick(a));break;case 3:u.rightclick&&(u.prehandleEvent(a),u.rightclick(a))}}),l.dblclick(function(a){u.dblclick&&(u.prehandleEvent(a),u.dblclick(a))}),l.mousedown(function(a){switch(a.which){case 1:r.CANVAS_DRAGGING=u;u.mousedown&&(u.prehandleEvent(a),u.mousedown(a));break;case 2:u.middlemousedown&&(u.prehandleEvent(a),
u.middlemousedown(a));break;case 3:u.rightmousedown&&(u.prehandleEvent(a),u.rightmousedown(a))}}),l.mousemove(function(a){!r.CANVAS_DRAGGING&&u.mousemove&&(u.prehandleEvent(a),u.mousemove(a))}),l.mouseout(function(a){r.CANVAS_OVER=g;u.mouseout&&(u.prehandleEvent(a),u.mouseout(a))}),l.mouseover(function(a){r.CANVAS_OVER=u;u.mouseover&&(u.prehandleEvent(a),u.mouseover(a))}),l.mouseup(function(a){switch(a.which){case 1:u.mouseup&&(u.prehandleEvent(a),u.mouseup(a));break;case 2:u.middlemouseup&&(u.prehandleEvent(a),
u.middlemouseup(a));break;case 3:u.rightmouseup&&(u.prehandleEvent(a),u.rightmouseup(a))}}),l.mousewheel(function(a,b){u.mousewheel&&(u.prehandleEvent(a),u.mousewheel(a,b))}));this.subCreate&&this.subCreate()};l.prehandleEvent=function(a){a.originalEvent.changedTouches&&(a.pageX=a.originalEvent.changedTouches[0].pageX,a.pageY=a.originalEvent.changedTouches[0].pageY);this.doEventDefault||(a.preventDefault(),a.returnValue=!1);a.offset=k("#"+this.id).offset();a.p=new e.Point(a.pageX-a.offset.left,a.pageY-
a.offset.top)}})(ChemDoodle,ChemDoodle.featureDetection,ChemDoodle.math,ChemDoodle.monitor,ChemDoodle.structures,ChemDoodle.lib.jQuery,Math,document,window,navigator.userAgent);
(function(f,q,n){f._AnimatorCanvas=function(f,e,k){f&&this.create(f,e,k)};f=f._AnimatorCanvas.prototype=new f._Canvas;f.timeout=33;f.startAnimation=function(){this.stopAnimation();this.lastTime=(new Date).getTime();let f=this;this.nextFrame&&(this.handle=q.requestInterval(function(){let e=(new Date).getTime();f.nextFrame(e-f.lastTime);f.repaint();f.lastTime=e},this.timeout))};f.stopAnimation=function(){this.handle&&(q.clearRequestInterval(this.handle),this.handle=n)};f.isRunning=function(){return this.handle!==
n}})(ChemDoodle,ChemDoodle.animations);
(function(f,q,n){f.FileCanvas=function(f,e,k,b){f&&this.create(f,e,k);q.writeln('\x3cbr\x3e\x3cform name\x3d"FileForm" enctype\x3d"multipart/form-data" method\x3d"POST" action\x3d"'+b+'" target\x3d"HiddenFileFrame"\x3e\x3cinput type\x3d"file" name\x3d"f" /\x3e\x3cinput type\x3d"submit" name\x3d"submitbutton" value\x3d"Show File" /\x3e\x3c/form\x3e\x3ciframe id\x3d"HFF-'+f+'" name\x3d"HiddenFileFrame" height\x3d"0" width\x3d"0" style\x3d"display:none;" onLoad\x3d"GetMolFromFrame(\'HFF-'+f+"', "+f+
')"\x3e\x3c/iframe\x3e');this.emptyMessage="Click below to load file";this.repaint()};f.FileCanvas.prototype=new f._Canvas})(ChemDoodle,document);
(function(f,q){f.HyperlinkCanvas=function(f,q,e,k,b,d){f&&this.create(f,q,e);this.urlOrFunction=k;this.color=b?b:"blue";this.size=d?d:2};f=f.HyperlinkCanvas.prototype=new f._Canvas;f.openInNewWindow=!0;f.hoverImage=q;f.drawChildExtras=function(f){this.e&&(this.hoverImage?f.drawImage(this.hoverImage,0,0):(f.strokeStyle=this.color,f.lineWidth=2*this.size,f.strokeRect(0,0,this.width,this.height)))};f.setHoverImage=function(f){this.hoverImage=new Image;this.hoverImage.src=f};f.click=function(f){this.e=
q;this.repaint();this.urlOrFunction instanceof Function?this.urlOrFunction():this.openInNewWindow?window.open(this.urlOrFunction):location.href=this.urlOrFunction};f.mouseout=function(f){this.e=q;this.repaint()};f.mouseover=function(f){this.e=f;this.repaint()}})(ChemDoodle);
(function(f,q,n,r,e){f.MolGrabberCanvas=function(e,b,d){e&&this.create(e,b,d);b=[];b.push('\x3cbr\x3e\x3cinput type\x3d"text" id\x3d"');b.push(e);b.push('_query" size\x3d"32" value\x3d"" /\x3e');b.push(this.getInputFields());r.getElementById(e);n("#"+e).after(b.join(""));let f=this;n("#"+e+"_submit").click(function(){f.search()});n("#"+e+"_query").keypress(function(a){13===a.which&&f.search()});this.emptyMessage="Enter search term below";this.repaint()};f=f.MolGrabberCanvas.prototype=new f._Canvas;
f.setSearchTerm=function(e){n("#"+this.id+"_query").val(e);this.search()};f.getInputFields=function(){let e=[];e.push("\x3cbr\x3e\x3cnobr\x3e");e.push('\x3cselect id\x3d"');e.push(this.id);e.push('_select"\x3e');e.push('\x3coption value\x3d"chemexper"\x3eChemExper');e.push('\x3coption value\x3d"chemspider"\x3eChemSpider');e.push('\x3coption value\x3d"pubchem" selected\x3ePubChem');e.push("\x3c/select\x3e");e.push('\x3cbutton type\x3d"button" id\x3d"');e.push(this.id);e.push('_submit"\x3eShow Molecule\x3c/button\x3e');
e.push("\x3c/nobr\x3e");return e.join("")};f.search=function(){this.emptyMessage="Searching...";this.clear();let e=this;q.getMoleculeFromDatabase(n("#"+this.id+"_query").val(),{database:n("#"+this.id+"_select").val()},function(b){e.loadMolecule(b)})}})(ChemDoodle,ChemDoodle.iChemLabs,ChemDoodle.lib.jQuery,document);
(function(f,q,n,r){let e=[],k=[1,0,0],b=[0,1,0],d=[0,0,1];f.RotatorCanvas=function(b,a,d,e){b&&this.create(b,a,d);this.rotate3D=e};f=f.RotatorCanvas.prototype=new f._AnimatorCanvas;q=q.PI/15;f.xIncrement=q;f.yIncrement=q;f.zIncrement=q;f.nextFrame=function(f){if(0===this.molecules.length&&0===this.shapes.length)this.stopAnimation();else if(f/=1E3,this.rotate3D){n.identity(e);n.rotate(e,this.xIncrement*f,k);n.rotate(e,this.yIncrement*f,b);n.rotate(e,this.zIncrement*f,d);for(let b=0,d=this.molecules.length;b<
d;b++){f=this.molecules[b];for(let b=0,d=f.atoms.length;b<d;b++){var a=f.atoms[b],g=[a.x-this.width/2,a.y-this.height/2,a.z];n.multiplyVec3(e,g);a.x=g[0]+this.width/2;a.y=g[1]+this.height/2;a.z=g[2]}for(let a=0,b=f.rings.length;a<b;a++)f.rings[a].center=f.rings[a].getCenter();this.styles.atoms_display&&this.styles.atoms_circles_2D&&f.sortAtomsByZ();this.styles.bonds_display&&this.styles.bonds_clearOverlaps_2D&&f.sortBondsByZ()}for(let b=0,d=this.shapes.length;b<d;b++){f=this.shapes[b].getPoints();
for(let b=0,d=f.length;b<d;b++)a=f[b],g=[a.x-this.width/2,a.y-this.height/2,0],n.multiplyVec3(e,g),a.x=g[0]+this.width/2,a.y=g[1]+this.height/2}}else this.styles.rotateAngle+=this.zIncrement*f};f.dblclick=function(b){this.isRunning()?this.stopAnimation():this.startAnimation()}})(ChemDoodle,Math,ChemDoodle.lib.mat4);
(function(f,q,n,r){f.SlideshowCanvas=function(e,f,b){e&&this.create(e,f,b)};f=f.SlideshowCanvas.prototype=new f._AnimatorCanvas;f.frames=[];f.curIndex=0;f.timeout=5E3;f.alpha=0;f.innerHandle=r;f.phase=0;f.drawChildExtras=function(e){let f=n.getRGB(this.styles.backgroundColor,255);e.fillStyle="rgba("+f[0]+", "+f[1]+", "+f[2]+", "+this.alpha+")";e.fillRect(0,0,this.width,this.height)};f.nextFrame=function(e){if(0===this.frames.length)this.stopAnimation();else{this.phase=0;var f=this,b=1;this.innerHandle=
setInterval(function(){f.alpha=b/15;f.repaint();15===b&&f.breakInnerHandle();b++},33)}};f.breakInnerHandle=function(){this.innerHandle&&(clearInterval(this.innerHandle),this.innerHandle=r);if(0===this.phase){this.curIndex++;this.curIndex>this.frames.length-1&&(this.curIndex=0);this.alpha=1;let e=this.frames[this.curIndex];this.loadContent(e.mols,e.shapes);this.phase=1;let f=this,b=1;this.innerHandle=setInterval(function(){f.alpha=(15-b)/15;f.repaint();15===b&&f.breakInnerHandle();b++},33)}else 1===
this.phase&&(this.alpha=0,this.repaint())};f.addFrame=function(e,f){0===this.frames.length&&this.loadContent(e,f);this.frames.push({mols:e,shapes:f})}})(ChemDoodle,ChemDoodle.animations,ChemDoodle.math);
(function(f,q,n,r,e,k){f.TransformCanvas=function(b,d,e,a){b&&this.create(b,d,e);this.rotate3D=a};f=f.TransformCanvas.prototype=new f._Canvas;f.lastPoint=k;f.rotationMultMod=1.3;f.lastPinchScale=1;f.lastGestureRotate=0;f.mousedown=function(b){this.lastPoint=b.p};f.dblclick=function(b){this.center();this.repaint()};f.drag=function(b){if(!this.lastPoint.multi){if(q.ALT){var d=new n.Point(b.p.x,b.p.y);d.sub(this.lastPoint);for(let a=0,b=this.molecules.length;a<b;a++){var f=this.molecules[a];for(let a=
0,b=f.atoms.length;a<b;a++)f.atoms[a].add(d);f.check()}for(let a=0,b=this.shapes.length;a<b;a++){f=this.shapes[a].getPoints();for(let a=0,b=f.length;a<b;a++)f[a].add(d)}this.lastPoint=b.p}else if(!0===this.rotate3D){d=r.max(this.width/4,this.height/4);f=(b.p.x-this.lastPoint.x)/d*this.rotationMultMod;var a=-(b.p.y-this.lastPoint.y)/d*this.rotationMultMod;d=[];e.identity(d);e.rotate(d,a,[1,0,0]);e.rotate(d,f,[0,1,0]);for(let g=0,h=this.molecules.length;g<h;g++){f=this.molecules[g];for(let b=0,g=f.atoms.length;b<
g;b++){a=f.atoms[b];let g=[a.x-this.width/2,a.y-this.height/2,a.z];e.multiplyVec3(d,g);a.x=g[0]+this.width/2;a.y=g[1]+this.height/2;a.z=g[2]}for(let a=0,b=f.rings.length;a<b;a++)f.rings[a].center=f.rings[a].getCenter();this.lastPoint=b.p;this.styles.atoms_display&&this.styles.atoms_circles_2D&&f.sortAtomsByZ();this.styles.bonds_display&&this.styles.bonds_clearOverlaps_2D&&f.sortBondsByZ()}}else f=new n.Point(this.width/2,this.height/2),d=f.angle(this.lastPoint),f=f.angle(b.p),this.styles.rotateAngle-=
f-d,this.lastPoint=b.p;this.repaint()}};f.mousewheel=function(b,d){this.styles.scale+=d/50;.01>this.styles.scale&&(this.styles.scale=.01);this.repaint()};f.multitouchmove=function(b,d){if(2===d)if(this.lastPoint.multi){d=new n.Point(b.p.x,b.p.y);d.sub(this.lastPoint);for(let a=0,b=this.molecules.length;a<b;a++){var e=this.molecules[a];for(let a=0,b=e.atoms.length;a<b;a++)e.atoms[a].add(d);e.check()}for(let a=0,b=this.shapes.length;a<b;a++){e=this.shapes[a].getPoints();for(let a=0,b=e.length;a<b;a++)e[a].add(d)}this.lastPoint=
b.p;this.lastPoint.multi=!0;this.repaint()}else this.lastPoint=b.p,this.lastPoint.multi=!0};f.gesturechange=function(b){0!==b.originalEvent.scale-this.lastPinchScale&&(this.styles.scale*=b.originalEvent.scale/this.lastPinchScale,.01>this.styles.scale&&(this.styles.scale=.01),this.lastPinchScale=b.originalEvent.scale);if(0!==this.lastGestureRotate-b.originalEvent.rotation){let d=(this.lastGestureRotate-b.originalEvent.rotation)/180*r.PI,e=new n.Point(this.width/2,this.height/2);for(let a=0,b=this.molecules.length;a<
b;a++){let b=this.molecules[a];for(let a=0,f=b.atoms.length;a<f;a++){let f=b.atoms[a],g=e.distance(f),h=e.angle(f)+d;f.x=e.x+g*r.cos(h);f.y=e.y-g*r.sin(h)}b.check()}this.lastGestureRotate=b.originalEvent.rotation}this.repaint()};f.gestureend=function(b){this.lastPinchScale=1;this.lastGestureRotate=0}})(ChemDoodle,ChemDoodle.monitor,ChemDoodle.structures,Math,ChemDoodle.lib.mat4);(function(f,q){f.ViewerCanvas=function(f,q,e){f&&this.create(f,q,e)};f.ViewerCanvas.prototype=new f._Canvas})(ChemDoodle);
(function(f,q,n){f._SpectrumCanvas=function(f,e,k){f&&this.create(f,e,k)};f=f._SpectrumCanvas.prototype=new f._Canvas;f.spectrum=n;f.emptyMessage="No Spectrum Loaded or Recognized";f.loadMolecule=n;f.getMolecule=n;f.innerRepaint=function(f){this.spectrum&&0<this.spectrum.data.length?this.spectrum.draw(f,this.styles,this.width,this.height):this.emptyMessage&&(f.fillStyle="#737683",f.textAlign="center",f.textBaseline="middle",f.font="18px Helvetica, Verdana, Arial, Sans-serif",f.fillText(this.emptyMessage,
this.width/2,this.height/2))};f.loadSpectrum=function(f){this.spectrum=f;this.repaint()};f.getSpectrum=function(){return this.spectrum};f.getSpectrumCoordinates=function(f,e){return spectrum.getInternalCoordinates(f,e,this.width,this.height)}})(ChemDoodle,document);(function(f,q){f.ObserverCanvas=function(f,q,e){f&&this.create(f,q,e)};f.ObserverCanvas.prototype=new f._SpectrumCanvas})(ChemDoodle);
(function(f,q){f.OverlayCanvas=function(f,q,e){f&&this.create(f,q,e)};f=f.OverlayCanvas.prototype=new f._SpectrumCanvas;f.overlaySpectra=[];f.superRepaint=f.innerRepaint;f.innerRepaint=function(f){this.superRepaint(f);if(this.spectrum&&0<this.spectrum.data.length)for(let n=0,e=this.overlaySpectra.length;n<e;n++){let e=this.overlaySpectra[n];e&&0<e.data.length&&(e.minX=this.spectrum.minX,e.maxX=this.spectrum.maxX,e.drawPlot(f,this.styles,this.width,this.height,this.spectrum.memory.offsetTop,this.spectrum.memory.offsetLeft,
this.spectrum.memory.offsetBottom))}};f.addSpectrum=function(f){this.spectrum?this.overlaySpectra.push(f):this.spectrum=f}})(ChemDoodle);
(function(f,q,n,r){f.PerspectiveCanvas=function(e,b,d){e&&this.create(e,b,d)};let e=f.PerspectiveCanvas.prototype=new f._SpectrumCanvas;e.dragRange=r;e.rescaleYAxisOnZoom=!0;e.lastPinchScale=1;e.mousedown=function(e){this.dragRange=new f.structures.Point(e.p.x,e.p.x)};e.mouseup=function(e){this.dragRange&&this.dragRange.x!==this.dragRange.y&&(this.dragRange.multi||(e=this.spectrum.zoom(this.dragRange.x,e.p.x,this.width,this.rescaleYAxisOnZoom),this.rescaleYAxisOnZoom&&(this.styles.scale=e)),this.dragRange=
r,this.repaint())};e.drag=function(e){this.dragRange&&(this.dragRange.multi?this.dragRange=r:(q.SHIFT&&(this.spectrum.translate(e.p.x-this.dragRange.x,this.width),this.dragRange.x=e.p.x),this.dragRange.y=e.p.x),this.repaint())};e.drawChildExtras=function(e){if(this.dragRange){var b=n.min(this.dragRange.x,this.dragRange.y);let d=n.max(this.dragRange.x,this.dragRange.y);e.strokeStyle="gray";e.lineStyle=1;e.beginPath();for(e.moveTo(b,this.height/2);b<=d;b++)5>b%10?e.lineTo(b,n.round(this.height/2)):
e.moveTo(b,n.round(this.height/2));e.stroke()}};e.mousewheel=function(e,b){this.styles.scale-=b/10;.01>this.styles.scale&&(this.styles.scale=.01);this.repaint()};e.dblclick=function(e){this.spectrum.setup();this.styles.scale=1;this.repaint()};e.multitouchmove=function(e,b){2===b&&(this.dragRange&&this.dragRange.multi?(this.spectrum.translate(e.p.x-this.dragRange.x,this.width),this.dragRange.x=e.p.x,this.dragRange.y=e.p.x,this.repaint()):(this.dragRange=new f.structures.Point(e.p.x,e.p.x),this.dragRange.multi=
!0))};e.gesturechange=function(e){this.styles.scale*=e.originalEvent.scale/this.lastPinchScale;.01>this.styles.scale&&(this.styles.scale=.01);this.lastPinchScale=e.originalEvent.scale;this.repaint()};e.gestureend=function(e){this.lastPinchScale=1}})(ChemDoodle,ChemDoodle.monitor,Math);
(function(f,q,n,r){f.SeekerCanvas=function(e,b,d,f){e&&this.create(e,b,d);this.seekType=f};let e=f.SeekerCanvas.prototype=new f._SpectrumCanvas;e.superRepaint=e.innerRepaint;e.innerRepaint=function(e){this.superRepaint(e);if(this.spectrum&&0<this.spectrum.data.length&&this.p){if(this.seekType===f.SeekerCanvas.SEEK_POINTER){var b=this.p;var d=this.spectrum.getInternalCoordinates(b.x,b.y)}else if(this.seekType===f.SeekerCanvas.SEEK_PLOT||this.seekType===f.SeekerCanvas.SEEK_PEAK){d=this.seekType===f.SeekerCanvas.SEEK_PLOT?
this.spectrum.getClosestPlotInternalCoordinates(this.p.x):this.spectrum.getClosestPeakInternalCoordinates(this.p.x);if(!d)return;b={x:this.spectrum.getTransformedX(d.x,this.styles,this.width,this.spectrum.memory.offsetLeft),y:this.spectrum.getTransformedY(d.y/100,this.styles,this.height,this.spectrum.memory.offsetBottom,this.spectrum.memory.offsetTop)}}e.fillStyle="white";e.strokeStyle=this.styles.plots_color;e.lineWidth=this.styles.plots_width;e.beginPath();e.arc(b.x,b.y,3,0,2*n.PI,!1);e.fill();
e.stroke();e.font=q.getFontString(this.styles.text_font_size,this.styles.text_font_families);e.textAlign="left";e.textBaseline="bottom";d="x:"+d.x.toFixed(3)+", y:"+d.y.toFixed(3);let h=b.x+3,a=e.measureText(d).width;h+a>this.width-2&&(h-=6+a);b=b.y;0>b-this.styles.text_font_size-2&&(b+=this.styles.text_font_size);e.fillRect(h,b-this.styles.text_font_size,a,this.styles.text_font_size);e.fillStyle="black";e.fillText(d,h,b)}};e.mouseout=function(e){this.p=r;this.repaint()};e.mousemove=function(e){this.p=
{x:e.p.x-2,y:e.p.y-3};this.repaint()};e.touchstart=function(e){this.mousemove(e)};e.touchmove=function(e){this.mousemove(e)};e.touchend=function(e){this.mouseout(e)};f.SeekerCanvas.SEEK_POINTER="pointer";f.SeekerCanvas.SEEK_PLOT="plot";f.SeekerCanvas.SEEK_PEAK="peak"})(ChemDoodle,ChemDoodle.extensions,Math);
(function(f,q,n,r,e,k,b,d,h,a,g,l,v,m){f._Canvas3D=function(a,b,d){a&&this.create(a,b,d)};a=f._Canvas3D.prototype=new f._Canvas;let x=f._Canvas.prototype;a.rotationMatrix=m;a.lastPoint=m;a.emptyMessage="WebGL is Unavailable!";a.lastPinchScale=1;a.lastGestureRotate=0;a.afterLoadContent=function(){var a=new n.Bounds;for(let b=0,c=this.molecules.length;b<c;b++)a.expand(this.molecules[b].getBounds3D());var d=g.dist([a.maxX,a.maxY,a.maxZ],[a.minX,a.minY,a.minZ])/2+1.5;Infinity===d&&(d=10);this.maxDimension=
b.max(a.maxX-a.minX,a.maxY-a.minY);a=b.min(179.9,b.max(this.styles.projectionPerspectiveVerticalFieldOfView_3D,.1));var e=a/360*b.PI,f=b.tan(e)/.8;f=d/f;let c=this.width/this.height;this.camera.fieldOfView=a;this.camera.near=f-d;this.camera.far=f+d;this.camera.aspect=c;h.translate(h.identity(this.camera.viewMatrix),[0,0,-f]);e=d/b.tan(e);this.lighting.camera.fieldOfView=a;this.lighting.camera.near=e-d;this.lighting.camera.far=e+d;this.lighting.updateView();this.setupScene()};a.renderDepthMap=function(){if(this.styles.shadow_3D&&
e.DepthShader){let a=this.gl.isEnabled(this.gl.CULL_FACE);a||this.gl.enable(this.gl.CULL_FACE);this.depthShader.useShaderProgram(this.gl);let b=this.gl.getParameter(this.gl.COLOR_CLEAR_VALUE);this.gl.clearColor(1,1,1,0);this.lightDepthMapFramebuffer.bind(this.gl,this.shadowTextureSize,this.shadowTextureSize);this.gl.clear(this.gl.COLOR_BUFFER_BIT|this.gl.DEPTH_BUFFER_BIT);this.depthShader.setProjectionMatrix(this.gl,this.lighting.camera.projectionMatrix);this.depthShader.enableAttribsArray(this.gl);
for(let a=0,b=this.molecules.length;a<b;a++)this.molecules[a].render(this.gl,this.styles);this.gl.flush();this.depthShader.disableAttribsArray(this.gl);this.gl.bindFramebuffer(this.gl.FRAMEBUFFER,null);this.gl.clearColor(b[0],b[1],b[2],b[3]);a||this.gl.disable(this.gl.CULL_FACE)}};a.renderExtras=function(){this.phongShader.useShaderProgram(this.gl);this.phongShader.enableAttribsArray(this.gl);var a=[];for(let b=0,d=this.shapes.length;b<d;b++){let d=this.shapes[b];d instanceof e._Surface&&(!d.styles&&
1!==this.styles.surfaces_alpha||d.styles&&1!==d.styles.surfaces_alpha)?a.push(d):d.render(this.gl,this.styles)}if(0!==a.length){this.gl.blendFunc(this.gl.SRC_ALPHA,this.gl.ONE_MINUS_SRC_ALPHA);this.gl.enable(this.gl.BLEND);this.gl.depthMask(!1);for(let b=0,d=a.length;b<d;b++)a[b].render(this.gl,this.styles);this.gl.depthMask(!0);this.gl.disable(this.gl.BLEND);this.gl.blendFuncSeparate(this.gl.SRC_ALPHA,this.gl.ONE_MINUS_SRC_ALPHA,this.gl.ONE,this.gl.ONE_MINUS_SRC_ALPHA)}this.phongShader.setShadow(this.gl,
!1);this.phongShader.setFogMode(this.gl,0);this.phongShader.setFlatColor(this.gl,!1);this.styles.compass_display&&(this.phongShader.setLightDirection(this.gl,[0,0,-1]),this.compass.render(this.gl,this.styles));this.phongShader.disableAttribsArray(this.gl);this.gl.flush();this.gl.enable(this.gl.BLEND);this.gl.depthMask(!1);this.labelShader.useShaderProgram(this.gl);this.labelShader.setMatrixUniforms(this.gl,this.gl.modelViewMatrix);this.labelShader.setProjectionMatrix(this.gl,this.camera.projectionMatrix);
this.labelShader.setDimension(this.gl,this.gl.canvas.clientWidth,this.gl.canvas.clientHeight);this.labelShader.enableAttribsArray(this.gl);this.styles.atoms_displayLabels_3D&&this.label3D.render(this.gl,this.styles,this.getMolecules());if(this.styles.measurement_displayText_3D)for(let b=0,d=this.shapes.length;b<d;b++)a=this.shapes[b],a.renderText&&a.renderText(this.gl,this.styles);this.styles.compass_display&&this.styles.compass_displayText_3D&&this.compass.renderAxis(this.gl);this.labelShader.disableAttribsArray(this.gl);
this.gl.disable(this.gl.BLEND);this.gl.depthMask(!0);this.gl.flush();this.drawChildExtras&&this.drawChildExtras(this.gl);this.gl.flush()};a.renderColor=function(){this.phongShader.useShaderProgram(this.gl);this.gl.uniform1i(this.phongShader.shadowDepthSampleUniform,0);this.gl.activeTexture(this.gl.TEXTURE0);this.gl.bindTexture(this.gl.TEXTURE_2D,this.lightDepthMapTexture.texture);this.phongShader.setProjectionMatrix(this.gl,this.camera.projectionMatrix);this.phongShader.setShadow(this.gl,this.styles.shadow_3D);
this.phongShader.setFlatColor(this.gl,this.styles.flat_color_3D);this.phongShader.setGammaCorrection(this.gl,this.styles.gammaCorrection_3D);this.phongShader.setShadowTextureSize(this.gl,this.shadowTextureSize,this.shadowTextureSize);this.phongShader.setShadowIntensity(this.gl,this.styles.shadow_intensity_3D);this.phongShader.setFogMode(this.gl,this.styles.fog_mode_3D);this.phongShader.setFogColor(this.gl,this.fogging.colorRGB);this.phongShader.setFogStart(this.gl,this.fogging.fogStart);this.phongShader.setFogEnd(this.gl,
this.fogging.fogEnd);this.phongShader.setFogDensity(this.gl,this.fogging.density);this.phongShader.setLightProjectionMatrix(this.gl,this.lighting.camera.projectionMatrix);this.phongShader.setLightDiffuseColor(this.gl,this.lighting.diffuseRGB);this.phongShader.setLightSpecularColor(this.gl,this.lighting.specularRGB);this.phongShader.setLightDirection(this.gl,this.lighting.direction);this.phongShader.enableAttribsArray(this.gl);for(let a=0,b=this.molecules.length;a<b;a++)this.molecules[a].render(this.gl,
this.styles);this.phongShader.disableAttribsArray(this.gl);this.gl.flush()};a.renderPosition=function(){this.positionShader.useShaderProgram(this.gl);this.positionShader.setProjectionMatrix(this.gl,this.camera.projectionMatrix);this.positionShader.enableAttribsArray(this.gl);for(let a=0,b=this.molecules.length;a<b;a++)this.molecules[a].render(this.gl,this.styles);this.positionShader.disableAttribsArray(this.gl);this.gl.flush()};a.renderNormal=function(){this.normalShader.useShaderProgram(this.gl);
this.normalShader.setProjectionMatrix(this.gl,this.camera.projectionMatrix);this.normalShader.enableAttribsArray(this.gl);for(let a=0,b=this.molecules.length;a<b;a++)this.molecules[a].render(this.gl,this.styles);this.normalShader.disableAttribsArray(this.gl);this.gl.flush()};a.renderSSAO=function(){this.ssaoShader.useShaderProgram(this.gl);this.ssaoShader.setProjectionMatrix(this.gl,this.camera.projectionMatrix);this.ssaoShader.setSampleKernel(this.gl,this.ssao.sampleKernel);this.ssaoShader.setKernelRadius(this.gl,
this.styles.ssao_kernel_radius);this.ssaoShader.setPower(this.gl,this.styles.ssao_power);this.ssaoShader.setGbufferTextureSize(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.gl.uniform1i(this.ssaoShader.positionSampleUniform,0);this.gl.uniform1i(this.ssaoShader.normalSampleUniform,1);this.gl.uniform1i(this.ssaoShader.noiseSampleUniform,2);this.gl.activeTexture(this.gl.TEXTURE0);this.gl.bindTexture(this.gl.TEXTURE_2D,this.positionTexture.texture);this.gl.activeTexture(this.gl.TEXTURE1);
this.gl.bindTexture(this.gl.TEXTURE_2D,this.normalTexture.texture);this.gl.activeTexture(this.gl.TEXTURE2);this.gl.bindTexture(this.gl.TEXTURE_2D,this.ssao.noiseTexture);this.gl.activeTexture(this.gl.TEXTURE0);this.ssaoShader.enableAttribsArray(this.gl);this.gl.quadBuffer.bindBuffers(this.gl);this.gl.drawArrays(this.gl.TRIANGLE_STRIP,0,this.gl.quadBuffer.vertexPositionBuffer.numItems);this.ssaoShader.disableAttribsArray(this.gl);this.gl.flush();this.ssaoFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,
this.gl.drawingBufferHeight);this.gl.clear(this.gl.COLOR_BUFFER_BIT);this.ssaoBlurShader.useShaderProgram(this.gl);this.ssaoBlurShader.setGbufferTextureSize(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.gl.uniform1i(this.ssaoBlurShader.aoSampleUniform,0);this.gl.uniform1i(this.ssaoBlurShader.depthSampleUniform,1);this.gl.activeTexture(this.gl.TEXTURE0);this.gl.bindTexture(this.gl.TEXTURE_2D,this.imageTexture.texture);this.gl.activeTexture(this.gl.TEXTURE1);this.gl.bindTexture(this.gl.TEXTURE_2D,
this.depthTexture.texture);this.gl.activeTexture(this.gl.TEXTURE0);this.ssaoBlurShader.enableAttribsArray(this.gl);this.gl.quadBuffer.bindBuffers(this.gl);this.gl.drawArrays(this.gl.TRIANGLE_STRIP,0,this.gl.quadBuffer.vertexPositionBuffer.numItems);this.ssaoBlurShader.disableAttribsArray(this.gl);this.gl.activeTexture(this.gl.TEXTURE0);this.gl.flush()};a.renderOutline=function(){this.outlineShader.useShaderProgram(this.gl);this.outlineShader.setGbufferTextureSize(this.gl,this.gl.drawingBufferWidth,
this.gl.drawingBufferHeight);this.outlineShader.setNormalThreshold(this.gl,this.styles.outline_normal_threshold);this.outlineShader.setDepthThreshold(this.gl,this.styles.outline_depth_threshold);this.outlineShader.setThickness(this.gl,this.styles.outline_thickness);this.gl.uniform1i(this.outlineShader.normalSampleUniform,0);this.gl.uniform1i(this.outlineShader.depthSampleUniform,1);this.gl.activeTexture(this.gl.TEXTURE0);this.gl.bindTexture(this.gl.TEXTURE_2D,this.normalTexture.texture);this.gl.activeTexture(this.gl.TEXTURE1);
this.gl.bindTexture(this.gl.TEXTURE_2D,this.depthTexture.texture);this.gl.activeTexture(this.gl.TEXTURE0);this.outlineShader.enableAttribsArray(this.gl);this.gl.quadBuffer.bindBuffers(this.gl);this.gl.drawArrays(this.gl.TRIANGLE_STRIP,0,this.gl.quadBuffer.vertexPositionBuffer.numItems);this.outlineShader.disableAttribsArray(this.gl);this.gl.flush()};a.deferredRender=function(){let a=this.gl.getParameter(this.gl.COLOR_CLEAR_VALUE);this.gl.clearColor(0,0,0,0);this.colorFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,
this.gl.drawingBufferHeight);this.gl.clear(this.gl.COLOR_BUFFER_BIT|this.gl.DEPTH_BUFFER_BIT);this.renderColor();this.positionFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.gl.clear(this.gl.COLOR_BUFFER_BIT|this.gl.DEPTH_BUFFER_BIT);this.renderPosition();this.normalFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.gl.clear(this.gl.COLOR_BUFFER_BIT|this.gl.DEPTH_BUFFER_BIT);this.renderNormal();this.styles.ssao_3D&&e.SSAOShader?
(this.quadFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight),this.gl.clear(this.gl.COLOR_BUFFER_BIT),this.renderSSAO()):(this.ssaoFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight),this.gl.clearColor(1,1,1,1),this.gl.clear(this.gl.COLOR_BUFFER_BIT));this.outlineFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.gl.clearColor(1,1,1,1);this.gl.clear(this.gl.COLOR_BUFFER_BIT);this.styles.outline_3D&&this.renderOutline();
this.gl.clearColor(a[0],a[1],a[2],a[3]);this.quadFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.gl.clear(this.gl.COLOR_BUFFER_BIT);this.lightingShader.useShaderProgram(this.gl);this.gl.uniform1i(this.lightingShader.positionSampleUniform,0);this.gl.uniform1i(this.lightingShader.colorSampleUniform,1);this.gl.uniform1i(this.lightingShader.ssaoSampleUniform,2);this.gl.uniform1i(this.lightingShader.outlineSampleUniform,3);this.gl.activeTexture(this.gl.TEXTURE0);this.gl.bindTexture(this.gl.TEXTURE_2D,
this.positionTexture.texture);this.gl.activeTexture(this.gl.TEXTURE1);this.gl.bindTexture(this.gl.TEXTURE_2D,this.colorTexture.texture);this.gl.activeTexture(this.gl.TEXTURE2);this.gl.bindTexture(this.gl.TEXTURE_2D,this.ssaoTexture.texture);this.gl.activeTexture(this.gl.TEXTURE3);this.gl.bindTexture(this.gl.TEXTURE_2D,this.outlineTexture.texture);this.gl.activeTexture(this.gl.TEXTURE0);this.lightingShader.enableAttribsArray(this.gl);this.gl.quadBuffer.bindBuffers(this.gl);this.gl.drawArrays(this.gl.TRIANGLE_STRIP,
0,this.gl.quadBuffer.vertexPositionBuffer.numItems);this.lightingShader.disableAttribsArray(this.gl);this.gl.flush();this.fxaaFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.gl.clear(this.gl.COLOR_BUFFER_BIT|this.gl.DEPTH_BUFFER_BIT);this.gl.viewport(0,0,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.gl.bindTexture(this.gl.TEXTURE_2D,this.imageTexture.texture);this.fxaaShader.useShaderProgram(this.gl);this.fxaaShader.setBuffersize(this.gl,this.gl.drawingBufferWidth,
this.gl.drawingBufferHeight);this.fxaaShader.setAntialias(this.gl,this.styles.antialias_3D);this.fxaaShader.setEdgeThreshold(this.gl,this.styles.fxaa_edgeThreshold);this.fxaaShader.setEdgeThresholdMin(this.gl,this.styles.fxaa_edgeThresholdMin);this.fxaaShader.setSearchSteps(this.gl,this.styles.fxaa_searchSteps);this.fxaaShader.setSearchThreshold(this.gl,this.styles.fxaa_searchThreshold);this.fxaaShader.setSubpixCap(this.gl,this.styles.fxaa_subpixCap);this.fxaaShader.setSubpixTrim(this.gl,this.styles.fxaa_subpixTrim);
this.fxaaShader.enableAttribsArray(this.gl);this.gl.quadBuffer.bindBuffers(this.gl);this.gl.drawArrays(this.gl.TRIANGLE_STRIP,0,this.gl.quadBuffer.vertexPositionBuffer.numItems);this.fxaaShader.disableAttribsArray(this.gl);this.gl.flush();this.finalFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.renderExtras();this.gl.clearColor(a[0],a[1],a[2],a[3]);this.gl.bindFramebuffer(this.gl.FRAMEBUFFER,null);this.gl.clear(this.gl.COLOR_BUFFER_BIT|this.gl.DEPTH_BUFFER_BIT);
this.gl.viewport(0,0,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.gl.bindTexture(this.gl.TEXTURE_2D,this.fxaaTexture.texture);this.quadShader.useShaderProgram(this.gl);this.quadShader.enableAttribsArray(this.gl);this.gl.quadBuffer.bindBuffers(this.gl);this.gl.drawArrays(this.gl.TRIANGLE_STRIP,0,this.gl.quadBuffer.vertexPositionBuffer.numItems);this.quadShader.disableAttribsArray(this.gl);this.gl.flush()};a.forwardRender=function(){this.gl.bindFramebuffer(this.gl.FRAMEBUFFER,null);
this.gl.clear(this.gl.COLOR_BUFFER_BIT|this.gl.DEPTH_BUFFER_BIT);this.gl.viewport(0,0,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.renderColor();this.renderExtras()};a.repaint=function(){this.gl&&(this.gl.lightViewMatrix=h.multiply(this.lighting.camera.viewMatrix,this.rotationMatrix,[]),this.gl.rotationMatrix=this.rotationMatrix,this.gl.modelViewMatrix=this.gl.lightViewMatrix,this.renderDepthMap(),this.gl.modelViewMatrix=h.multiply(this.camera.viewMatrix,this.rotationMatrix,[]),this.isSupportDeferred()&&
(this.styles.ssao_3D||this.styles.outline_3D)?this.deferredRender():this.forwardRender())};a.pick=function(a,b,d,e){if(this.gl){let c=this.height-b;1!==this.pixelRatio&&(a*=this.pixelRatio,c*=this.pixelRatio);h.multiply(this.camera.viewMatrix,this.rotationMatrix,this.gl.modelViewMatrix);this.gl.rotationMatrix=this.rotationMatrix;this.pickShader.useShaderProgram(this.gl);b=this.gl.getParameter(this.gl.COLOR_CLEAR_VALUE);this.gl.clearColor(1,1,1,0);this.pickerFramebuffer.bind(this.gl,this.gl.drawingBufferWidth,
this.gl.drawingBufferHeight);this.gl.clear(this.gl.COLOR_BUFFER_BIT|this.gl.DEPTH_BUFFER_BIT);this.pickShader.setProjectionMatrix(this.gl,this.camera.projectionMatrix);this.pickShader.enableAttribsArray(this.gl);let f=[];for(let a=0,b=this.molecules.length;a<b;a++)this.molecules[a].renderPickFrame(this.gl,this.styles,f,d,e);this.pickShader.disableAttribsArray(this.gl);this.gl.flush();d=new Uint8Array(4);this.gl.readPixels(a-2,c+2,1,1,this.gl.RGBA,this.gl.UNSIGNED_BYTE,d);e=m;0<d[3]&&(e=f[d[2]|d[1]<<
8|d[0]<<16]);this.gl.bindFramebuffer(this.gl.FRAMEBUFFER,null);this.gl.clearColor(b[0],b[1],b[2],b[3]);return e}return m};a.center=function(){let a=new r.Atom;for(let b=0,d=this.molecules.length;b<d;b++)a.add3D(this.molecules[b].getCenter3D());a.x/=this.molecules.length;a.y/=this.molecules.length;for(let b=0,d=this.molecules.length;b<d;b++){let d=this.molecules[b];for(let b=0,e=d.atoms.length;b<e;b++)d.atoms[b].sub3D(a);if(d.chains&&d.fromJSON)for(let b=0,e=d.chains.length;b<e;b++){let c=d.chains[b];
for(let b=0,d=c.length;b<d;b++){let d=c[b];d.cp1.sub3D(a);d.cp2.sub3D(a);d.cp3&&(d.cp3.sub3D(a),d.cp4.sub3D(a),d.cp5.sub3D(a))}}}};a.isSupportDeferred=function(){return this.gl.textureFloatExt&&this.gl.depthTextureExt};a.create=function(a,b,f){x.create.call(this,a,b,f);try{let a=d.getElementById(this.id);this.gl=a.getContext("webgl");this.gl||(this.gl=a.getContext("experimental-webgl"))}catch(y){}this.gl?(1!==this.pixelRatio&&this.gl.canvas.width===this.width&&(this.gl.canvas.style.width=this.width+
"px",this.gl.canvas.style.height=this.height+"px",this.gl.canvas.width=this.width*this.pixelRatio,this.gl.canvas.height=this.height*this.pixelRatio),this.gl.enable(this.gl.DEPTH_TEST),this.gl.depthFunc(this.gl.LEQUAL),this.gl.blendFuncSeparate(this.gl.SRC_ALPHA,this.gl.ONE_MINUS_SRC_ALPHA,this.gl.ONE,this.gl.ONE_MINUS_SRC_ALPHA),this.gl.clearDepth(1),this.shadowTextureSize=1024,this.rotationMatrix=h.identity([]),this.camera=new e.Camera,this.label3D=new e.Label,this.lighting=new e.Light(this.styles.lightDiffuseColor_3D,
this.styles.lightSpecularColor_3D,this.styles.lightDirection_3D),this.fogging=new e.Fog(this.styles.fog_color_3D||this.styles.backgroundColor,this.styles.fog_start_3D,this.styles.fog_end_3D,this.styles.fog_density_3D),this.gl.depthTextureExt=this.gl.getExtension("WEBGL_depth_texture")||this.gl.getExtension("WEBKIT_WEBGL_depth_texture")||this.gl.getExtension("MOZ_WEBGL_depth_texture"),this.gl.textureFloatExt=this.gl.getExtension("OES_texture_float")||this.gl.getExtension("WEBKIT_OES_texture_float")||
this.gl.getExtension("MOZ_OES_texture_float"),this.ssao=new e.SSAO,this.pickerColorTexture=new e.Texture,this.pickerColorTexture.init(this.gl,this.gl.UNSIGNED_BYTE,this.gl.RGBA,this.gl.RGBA),this.pickerDepthRenderbuffer=new e.Renderbuffer,this.pickerDepthRenderbuffer.init(this.gl,this.gl.DEPTH_COMPONENT16),this.pickerFramebuffer=new e.Framebuffer,this.pickerFramebuffer.init(this.gl),this.pickerFramebuffer.setColorTexture(this.gl,this.pickerColorTexture.texture),this.pickerFramebuffer.setDepthRenderbuffer(this.gl,
this.pickerDepthRenderbuffer.renderbuffer),this.lightDepthMapTexture=new e.Texture,this.lightDepthMapRenderbuffer=new e.Renderbuffer,this.lightDepthMapFramebuffer=new e.Framebuffer,this.lightDepthMapFramebuffer.init(this.gl),this.gl.depthTextureExt?(this.lightDepthMapTexture.init(this.gl,this.gl.UNSIGNED_SHORT,this.gl.DEPTH_COMPONENT),this.lightDepthMapRenderbuffer.init(this.gl,this.gl.RGBA4),this.lightDepthMapFramebuffer.setColorRenderbuffer(this.gl,this.lightDepthMapRenderbuffer.renderbuffer),this.lightDepthMapFramebuffer.setDepthTexture(this.gl,
this.lightDepthMapTexture.texture)):(this.lightDepthMapTexture.init(this.gl,this.gl.UNSIGNED_BYTE,this.gl.RGBA,this.gl.RGBA),this.lightDepthMapRenderbuffer.init(this.gl,this.gl.DEPTH_COMPONENT16),this.lightDepthMapFramebuffer.setColorTexture(this.gl,this.lightDepthMapTexture.texture),this.lightDepthMapFramebuffer.setDepthRenderbuffer(this.gl,this.lightDepthMapRenderbuffer.renderbuffer)),this.isSupportDeferred()&&(this.depthTexture=new e.Texture,this.depthTexture.init(this.gl,this.gl.UNSIGNED_SHORT,
this.gl.DEPTH_COMPONENT),this.colorTexture=new e.Texture,this.colorTexture.init(this.gl,this.gl.UNSIGNED_BYTE,this.gl.RGBA),this.positionTexture=new e.Texture,this.positionTexture.init(this.gl,this.gl.FLOAT,this.gl.RGBA),this.normalTexture=new e.Texture,this.normalTexture.init(this.gl,this.gl.FLOAT,this.gl.RGBA),this.ssaoTexture=new e.Texture,this.ssaoTexture.init(this.gl,this.gl.FLOAT,this.gl.RGBA),this.outlineTexture=new e.Texture,this.outlineTexture.init(this.gl,this.gl.UNSIGNED_BYTE,this.gl.RGBA),
this.fxaaTexture=new e.Texture,this.fxaaTexture.init(this.gl,this.gl.FLOAT,this.gl.RGBA),this.imageTexture=new e.Texture,this.imageTexture.init(this.gl,this.gl.FLOAT,this.gl.RGBA),this.colorFramebuffer=new e.Framebuffer,this.colorFramebuffer.init(this.gl),this.colorFramebuffer.setColorTexture(this.gl,this.colorTexture.texture),this.colorFramebuffer.setDepthTexture(this.gl,this.depthTexture.texture),this.normalFramebuffer=new e.Framebuffer,this.normalFramebuffer.init(this.gl),this.normalFramebuffer.setColorTexture(this.gl,
this.normalTexture.texture),this.normalFramebuffer.setDepthTexture(this.gl,this.depthTexture.texture),this.positionFramebuffer=new e.Framebuffer,this.positionFramebuffer.init(this.gl),this.positionFramebuffer.setColorTexture(this.gl,this.positionTexture.texture),this.positionFramebuffer.setDepthTexture(this.gl,this.depthTexture.texture),this.ssaoFramebuffer=new e.Framebuffer,this.ssaoFramebuffer.init(this.gl),this.ssaoFramebuffer.setColorTexture(this.gl,this.ssaoTexture.texture),this.outlineFramebuffer=
new e.Framebuffer,this.outlineFramebuffer.init(this.gl),this.outlineFramebuffer.setColorTexture(this.gl,this.outlineTexture.texture),this.fxaaFramebuffer=new e.Framebuffer,this.fxaaFramebuffer.init(this.gl),this.fxaaFramebuffer.setColorTexture(this.gl,this.fxaaTexture.texture),this.quadFramebuffer=new e.Framebuffer,this.quadFramebuffer.init(this.gl),this.quadFramebuffer.setColorTexture(this.gl,this.imageTexture.texture),this.finalFramebuffer=new e.Framebuffer,this.finalFramebuffer.init(this.gl),this.finalFramebuffer.setColorTexture(this.gl,
this.fxaaTexture.texture),this.finalFramebuffer.setDepthTexture(this.gl,this.depthTexture.texture),this.normalShader=new e.NormalShader,this.normalShader.init(this.gl),this.positionShader=new e.PositionShader,this.positionShader.init(this.gl),e.SSAOShader&&(this.ssaoShader=new e.SSAOShader,this.ssaoShader.init(this.gl),this.ssaoBlurShader=new e.SSAOBlurShader,this.ssaoBlurShader.init(this.gl)),this.outlineShader=new e.OutlineShader,this.outlineShader.init(this.gl),this.lightingShader=new e.LightingShader,
this.lightingShader.init(this.gl),this.fxaaShader=new e.FXAAShader,this.fxaaShader.init(this.gl),this.quadShader=new e.QuadShader,this.quadShader.init(this.gl)),this.labelShader=new e.LabelShader,this.labelShader.init(this.gl),this.pickShader=new e.PickShader,this.pickShader.init(this.gl),this.phongShader=new e.PhongShader,this.phongShader.init(this.gl),e.DepthShader&&(this.depthShader=new e.DepthShader,this.depthShader.init(this.gl)),this.textTextImage=new e.TextImage,this.textTextImage.init(this.gl),
this.gl.textImage=new e.TextImage,this.gl.textImage.init(this.gl),this.gl.textMesh=new e.TextMesh,this.gl.textMesh.init(this.gl),this.gl.material=new e.Material,this.setupScene()):this.displayMessage()};a.displayMessage=function(){var a=d.getElementById(this.id);a.getContext&&(a=a.getContext("2d"),this.styles.backgroundColor&&(a.fillStyle=this.styles.backgroundColor,a.fillRect(0,0,this.width,this.height)),this.emptyMessage&&(a.fillStyle="#737683",a.textAlign="center",a.textBaseline="middle",a.font=
"18px Helvetica, Verdana, Arial, Sans-serif",a.fillText(this.emptyMessage,this.width/2,this.height/2)))};a.renderText=function(a,b){let d={position:[],texCoord:[],translation:[]};this.textTextImage.pushVertexData(a,b,0,d);this.gl.textMesh.storeData(this.gl,d.position,d.texCoord,d.translation);this.textTextImage.useTexture(this.gl);this.gl.textMesh.render(this.gl)};a.setupScene=function(){if(this.gl){var a=l("#"+this.id),d=this.styles.backgroundColor?this.styles.backgroundColor:"transparent";a.css("background-color",
d);a="transparent"===d?[0,0,0,0]:n.getRGB(d,1);this.gl.clearColor(a[0],a[1],a[2],4==a.length?a[3]:1);this.styles.cullBackFace_3D?this.gl.enable(this.gl.CULL_FACE):this.gl.disable(this.gl.CULL_FACE);this.gl.sphereBuffer=new e.Sphere(1,this.styles.atoms_resolution_3D,this.styles.atoms_resolution_3D);this.gl.starBuffer=new e.Star;this.gl.cylinderBuffer=new e.Cylinder(1,1,this.styles.bonds_resolution_3D);this.gl.cylinderClosedBuffer=new e.Cylinder(1,1,this.styles.bonds_resolution_3D,!0);this.gl.boxBuffer=
new e.Box(1,1,1);this.gl.pillBuffer=new e.Pill(this.styles.bonds_pillDiameter_3D/2,this.styles.bonds_pillHeight_3D,this.styles.bonds_pillLatitudeResolution_3D,this.styles.bonds_pillLongitudeResolution_3D);this.gl.lineBuffer=new e.Line;this.gl.lineArrowBuffer=new e.LineArrow;this.gl.arrowBuffer=new e.Arrow(.3,this.styles.compass_resolution_3D);this.gl.quadBuffer=new e.Quad;this.gl.textImage.updateFont(this.gl,this.styles.text_font_size,this.styles.text_font_families,this.styles.text_font_bold,this.styles.text_font_italic,
this.styles.text_font_stroke_3D);this.lighting.lightScene(this.styles.lightDiffuseColor_3D,this.styles.lightSpecularColor_3D,this.styles.lightDirection_3D);this.fogging.fogScene(this.styles.fog_color_3D||this.styles.backgroundColor,this.styles.fog_start_3D,this.styles.fog_end_3D,this.styles.fog_density_3D);this.compass=new e.Compass(this.gl,this.styles);this.lightDepthMapTexture.setParameter(this.gl,this.shadowTextureSize,this.shadowTextureSize);this.lightDepthMapRenderbuffer.setParameter(this.gl,
this.shadowTextureSize,this.shadowTextureSize);this.pickerColorTexture.setParameter(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.pickerDepthRenderbuffer.setParameter(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight);this.isSupportDeferred()&&(this.depthTexture.setParameter(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight),this.colorTexture.setParameter(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight),this.imageTexture.setParameter(this.gl,
this.gl.drawingBufferWidth,this.gl.drawingBufferHeight),this.positionTexture.setParameter(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight),this.normalTexture.setParameter(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight),this.ssaoTexture.setParameter(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight),this.outlineTexture.setParameter(this.gl,this.gl.drawingBufferWidth,this.gl.drawingBufferHeight),this.fxaaTexture.setParameter(this.gl,this.gl.drawingBufferWidth,
this.gl.drawingBufferHeight),this.ssao.initSampleKernel(this.styles.ssao_kernel_samples),this.ssao.initNoiseTexture(this.gl));this.camera.updateProjectionMatrix(this.styles.projectionPerspective_3D);for(let f=0,l=this.molecules.length;f<l;f++)if(a=this.molecules[f],a.labelMesh instanceof e.TextMesh||(a.labelMesh=new e.TextMesh,a.labelMesh.init(this.gl)),a.chains){a.ribbons=[];a.cartoons=[];a.tubes=[];a.pipePlanks=[];for(let f=0,l=a.chains.length;f<l;f++){d=a.chains[f];for(let a=0,b=d.length-1;a<b;a++)d[a].Test=
a;var h=3<d.length&&k[d[3].name]&&"#BEA06E"===k[d[3].name].aminoColor;if(0<d.length&&!d[0].lineSegments){for(let a=0,b=d.length-1;a<b;a++)d[a].setup(d[a+1].cp1,h?1:this.styles.proteins_horizontalResolution);if(!h)for(let a=1,c=d.length-1;a<c;a++)q.vec3AngleFrom(d[a-1].D,d[a].D)>b.PI/2&&(d[a].guidePointsSmall.reverse(),d[a].guidePointsLarge.reverse(),g.scale(d[a].D,-1));for(let a=2,b=d.length-3;a<b;a++)d[a].computeLineSegments(d[a-2],d[a-1],d[a+1],!h,h?this.styles.nucleics_verticalResolution:this.styles.proteins_verticalResolution);
d.pop();d.pop();d.pop();d.shift();d.shift()}var m=n.hsl2rgb(1===l?.5:f/l,1,.5);m="rgb("+m[0]+","+m[1]+","+m[2]+")";d.chainColor=m;if(h)d=new e.Tube(d,this.styles.nucleics_tubeThickness,this.styles.nucleics_tubeResolution_3D),d.chainColor=m,a.tubes.push(d);else{h=new e.PipePlank(d,this.styles);a.pipePlanks.push(h);h=d.shift();var c={front:new e.Ribbon(d,this.styles.proteins_ribbonThickness,!1),back:new e.Ribbon(d,-this.styles.proteins_ribbonThickness,!1)};c.front.chainColor=m;c.back.chainColor=m;a.ribbons.push(c);
c={front:new e.Ribbon(d,this.styles.proteins_ribbonThickness,!0),back:new e.Ribbon(d,-this.styles.proteins_ribbonThickness,!0)};c.front.chainColor=m;c.back.chainColor=m;a.cartoons.push(c);d.unshift(h)}}}this.label3D.updateVerticesBuffer(this.gl,this.getMolecules(),this.styles);if(this instanceof f.MovieCanvas3D&&this.frames)for(let b=0,c=this.frames.length;b<c;b++){a=this.frames[b];for(let b=0,c=a.mols.length;b<c;b++)d=a.mols[b],d.labelMesh instanceof r.d3.TextMesh||(d.labelMesh=new r.d3.TextMesh,
d.labelMesh.init(this.gl));this.label3D.updateVerticesBuffer(this.gl,a.mols,this.styles)}}};a.updateScene=function(){this.camera.updateProjectionMatrix(this.styles.projectionPerspective_3D);this.lighting.lightScene(this.styles.lightDiffuseColor_3D,this.styles.lightSpecularColor_3D,this.styles.lightDirection_3D);this.fogging.fogScene(this.styles.fog_color_3D||this.styles.backgroundColor,this.styles.fog_start_3D,this.styles.fog_end_3D,this.styles.fog_density_3D);this.repaint()};a.mousedown=function(a){this.lastPoint=
a.p};a.mouseup=function(a){this.lastPoint=m};a.rightmousedown=function(a){this.lastPoint=a.p};a.drag=function(a){if(this.lastPoint){if(f.monitor.ALT){var d=new r.Point(a.p.x,a.p.y);d.sub(this.lastPoint);var e=b.tan(this.camera.fieldOfView/360*b.PI);e=this.height/2/this.camera.zoom/e;e=this.camera.focalLength()/e;h.translate(this.camera.viewMatrix,[d.x*e,-d.y*e,0])}else e=a.p.x-this.lastPoint.x,d=a.p.y-this.lastPoint.y,e=h.rotate(h.identity([]),e*b.PI/180,[0,1,0]),h.rotate(e,d*b.PI/180,[1,0,0]),this.rotationMatrix=
h.multiply(e,this.rotationMatrix);this.lastPoint=a.p;this.repaint()}};a.mousewheel=function(a,b){0<b?this.camera.zoomIn():this.camera.zoomOut();this.updateScene()};a.multitouchmove=function(a,d){if(2===d)if(this.lastPoint&&this.lastPoint.multi){d=new r.Point(a.p.x,a.p.y);d.sub(this.lastPoint);var e=b.tan(this.camera.fieldOfView/360*b.PI);e=this.height/2/this.camera.zoom/e;e=this.camera.focalLength()/e;h.translate(this.camera.viewMatrix,[d.x*e,-d.y*e,0]);this.lastPoint=a.p;this.repaint()}else this.lastPoint=
a.p,this.lastPoint.multi=!0};a.gesturechange=function(a){if(0!==a.originalEvent.scale-this.lastPinchScale){let b=30*-(a.originalEvent.scale/this.lastPinchScale-1);if(isNaN(b))return;0<b?this.camera.zoomOut():this.camera.zoomIn();this.updateScene();this.lastPinchScale=a.originalEvent.scale}this.repaint()};a.gestureend=function(a){this.lastPinchScale=1;this.lastGestureRotate=0}})(ChemDoodle,ChemDoodle.extensions,ChemDoodle.math,ChemDoodle.structures,ChemDoodle.structures.d3,ChemDoodle.RESIDUE,Math,
document,ChemDoodle.lib.mat4,ChemDoodle.lib.mat3,ChemDoodle.lib.vec3,ChemDoodle.lib.jQuery,window);
(function(f,q,n,r,e){f.MolGrabberCanvas3D=function(e,b,d){e&&this.create(e,b,d);b=[];b.push('\x3cbr\x3e\x3cinput type\x3d"text" id\x3d"');b.push(e);b.push('_query" size\x3d"32" value\x3d"" /\x3e');b.push("\x3cbr\x3e\x3cnobr\x3e");b.push('\x3cselect id\x3d"');b.push(e);b.push('_select"\x3e');b.push('\x3coption value\x3d"pubchem" selected\x3ePubChem');b.push("\x3c/select\x3e");b.push('\x3cbutton type\x3d"button" id\x3d"');b.push(e);b.push('_submit"\x3eShow Molecule\x3c/button\x3e');b.push("\x3c/nobr\x3e");
r.writeln(b.join(""));let f=this;n("#"+e+"_submit").click(function(){f.search()});n("#"+e+"_query").keypress(function(a){13===a.which&&f.search()})};f=f.MolGrabberCanvas3D.prototype=new f._Canvas3D;f.setSearchTerm=function(e){n("#"+this.id+"_query").val(e);this.search()};f.search=function(){let e=this;q.getMoleculeFromDatabase(n("#"+this.id+"_query").val(),{database:n("#"+this.id+"_select").val(),dimension:3},function(b){e.loadMolecule(b)})}})(ChemDoodle,ChemDoodle.iChemLabs,ChemDoodle.lib.jQuery,
document);
(function(f,q,n){f.MovieCanvas3D=function(f,e,k){f&&this.create(f,e,k);this.frames=[]};f.MovieCanvas3D.PLAY_ONCE=0;f.MovieCanvas3D.PLAY_LOOP=1;f.MovieCanvas3D.PLAY_SPRING=2;n=f.MovieCanvas3D.prototype=new f._Canvas3D;n.timeout=50;n.frameNumber=0;n.playMode=2;n.reverse=!1;n.startAnimation=f._AnimatorCanvas.prototype.startAnimation;n.stopAnimation=f._AnimatorCanvas.prototype.stopAnimation;n.isRunning=f._AnimatorCanvas.prototype.isRunning;n.dblclick=f.RotatorCanvas.prototype.dblclick;n.nextFrame=function(f){f=
this.frames[this.frameNumber];this.molecules=f.mols;this.shapes=f.shapes;2===this.playMode&&this.reverse?(this.frameNumber--,0>this.frameNumber&&(this.frameNumber=1,this.reverse=!1)):(this.frameNumber++,this.frameNumber>=this.frames.length&&(2===this.playMode?(this.frameNumber-=2,this.reverse=!0):(this.frameNumber=0,0===this.playMode&&this.stopAnimation())))};n.center=function(){var f=new q.Atom,e=this.frames[0];for(let k=0,b=e.mols.length;k<b;k++)f.add3D(e.mols[k].getCenter3D());f.x/=e.mols.length;
f.y/=e.mols.length;e=new q.Atom;e.sub3D(f);for(let k=0,b=this.frames.length;k<b;k++){f=this.frames[k];for(let b=0,h=f.mols.length;b<h;b++){let a=f.mols[b];for(let b=0,d=a.atoms.length;b<d;b++)a.atoms[b].add3D(e)}}};n.addFrame=function(f,e){this.frames.push({mols:f,shapes:e})}})(ChemDoodle,ChemDoodle.structures);
(function(f,q,n,r){let e=[],k=[1,0,0],b=[0,1,0],d=[0,0,1];f.RotatorCanvas3D=function(a,b,d){a&&this.create(a,b,d)};let h=f.RotatorCanvas3D.prototype=new f._Canvas3D;h.timeout=33;q=q.PI/15;h.xIncrement=q;h.yIncrement=q;h.zIncrement=q;h.startAnimation=f._AnimatorCanvas.prototype.startAnimation;h.stopAnimation=f._AnimatorCanvas.prototype.stopAnimation;h.isRunning=f._AnimatorCanvas.prototype.isRunning;h.dblclick=f.RotatorCanvas.prototype.dblclick;h.mousedown=r;h.rightmousedown=r;h.drag=r;h.mousewheel=
r;h.nextFrame=function(a){0===this.molecules.length&&0===this.shapes.length?this.stopAnimation():(n.identity(e),a/=1E3,n.rotate(e,this.xIncrement*a,k),n.rotate(e,this.yIncrement*a,b),n.rotate(e,this.zIncrement*a,d),n.multiply(this.rotationMatrix,e))}})(ChemDoodle,Math,ChemDoodle.lib.mat4);(function(f,q){f.TransformCanvas3D=function(f,q,e){f&&this.create(f,q,e)};f.TransformCanvas3D.prototype=new f._Canvas3D})(ChemDoodle);
(function(f,q){f.ViewerCanvas3D=function(f,q,e){f&&this.create(f,q,e)};f=f.ViewerCanvas3D.prototype=new f._Canvas3D;f.mousedown=q;f.rightmousedown=q;f.drag=q;f.mousewheel=q})(ChemDoodle);
(function(f,q,n,r,e){function k(b,d,e,a){this.element=b;this.x=d;this.y=e;this.dimension=a;this.allowMultipleSelections=!1}f.PeriodicTableCanvas=function(b,d){this.padding=5;b&&this.create(b,18*d+2*this.padding,10*d+2*this.padding);this.cellDimension=d?d:20;this.setupTable();this.repaint()};r=f.PeriodicTableCanvas.prototype=new f._Canvas;r.loadMolecule=e;r.getMolecule=e;r.getHoveredElement=function(){return this.hovered?this.hovered.element:e};r.innerRepaint=function(b){for(let d=0,e=this.cells.length;d<
e;d++)this.drawCell(b,this.styles,this.cells[d]);this.hovered&&this.drawCell(b,this.styles,this.hovered);this.selected&&this.drawCell(b,this.styles,this.selected)};r.setupTable=function(){this.cells=[];let b=this.padding,d=this.padding;var e=0;for(let g=0,h=f.SYMBOLS.length;g<h;g++){18===e&&(e=0,d+=this.cellDimension,b=this.padding);var a=f.ELEMENT[f.SYMBOLS[g]];if(2===a.atomicNumber)b+=16*this.cellDimension,e+=16;else if(5===a.atomicNumber||13===a.atomicNumber)b+=10*this.cellDimension,e+=10;(58>
a.atomicNumber||71<a.atomicNumber&&90>a.atomicNumber||103<a.atomicNumber)&&118>=a.atomicNumber&&(this.cells.push(new k(a,b,d,this.cellDimension)),b+=this.cellDimension,e++)}d+=2*this.cellDimension;b=3*this.cellDimension+this.padding;for(e=57;104>e;e++)if(a=f.ELEMENT[f.SYMBOLS[e]],90===a.atomicNumber&&(d+=this.cellDimension,b=3*this.cellDimension+this.padding),58<=a.atomicNumber&&71>=a.atomicNumber||90<=a.atomicNumber&&103>=a.atomicNumber)this.cells.push(new k(a,b,d,this.cellDimension)),b+=this.cellDimension};
r.drawCell=function(b,d,e){let a=b.createRadialGradient(e.x+e.dimension/3,e.y+e.dimension/3,1.5*e.dimension,e.x+e.dimension/3,e.y+e.dimension/3,e.dimension/10);a.addColorStop(0,"#000000");a.addColorStop(.7,e.element.jmolColor);a.addColorStop(1,"#FFFFFF");b.fillStyle=a;q.contextRoundRect(b,e.x,e.y,e.dimension,e.dimension,e.dimension/8);if(e===this.hovered||e===this.selected||e.selected)b.lineWidth=2,b.strokeStyle="#c10000",b.stroke(),b.fillStyle="white";b.fill();b.font=q.getFontString(d.text_font_size,
d.text_font_families);b.fillStyle=d.text_color;b.textAlign="center";b.textBaseline="middle";b.fillText(e.element.symbol,e.x+e.dimension/2,e.y+e.dimension/2)};r.click=function(b){this.hovered&&(this.allowMultipleSelections?this.hovered.selected=!this.hovered.selected:this.selected=this.hovered,this.repaint())};r.touchstart=function(b){this.mousemove(b)};r.mousemove=function(b){let d=b.p.x;b=b.p.y;this.hovered=e;for(let e=0,a=this.cells.length;e<a;e++){let a=this.cells[e];if(n.isBetween(d,a.x,a.x+a.dimension)&&
n.isBetween(b,a.y,a.y+a.dimension)){this.hovered=a;break}}this.repaint()};r.mouseout=function(b){this.hovered=e;this.repaint()}})(ChemDoodle,ChemDoodle.extensions,ChemDoodle.math,document);(function(f,q,n,r){f.png={};f.png.string=function(e){return q.getElementById(e.id).toDataURL("image/png")};f.png.open=function(e){n.open(this.string(e))}})(ChemDoodle.io,document,window);(function(f,q,n){f.file={};f.file.content=function(f,e){q.get(f,"",e)}})(ChemDoodle.io,ChemDoodle.lib.jQuery);
(function(f,q,n,r,e,k,b){q.SERVER_URL="https://ichemlabs.cloud.chemdoodle.com/icl_cdc_v090000/WebHQ";q.inRelay=!1;q.asynchronous=!0;q.INFO={userAgent:navigator.userAgent,platform:navigator.platform,v_cwc:f.getVersion(),v_jQuery:e.fn.jquery,v_jQuery_ui:"N/A"};let d=new n.JSONInterpreter,h=new r.Queue;q._contactServer=function(a,b,d,f,m){this.inRelay?h.enqueue({call:a,content:b,options:d,callback:f,errorback:m}):(q.inRelay=!0,e.ajax({dataType:"text",type:"POST",data:JSON.stringify({call:a,content:b,
options:d,info:q.INFO}),url:this.SERVER_URL,success:function(a){a=JSON.parse(a);a.message&&alert(a.message);q.inRelay=!1;f&&a.content&&!a.stop&&f(a.content);a.stop&&m&&m();h.isEmpty()||(a=h.dequeue(),q._contactServer(a.call,a.content,a.options,a.callback,a.errorback))},error:function(a,b,d){q.inRelay=!1;m&&m();h.isEmpty()||(a=h.dequeue(),q._contactServer(a.call,a.content,a.options,a.callback,a.errorback))},xhrFields:{withCredentials:!0},async:q.asynchronous}))};q.authenticate=function(a,b,d,e){this._contactServer("authenticate",
{credential:a},b,function(a){d(a)},e)};q.balanceReaction=function(a,b,e,f){let g={};"string"===typeof a||a instanceof String?g.equation=a:g.reaction=d.contentTo(a.molecules,a.shapes);this._contactServer("balanceReaction",g,b,function(a){e(a.result,a.message)},f)};q.calculate=function(a,b,e,f){this._contactServer("calculate",{mol:d.molTo(a)},b,function(a){e(a)},f)};q.createLewisDotStructure=function(a,b,e,f){this._contactServer("createLewisDot",{mol:d.molTo(a)},b,function(a){e(d.molFrom(a.mol))},f)};
q.generateImage=function(a,b,e,f){this._contactServer("generateImage",{mol:d.molTo(a)},b,function(a){e(a.link)},f)};q.generateIUPACName=function(a,b,e,f){this._contactServer("generateIUPACName",{mol:d.molTo(a)},b,function(a){e(a.iupac)},f)};q.getMoleculeFromContent=function(a,b,e,f){this._contactServer("getMoleculeFromContent",{content:a},b,function(a){let b=!1;for(let d=0,e=a.mol.a.length;d<e;d++)if(0!==a.mol.a[d].z){b=!0;break}if(b)for(let b=0,d=a.mol.a.length;b<d;b++)a.mol.a[b].x/=20,a.mol.a[b].y/=
20,a.mol.a[b].z/=20;e(d.molFrom(a.mol))},f)};q.getMoleculeFromDatabase=function(a,b,e,f){this._contactServer("getMoleculeFromDatabase",{query:a},b,function(a){if(3===b.dimension)for(let b=0,d=a.mol.a.length;b<d;b++)a.mol.a[b].x/=20,a.mol.a[b].y/=-20,a.mol.a[b].z/=20;e(d.molFrom(a.mol))},f)};q.getOptimizedPDBStructure=function(a,b,e,f){this._contactServer("getOptimizedPDBStructure",{id:a},b,function(a){let b;b=a.mol?d.molFrom(a.mol):new r.Molecule;b.chains=d.chainsFrom(a.ribbons);for(let d=0,e=b.chains.length;d<
e;d++){a=b.chains[d];for(let b=0,d=a.length-1;b<d;b++)a[b+1].arrow&&(a[b+1].arrow=!1,a[b].arrow=!0)}b.fromJSON=!0;e(b)},f)};q.getZeoliteFromIZA=function(a,b,d,e){this._contactServer("getZeoliteFromIZA",{query:a},b,function(a){d(ChemDoodle.readCIF(a.cif,b.xSuper,b.ySuper,b.zSuper))},e)};q.isGraphIsomorphism=function(a,b,e,f,h){this._contactServer("isGraphIsomorphism",{arrow:d.molTo(a),target:d.molTo(b)},e,function(a){f(a.value)},h)};q.isSubgraphIsomorphism=function(a,b,e,f,h){this._contactServer("isSubgraphIsomorphism",
{arrow:d.molTo(a),target:d.molTo(b)},e,function(a){f(a.value)},h)};q.isSupergraphIsomorphism=function(a,b,e,f,h){this._contactServer("isSupergraphIsomorphism",{arrow:d.molTo(a),target:d.molTo(b)},e,function(a){f(a.value)},h)};q.getSimilarityMeasure=function(a,b,e,f,h){this._contactServer("getSimilarityMeasure",{first:d.molTo(a),second:d.molTo(b)},e,function(a){f(a.value)},h)};q.kekulize=function(a,b,e,f){this._contactServer("kekulize",{mol:d.molTo(a)},b,function(a){e(d.molFrom(a.mol))},f)};q.maximumCommonSubstructure=
function(a,b,e,f,h){this._contactServer("maximumCommonSubstructure",{m1:d.molTo(a),m2:d.molTo(b)},e,function(a){f(a.map)},h)};q.mechanismMatch=function(a,b,d,e,f){this._contactServer("matchMechanism",{arrow:a,targets:b},d,function(a){e(a)},f)};q.optimize=function(a,b,e,f){this._contactServer("optimize",{mol:d.molTo(a)},b,function(f){f=d.molFrom(f.mol);if(2===b.dimension){for(let b=0,d=f.atoms.length;b<d;b++)a.atoms[b].x=f.atoms[b].x,a.atoms[b].y=f.atoms[b].y;e()}else if(3===b.dimension){for(let a=
0,b=f.atoms.length;a<b;a++)f.atoms[a].x/=20,f.atoms[a].y/=-20,f.atoms[a].z/=20;e(f)}},f)};q.readIUPACName=function(a,b,e,f){this._contactServer("readIUPACName",{iupac:a},b,function(a){e(d.molFrom(a.mol))},f)};q.readSMILES=function(a,b,e,f){this._contactServer("readSMILES",{smiles:a},b,function(a){e(d.molFrom(a.mol))},f)};q.resolveCIP=function(a,b,e,f){this._contactServer("resolveCIP",{mol:d.molTo(a)},b,function(a){e(a.atoms,a.bonds)},f)};q.saveFile=function(a,b,e,f){this._contactServer("saveFile",
{mol:d.molTo(a)},b,function(a){e(a.link)},f)};q.simulate13CNMR=function(a,b,e,h){b.nucleus="C";b.isotope=13;this._contactServer("simulateNMR",{mol:d.molTo(a)},b,function(a){e(f.readJCAMP(a.jcamp))},h)};q.simulate1HNMR=function(a,b,e,h){b.nucleus="H";b.isotope=1;this._contactServer("simulateNMR",{mol:d.molTo(a)},b,function(a){e(f.readJCAMP(a.jcamp))},h)};q.simulateMassParentPeak=function(a,b,e,h){this._contactServer("simulateMassParentPeak",{mol:d.molTo(a)},b,function(a){e(f.readJCAMP(a.jcamp))},h)};
q.writeSMILES=function(a,b,e,f){this._contactServer("writeSMILES",{mol:d.molTo(a)},b,function(a){e(a.smiles)},f)};q.version=function(a,b,d){this._contactServer("version",{},a,function(a){b(a.value)},d)};q.checkForUpdates=function(a){this._contactServer("checkForUpdates",{value:k.href},a,function(a){},function(){})}})(ChemDoodle,ChemDoodle.iChemLabs,ChemDoodle.io,ChemDoodle.structures,ChemDoodle.lib.jQuery,location);